iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	miRNAMap	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	Phospho.ELM	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	15530417

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	9.90e-06	26.3	43	84

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl+++k+ p++lpC+H+f+  Cl+      +   ++ +CP Cr
   Q: 43   CPICLDRYKQ-PKLLPCQHTFCYPCLESC---ADTLHRNLKCPECR 84
           ********99.***************555...688999*******8 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MSSSPQNEAE AREKMRELMS RPPSSRPADF VNPLEKIEQL LTCPICLDRY KQPKLLPCQH 60
TFCYPCLESC ADTLHRNLKC PECRAEHNIP YDGVKAFQPN YTLTGFLEIH LQATPESAAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTTATTAT TATATTCGAT TCGTCTTCTC GTTCTATCCT GTTTTTTTTT AATTCGAAAT 60
TCCAATATTT CTAAAATTCA ATCCTTATGA GCAGTTCTCC ACAAAATGAA GCAGAAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001258--NHL_repeat
IPR013017--NHL_repeat_subgr
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51125--NHL
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01436--NHL
PF00097--zf-C3HC4

SMART

SM00184--RING

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000755	Aegilops tauschii	39.22	5.00e-08	51.20
IUUC-Atr-002992	Amborella trichopoda	43.14	4.00e-08	50.80
IUUC-Ate-010344	Aspergillus terreus	39.62	1.00e-09	57.40
IUUC-Bgr-012267	Blumeria graminis	34.44	1.00e-08	53.90
IUUC-Bci-013692	Botrytis cinerea	34.52	1.00e-08	53.90
IUUC-Cin-025629	Ciona intestinalis	54.72	4.00e-54	201.00
IUUC-Csv-026112	Ciona savignyi	32.76	2.00e-27	116.00
IUUC-Cgl-026521	Colletotrichum gloeosporioides	29.66	2.00e-06	46.60
IUUC-Dse-031151	Dothistroma septosporum	33.67	1.00e-06	47.40
IUUC-Dme-031840	Drosophila melanogaster	51.46	1.00e-78	287.00
IUUC-Gmo-039689	Gadus morhua	35.90	2.00e-42	166.00
IUUC-Gac-042586	Gasterosteus aculeatus	36.86	7.00e-42	164.00
IUUC-Gma-043819	Glycine max	24.71	2.00e-09	57.00
IUUC-Lch-050455	Latimeria chalumnae	49.38	9.00e-68	249.00
IUUC-Lma-053260	Leptosphaeria maculans	41.38	2.00e-09	57.00
IUUC-Mtr-058007	Medicago truncatula	43.14	2.00e-08	52.40
IUUC-Nfi-068546	Neosartorya fischeri	36.11	9.00e-09	54.70
IUUC-Oba-075953	Oryza barthii	48.78	1.00e-06	47.00
IUUC-Ogl-076938	Oryza glaberrima	48.78	1.00e-06	47.00
IUUC-Ogu-078203	Oryza glumaepatula	37.25	6.00e-07	47.00
IUUC-Oni-082364	Oryza nivara	48.78	1.00e-06	47.00
IUUC-Osa-085434	Oryza sativa	48.78	1.00e-06	47.00
IUUC-Olu-087666	Ostreococcus lucimarinus	34.88	2.00e-08	52.80
IUUC-Pma-094356	Petromyzon marinus	46.48	2.00e-61	228.00
IUUC-Pca-100644	Procavia capensis	39.66	8.00e-31	127.00
IUUC-Ppe-102024	Prunus persica	41.25	5.00e-08	52.40
IUUC-Pte-104339	Pyrenophora teres	40.00	4.00e-10	58.90
IUUC-Pyt-104522	Pyrenophora triticirepentis	40.00	3.00e-10	59.30
IUUC-Sce-106362	Saccharomyces cerevisiae	40.74	6.00e-08	50.40
IUUC-Smo-109550	Selaginella moellendorffii	41.67	6.00e-07	48.50
IUUC-Stu-112446	Solanum tuberosum	41.18	4.00e-08	51.20
IUUC-Tca-121809	Theobroma cacao	43.10	2.00e-09	56.20
IUUC-Tae-123092	Triticum aestivum	39.22	5.00e-08	51.20
IUUC-Tur-126688	Triticum urartu	39.22	7.00e-08	50.10
IUUC-Ttr-128336	Tursiops truncatus	36.26	5.00e-42	164.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence