iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pyt-104449

Ensembl Protein ID

EDU40964

UniProt Accession

B2VWG4; B2VWG4_PYRTR

Genbank Protein ID

EDU40964.1

Protein Name

E3 ubiquitin-protein ligase NEDD4

Genbank Nucleotide ID

DS231615

Gene Name

PTRG_01526

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PTRG_01526	EDU40964	EDU40964

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.20e-84	282.1	825	1205

Active Site

Position(s)	Description	Evidence
1173	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvg.....EegldlgGvtreflallskelqnpd..lglflysendketlqpnpdsglknp....................ehlklFeflGr 76
           lk+ ++++f +     E+g+d gGvt+efl+ ++++ + p+  + +f   end++ l+pnp++  +++                    e l+ +eflGr
   Q: 825  LKEPIQITFMDqfgaaEAGIDGGGVTKEFLTSVTNRAFMPTdyIDMF--VENDQHLLYPNPAALEEHKealrqaglrenspeyraqvtELLQRYEFLGR 921
           6778889999999999**********************999555666..788999999***99987779****************************** PP
   S: 77   llgkalqdgrlldlplsksfyklllgk............klsledleevdpelykslkeikenaesdieelgldltfs...vseei.......lgetke 153
           ++gk+l++g l+d++++++f+++   +            + +l+dl ++d+ely+ l ++k +   d+e+ +l++t++   v   +         ++ +
   Q: 922  IIGKCLYEGILVDVNFAPFFLRKWALTggagsapnesgyRPTLNDLRDLDEELYQGLHKLKTY-PGDVEDFSLNFTVTdtvV---VdhatspkKTKAIT 1016
           **********************9844444555665555589**********************.579999999999884430...25566766555666 PP
   S: 154  eeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketky.....kggytedspai 246
           +eLkp+G+n+pVtn+N+  Y++ ++ +rl+++   q++af +G++++i++++ls+F+++el++li+G+ ++idvedl+++t y      g+  +++p+i
   Q: 1017 KELKPDGSNTPVTNQNRLVYISYMARHRLQNQPYAQTTAFLRGLSTMIQPSWLSMFNQSELQTLISGTrTSIDVEDLRRNTIYggtyvIGDDGQEHPTI 1115
           77*******************************************************************************88555563444799**** PP
   S: 247  qwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           q +w+v++e+s++er+a L+FvT+++r+Pl Gf +l+pr f ir+++sd +rlPs +TC+n+LkLP Y  +++lkekLly + +++gF+ls
   Q: 1116 QILWKVMKEMSDDERRAVLKFVTSTPRAPLLGFGTLNPR-FSIRDAGSDqERLPSTSTCVNLLKLPMYRDEKTLKEKLLYSVFSGAGFDLS 1205
           *************************************99.9999988887**************************************985 PP

Organism

Pyrenophora triticirepentis

Protein Sequence
(Fasta)

MFTSFTGNTR RARQVNLGGK KTNPFGPPGS GAGSQAALDR AQQERAQRQR ERDTLNASKR 60
IQRVWRGHFA RRELADHIRG EWDKVEAPKG VLANTAYGSE EEALTQLQHL LRFASPRSED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCACCGCGG CCACCGGAGA CACGTAGAAT CCATTCGAAG GCAAGTGTGT GGTCGAATCA 60
TTCCTTGTAC AAGTCACGAC ATCCTGTGCA TCGTTCCTTC ACGCACGGGT AACACCCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	34.26	6.00e-82	297.00
IUUC-Aml-001355	Ailuropoda melanoleuca	34.44	3.00e-83	301.00
IUUC-Atr-003017	Amborella trichopoda	33.74	2.00e-80	292.00
IUUC-Apl-003731	Anas platyrhynchos	34.74	3.00e-85	308.00
IUUC-Aca-005248	Anolis carolinensis	35.27	2.00e-86	312.00
IUUC-Aly-005768	Arabidopsis lyrata	38.28	2.00e-80	292.00
IUUC-Ath-006576	Arabidopsis thaliana	38.28	4.00e-81	294.00
IUUC-Ago-007748	Ashbya gossypii	39.61	2.00e-82	298.00
IUUC-Acl-008158	Aspergillus clavatus	49.57	0.00e+00	993.00
IUUC-Afl-008398	Aspergillus flavus	50.12	0.00e+00	1013.00
IUUC-Afu-008937	Aspergillus fumigatus	49.65	0.00e+00	1013.00
IUUC-Ani-009252	Aspergillus nidulans	51.22	0.00e+00	1057.00
IUUC-Ang-009773	Aspergillus niger	50.51	0.00e+00	1004.00
IUUC-Aor-009940	Aspergillus oryzae	50.12	0.00e+00	1013.00
IUUC-Ate-010395	Aspergillus terreus	50.55	0.00e+00	1005.00
IUUC-Ame-010769	Astyanax mexicanus	36.21	4.00e-60	224.00
IUUC-Bgr-012269	Blumeria graminis	60.78	6.00e-163	565.00
IUUC-Bta-012841	Bos taurus	34.92	1.00e-84	306.00
IUUC-Bci-013743	Botrytis cinerea	42.71	0.00e+00	883.00
IUUC-Bdi-014123	Brachypodium distachyon	39.10	8.00e-83	300.00
IUUC-Bol-015390	Brassica oleracea	37.20	2.00e-75	276.00
IUUC-Bra-016853	Brassica rapa	38.28	5.00e-81	294.00
IUUC-Cel-018447	Caenorhabditis elegans	33.06	2.00e-57	216.00
IUUC-Cja-019743	Callithrix jacchus	34.56	1.00e-82	299.00
IUUC-Cfa-021031	Canis familiaris	34.67	1.00e-83	303.00
IUUC-Cpo-022401	Cavia porcellus	34.84	5.00e-84	304.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	35.85	5.00e-67	246.00
IUUC-Csa-024107	Chlorocebus sabaeus	34.32	2.00e-82	299.00
IUUC-Cho-024750	Choloepus hoffmanni	41.36	3.00e-75	275.00
IUUC-Cin-025750	Ciona intestinalis	32.18	2.00e-62	232.00
IUUC-Csv-026016	Ciona savignyi	34.08	6.00e-68	251.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	42.13	0.00e+00	834.00
IUUC-Cne-026841	Cryptococcus neoformans	34.12	1.00e-92	333.00
IUUC-Cme-027265	Cyanidioschyzon merolae	39.53	4.00e-82	298.00
IUUC-Dre-028196	Danio rerio	35.61	3.00e-86	311.00
IUUC-Dno-029024	Dasypus novemcinctus	35.02	8.00e-85	306.00
IUUC-Dor-030938	Dipodomys ordii	37.00	2.00e-68	253.00
IUUC-Dse-031416	Dothistroma septosporum	45.24	0.00e+00	879.00
IUUC-Dme-031946	Drosophila melanogaster	34.23	8.00e-77	280.00
IUUC-Ete-033041	Echinops telfairi	34.20	8.00e-48	184.00
IUUC-Eca-033828	Equus caballus	35.04	9.00e-84	303.00
IUUC-Eeu-035201	Erinaceus europaeus	35.06	6.00e-49	187.00
IUUC-Fca-035907	Felis catus	34.27	1.00e-83	303.00
IUUC-Fal-037389	Ficedula albicollis	34.57	8.00e-85	306.00
IUUC-Fox-037788	Fusarium oxysporum	46.42	0.00e+00	718.00
IUUC-Fso-038088	Fusarium solani	39.93	0.00e+00	717.00
IUUC-Gmo-039412	Gadus morhua	33.33	4.00e-68	251.00
IUUC-Ggr-039941	Gaeumannomyces graminis	39.82	0.00e+00	729.00
IUUC-Gga-040310	Gallus gallus	34.57	1.00e-84	306.00
IUUC-Gac-042088	Gasterosteus aculeatus	34.16	2.00e-70	258.00
IUUC-Gma-042819	Glycine max	37.77	5.00e-72	264.00
IUUC-Ggo-045031	Gorilla gorilla	34.49	5.00e-83	301.00
IUUC-Hsa-045880	Homo sapiens	34.49	4.00e-83	301.00
IUUC-Hvu-047770	Hordeum vulgare	39.70	2.00e-83	301.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	35.83	2.00e-68	250.00
IUUC-Kpa-049307	Komagataella pastoris	31.52	1.00e-82	299.00
IUUC-Lch-050664	Latimeria chalumnae	34.85	2.00e-70	258.00
IUUC-Lpe-050755	Leersia perrieri	37.42	3.00e-79	288.00
IUUC-Loc-052218	Lepisosteus oculatus	35.31	1.00e-84	306.00
IUUC-Lma-053096	Leptosphaeria maculans	78.08	0.00e+00	1770.00
IUUC-Laf-053902	Loxodonta africana	33.56	6.00e-75	274.00
IUUC-Mcc-055127	Macaca mulatta	34.49	5.00e-83	301.00
IUUC-Meu-056527	Macropus eugenii	38.99	2.00e-55	209.00
IUUC-Mor-057021	Magnaporthe oryzae	40.18	0.00e+00	771.00
IUUC-Mpo-057570	Magnaporthe poae	47.23	0.00e+00	673.00
IUUC-Mtr-058154	Medicago truncatula	39.40	6.00e-76	277.00
IUUC-Mla-059124	Melampsora laricipopulina	41.76	2.00e-98	351.00
IUUC-Mga-059581	Meleagris gallopavo	34.57	7.00e-85	307.00
IUUC-Mvi-060445	Microbotryum violaceum	39.19	5.00e-120	424.00
IUUC-Mmr-061360	Microcebus murinus	34.84	1.00e-83	303.00
IUUC-Mdo-062194	Monodelphis domestica	35.21	4.00e-85	308.00
IUUC-Mmu-064189	Mus musculus	34.67	3.00e-83	301.00
IUUC-Mac-065275	Musa acuminata	38.54	2.00e-83	301.00
IUUC-Mpu-066439	Mustela putorius furo	34.67	5.00e-84	304.00
IUUC-Mlu-068228	Myotis lucifugus	35.21	2.00e-84	305.00
IUUC-Nfi-068280	Neosartorya fischeri	49.57	0.00e+00	1011.00
IUUC-Ncr-068869	Neurospora crassa	47.56	0.00e+00	738.00
IUUC-Nle-069687	Nomascus leucogenys	34.03	2.00e-82	298.00
IUUC-Opr-070554	Ochotona princeps	33.05	4.00e-74	271.00
IUUC-Ont-071836	Oreochromis niloticus	34.49	8.00e-83	300.00
IUUC-Oan-072800	Ornithorhynchus anatinus	34.86	8.00e-85	306.00
IUUC-Ocu-074587	Oryctolagus cuniculus	34.84	3.00e-84	305.00
IUUC-Oba-075006	Oryza barthii	38.76	2.00e-83	302.00
IUUC-Obr-076133	Oryza brachyantha	38.76	5.00e-84	304.00
IUUC-Ogl-077003	Oryza glaberrima	38.76	2.00e-83	302.00
IUUC-Ogu-078947	Oryza glumaepatula	38.76	9.00e-84	303.00
IUUC-Oin-080058	Oryza indica	36.88	1.00e-80	293.00
IUUC-Olo-080475	Oryza longistaminata	38.76	9.00e-84	303.00
IUUC-Ome-081741	Oryza meridionalis	36.50	2.00e-75	275.00
IUUC-Oni-082385	Oryza nivara	38.76	8.00e-84	303.00
IUUC-Opu-083176	Oryza punctata	38.76	8.00e-84	303.00
IUUC-Oru-084554	Oryza rufipogon	36.44	4.00e-72	265.00
IUUC-Osa-085355	Oryza sativa	38.76	9.00e-84	303.00
IUUC-Ola-087209	Oryzias latipes	35.09	7.00e-84	303.00
IUUC-Olu-087699	Ostreococcus lucimarinus	39.42	1.00e-71	261.00
IUUC-Oga-088776	Otolemur garnettii	34.84	1.00e-83	303.00
IUUC-Oar-089441	Ovis aries	34.92	7.00e-85	307.00
IUUC-Ptr-091273	Pan troglodytes	34.49	5.00e-83	301.00
IUUC-Pan-091981	Papio anubis	34.49	5.00e-83	301.00
IUUC-Psi-093251	Pelodiscus sinensis	33.02	4.00e-64	238.00
IUUC-Pma-094738	Petromyzon marinus	31.19	6.00e-83	300.00
IUUC-Pno-095132	Phaeosphaeria nodorum	76.98	0.00e+00	1302.00
IUUC-Ppa-095544	Physcomitrella patens	38.24	9.00e-82	297.00
IUUC-Pfo-097511	Poecilia formosa	35.02	1.00e-84	306.00
IUUC-Pab-098570	Pongo abelii	33.39	3.00e-75	275.00
IUUC-Pop-098928	Populus trichocarpa	37.77	7.00e-72	263.00
IUUC-Pca-100987	Procavia capensis	40.69	1.00e-76	279.00
IUUC-Ppe-102040	Prunus persica	38.63	3.00e-72	265.00
IUUC-Pva-102887	Pteropus vampyrus	35.67	9.00e-73	266.00
IUUC-Pgr-103513	Puccinia graminis	33.11	4.00e-109	387.00
IUUC-Ptt-103967	Puccinia triticina	32.38	3.00e-97	348.00
IUUC-Pte-104105	Pyrenophora teres	96.85	0.00e+00	2236.00
IUUC-Rno-106028	Rattus norvegicus	30.52	2.00e-57	216.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.35	5.00e-82	297.00
IUUC-Sha-107108	Sarcophilus harrisii	33.22	6.00e-74	270.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	32.57	1.00e-96	346.00
IUUC-Spo-108097	Schizosaccharomyces pombe	35.39	1.00e-99	356.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	43.05	0.00e+00	875.00
IUUC-Smo-109007	Selaginella moellendorffii	37.90	2.00e-80	292.00
IUUC-Sit-110457	Setaria italica	40.26	2.00e-77	282.00
IUUC-Sly-111362	Solanum lycopersicum	39.61	2.00e-76	279.00
IUUC-Sbi-113882	Sorghum bicolor	38.97	2.00e-74	272.00
IUUC-Sre-115038	Sporisorium reilianum	44.80	2.00e-99	355.00
IUUC-Ssc-116103	Sus scrofa	33.73	1.00e-74	273.00
IUUC-Tgu-116729	Taeniopygia guttata	34.86	7.00e-86	310.00
IUUC-Tru-118068	Takifugu rubripes	35.27	3.00e-83	301.00
IUUC-Tsy-118942	Tarsius syrichta	43.73	2.00e-59	222.00
IUUC-Tni-120732	Tetraodon nigroviridis	34.57	7.00e-78	284.00
IUUC-Tca-121737	Theobroma cacao	40.13	8.00e-85	306.00
IUUC-Tre-121892	Trichoderma reesei	39.89	0.00e+00	753.00
IUUC-Tvi-122354	Trichoderma virens	39.50	0.00e+00	790.00
IUUC-Tae-125580	Triticum aestivum	39.48	4.00e-83	301.00
IUUC-Tur-126086	Triticum urartu	34.26	4.00e-82	298.00
IUUC-Tme-127102	Tuber melanosporum	48.82	0.00e+00	709.00
IUUC-Tbe-127351	Tupaia belangeri	32.49	5.00e-64	237.00
IUUC-Ttr-129061	Tursiops truncatus	40.45	2.00e-76	279.00
IUUC-Uma-129343	Ustilago maydis	36.78	9.00e-115	406.00
IUUC-Vda-129748	Verticillium dahliae	45.94	0.00e+00	685.00
IUUC-Vvi-131234	Vitis vinifera	39.14	3.00e-74	271.00
IUUC-Xtr-132094	Xenopus tropicalis	34.86	3.00e-83	301.00
IUUC-Xma-133923	Xiphophorus maculatus	35.37	1.00e-84	306.00
IUUC-Yli-134496	Yarrowia lipolytica	39.05	2.00e-95	342.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence