iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006575

Ensembl Protein ID

AT3G12400.2

UniProt Accession

Q9LHG8; ELC_ARATH

Genbank Protein ID

BAB03147.1; AAG51025.1; AEE75193.1; AAL07132.1; AAM91713.1; AAM65318.1

Protein Name

Protein ELC; ESCRT-I complex subunit VPS23 homolog 1; Protein VACUOLAR PROTEIN SORTING 23A; Vacuolar protein-sorting-associated protein 23 homolog 1

Genbank Nucleotide ID

AP002047; AC069474; CP002686; AY056283; AY133779; AY087782

Gene Name

ELC; ELCH; VPS23A; At3g12400; T2E22.28

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G12400	AT3G12400.2	AT3G12400.2
AT3G12400	AT3G12400.3	AT3G12400.3
AT3G12400	AT3G12400.1	AT3G12400.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/UBC-like/UBD_UEV	UBD_UEV	17090720

Classification

Family	E-value	Score	Start	End
UBD/UBC-like/UBD_UEV	2.60e-61	206.5	18	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/UBC-like/UBD_UEV

   S: 1    AvsesslkkvpskykdkrltvrellnliesykslkpktasfvlnDgesreLlrltGtipvpergitynipiilwlletYPekPPfvsvkekidmntik 98
           A+s++ +++vp+++++k+l++++llnli+sy+sl+pktasf++nDg+s++Ll+++Gtip+p++g+tynip+i+wlle+YP++PP+v+v++++dm +ik
   Q: 18   ALSQRGPSSVPYEESNKWLIRQHLLNLISSYPSLEPKTASFMHNDGRSVNLLQADGTIPMPFHGVTYNIPVIIWLLESYPRHPPCVYVNPTADM-IIK 114
           899*******************************************************************************************.*** PP
   S: 99   ssnehvdpnGkialpvLhkWknpasnlvelvqelivllskeppklsrp 146
           ++++hv+p+G+++lp+L++W +p+snlv+lv++l+++++++pp +sr+
   Q: 115  RPHAHVTPSGLVSLPYLQNWVYPSSNLVDLVSDLSAAFARDPPLYSRR 162
           *********************************************996 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) Mediates the association to the ESCRT-0 complex. May control nuclear division through the microtubule cytoskeleton.

Protein Sequence
(Fasta)

MVPPPSNPQQ VQQFLSSALS QRGPSSVPYE ESNKWLIRQH LLNLISSYPS LEPKTASFMH 60
NDGRSVNLLQ ADGTIPMPFH GVTYNIPVII WLLESYPRHP PCVYVNPTAD MIIKRPHAHV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTGTCGTC GTCATCTTCA ATTTGGACTT CCAACGCCGA CACCGTTTAA CTCCGATGGT 60
TCCCCCGCCG TCTAATCCGC AGCAGGTTCA GCAGTTCCTC TCCTCTGCCC TCTCCCAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0967--Endosome
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR017916--SB_dom
IPR016135--UBQ-conjugating_enzyme/RWD
IPR008883--UEV_N

PROSITE

PS51312--SB
PS51322--UEV

Pfam

PF05743--UEV
PF09454--Vps23_core

Gene Ontology

GO:0005769--C:early endosome
GO:0000813--C:ESCRT I complex
GO:0005770--C:late endosome
GO:0043234--C:protein complex
GO:0043130--F:ubiquitin binding
GO:0051301--P:cell division
GO:0006464--P:cellular protein modification process
GO:0015031--P:protein transport
GO:0010091--P:trichome branching

KEGG

ath:AT3G12400

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001072	Aegilops tauschii	49.87	7.00e-90	323.00
IUUC-Aml-002415	Ailuropoda melanoleuca	41.13	1.00e-26	113.00
IUUC-Atr-002875	Amborella trichopoda	55.38	5.00e-114	403.00
IUUC-Apl-003473	Anas platyrhynchos	28.57	3.00e-36	145.00
IUUC-Aca-004573	Anolis carolinensis	39.67	9.00e-26	110.00
IUUC-Aly-006164	Arabidopsis lyrata	96.69	0.00e+00	635.00
IUUC-Acl-008218	Aspergillus clavatus	41.53	2.00e-22	99.80
IUUC-Afl-008597	Aspergillus flavus	43.33	2.00e-23	103.00
IUUC-Afu-009017	Aspergillus fumigatus	42.61	1.00e-21	97.10
IUUC-Ani-009468	Aspergillus nidulans	42.37	7.00e-20	91.30
IUUC-Ang-009755	Aspergillus niger	40.17	4.00e-21	95.90
IUUC-Aor-010072	Aspergillus oryzae	44.07	1.00e-23	103.00
IUUC-Ate-010400	Aspergillus terreus	43.22	2.00e-23	103.00
IUUC-Ame-011781	Astyanax mexicanus	35.17	2.00e-25	108.00
IUUC-Bgr-012136	Blumeria graminis	32.24	1.00e-17	84.00
IUUC-Bta-012557	Bos taurus	41.94	7.00e-27	114.00
IUUC-Bol-016308	Brassica oleracea	79.64	3.00e-167	581.00
IUUC-Bra-017605	Brassica rapa	79.90	8.00e-168	582.00
IUUC-Cel-018697	Caenorhabditis elegans	33.99	3.00e-22	99.00
IUUC-Cja-018963	Callithrix jacchus	30.00	7.00e-38	150.00
IUUC-Cfa-020472	Canis familiaris	40.32	5.00e-26	111.00
IUUC-Cpo-022001	Cavia porcellus	41.13	1.00e-26	113.00
IUUC-Cre-022918	Chlamydomonas reinhardtii	50.34	2.00e-41	162.00
IUUC-Csa-023959	Chlorocebus sabaeus	41.13	8.00e-27	114.00
IUUC-Cho-024389	Choloepus hoffmanni	39.39	1.00e-16	80.10
IUUC-Cin-025688	Ciona intestinalis	41.94	5.00e-26	111.00
IUUC-Cme-027280	Cyanidioschyzon merolae	40.46	1.00e-20	93.60
IUUC-Dre-027913	Danio rerio	38.71	1.00e-25	109.00
IUUC-Dno-029672	Dasypus novemcinctus	41.13	1.00e-26	113.00
IUUC-Dor-030175	Dipodomys ordii	37.78	2.00e-04	39.30
IUUC-Dse-031375	Dothistroma septosporum	37.93	1.00e-21	97.10
IUUC-Dme-031736	Drosophila melanogaster	35.76	7.00e-19	87.40
IUUC-Ete-032343	Echinops telfairi	41.13	5.00e-27	114.00
IUUC-Eca-033926	Equus caballus	40.32	3.00e-26	111.00
IUUC-Eeu-034940	Erinaceus europaeus	28.07	3.00e-35	142.00
IUUC-Fca-035491	Felis catus	40.32	5.00e-26	111.00
IUUC-Fal-037508	Ficedula albicollis	41.94	9.00e-28	117.00
IUUC-Fox-037937	Fusarium oxysporum	41.59	5.00e-21	95.10
IUUC-Fso-038091	Fusarium solani	43.97	8.00e-23	100.00
IUUC-Gmo-039427	Gadus morhua	38.10	3.00e-25	108.00
IUUC-Ggr-039724	Gaeumannomyces graminis	42.24	5.00e-22	98.60
IUUC-Gga-040998	Gallus gallus	31.69	1.00e-38	152.00
IUUC-Gac-041356	Gasterosteus aculeatus	37.10	2.00e-24	105.00
IUUC-Gma-043566	Glycine max	80.95	2.00e-72	265.00
IUUC-Ggo-044967	Gorilla gorilla	41.13	8.00e-27	114.00
IUUC-Hsa-046686	Homo sapiens	41.13	8.00e-27	114.00
IUUC-Hvu-047430	Hordeum vulgare	49.74	3.00e-89	321.00
IUUC-Itr-047929	Ictidomys tridecemlineatus	32.31	1.00e-10	59.30
IUUC-Kpa-049287	Komagataella pastoris	33.33	3.00e-15	75.90
IUUC-Lch-050597	Latimeria chalumnae	40.32	2.00e-26	112.00
IUUC-Loc-052399	Lepisosteus oculatus	38.71	1.00e-25	110.00
IUUC-Lma-053249	Leptosphaeria maculans	33.04	9.00e-13	68.20
IUUC-Laf-053766	Loxodonta africana	41.13	8.00e-27	114.00
IUUC-Mcc-055641	Macaca mulatta	41.13	8.00e-27	114.00
IUUC-Meu-055919	Macropus eugenii	42.11	8.00e-16	77.00
IUUC-Mor-056970	Magnaporthe oryzae	41.74	6.00e-21	95.10
IUUC-Mpo-057345	Magnaporthe poae	41.59	9.00e-20	90.90
IUUC-Mtr-058436	Medicago truncatula	58.87	8.00e-129	452.00
IUUC-Mla-059037	Melampsora laricipopulina	43.59	5.00e-24	105.00
IUUC-Mga-059263	Meleagris gallopavo	31.71	2.00e-38	152.00
IUUC-Mmr-060915	Microcebus murinus	40.32	5.00e-26	111.00
IUUC-Mdo-062449	Monodelphis domestica	39.52	2.00e-25	108.00
IUUC-Mmu-063151	Mus musculus	39.52	2.00e-25	108.00
IUUC-Mpu-066621	Mustela putorius furo	41.13	1.00e-26	113.00
IUUC-Mlu-067336	Myotis lucifugus	39.52	1.00e-25	109.00
IUUC-Nfi-068530	Neosartorya fischeri	42.61	6.00e-22	98.20
IUUC-Ncr-068785	Neurospora crassa	39.83	6.00e-21	95.10
IUUC-Nle-069972	Nomascus leucogenys	41.13	8.00e-27	114.00
IUUC-Opr-071150	Ochotona princeps	42.74	2.00e-26	112.00
IUUC-Ont-071366	Oreochromis niloticus	37.90	2.00e-25	108.00
IUUC-Oan-072829	Ornithorhynchus anatinus	45.45	8.00e-23	97.80
IUUC-Ocu-074351	Oryctolagus cuniculus	41.13	9.00e-27	113.00
IUUC-Obr-076135	Oryza brachyantha	49.87	2.00e-94	338.00
IUUC-Olo-080460	Oryza longistaminata	51.70	2.00e-36	144.00
IUUC-Ola-086920	Oryzias latipes	38.71	3.00e-25	107.00
IUUC-Olu-087610	Ostreococcus lucimarinus	29.52	2.00e-19	89.40
IUUC-Oga-088304	Otolemur garnettii	41.13	5.00e-27	114.00
IUUC-Oar-089734	Ovis aries	41.94	7.00e-27	114.00
IUUC-Ptr-091476	Pan troglodytes	41.13	8.00e-27	114.00
IUUC-Pan-092341	Papio anubis	41.13	8.00e-27	114.00
IUUC-Psi-093470	Pelodiscus sinensis	40.32	8.00e-27	114.00
IUUC-Pma-094143	Petromyzon marinus	41.41	5.00e-20	91.30
IUUC-Pno-095069	Phaeosphaeria nodorum	45.16	2.00e-14	73.60
IUUC-Ppa-095933	Physcomitrella patens	44.60	3.00e-93	334.00
IUUC-Pfo-096321	Poecilia formosa	38.71	2.00e-25	109.00
IUUC-Pab-098527	Pongo abelii	40.32	2.00e-26	112.00
IUUC-Pca-101044	Procavia capensis	40.65	3.00e-23	102.00
IUUC-Ppe-101458	Prunus persica	75.46	4.00e-74	271.00
IUUC-Pva-102591	Pteropus vampyrus	35.48	6.00e-19	88.20
IUUC-Pgr-103615	Puccinia graminis	35.67	1.00e-20	94.40
IUUC-Pte-104171	Pyrenophora teres	43.10	3.00e-21	95.90
IUUC-Pyt-104433	Pyrenophora triticirepentis	38.98	6.00e-07	48.10
IUUC-Rno-105957	Rattus norvegicus	39.52	2.00e-25	108.00
IUUC-Sha-107607	Sarcophilus harrisii	43.14	1.00e-23	102.00
IUUC-Sja-107877	Schizosaccharomyces japonicus	23.53	4.00e-03	35.40
IUUC-Sly-111373	Solanum lycopersicum	74.19	3.00e-61	228.00
IUUC-Stu-112844	Solanum tuberosum	58.93	1.00e-113	402.00
IUUC-Sar-113653	Sorex araneus	46.24	3.00e-22	98.60
IUUC-Sbi-114390	Sorghum bicolor	50.39	3.00e-93	334.00
IUUC-Sre-115200	Sporisorium reilianum	47.32	6.00e-24	105.00
IUUC-Ssc-115404	Sus scrofa	43.81	4.00e-22	95.90
IUUC-Tgu-117506	Taeniopygia guttata	41.94	1.00e-27	116.00
IUUC-Tru-118063	Takifugu rubripes	39.52	2.00e-25	109.00
IUUC-Tsy-118851	Tarsius syrichta	43.43	1.00e-20	93.20
IUUC-Tni-120010	Tetraodon nigroviridis	39.52	1.00e-25	109.00
IUUC-Tre-122040	Trichoderma reesei	38.93	4.00e-21	95.50
IUUC-Tvi-122660	Trichoderma virens	42.37	4.00e-22	99.00
IUUC-Tae-124561	Triticum aestivum	49.87	7.00e-90	323.00
IUUC-Tur-126651	Triticum urartu	59.21	2.00e-50	191.00
IUUC-Tbe-127894	Tupaia belangeri	28.18	1.00e-04	40.40
IUUC-Ttr-128264	Tursiops truncatus	28.07	4.00e-36	144.00
IUUC-Uma-129407	Ustilago maydis	46.43	6.00e-23	102.00
IUUC-Vda-130002	Verticillium dahliae	38.79	6.00e-16	78.20
IUUC-Vpa-130156	Vicugna pacos	41.13	2.00e-25	109.00
IUUC-Vvi-131479	Vitis vinifera	73.86	1.00e-69	256.00
IUUC-Xtr-132332	Xenopus tropicalis	44.86	6.00e-24	102.00
IUUC-Xma-133186	Xiphophorus maculatus	38.71	2.00e-25	108.00
IUUC-Yli-134500	Yarrowia lipolytica	30.88	2.00e-05	42.70
IUUC-Zma-135391	Zea mays	49.62	5.00e-92	330.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence