iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093670

Ensembl Protein ID

ENSPSIP00000017503.1

UniProt Accession

K7GB42; K7GB42_PELSI

Genbank Protein ID

ENSPSIP00000017503

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

AGCU01109883

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000015520.1	ENSPSIT00000017582.1	ENSPSIP00000017503.1
ENSPSIG00000015520.1	ENSPSIT00000017588.1	ENSPSIP00000017509.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.80e-93	312.8	146	489

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ +++k++ +   +p+ +l++++ +lf+e+++++++   p +ll+ +++ a+++ gyeqq
   Q: 146  GLINLGNTCFMNCIVQALTHTPLLRDFFLS-DRHKCEMQ---SPSSCLVCEMSTLFQEFYSGHRSPHIPYRLLHLVWTHARHLAGYEQQ 230
           9*****************************.99999975...78********************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl   ld l++++k                  ++ ++ +++++ +++i+++F g l+s+++c+ c+ vs++ +pf+d+sl++pg+
   Q: 231  DAHEFLIAALDVLHRHCKG----------------DDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGS 303
           *****************22................22335677899999**************************************** PP
   S: 180  eetkke....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
           ++   +                    +l+dcL+ ft++e+l ++ k++c+ c+++qe++k+l++kklP v ++hLkRf  +++ k r+k
   Q: 304  STPFWPlspgsdgsvvngeshvsgttTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRF--EHSAKLRRK 390
           *87777************************************************************************..5666899** PP
   S: 249  inkkvefpleLdlspfcts............peekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevlee 325
           i+++v+fpleLd++pf++s            p+++ ++++kY+L+avv+H+G+l+sGHY+++++++k++W+++dD  +t+ + ++vl  
   Q: 391  ITTYVSFPLELDMTPFMASskesrmngqyqqPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLD- 478
           *******************5555555555554445555**************************************************. PP
   S: 326  tgstaYvlfYkrr 338
             s++Y+lfY+++
   Q: 479  --SEGYLLFYHKQ 489
           ..********985 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MNRTQESKLC CAKSCICHMC GAHLNRLHSC LYCVFFGCFT KKHIHEHAKT KRHNLAIDLL 60
YGGIYCFMCQ DYIYDKDMEQ IAKEEQRKAW KLQAFTPTVV SHYQCTMTGI GEKYSTWEPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGAATCAT CAGTTTCACT GATCCCAGAA TTTGGAATTT GTCCCAAAGT AGATGAACAG 60
AACTCAGGAG AGCAAGCTAT GCTGTGTAGG TGGCTGTAAT GGTATATTTT AATTCATAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0000124--C:SAGA complex
GO:0010485--F:H4 histone acetyltransferase activity
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016578--P:histone deubiquitination
GO:0016574--P:histone ubiquitination
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000393	Aegilops tauschii	37.57	2.00e-64	240.00
IUUC-Aml-001343	Ailuropoda melanoleuca	90.63	0.00e+00	939.00
IUUC-Atr-002653	Amborella trichopoda	38.38	4.00e-96	345.00
IUUC-Apl-003433	Anas platyrhynchos	100.00	0.00e+00	1016.00
IUUC-Aca-005347	Anolis carolinensis	95.98	0.00e+00	1000.00
IUUC-Aly-006565	Arabidopsis lyrata	36.13	2.00e-70	259.00
IUUC-Ath-007536	Arabidopsis thaliana	36.13	3.00e-70	258.00
IUUC-Ago-007811	Ashbya gossypii	30.18	2.00e-51	196.00
IUUC-Acl-008124	Aspergillus clavatus	31.24	3.00e-57	215.00
IUUC-Afl-008464	Aspergillus flavus	32.33	2.00e-54	205.00
IUUC-Afu-008912	Aspergillus fumigatus	30.56	3.00e-54	205.00
IUUC-Ani-009168	Aspergillus nidulans	31.24	9.00e-57	214.00
IUUC-Ang-009694	Aspergillus niger	30.60	4.00e-55	208.00
IUUC-Aor-010035	Aspergillus oryzae	35.21	2.00e-38	152.00
IUUC-Ate-010382	Aspergillus terreus	31.63	3.00e-52	198.00
IUUC-Ame-011253	Astyanax mexicanus	85.36	0.00e+00	843.00
IUUC-Bgr-012150	Blumeria graminis	30.69	1.00e-47	184.00
IUUC-Bta-013303	Bos taurus	92.55	0.00e+00	944.00
IUUC-Bci-013604	Botrytis cinerea	31.92	7.00e-56	211.00
IUUC-Bdi-014171	Brachypodium distachyon	35.15	9.00e-77	280.00
IUUC-Bol-016509	Brassica oleracea	37.24	1.00e-73	271.00
IUUC-Bra-016962	Brassica rapa	35.80	3.00e-71	262.00
IUUC-Cja-019283	Callithrix jacchus	93.17	0.00e+00	862.00
IUUC-Cfa-021239	Canis familiaris	92.55	0.00e+00	947.00
IUUC-Cpo-022354	Cavia porcellus	92.06	0.00e+00	946.00
IUUC-Csa-023145	Chlorocebus sabaeus	92.46	0.00e+00	954.00
IUUC-Cho-024938	Choloepus hoffmanni	80.15	5.00e-61	228.00
IUUC-Cin-025109	Ciona intestinalis	55.41	2.00e-121	428.00
IUUC-Csv-026214	Ciona savignyi	55.64	4.00e-169	587.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	31.07	2.00e-53	203.00
IUUC-Cne-027085	Cryptococcus neoformans	32.24	3.00e-62	232.00
IUUC-Dre-027433	Danio rerio	93.37	0.00e+00	934.00
IUUC-Dno-030095	Dasypus novemcinctus	92.75	0.00e+00	950.00
IUUC-Dor-030832	Dipodomys ordii	86.08	5.00e-98	350.00
IUUC-Dse-031415	Dothistroma septosporum	31.11	2.00e-59	223.00
IUUC-Dme-032074	Drosophila melanogaster	51.78	2.00e-132	465.00
IUUC-Ete-033175	Echinops telfairi	72.13	1.00e-176	612.00
IUUC-Eca-033736	Equus caballus	92.34	0.00e+00	943.00
IUUC-Eeu-034814	Erinaceus europaeus	98.57	1.00e-122	433.00
IUUC-Fca-035861	Felis catus	92.96	0.00e+00	949.00
IUUC-Fal-037645	Ficedula albicollis	100.00	0.00e+00	1001.00
IUUC-Fox-038046	Fusarium oxysporum	31.10	2.00e-54	206.00
IUUC-Fso-038321	Fusarium solani	31.87	6.00e-54	204.00
IUUC-Gmo-038474	Gadus morhua	95.27	5.00e-173	600.00
IUUC-Ggr-040044	Gaeumannomyces graminis	31.14	9.00e-55	207.00
IUUC-Gga-040624	Gallus gallus	100.00	0.00e+00	1015.00
IUUC-Gac-042197	Gasterosteus aculeatus	88.02	0.00e+00	878.00
IUUC-Gma-042897	Glycine max	33.83	1.00e-80	293.00
IUUC-Ggo-044409	Gorilla gorilla	92.46	0.00e+00	956.00
IUUC-Hsa-046521	Homo sapiens	92.46	0.00e+00	955.00
IUUC-Hvu-047739	Hordeum vulgare	38.67	9.00e-70	256.00
IUUC-Itr-048375	Ictidomys tridecemlineatus	91.65	0.00e+00	946.00
IUUC-Kpa-049135	Komagataella pastoris	34.32	9.00e-67	247.00
IUUC-Lch-050537	Latimeria chalumnae	93.89	0.00e+00	963.00
IUUC-Lpe-050969	Leersia perrieri	38.37	2.00e-73	269.00
IUUC-Loc-052765	Lepisosteus oculatus	85.12	0.00e+00	858.00
IUUC-Lma-053105	Leptosphaeria maculans	33.85	2.00e-63	236.00
IUUC-Laf-053571	Loxodonta africana	93.58	0.00e+00	953.00
IUUC-Mcc-055166	Macaca mulatta	92.46	0.00e+00	954.00
IUUC-Mor-057103	Magnaporthe oryzae	31.07	7.00e-56	211.00
IUUC-Mpo-057621	Magnaporthe poae	31.57	1.00e-54	207.00
IUUC-Mtr-057894	Medicago truncatula	38.92	3.00e-84	305.00
IUUC-Mla-059185	Melampsora laricipopulina	33.15	6.00e-42	164.00
IUUC-Mga-059709	Meleagris gallopavo	100.00	0.00e+00	1016.00
IUUC-Mvi-060530	Microbotryum violaceum	33.78	3.00e-58	218.00
IUUC-Mmr-060988	Microcebus murinus	92.26	0.00e+00	954.00
IUUC-Mdo-063065	Monodelphis domestica	95.72	0.00e+00	975.00
IUUC-Mmu-063829	Mus musculus	91.65	0.00e+00	949.00
IUUC-Mac-065419	Musa acuminata	39.84	6.00e-72	264.00
IUUC-Mpu-066687	Mustela putorius furo	91.26	0.00e+00	942.00
IUUC-Mlu-067330	Myotis lucifugus	81.71	0.00e+00	842.00
IUUC-Nfi-068423	Neosartorya fischeri	30.56	3.00e-54	205.00
IUUC-Ncr-068809	Neurospora crassa	30.53	4.00e-56	212.00
IUUC-Nle-069261	Nomascus leucogenys	88.19	0.00e+00	899.00
IUUC-Opr-070469	Ochotona princeps	76.26	0.00e+00	676.00
IUUC-Ont-071961	Oreochromis niloticus	90.48	0.00e+00	907.00
IUUC-Oan-073565	Ornithorhynchus anatinus	92.59	0.00e+00	985.00
IUUC-Ocu-074435	Oryctolagus cuniculus	92.05	0.00e+00	924.00
IUUC-Oba-075688	Oryza barthii	35.48	2.00e-75	276.00
IUUC-Obr-076652	Oryza brachyantha	41.42	2.00e-74	272.00
IUUC-Ogl-077910	Oryza glaberrima	35.89	7.00e-80	291.00
IUUC-Ogu-078479	Oryza glumaepatula	35.89	7.00e-80	291.00
IUUC-Oin-079697	Oryza indica	39.41	1.00e-75	276.00
IUUC-Olo-080811	Oryza longistaminata	41.38	7.00e-53	200.00
IUUC-Ome-081706	Oryza meridionalis	35.89	2.00e-79	290.00
IUUC-Oni-083070	Oryza nivara	35.48	9.00e-80	290.00
IUUC-Opu-083605	Oryza punctata	39.89	2.00e-67	248.00
IUUC-Oru-084522	Oryza rufipogon	35.89	7.00e-80	291.00
IUUC-Osa-085351	Oryza sativa	39.36	2.00e-76	280.00
IUUC-Ola-086743	Oryzias latipes	86.09	0.00e+00	752.00
IUUC-Olu-087695	Ostreococcus lucimarinus	32.08	9.00e-51	193.00
IUUC-Oga-089131	Otolemur garnettii	92.07	0.00e+00	954.00
IUUC-Oar-089319	Ovis aries	92.55	0.00e+00	944.00
IUUC-Ptr-090783	Pan troglodytes	93.37	0.00e+00	953.00
IUUC-Pan-092927	Papio anubis	92.26	0.00e+00	953.00
IUUC-Pma-094323	Petromyzon marinus	68.87	0.00e+00	706.00
IUUC-Pno-095141	Phaeosphaeria nodorum	31.78	4.00e-54	205.00
IUUC-Ppa-095413	Physcomitrella patens	35.43	4.00e-81	295.00
IUUC-Pfo-096462	Poecilia formosa	92.81	0.00e+00	936.00
IUUC-Pab-097612	Pongo abelii	92.46	0.00e+00	956.00
IUUC-Pop-099558	Populus trichocarpa	37.19	5.00e-84	305.00
IUUC-Pca-100329	Procavia capensis	81.87	0.00e+00	840.00
IUUC-Ppe-102020	Prunus persica	37.38	3.00e-88	318.00
IUUC-Pva-102721	Pteropus vampyrus	77.60	0.00e+00	781.00
IUUC-Pgr-103657	Puccinia graminis	29.83	1.00e-37	150.00
IUUC-Pte-104340	Pyrenophora teres	33.72	7.00e-57	214.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	35.36	2.00e-64	239.00
IUUC-Rno-105247	Rattus norvegicus	91.65	0.00e+00	949.00
IUUC-Sce-106247	Saccharomyces cerevisiae	30.82	9.00e-51	194.00
IUUC-Sha-107538	Sarcophilus harrisii	97.24	6.00e-126	442.00
IUUC-Sja-107656	Schizosaccharomyces japonicus	34.23	3.00e-66	245.00
IUUC-Spo-108226	Schizosaccharomyces pombe	32.64	1.00e-59	223.00
IUUC-Ssl-108531	Sclerotinia sclerotiorum	31.36	1.00e-53	203.00
IUUC-Smo-109310	Selaginella moellendorffii	36.31	1.00e-85	310.00
IUUC-Sit-109716	Setaria italica	35.41	2.00e-79	289.00
IUUC-Sly-111077	Solanum lycopersicum	37.53	5.00e-77	281.00
IUUC-Stu-112203	Solanum tuberosum	38.26	1.00e-72	266.00
IUUC-Sar-113174	Sorex araneus	79.12	0.00e+00	757.00
IUUC-Sbi-114205	Sorghum bicolor	35.07	2.00e-80	293.00
IUUC-Sre-115195	Sporisorium reilianum	33.46	3.00e-30	126.00
IUUC-Ssc-115315	Sus scrofa	83.30	0.00e+00	862.00
IUUC-Tgu-116938	Taeniopygia guttata	96.89	0.00e+00	974.00
IUUC-Tru-117622	Takifugu rubripes	92.26	0.00e+00	946.00
IUUC-Tsy-119431	Tarsius syrichta	80.95	0.00e+00	796.00
IUUC-Tni-120119	Tetraodon nigroviridis	91.24	0.00e+00	934.00
IUUC-Tca-121154	Theobroma cacao	37.96	2.00e-87	316.00
IUUC-Tre-122139	Trichoderma reesei	31.50	3.00e-53	202.00
IUUC-Tvi-122599	Trichoderma virens	30.97	4.00e-54	205.00
IUUC-Tae-125608	Triticum aestivum	35.76	1.00e-87	317.00
IUUC-Tme-127115	Tuber melanosporum	37.34	5.00e-79	288.00
IUUC-Ttr-129006	Tursiops truncatus	82.12	0.00e+00	826.00
IUUC-Uma-129455	Ustilago maydis	33.58	1.00e-32	134.00
IUUC-Vda-129829	Verticillium dahliae	33.22	2.00e-35	142.00
IUUC-Vvi-131477	Vitis vinifera	37.50	3.00e-75	275.00
IUUC-Xtr-132444	Xenopus tropicalis	95.52	0.00e+00	989.00
IUUC-Xma-133514	Xiphophorus maculatus	92.46	0.00e+00	944.00
IUUC-Yli-134357	Yarrowia lipolytica	30.52	4.00e-48	185.00
IUUC-Zma-134945	Zea mays	35.15	2.00e-77	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence