iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089684

Ensembl Protein ID

ENSOARP00000013073.1

UniProt Accession

W5PRJ4; W5PRJ4_SHEEP

Genbank Protein ID

ENSOARP00000013073

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01048982

Gene Name

VCP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000012193.1	ENSOART00000013263.1	ENSOARP00000013073.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Other/Other	97.28	0.00e+00	1487.00	IUUC-Hsa-046162
UBD/Other/Other	70.53	0.00e+00	1097.00	IUUC-Sce-106244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

SFSLSSSKGD DLSTAILKQK NRPNRLIVDE AINEDNSVVS LSQPKMDELQ LFRGDTVLLK 60
GKKRREAVCI VLSDDTCSDE KIRMNRVVRN NLRVHLGDVI SIQPCPDVKY GKRIHVLPID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTTTTCTC TTTCTAGTTC AAAAGGCGAT GATTTATCAA CAGCCATTCT TAAACAGAAA 60
AACCGTCCCA ATCGGTTAAT TGTTGATGAA GCCATCAATG AGGACAACAG TGTGGTATCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR003593--AAA+_ATPase
IPR005938--AAA_ATPase_CDC48
IPR009010--Asp_de-COase-like_dom
IPR003959--ATPase_AAA_core
IPR003960--ATPase_AAA_CS
IPR004201--Cdc48_dom2
IPR029067--CDC48_domain_2-like
IPR003338--CDC4_N-term_subdom
IPR027417--P-loop_NTPase
IPR015415--Vps4_C

PROSITE

PS00674--AAA

Pfam

PF00004--AAA
PF02933--CDC48_2
PF02359--CDC48_N
PF09336--Vps4_C

SMART

SM00382--AAA
SM01072--CDC48_2
SM01073--CDC48_N

Gene Ontology

GO:0005829--C:cytosol
GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0070062--C:extracellular exosome
GO:0005811--C:lipid particle
GO:0043209--C:myelin sheath
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0000502--C:proteasome complex
GO:0035861--C:site of double-strand break
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1990730--C:VCP-NSFL1C complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0035800--F:deubiquitinase activator activity
GO:0003723--F:RNA binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070842--P:aggresome assembly
GO:0046034--P:ATP metabolic process
GO:0097352--P:autophagosome maturation
GO:0006302--P:double-strand break repair
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0072389--P:flavin adenine dinucleotide catabolic process
GO:0006734--P:NADH metabolic process
GO:2001171--P:positive regulation of ATP biosynthetic process
GO:1903007--P:positive regulation of Lys63-specific deubiquitinase activity
GO:0010918--P:positive regulation of mitochondrial membrane potential
GO:1903862--P:positive regulation of oxidative phosphorylation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031334--P:positive regulation of protein complex assembly
GO:0034214--P:protein hexamerization
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0016567--P:protein ubiquitination
GO:1903715--P:regulation of aerobic respiration
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0019985--P:translesion synthesis
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0019079--P:viral genome replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000524	Aegilops tauschii	80.45	0.00e+00	1195.00
IUUC-Aml-001849	Ailuropoda melanoleuca	98.15	0.00e+00	1500.00
IUUC-Atr-002619	Amborella trichopoda	80.00	0.00e+00	1241.00
IUUC-Apl-004070	Anas platyrhynchos	96.66	0.00e+00	1469.00
IUUC-Aca-004847	Anolis carolinensis	96.28	0.00e+00	1471.00
IUUC-Aly-005406	Arabidopsis lyrata	79.10	0.00e+00	1215.00
IUUC-Ath-006796	Arabidopsis thaliana	79.82	0.00e+00	1224.00
IUUC-Ago-008001	Ashbya gossypii	71.43	0.00e+00	1039.00
IUUC-Acl-008066	Aspergillus clavatus	73.52	0.00e+00	1100.00
IUUC-Afl-008505	Aspergillus flavus	73.16	0.00e+00	1122.00
IUUC-Afu-008840	Aspergillus fumigatus	73.91	0.00e+00	1122.00
IUUC-Ani-009368	Aspergillus nidulans	73.22	0.00e+00	1129.00
IUUC-Ang-009724	Aspergillus niger	73.39	0.00e+00	1125.00
IUUC-Aor-010204	Aspergillus oryzae	73.16	0.00e+00	1122.00
IUUC-Ate-010370	Aspergillus terreus	73.68	0.00e+00	1126.00
IUUC-Ame-011388	Astyanax mexicanus	93.83	0.00e+00	1423.00
IUUC-Bgr-012223	Blumeria graminis	72.15	0.00e+00	1136.00
IUUC-Bta-013188	Bos taurus	97.78	0.00e+00	1491.00
IUUC-Bci-013831	Botrytis cinerea	73.08	0.00e+00	1122.00
IUUC-Bdi-014967	Brachypodium distachyon	80.58	0.00e+00	1234.00
IUUC-Bol-016113	Brassica oleracea	79.79	0.00e+00	1225.00
IUUC-Bra-017796	Brassica rapa	79.79	0.00e+00	1228.00
IUUC-Cel-018243	Caenorhabditis elegans	79.30	0.00e+00	1203.00
IUUC-Cja-019904	Callithrix jacchus	96.91	0.00e+00	1437.00
IUUC-Cfa-020304	Canis familiaris	97.78	0.00e+00	1489.00
IUUC-Cpo-021518	Cavia porcellus	97.66	0.00e+00	1487.00
IUUC-Cre-022719	Chlamydomonas reinhardtii	79.63	0.00e+00	1219.00
IUUC-Csa-023444	Chlorocebus sabaeus	97.65	0.00e+00	1485.00
IUUC-Cho-024482	Choloepus hoffmanni	96.65	0.00e+00	1455.00
IUUC-Cin-025517	Ciona intestinalis	86.07	0.00e+00	1276.00
IUUC-Csv-026060	Ciona savignyi	86.58	0.00e+00	1328.00
IUUC-Cgl-026690	Colletotrichum gloeosporioides	73.38	0.00e+00	1150.00
IUUC-Cne-026910	Cryptococcus neoformans	71.80	0.00e+00	1164.00
IUUC-Cme-027145	Cyanidioschyzon merolae	75.51	0.00e+00	1157.00
IUUC-Dre-028487	Danio rerio	94.07	0.00e+00	1424.00
IUUC-Dno-029257	Dasypus novemcinctus	97.65	0.00e+00	1485.00
IUUC-Dor-030473	Dipodomys ordii	96.05	0.00e+00	1434.00
IUUC-Dse-031319	Dothistroma septosporum	71.37	0.00e+00	1095.00
IUUC-Dme-032203	Drosophila melanogaster	84.70	0.00e+00	1274.00
IUUC-Eca-033311	Equus caballus	97.53	0.00e+00	1483.00
IUUC-Eeu-035293	Erinaceus europaeus	98.23	0.00e+00	763.00
IUUC-Fca-036097	Felis catus	100.00	0.00e+00	1395.00
IUUC-Fal-037292	Ficedula albicollis	97.28	0.00e+00	1476.00
IUUC-Fox-037827	Fusarium oxysporum	73.48	0.00e+00	1147.00
IUUC-Fso-038226	Fusarium solani	73.44	0.00e+00	1155.00
IUUC-Gmo-039157	Gadus morhua	87.10	0.00e+00	1304.00
IUUC-Ggr-039951	Gaeumannomyces graminis	73.14	0.00e+00	1123.00
IUUC-Gga-041183	Gallus gallus	97.16	0.00e+00	1475.00
IUUC-Gac-042039	Gasterosteus aculeatus	93.58	0.00e+00	1414.00
IUUC-Gma-044090	Glycine max	76.80	0.00e+00	1249.00
IUUC-Ggo-045568	Gorilla gorilla	97.65	0.00e+00	1485.00
IUUC-Hsa-046162	Homo sapiens	97.65	0.00e+00	1485.00
IUUC-Hvu-047107	Hordeum vulgare	81.29	0.00e+00	993.00
IUUC-Itr-047885	Ictidomys tridecemlineatus	97.41	0.00e+00	1480.00
IUUC-Kpa-049220	Komagataella pastoris	70.53	0.00e+00	1098.00
IUUC-Lch-050657	Latimeria chalumnae	87.36	0.00e+00	1274.00
IUUC-Lpe-051083	Leersia perrieri	80.18	0.00e+00	1223.00
IUUC-Loc-052064	Lepisosteus oculatus	94.32	0.00e+00	1429.00
IUUC-Lma-053323	Leptosphaeria maculans	73.86	0.00e+00	1134.00
IUUC-Laf-054574	Loxodonta africana	98.02	0.00e+00	1488.00
IUUC-Mcc-055448	Macaca mulatta	97.65	0.00e+00	1485.00
IUUC-Meu-056316	Macropus eugenii	90.32	0.00e+00	1345.00
IUUC-Mor-057057	Magnaporthe oryzae	72.98	0.00e+00	1118.00
IUUC-Mpo-057406	Magnaporthe poae	73.40	0.00e+00	1116.00
IUUC-Mtr-057648	Medicago truncatula	79.79	0.00e+00	1243.00
IUUC-Mla-059156	Melampsora laricipopulina	76.51	0.00e+00	1204.00
IUUC-Mga-060004	Meleagris gallopavo	90.78	0.00e+00	1238.00
IUUC-Mvi-060488	Microbotryum violaceum	75.51	0.00e+00	1186.00
IUUC-Mmr-061027	Microcebus murinus	97.66	0.00e+00	1485.00
IUUC-Mdo-062159	Monodelphis domestica	97.28	0.00e+00	1477.00
IUUC-Mmu-063633	Mus musculus	97.65	0.00e+00	1485.00
IUUC-Mac-064919	Musa acuminata	79.42	0.00e+00	1228.00
IUUC-Mpu-066078	Mustela putorius furo	97.78	0.00e+00	1491.00
IUUC-Mlu-067757	Myotis lucifugus	97.53	0.00e+00	1485.00
IUUC-Nfi-068533	Neosartorya fischeri	73.91	0.00e+00	1115.00
IUUC-Ncr-068775	Neurospora crassa	73.83	0.00e+00	1091.00
IUUC-Nle-069424	Nomascus leucogenys	98.02	0.00e+00	1488.00
IUUC-Opr-071147	Ochotona princeps	98.70	0.00e+00	1448.00
IUUC-Ont-071351	Oreochromis niloticus	93.21	0.00e+00	1392.00
IUUC-Oan-073335	Ornithorhynchus anatinus	96.30	0.00e+00	1474.00
IUUC-Ocu-074072	Oryctolagus cuniculus	97.65	0.00e+00	1485.00
IUUC-Oba-075914	Oryza barthii	80.47	0.00e+00	1243.00
IUUC-Obr-076224	Oryza brachyantha	80.92	0.00e+00	1238.00
IUUC-Ogl-077282	Oryza glaberrima	80.76	0.00e+00	1244.00
IUUC-Ogu-078174	Oryza glumaepatula	80.47	0.00e+00	1243.00
IUUC-Oin-079103	Oryza indica	80.47	0.00e+00	1243.00
IUUC-Olo-080675	Oryza longistaminata	80.60	0.00e+00	1244.00
IUUC-Ome-081247	Oryza meridionalis	80.05	0.00e+00	1244.00
IUUC-Oni-082078	Oryza nivara	80.34	0.00e+00	1242.00
IUUC-Opu-083806	Oryza punctata	80.50	0.00e+00	1248.00
IUUC-Oru-084634	Oryza rufipogon	80.47	0.00e+00	1244.00
IUUC-Osa-085960	Oryza sativa	80.47	0.00e+00	1243.00
IUUC-Ola-086382	Oryzias latipes	93.56	0.00e+00	1394.00
IUUC-Olu-087839	Ostreococcus lucimarinus	78.47	0.00e+00	1204.00
IUUC-Oga-088037	Otolemur garnettii	97.41	0.00e+00	1474.00
IUUC-Ptr-091378	Pan troglodytes	97.65	0.00e+00	1485.00
IUUC-Pan-092849	Papio anubis	97.65	0.00e+00	1485.00
IUUC-Psi-093725	Pelodiscus sinensis	96.73	0.00e+00	1396.00
IUUC-Pma-094537	Petromyzon marinus	89.43	0.00e+00	692.00
IUUC-Pno-094915	Phaeosphaeria nodorum	77.10	0.00e+00	1078.00
IUUC-Ppa-095632	Physcomitrella patens	79.71	0.00e+00	1194.00
IUUC-Pfo-097440	Poecilia formosa	92.96	0.00e+00	1389.00
IUUC-Pab-098469	Pongo abelii	97.65	0.00e+00	1485.00
IUUC-Pop-100047	Populus trichocarpa	80.39	0.00e+00	1249.00
IUUC-Pca-100399	Procavia capensis	93.21	0.00e+00	1389.00
IUUC-Ppe-101767	Prunus persica	78.96	0.00e+00	1241.00
IUUC-Pva-102426	Pteropus vampyrus	96.91	0.00e+00	1442.00
IUUC-Pgr-103599	Puccinia graminis	73.59	0.00e+00	1185.00
IUUC-Ptt-103740	Puccinia triticina	73.71	0.00e+00	1185.00
IUUC-Pte-104030	Pyrenophora teres	73.83	0.00e+00	1113.00
IUUC-Pyt-104541	Pyrenophora triticirepentis	73.64	0.00e+00	1114.00
IUUC-Rno-105144	Rattus norvegicus	97.04	0.00e+00	1481.00
IUUC-Sce-106244	Saccharomyces cerevisiae	70.14	0.00e+00	1046.00
IUUC-Sha-106589	Sarcophilus harrisii	97.15	0.00e+00	1478.00
IUUC-Sja-107673	Schizosaccharomyces japonicus	71.19	0.00e+00	1098.00
IUUC-Spo-108247	Schizosaccharomyces pombe	72.08	0.00e+00	1076.00
IUUC-Ssl-108642	Sclerotinia sclerotiorum	72.82	0.00e+00	1113.00
IUUC-Smo-108877	Selaginella moellendorffii	79.74	0.00e+00	1231.00
IUUC-Sit-110623	Setaria italica	79.95	0.00e+00	1239.00
IUUC-Sly-111151	Solanum lycopersicum	79.19	0.00e+00	1216.00
IUUC-Stu-111959	Solanum tuberosum	79.69	0.00e+00	1243.00
IUUC-Sar-113021	Sorex araneus	98.01	0.00e+00	1484.00
IUUC-Sbi-114457	Sorghum bicolor	80.62	0.00e+00	1244.00
IUUC-Sre-115052	Sporisorium reilianum	76.87	0.00e+00	1212.00
IUUC-Ssc-116293	Sus scrofa	97.54	0.00e+00	1485.00
IUUC-Tgu-116544	Taeniopygia guttata	94.18	0.00e+00	1390.00
IUUC-Tru-117991	Takifugu rubripes	92.03	0.00e+00	994.00
IUUC-Tsy-119131	Tarsius syrichta	80.62	0.00e+00	1146.00
IUUC-Tni-120192	Tetraodon nigroviridis	91.48	0.00e+00	1378.00
IUUC-Tca-121502	Theobroma cacao	79.79	0.00e+00	1221.00
IUUC-Tre-122189	Trichoderma reesei	73.18	0.00e+00	1132.00
IUUC-Tvi-122310	Trichoderma virens	72.66	0.00e+00	1116.00
IUUC-Tae-124332	Triticum aestivum	80.45	0.00e+00	1213.00
IUUC-Tur-126733	Triticum urartu	80.18	0.00e+00	1198.00
IUUC-Tme-127147	Tuber melanosporum	72.97	0.00e+00	1111.00
IUUC-Tbe-127255	Tupaia belangeri	90.75	0.00e+00	1377.00
IUUC-Ttr-128876	Tursiops truncatus	97.26	0.00e+00	1469.00
IUUC-Uma-129448	Ustilago maydis	77.10	0.00e+00	1207.00
IUUC-Vda-129800	Verticillium dahliae	72.21	0.00e+00	1112.00
IUUC-Vpa-130573	Vicugna pacos	100.00	0.00e+00	840.00
IUUC-Vvi-131622	Vitis vinifera	80.52	0.00e+00	1246.00
IUUC-Xtr-132458	Xenopus tropicalis	98.91	0.00e+00	1392.00
IUUC-Xma-134045	Xiphophorus maculatus	93.09	0.00e+00	1389.00
IUUC-Yli-134382	Yarrowia lipolytica	72.12	0.00e+00	1127.00
IUUC-Zma-134817	Zea mays	80.36	0.00e+00	1249.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence