iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026282

UUCD1 version

UUC-CiS-00378

Ensembl Protein ID

ENSCSAVP00000017217.1

UniProt Accession

H2ZI01; H2ZI01_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000010128.1	ENSCSAVT00000017404.1	ENSCSAVP00000017216.1
ENSCSAVG00000010128.1	ENSCSAVT00000017405.1	ENSCSAVP00000017217.1
ENSCSAVG00000010128.1	ENSCSAVT00000017406.1	ENSCSAVP00000017218.1
ENSCSAVG00000010128.1	ENSCSAVT00000017407.1	ENSCSAVP00000017219.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-98	329.9	540	865

Active Site

Position(s)	Description	Evidence
834	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++l+k+l+vef gEeg d gGv++ef+al+++e++np +g f   e+++  ++ np+s+    e l  ++++G++lg+a++++ +l++
   Q: 540  KNLRKQLYVEFDGEEGADEGGVSKEFFALMVEEIFNPANGTFILVEESQLFWF-NPQSF----EGLMQYKLIGIILGLAIYNNCILEI 622
           57899*************************************99887777765.99998....79*********************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfs.vseeilgetkeeeLkpgGenipVtneNkeeYvklv 177
           ++++++yk+llg+k  + d+++++p +y+sl +++e+   d+e+  l ltf+ ++++++g t++++Lk+gG nipVt+ N++eYv+ +
   Q: 623  KFPSFVYKKLLGRKARFRDIKDLHPVIYQSLCSLLEY-TGDVEDD-LMLTFQvEHQDVFGCTHHHDLKEGGVNIPVTKLNRQEYVDMY 708
           *************************************.6788886.******5556669999************************** PP
   S: 178  veyrlkegikeqveafreGfneviplells.lFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
            ++ l+++i+eq++af  Gf+ v++++ l+ lF+++elell+cG+e++d+++l++ ++y+gg+t+ds++++ Fw+vl+e+s+ee+k++
   Q: 709  SDWLLNTSIEEQFNAFLGGFELVLSQSPLKyLFEASELELLLCGSEHYDFNALEESAEYDGGFTKDSQTVKDFWSVLHELSDEEKKTL 796
           *************************99665279******************************************************* PP
   S: 265  LqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           LqF Tgs+r+P+gG+a+lk   +++ k++ d drlP+++TCfn++ LP+Y++k++l+e Ll Ai+++kgF++
   Q: 797  LQFSTGSDRAPVGGLAKLK---MILAKNGPDsDRLPTAHTCFNVILLPDYKNKKKLRELLLKAIKYSKGFGM 865
           *******************...7888867766**************************************97 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

EESGPGESSL TMSKRTALKL RIQQFFAQLT QGCGRQHCPN ENCASNSTIK QLSCDEAAVQ 60
AIHLASSKAE LCSENHRSKI ARTDASDSIE IRMNINDKKG ISSADSSTQT IQPEQYCTTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTACATTTCA GCTTGAAACG TAGTGAGGAA AGTGGACCTG GAGAAAGTAG TCTCACGATG 60
TCCAAACGCA CTGCTCTTAA ATTGCGAATA CAGCAGTTTT TCGCCCAACT TACCCAGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002214	Ailuropoda melanoleuca	44.89	0.00e+00	698.00
IUUC-Atr-003144	Amborella trichopoda	43.78	1.00e-90	325.00
IUUC-Apl-003742	Anas platyrhynchos	44.42	0.00e+00	691.00
IUUC-Aca-004873	Anolis carolinensis	44.75	0.00e+00	696.00
IUUC-Ago-007908	Ashbya gossypii	36.87	4.00e-65	241.00
IUUC-Acl-008288	Aspergillus clavatus	35.42	6.00e-67	248.00
IUUC-Afl-008402	Aspergillus flavus	30.34	4.00e-64	237.00
IUUC-Afu-008762	Aspergillus fumigatus	35.88	6.00e-68	251.00
IUUC-Ani-009176	Aspergillus nidulans	31.24	5.00e-68	251.00
IUUC-Ang-009791	Aspergillus niger	29.39	1.00e-66	246.00
IUUC-Aor-009921	Aspergillus oryzae	30.34	3.00e-64	238.00
IUUC-Ate-010295	Aspergillus terreus	30.41	4.00e-72	265.00
IUUC-Ame-011166	Astyanax mexicanus	44.61	0.00e+00	668.00
IUUC-Bgr-011981	Blumeria graminis	35.33	2.00e-66	246.00
IUUC-Bta-013286	Bos taurus	44.83	0.00e+00	695.00
IUUC-Bci-013697	Botrytis cinerea	31.96	3.00e-54	205.00
IUUC-Cel-018150	Caenorhabditis elegans	34.36	1.00e-58	220.00
IUUC-Cja-019707	Callithrix jacchus	45.10	0.00e+00	696.00
IUUC-Cfa-020154	Canis familiaris	45.06	0.00e+00	696.00
IUUC-Cpo-021292	Cavia porcellus	45.06	0.00e+00	689.00
IUUC-Cre-022790	Chlamydomonas reinhardtii	45.91	2.00e-70	257.00
IUUC-Csa-023378	Chlorocebus sabaeus	45.10	0.00e+00	697.00
IUUC-Cho-025059	Choloepus hoffmanni	42.78	0.00e+00	639.00
IUUC-Cin-025643	Ciona intestinalis	67.50	0.00e+00	1145.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	35.01	2.00e-69	256.00
IUUC-Cme-027151	Cyanidioschyzon merolae	41.26	3.00e-90	325.00
IUUC-Dre-027901	Danio rerio	43.26	0.00e+00	656.00
IUUC-Dno-029320	Dasypus novemcinctus	45.01	0.00e+00	700.00
IUUC-Dor-030756	Dipodomys ordii	63.10	2.00e-128	451.00
IUUC-Dse-031239	Dothistroma septosporum	33.69	3.00e-61	229.00
IUUC-Dme-032035	Drosophila melanogaster	44.68	1.00e-132	466.00
IUUC-Ete-032902	Echinops telfairi	35.37	2.00e-69	255.00
IUUC-Eca-033843	Equus caballus	44.32	0.00e+00	670.00
IUUC-Eeu-035109	Erinaceus europaeus	44.02	0.00e+00	663.00
IUUC-Fca-036344	Felis catus	44.61	0.00e+00	695.00
IUUC-Fal-036747	Ficedula albicollis	44.42	0.00e+00	692.00
IUUC-Fox-037941	Fusarium oxysporum	36.67	2.00e-74	273.00
IUUC-Fso-038388	Fusarium solani	36.42	4.00e-74	271.00
IUUC-Gmo-038840	Gadus morhua	40.98	1.00e-178	618.00
IUUC-Ggr-040110	Gaeumannomyces graminis	39.01	7.00e-72	264.00
IUUC-Gga-040399	Gallus gallus	44.42	0.00e+00	692.00
IUUC-Gac-041933	Gasterosteus aculeatus	43.94	0.00e+00	645.00
IUUC-Ggo-044804	Gorilla gorilla	45.10	0.00e+00	696.00
IUUC-Hsa-045727	Homo sapiens	45.10	0.00e+00	696.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	42.79	0.00e+00	641.00
IUUC-Kpa-049152	Komagataella pastoris	33.58	4.00e-51	194.00
IUUC-Lch-050197	Latimeria chalumnae	51.38	0.00e+00	650.00
IUUC-Loc-052743	Lepisosteus oculatus	43.44	0.00e+00	677.00
IUUC-Lma-053245	Leptosphaeria maculans	33.16	1.00e-48	187.00
IUUC-Laf-053615	Loxodonta africana	44.84	0.00e+00	700.00
IUUC-Mcc-054934	Macaca mulatta	45.10	0.00e+00	697.00
IUUC-Meu-056061	Macropus eugenii	50.92	0.00e+00	646.00
IUUC-Mor-057045	Magnaporthe oryzae	34.61	2.00e-69	256.00
IUUC-Mla-059187	Melampsora laricipopulina	36.66	4.00e-61	226.00
IUUC-Mga-059271	Meleagris gallopavo	44.42	0.00e+00	690.00
IUUC-Mmr-061288	Microcebus murinus	44.78	0.00e+00	694.00
IUUC-Mdo-062975	Monodelphis domestica	44.38	0.00e+00	690.00
IUUC-Mmu-063674	Mus musculus	44.09	0.00e+00	690.00
IUUC-Mpu-066568	Mustela putorius furo	45.01	0.00e+00	701.00
IUUC-Mlu-067522	Myotis lucifugus	42.38	0.00e+00	650.00
IUUC-Nfi-068439	Neosartorya fischeri	36.11	2.00e-68	253.00
IUUC-Ncr-068903	Neurospora crassa	37.73	1.00e-66	246.00
IUUC-Nle-069505	Nomascus leucogenys	45.10	0.00e+00	696.00
IUUC-Opr-070570	Ochotona princeps	41.60	1.00e-176	611.00
IUUC-Ont-071527	Oreochromis niloticus	45.11	0.00e+00	689.00
IUUC-Oan-073240	Ornithorhynchus anatinus	60.76	2.00e-107	380.00
IUUC-Ocu-074922	Oryctolagus cuniculus	45.06	0.00e+00	697.00
IUUC-Ola-086833	Oryzias latipes	44.05	0.00e+00	632.00
IUUC-Oga-088261	Otolemur garnettii	45.01	0.00e+00	696.00
IUUC-Oar-090024	Ovis aries	44.83	0.00e+00	695.00
IUUC-Ptr-090455	Pan troglodytes	45.10	0.00e+00	696.00
IUUC-Pan-092509	Papio anubis	42.19	3.00e-166	577.00
IUUC-Psi-092974	Pelodiscus sinensis	43.96	0.00e+00	689.00
IUUC-Pma-094643	Petromyzon marinus	49.62	2.00e-180	624.00
IUUC-Ppa-095354	Physcomitrella patens	45.84	8.00e-102	363.00
IUUC-Pfo-096905	Poecilia formosa	44.56	0.00e+00	672.00
IUUC-Pab-097840	Pongo abelii	44.99	0.00e+00	681.00
IUUC-Pca-100869	Procavia capensis	44.05	0.00e+00	685.00
IUUC-Pva-103040	Pteropus vampyrus	61.31	6.00e-125	439.00
IUUC-Pgr-103315	Puccinia graminis	34.13	3.00e-67	248.00
IUUC-Ptt-103736	Puccinia triticina	34.79	4.00e-68	251.00
IUUC-Rno-105453	Rattus norvegicus	45.25	0.00e+00	687.00
IUUC-Sce-106306	Saccharomyces cerevisiae	37.59	1.00e-66	246.00
IUUC-Sha-107651	Sarcophilus harrisii	44.27	0.00e+00	689.00
IUUC-Spo-108271	Schizosaccharomyces pombe	34.55	2.00e-62	232.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	31.67	5.00e-57	214.00
IUUC-Smo-109329	Selaginella moellendorffii	51.29	2.00e-95	340.00
IUUC-Sar-113293	Sorex araneus	45.03	0.00e+00	699.00
IUUC-Ssc-115979	Sus scrofa	45.03	0.00e+00	700.00
IUUC-Tgu-116901	Taeniopygia guttata	44.42	0.00e+00	691.00
IUUC-Tru-118368	Takifugu rubripes	44.93	0.00e+00	675.00
IUUC-Tsy-119516	Tarsius syrichta	42.71	1.00e-179	621.00
IUUC-Tni-120143	Tetraodon nigroviridis	44.98	0.00e+00	677.00
IUUC-Tre-122108	Trichoderma reesei	36.69	8.00e-62	230.00
IUUC-Tvi-122644	Trichoderma virens	35.90	2.00e-63	236.00
IUUC-Tme-127004	Tuber melanosporum	30.76	3.00e-69	256.00
IUUC-Tbe-127484	Tupaia belangeri	36.20	9.00e-100	356.00
IUUC-Ttr-129078	Tursiops truncatus	44.71	0.00e+00	689.00
IUUC-Vda-129969	Verticillium dahliae	35.01	1.00e-68	253.00
IUUC-Vpa-130312	Vicugna pacos	39.23	2.00e-151	528.00
IUUC-Xtr-132881	Xenopus tropicalis	43.10	0.00e+00	674.00
IUUC-Xma-133122	Xiphophorus maculatus	44.64	0.00e+00	673.00
IUUC-Yli-134470	Yarrowia lipolytica	33.97	1.00e-54	206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence