iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050664

Ensembl Protein ID

ENSLACP00000010608.1

UniProt Accession

H3ALT7; H3ALT7_LATCH

Genbank Protein ID

ENSLACP00000010608

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01152180

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000009345.1	ENSLACT00000010687.1	ENSLACP00000010608.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-112	376.4	708	1071

Active Site

Position(s)	Description	Evidence
1039	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdg 85
           ++k +++v+fv+     E+g+d++Gv++efl++++k+++np l+lf+ +++d++ l+p+p+s++++ +hl+lFef+G++lgka+++g
   Q: 708  AMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKKVFNPALNLFKITSGDER-LYPSPTSYIHE-NHLQLFEFVGKMLGKAIYEG 792
           6899*******************************************9997766.59*******76.******************** PP
   S: 86   rlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtn 167
            ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + d+++lgl+l++  +e+++g+  ++eL+pgG++ipV n
   Q: 793  IVVDVPFASFFLSQLLGHhhsmfYSSIDELPSLDSEFYKNLTSIKRY-DGDVSDLGLTLSY--DEDVMGQLVCHELIPGGKTIPVSN 876
           ******************777776999********************.6799998777776..5999******************** PP
   S: 168  eNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevl 253
           eNk +Y++l++++r++++ik q++a+ +Gf+++i++e+l++F++ e++ li+G+ +eid+edlkk+t y gg++ ++++++w+w++l
   Q: 877  ENKISYIHLMAHFRMHTQIKDQTAALIRGFRSIINPEWLRMFSTPEVQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVVIWLWDIL 963
           ******************************************************9******************************** PP
   S: 254  .eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeYss 315
            ++f++eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk++   rlP+s+TCfn+LkLP+Ys+
   Q: 964  aNDFTAEERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSK 1050
           99*************************************************************9999******************** PP
   S: 316  keilkekLlyAieetkgFels 336
           k+il++kL+yAi++++gFels
   Q: 1051 KSILRDKLRYAISMNTGFELS 1071
           ******************985 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MFSTDQTLKA QFLDKARLAR EERKGHKERE KAAIQIQALI KRFLCRCRLQ KGIRKEVDDF 60
FEASETGLAK RNALSIFKIS RKFLFICNVK EDSARFEKLC RCILSSMEVE NEAKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTAGTA CAGACCAGAC ATTAAAGGCC CAGTTCCTTG ATAAAGCCCG CCTGGCACGT 60
GAAGAGAGGA AGGGGCATAA AGAAAGAGAG AAGGCAGCCA TCCAAATACA GGCGCTAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.68	1.00e-105	378.00
IUUC-Aml-002107	Ailuropoda melanoleuca	82.73	0.00e+00	1826.00
IUUC-Atr-003017	Amborella trichopoda	38.41	5.00e-110	392.00
IUUC-Apl-003328	Anas platyrhynchos	86.59	0.00e+00	1818.00
IUUC-Aly-005794	Arabidopsis lyrata	39.11	3.00e-108	386.00
IUUC-Ath-007269	Arabidopsis thaliana	39.46	6.00e-111	395.00
IUUC-Ago-007748	Ashbya gossypii	33.60	6.00e-67	249.00
IUUC-Acl-008158	Aspergillus clavatus	32.79	9.00e-61	229.00
IUUC-Afl-008398	Aspergillus flavus	33.13	4.00e-63	236.00
IUUC-Afu-008937	Aspergillus fumigatus	32.59	7.00e-62	232.00
IUUC-Ani-009252	Aspergillus nidulans	32.79	6.00e-68	252.00
IUUC-Ang-009773	Aspergillus niger	30.13	1.00e-64	241.00
IUUC-Aor-009940	Aspergillus oryzae	33.13	4.00e-63	236.00
IUUC-Ate-010395	Aspergillus terreus	33.33	4.00e-64	239.00
IUUC-Bgr-012269	Blumeria graminis	34.91	3.00e-61	228.00
IUUC-Bta-013547	Bos taurus	82.82	0.00e+00	1852.00
IUUC-Bci-013743	Botrytis cinerea	34.91	5.00e-72	266.00
IUUC-Bdi-014502	Brachypodium distachyon	39.15	3.00e-109	389.00
IUUC-Bol-015093	Brassica oleracea	40.00	4.00e-112	399.00
IUUC-Bra-016722	Brassica rapa	40.00	1.00e-112	401.00
IUUC-Cel-018447	Caenorhabditis elegans	38.85	0.00e+00	668.00
IUUC-Cja-019855	Callithrix jacchus	82.82	0.00e+00	1816.00
IUUC-Cfa-020066	Canis familiaris	82.14	0.00e+00	1806.00
IUUC-Cpo-021504	Cavia porcellus	82.17	0.00e+00	1842.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	36.14	4.00e-74	273.00
IUUC-Csa-023579	Chlorocebus sabaeus	82.54	0.00e+00	1820.00
IUUC-Cho-024430	Choloepus hoffmanni	72.10	0.00e+00	1308.00
IUUC-Cin-025750	Ciona intestinalis	46.53	0.00e+00	959.00
IUUC-Csv-026016	Ciona savignyi	47.33	0.00e+00	1014.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	35.42	1.00e-73	271.00
IUUC-Cme-027265	Cyanidioschyzon merolae	39.96	2.00e-88	320.00
IUUC-Dre-028271	Danio rerio	85.81	0.00e+00	1844.00
IUUC-Dno-029054	Dasypus novemcinctus	82.91	0.00e+00	1832.00
IUUC-Dor-030938	Dipodomys ordii	87.19	0.00e+00	1123.00
IUUC-Dse-031416	Dothistroma septosporum	34.83	1.00e-67	251.00
IUUC-Dme-031602	Drosophila melanogaster	48.63	0.00e+00	967.00
IUUC-Ete-033041	Echinops telfairi	67.73	0.00e+00	1211.00
IUUC-Eca-034411	Equus caballus	82.82	0.00e+00	1811.00
IUUC-Eeu-035201	Erinaceus europaeus	79.31	0.00e+00	767.00
IUUC-Fca-036594	Felis catus	81.61	0.00e+00	1791.00
IUUC-Fal-037317	Ficedula albicollis	83.42	0.00e+00	1851.00
IUUC-Fox-037788	Fusarium oxysporum	31.92	1.00e-75	278.00
IUUC-Fso-038088	Fusarium solani	34.10	2.00e-73	271.00
IUUC-Gmo-039412	Gadus morhua	82.83	0.00e+00	1828.00
IUUC-Ggr-039941	Gaeumannomyces graminis	35.83	1.00e-73	271.00
IUUC-Gga-040149	Gallus gallus	87.02	0.00e+00	1874.00
IUUC-Gac-042088	Gasterosteus aculeatus	85.09	0.00e+00	1906.00
IUUC-Gma-042728	Glycine max	40.14	9.00e-111	395.00
IUUC-Ggo-045279	Gorilla gorilla	82.45	0.00e+00	1817.00
IUUC-Hsa-045660	Homo sapiens	82.26	0.00e+00	1813.00
IUUC-Hvu-047770	Hordeum vulgare	36.91	6.00e-106	378.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	74.79	0.00e+00	855.00
IUUC-Kpa-049307	Komagataella pastoris	32.59	2.00e-64	240.00
IUUC-Lpe-050755	Leersia perrieri	37.63	1.00e-99	357.00
IUUC-Loc-052791	Lepisosteus oculatus	87.81	0.00e+00	1885.00
IUUC-Lma-053096	Leptosphaeria maculans	35.46	4.00e-69	256.00
IUUC-Laf-053902	Loxodonta africana	83.57	0.00e+00	1842.00
IUUC-Mcc-054730	Macaca mulatta	82.45	0.00e+00	1821.00
IUUC-Meu-056527	Macropus eugenii	77.63	0.00e+00	1655.00
IUUC-Mpo-057570	Magnaporthe poae	35.62	5.00e-71	263.00
IUUC-Mtr-057671	Medicago truncatula	39.61	6.00e-110	392.00
IUUC-Mga-059260	Meleagris gallopavo	86.58	0.00e+00	1870.00
IUUC-Mvi-060445	Microbotryum violaceum	33.67	2.00e-83	304.00
IUUC-Mmr-060804	Microcebus murinus	81.33	0.00e+00	1768.00
IUUC-Mdo-062575	Monodelphis domestica	81.44	0.00e+00	1756.00
IUUC-Mmu-063636	Mus musculus	81.05	0.00e+00	1758.00
IUUC-Mac-064989	Musa acuminata	39.72	2.00e-108	387.00
IUUC-Mpu-066677	Mustela putorius furo	81.55	0.00e+00	1699.00
IUUC-Mlu-067952	Myotis lucifugus	82.63	0.00e+00	1767.00
IUUC-Nfi-068280	Neosartorya fischeri	32.79	2.00e-62	234.00
IUUC-Ncr-068869	Neurospora crassa	32.30	2.00e-71	264.00
IUUC-Nle-069153	Nomascus leucogenys	82.54	0.00e+00	1815.00
IUUC-Opr-070554	Ochotona princeps	83.98	0.00e+00	1689.00
IUUC-Ont-071372	Oreochromis niloticus	86.18	0.00e+00	1884.00
IUUC-Oan-073327	Ornithorhynchus anatinus	69.57	0.00e+00	736.00
IUUC-Ocu-074183	Oryctolagus cuniculus	81.51	0.00e+00	1804.00
IUUC-Oba-075006	Oryza barthii	37.28	6.00e-109	389.00
IUUC-Obr-076320	Oryza brachyantha	39.17	5.00e-110	392.00
IUUC-Ogl-077093	Oryza glaberrima	39.17	7.00e-110	392.00
IUUC-Ogu-078947	Oryza glumaepatula	37.12	2.00e-109	390.00
IUUC-Oin-080058	Oryza indica	39.17	3.00e-109	389.00
IUUC-Olo-080475	Oryza longistaminata	37.28	1.00e-109	390.00
IUUC-Ome-081741	Oryza meridionalis	38.13	9.00e-102	365.00
IUUC-Oni-082385	Oryza nivara	37.12	2.00e-109	390.00
IUUC-Opu-083529	Oryza punctata	39.17	1.00e-109	391.00
IUUC-Oru-084554	Oryza rufipogon	34.91	2.00e-96	347.00
IUUC-Osa-085355	Oryza sativa	37.28	2.00e-109	390.00
IUUC-Ola-087337	Oryzias latipes	85.99	0.00e+00	1824.00
IUUC-Olu-087699	Ostreococcus lucimarinus	39.74	6.00e-77	280.00
IUUC-Oga-088342	Otolemur garnettii	82.18	0.00e+00	1748.00
IUUC-Oar-090234	Ovis aries	82.08	0.00e+00	1819.00
IUUC-Ptr-091661	Pan troglodytes	82.45	0.00e+00	1815.00
IUUC-Pan-092728	Papio anubis	82.28	0.00e+00	1816.00
IUUC-Psi-093251	Pelodiscus sinensis	86.31	0.00e+00	1731.00
IUUC-Pma-094195	Petromyzon marinus	70.38	0.00e+00	1481.00
IUUC-Ppa-095544	Physcomitrella patens	39.12	1.00e-109	391.00
IUUC-Pfo-097472	Poecilia formosa	86.55	0.00e+00	1890.00
IUUC-Pab-098570	Pongo abelii	82.45	0.00e+00	1816.00
IUUC-Pop-098928	Populus trichocarpa	33.86	7.00e-95	342.00
IUUC-Pca-100110	Procavia capensis	72.08	0.00e+00	1524.00
IUUC-Ppe-101281	Prunus persica	38.94	4.00e-106	379.00
IUUC-Pva-102887	Pteropus vampyrus	78.08	0.00e+00	1687.00
IUUC-Pte-104105	Pyrenophora teres	34.85	2.00e-68	254.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	34.85	1.00e-68	254.00
IUUC-Rno-106028	Rattus norvegicus	78.64	0.00e+00	1669.00
IUUC-Sce-106446	Saccharomyces cerevisiae	31.14	9.00e-55	208.00
IUUC-Sha-107331	Sarcophilus harrisii	82.67	0.00e+00	1791.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	39.12	1.00e-81	297.00
IUUC-Spo-108097	Schizosaccharomyces pombe	34.16	8.00e-82	298.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	30.77	3.00e-70	260.00
IUUC-Smo-109488	Selaginella moellendorffii	37.32	2.00e-107	383.00
IUUC-Sit-109811	Setaria italica	39.25	5.00e-108	385.00
IUUC-Sly-111362	Solanum lycopersicum	35.39	1.00e-100	360.00
IUUC-Sar-113287	Sorex araneus	68.69	4.00e-163	568.00
IUUC-Sbi-114433	Sorghum bicolor	39.57	5.00e-109	389.00
IUUC-Sre-115038	Sporisorium reilianum	40.00	1.00e-82	301.00
IUUC-Ssc-116103	Sus scrofa	83.38	0.00e+00	1815.00
IUUC-Tgu-117275	Taeniopygia guttata	86.27	0.00e+00	1857.00
IUUC-Tru-118681	Takifugu rubripes	84.59	0.00e+00	1896.00
IUUC-Tsy-118985	Tarsius syrichta	72.73	0.00e+00	837.00
IUUC-Tni-120850	Tetraodon nigroviridis	93.98	0.00e+00	800.00
IUUC-Tca-121770	Theobroma cacao	38.83	1.00e-110	394.00
IUUC-Tre-121892	Trichoderma reesei	35.91	1.00e-76	281.00
IUUC-Tvi-122354	Trichoderma virens	36.46	2.00e-79	291.00
IUUC-Tae-125466	Triticum aestivum	36.04	8.00e-106	378.00
IUUC-Tur-126086	Triticum urartu	39.86	4.00e-105	376.00
IUUC-Tme-127102	Tuber melanosporum	37.20	4.00e-79	290.00
IUUC-Tbe-127461	Tupaia belangeri	78.71	0.00e+00	1664.00
IUUC-Ttr-129269	Tursiops truncatus	82.35	0.00e+00	1790.00
IUUC-Uma-129343	Ustilago maydis	39.91	3.00e-85	310.00
IUUC-Vda-129748	Verticillium dahliae	33.82	6.00e-63	236.00
IUUC-Vpa-130523	Vicugna pacos	73.18	3.00e-113	402.00
IUUC-Vvi-131524	Vitis vinifera	39.32	1.00e-108	388.00
IUUC-Xtr-132146	Xenopus tropicalis	85.18	0.00e+00	1867.00
IUUC-Xma-133526	Xiphophorus maculatus	86.27	0.00e+00	1884.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence