iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055390

Ensembl Protein ID

ENSMMUP00000016338.2

UniProt Accession

F7FKQ9; F7FKQ9_MACMU

Genbank Protein ID

ENSMMUP00000016338

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03014846

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000012442.3	ENSMMUT00000017446.3	ENSMMUP00000016338.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	3.40e-58	195.2	101	172

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           eeyrlll++lq+++++++++td+l+ +lse+l+++e+e+il++++tkg+m++ae+L+++L  ++ke+W+++++
   Q: 101  EEYRLLLKRLQPEFKTRIIPTDILS-DLSECLINQECEEILQICSTKGMMAGAEKLVECLlrSDKENWPKTLK 172
           9************************.********************************************985 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MTTEQRRSLL AFQDYIRKTL DPTYILSYMA PWFREEEVQY IQAEKNNKGP MEAATLFLKF 60
LLELQEEGWF RGFLDALDHA GYSGLYEAIE SWDFKKIEKL EEYRLLLKRL QPEFKTRIIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTACGG AGCAGCGGCG CAGCCTGCTA GCCTTCCAGG ATTATATCAG GAAGACCCTG 60
GACCCTACCT ACATCCTGAG CTACATGGCC CCCTGGTTTA GGGAGGGTGA GTGTCCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR003593--AAA+_ATPase
IPR031964--CARD_dom
IPR011545--DEAD/DEAH_box_helicase_dom
IPR011029--DEATH-like_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00270--DEAD
PF00271--Helicase_C
PF11648--RIG-I_C-RD

SMART

SM00382--AAA
SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	77.98	0.00e+00	1458.00
IUUC-Apl-003966	Anas platyrhynchos	53.00	0.00e+00	905.00
IUUC-Aca-004499	Anolis carolinensis	46.51	0.00e+00	807.00
IUUC-Ame-011950	Astyanax mexicanus	43.96	0.00e+00	698.00
IUUC-Bta-012489	Bos taurus	78.82	0.00e+00	1433.00
IUUC-Cel-018230	Caenorhabditis elegans	29.89	1.00e-72	268.00
IUUC-Cja-018716	Callithrix jacchus	92.76	0.00e+00	1729.00
IUUC-Cfa-020269	Canis familiaris	80.52	0.00e+00	1516.00
IUUC-Cpo-022507	Cavia porcellus	75.73	0.00e+00	1419.00
IUUC-Csa-024209	Chlorocebus sabaeus	98.49	0.00e+00	1826.00
IUUC-Cho-025104	Choloepus hoffmanni	74.37	0.00e+00	1193.00
IUUC-Cin-025792	Ciona intestinalis	31.61	2.00e-79	290.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	25.32	2.00e-22	102.00
IUUC-Dno-028954	Dasypus novemcinctus	77.90	0.00e+00	1416.00
IUUC-Eca-034039	Equus caballus	81.08	0.00e+00	1523.00
IUUC-Eeu-035009	Erinaceus europaeus	68.95	0.00e+00	920.00
IUUC-Fca-036169	Felis catus	81.42	0.00e+00	1537.00
IUUC-Fal-037579	Ficedula albicollis	54.25	0.00e+00	915.00
IUUC-Fso-038398	Fusarium solani	27.03	2.00e-25	111.00
IUUC-Ggo-045318	Gorilla gorilla	91.70	0.00e+00	1591.00
IUUC-Hsa-046671	Homo sapiens	95.78	0.00e+00	1753.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	78.76	0.00e+00	1442.00
IUUC-Lch-050461	Latimeria chalumnae	51.69	0.00e+00	882.00
IUUC-Loc-052582	Lepisosteus oculatus	48.39	0.00e+00	848.00
IUUC-Laf-054324	Loxodonta africana	77.94	0.00e+00	1427.00
IUUC-Meu-056365	Macropus eugenii	55.42	2.00e-178	619.00
IUUC-Mor-057000	Magnaporthe oryzae	28.26	6.40e-01	30.00
IUUC-Mpo-057328	Magnaporthe poae	22.22	5.20e-01	30.40
IUUC-Mvi-060497	Microbotryum violaceum	25.38	3.00e-23	105.00
IUUC-Mmr-061407	Microcebus murinus	84.02	0.00e+00	1593.00
IUUC-Mmu-063939	Mus musculus	76.22	0.00e+00	1412.00
IUUC-Mpu-066226	Mustela putorius furo	78.47	0.00e+00	1384.00
IUUC-Mlu-068092	Myotis lucifugus	79.59	0.00e+00	1445.00
IUUC-Nfi-068405	Neosartorya fischeri	24.53	4.00e-26	114.00
IUUC-Opr-070246	Ochotona princeps	68.53	0.00e+00	680.00
IUUC-Oan-072742	Ornithorhynchus anatinus	61.05	0.00e+00	971.00
IUUC-Ocu-073959	Oryctolagus cuniculus	75.59	0.00e+00	1428.00
IUUC-Oga-089173	Otolemur garnettii	83.48	0.00e+00	1549.00
IUUC-Oar-089369	Ovis aries	78.60	0.00e+00	1400.00
IUUC-Ptr-091032	Pan troglodytes	95.78	0.00e+00	1753.00
IUUC-Pan-092383	Papio anubis	98.92	0.00e+00	1829.00
IUUC-Psi-093432	Pelodiscus sinensis	55.71	0.00e+00	1044.00
IUUC-Pma-094367	Petromyzon marinus	42.29	4.00e-116	411.00
IUUC-Pab-098416	Pongo abelii	95.20	0.00e+00	1638.00
IUUC-Pca-101006	Procavia capensis	76.46	0.00e+00	629.00
IUUC-Pva-102966	Pteropus vampyrus	81.72	0.00e+00	1516.00
IUUC-Pgr-103529	Puccinia graminis	27.47	4.00e-30	127.00
IUUC-Rno-105059	Rattus norvegicus	76.18	0.00e+00	908.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	24.86	3.00e-04	42.00
IUUC-Sar-113202	Sorex araneus	67.49	0.00e+00	1027.00
IUUC-Ssc-116120	Sus scrofa	77.74	0.00e+00	1406.00
IUUC-Tgu-117314	Taeniopygia guttata	52.46	0.00e+00	928.00
IUUC-Tsy-119453	Tarsius syrichta	83.11	0.00e+00	888.00
IUUC-Tre-122194	Trichoderma reesei	26.49	1.00e-19	92.80
IUUC-Ttr-128421	Tursiops truncatus	75.77	0.00e+00	1186.00
IUUC-Vpa-130602	Vicugna pacos	76.85	0.00e+00	1364.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence