iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009165

Ensembl Protein ID

CADANIAP00003744

UniProt Accession

C8VGS5; C8VGS5_EMENI

Genbank Protein ID

CBF82055.1

Protein Name

Ubiquitin conjugating enzyme, putative (AFU_orthologue AFUA_6G14130)

Genbank Nucleotide ID

BN001305

Gene Name

ANIA_05351

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00003744	CADANIAT00003744	CADANIAP00003744

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.30e-39	133.4	10	158

Active Site

Position(s)	Description	Evidence
91	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdpp.egisakpvdesdltewevlilGped.tpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk..... 87
           l+++l+++++d+  +gis+++vd+ +++ewev+++  +d   Y gg+F+++++fp++YP  PPk+kf+ ++fhPn+y+nG+vC+sil+     
   Q: 10   LARQLQHMQSDKDlPGISCGLVDN-NVFEWEVMLMISDDvKLYGGGFFRARLSFPPEYPHMPPKMKFEPPLFHPNIYPNGEVCISILHppeed 101
           567888888776559*********.9*****99887665278*********************************************888899 PP
   S: 88   ......eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
                  +e+Wsp+++ e++lls++s+l++pn es++n+eaa+l++++++e+k++vr
   Q: 102  kygyesAAERWSPVQTPETILLSVISMLSSPNDESAANVEAARLWRDDPKEFKRRVR 158
           9999999************************************************98 PP

Organism

Aspergillus nidulans

Protein Sequence
(Fasta)

MATTPAGRML ARQLQHMQSD KDLPGISCGL VDNNVFEWEV MLMISDDVKL YGGGFFRARL 60
SFPPEYPHMP PKMKFEPPLF HPNIYPNGEV CISILHPPEE DKYGYESAAE RWSPVQTPET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTCGGGATA ACTCTTTACT CTCGCGCCAT TTGTCCTCCT TATTCTCCTC TTGTCATCTG 60
AATTTCGCTA TCTTCTAGCT CCTTTCCCCT CTCTCGCCTC TCTCCTGCCC AGCTCTTCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0061186--P:negative regulation of chromatin silencing at silent mating-type cassette
GO:0031939--P:negative regulation of chromatin silencing at telomere
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008329	Aspergillus clavatus	92.86	9.00e-93	330.00
IUUC-Afl-008660	Aspergillus flavus	92.90	1.00e-91	326.00
IUUC-Afu-008841	Aspergillus fumigatus	94.64	1.00e-86	310.00
IUUC-Ang-009536	Aspergillus niger	92.26	8.00e-93	330.00
IUUC-Aor-009951	Aspergillus oryzae	92.81	1.00e-90	323.00
IUUC-Ate-010276	Aspergillus terreus	94.64	4.00e-94	334.00
IUUC-Bgr-012044	Blumeria graminis	67.63	4.00e-65	238.00
IUUC-Bci-013814	Botrytis cinerea	57.47	9.00e-56	207.00
IUUC-Csv-026074	Ciona savignyi	57.45	2.00e-44	169.00
IUUC-Cgl-026748	Colletotrichum gloeosporioides	68.83	3.00e-60	222.00
IUUC-Dse-031230	Dothistroma septosporum	71.97	2.00e-65	239.00
IUUC-Dme-031951	Drosophila melanogaster	56.55	7.00e-48	181.00
IUUC-Fox-037989	Fusarium oxysporum	72.89	3.00e-69	251.00
IUUC-Fso-038227	Fusarium solani	68.21	2.00e-68	249.00
IUUC-Ggr-040064	Gaeumannomyces graminis	73.17	7.00e-67	244.00
IUUC-Lma-053320	Leptosphaeria maculans	83.44	2.00e-78	282.00
IUUC-Mor-057150	Magnaporthe oryzae	72.50	5.00e-64	234.00
IUUC-Mla-059165	Melampsora laricipopulina	50.59	2.00e-45	172.00
IUUC-Nfi-068431	Neosartorya fischeri	94.05	2.00e-86	309.00
IUUC-Ncr-068668	Neurospora crassa	65.70	6.00e-64	234.00
IUUC-Pno-094811	Phaeosphaeria nodorum	78.66	1.00e-77	280.00
IUUC-Pte-104183	Pyrenophora teres	83.22	2.00e-73	265.00
IUUC-Pyt-104551	Pyrenophora triticirepentis	82.17	6.00e-77	277.00
IUUC-Spo-108104	Schizosaccharomyces pombe	60.48	8.00e-55	204.00
IUUC-Ssl-108633	Sclerotinia sclerotiorum	61.93	5.00e-60	221.00
IUUC-Sre-114933	Sporisorium reilianum	52.33	2.00e-40	156.00
IUUC-Tru-118696	Takifugu rubripes	52.57	2.00e-46	176.00
IUUC-Tni-120869	Tetraodon nigroviridis	54.49	3.00e-47	179.00
IUUC-Tre-122197	Trichoderma reesei	72.29	2.00e-67	246.00
IUUC-Tvi-122456	Trichoderma virens	72.29	3.00e-68	248.00
IUUC-Tme-126974	Tuber melanosporum	70.62	2.00e-62	229.00
IUUC-Uma-129506	Ustilago maydis	53.49	2.00e-41	159.00
IUUC-Vda-129670	Verticillium dahliae	63.16	8.00e-61	224.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence