iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eeu-035051

UUCD1 version

UUC-ErE-00286

Ensembl Protein ID

ENSEEUP00000000631.1

UniProt Accession

A0A088MSU7; A0A088MSU7_ERIEU

Genbank Protein ID

AIN37116.1

Protein Name

Recombination activating protein 1

Genbank Nucleotide ID

KF783026

Gene Name

RNF166; RAG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSEEUG00000000713.1	ENSEEUT00000000713.1	ENSEEUP00000000631.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-06	28.4	33	73
E3 activity/RING/U-box	2.70e-06	26.9	30	89

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCle + +++ +++CgH+f+ +Clq       ++ ++ +CPlCr
   Q: 33   CPICLEVYHRPVAIGSCGHTFCGECLQPC-----LQVPSPLCPLCR 73
           **********999************9444.....799********8 PP

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedl.vPnltlr 62
           ++ CpI le+ + Pv +  +G+t+  ++++ +l+     cP++r p++++++ +  ++ +
   Q: 30   QYSCPICLEVYHRPVAIGsCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVdKAAHVEK 89
           789************9877****************************9988755555555 PP

Organism

Erinaceus europaeus

Protein Sequence
(Fasta)

MAMFRSLVAS AQQRQPSGGP ASGDSGLEAQ YSCPICLEVY HRPVAIGSCG HTFCGECLQP 60
CLQVPSPLCP LCRLPFDPKK VDKAAHVEKQ LSAYKAPCRG CNKKVTLAKM RVHVSSCMKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGATGT TCCGTAGCCT AGTGGCCTCG GCACAGCAAC GGCAGCCTTC TGGCGGGCCT 60
GCGAGTGGAG ACAGCGGCCT GGAGGCGCAG TATAGCTGCC CCATCTGCCT GGAGGTCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0539--Nucleus

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033151--P:V(D)J recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002042	Ailuropoda melanoleuca	70.79	7.00e-70	256.00
IUUC-Apl-003816	Anas platyrhynchos	70.98	5.00e-75	273.00
IUUC-Aca-005379	Anolis carolinensis	87.18	3.00e-103	367.00
IUUC-Acl-008013	Aspergillus clavatus	45.45	3.00e-05	44.30
IUUC-Ani-009293	Aspergillus nidulans	44.44	6.00e-06	46.20
IUUC-Ame-011339	Astyanax mexicanus	86.98	1.00e-89	321.00
IUUC-Bta-012575	Bos taurus	95.02	1.00e-117	414.00
IUUC-Cja-019772	Callithrix jacchus	77.51	1.00e-74	271.00
IUUC-Cfa-021271	Canis familiaris	97.29	2.00e-119	421.00
IUUC-Cpo-022471	Cavia porcellus	94.57	2.00e-125	440.00
IUUC-Csa-023435	Chlorocebus sabaeus	94.12	1.00e-125	441.00
IUUC-Dre-027458	Danio rerio	80.44	5.00e-108	382.00
IUUC-Dor-030798	Dipodomys ordii	94.87	3.00e-65	239.00
IUUC-Eca-033686	Equus caballus	95.86	4.00e-97	345.00
IUUC-Fca-035399	Felis catus	91.58	8.00e-103	365.00
IUUC-Fal-036707	Ficedula albicollis	88.44	7.00e-92	328.00
IUUC-Gga-040346	Gallus gallus	88.21	8.00e-105	372.00
IUUC-Gac-042409	Gasterosteus aculeatus	56.25	4.00e-48	183.00
IUUC-Ggo-045264	Gorilla gorilla	94.12	1.00e-125	441.00
IUUC-Hsa-046649	Homo sapiens	94.12	1.00e-125	441.00
IUUC-Itr-048243	Ictidomys tridecemlineatus	94.08	7.00e-95	338.00
IUUC-Loc-052767	Lepisosteus oculatus	71.83	3.00e-102	363.00
IUUC-Laf-053402	Loxodonta africana	95.48	2.00e-126	444.00
IUUC-Mcc-055236	Macaca mulatta	81.53	3.00e-101	360.00
IUUC-Mga-059430	Meleagris gallopavo	88.57	2.00e-93	333.00
IUUC-Mmr-061214	Microcebus murinus	94.57	3.00e-125	440.00
IUUC-Mdo-062112	Monodelphis domestica	85.53	2.00e-115	407.00
IUUC-Mmu-063307	Mus musculus	93.67	5.00e-125	439.00
IUUC-Mpu-066881	Mustela putorius furo	96.45	5.00e-97	346.00
IUUC-Mlu-067382	Myotis lucifugus	95.86	1.00e-96	344.00
IUUC-Nle-069388	Nomascus leucogenys	88.24	8.00e-115	405.00
IUUC-Oan-072786	Ornithorhynchus anatinus	89.47	3.00e-78	283.00
IUUC-Ola-087498	Oryzias latipes	81.03	9.00e-99	352.00
IUUC-Oga-088354	Otolemur garnettii	87.23	9.00e-121	425.00
IUUC-Oar-090300	Ovis aries	94.44	6.00e-114	402.00
IUUC-Ptr-090594	Pan troglodytes	94.12	1.00e-125	441.00
IUUC-Pan-091714	Papio anubis	94.12	1.00e-125	441.00
IUUC-Psi-093536	Pelodiscus sinensis	89.94	8.00e-92	328.00
IUUC-Pma-094178	Petromyzon marinus	45.69	3.00e-51	193.00
IUUC-Pfo-096266	Poecilia formosa	75.88	4.00e-103	366.00
IUUC-Pab-098752	Pongo abelii	94.67	1.00e-95	341.00
IUUC-Pca-101015	Procavia capensis	94.87	4.00e-65	238.00
IUUC-Pva-102695	Pteropus vampyrus	95.02	2.00e-117	414.00
IUUC-Rno-104836	Rattus norvegicus	93.67	5.00e-125	439.00
IUUC-Sha-106920	Sarcophilus harrisii	79.44	1.00e-114	405.00
IUUC-Tgu-117434	Taeniopygia guttata	90.53	9.00e-92	328.00
IUUC-Tru-118479	Takifugu rubripes	75.00	8.00e-104	369.00
IUUC-Tni-119994	Tetraodon nigroviridis	53.78	2.00e-66	244.00
IUUC-Ttr-129306	Tursiops truncatus	78.28	2.00e-90	324.00
IUUC-Xtr-132746	Xenopus tropicalis	84.07	1.00e-109	388.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence