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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Cel-018637
UUCD1 version UUC-CaE-00407
Ensembl Protein ID R05G6.4
UniProt Accession Q21755; NOSIP_CAEEL
Genbank Protein ID CCD71554.1
Protein Name Nitric oxide synthase-interacting protein homolog
Genbank Nucleotide ID FO081426
Gene Name R05G6.4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00019898 R05G6.4 R05G6.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 1.70e-10 41.1 40 79
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk 41
           + e+++C+++l++ r+Pv++p+G+ +dr++I + +  ++k
   Q: 40   IKEFHCCSLTLQPCRNPVISPTGYIFDREAILENILAQKK 79
           78999**************************988876665 PP
   
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
 Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
Protein Sequence
(Fasta)
MTRHGKNSTA ASVYTYHERR RDAKASGYGT LHARLGADSI KEFHCCSLTL QPCRNPVISP 60
TGYIFDREAI LENILAQKKA YAKKLKEYEK QVAEESAAAK IAEGQAETFT KRTQFSAIES 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018637|E3,U-box|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGTTCACTCA TTAACATCTA AATTAATATA AACTGGCTGA AAAACGATTT TAATACAGAA 60
AATGACCCGA CATGGAAAAA ACTCAACGGC TGCTTCTGTA TACACTTACC ATGAACGTAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018637|E3,U-box|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD
Pfam

PF15906--zf-NOSIP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0016567--P:protein ubiquitination
GO:0050999--P:regulation of nitric-oxide synthase activity
KEGG cel:CELE_R05G6.4
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000769 Aegilops tauschii 26.83 3.00e-20 92.00
IUUC-Aml-002069 Ailuropoda melanoleuca 43.75 2.00e-68 251.00
IUUC-Atr-002661 Amborella trichopoda 27.09 4.00e-22 97.10
IUUC-Aca-004630 Anolis carolinensis 43.61 5.00e-67 246.00
IUUC-Aly-006316 Arabidopsis lyrata 25.73 5.00e-25 106.00
IUUC-Ath-007000 Arabidopsis thaliana 25.25 1.00e-24 105.00
IUUC-Acl-008175 Aspergillus clavatus 34.67 1.00e-05 43.10
IUUC-Afl-008440 Aspergillus flavus 35.90 5.00e-07 47.40
IUUC-Ani-009153 Aspergillus nidulans 32.89 1.00e-05 43.10
IUUC-Ang-009556 Aspergillus niger 35.90 6.00e-08 50.40
IUUC-Aor-009892 Aspergillus oryzae 36.00 6.00e-06 43.90
IUUC-Ame-011874 Astyanax mexicanus 42.68 1.00e-64 238.00
IUUC-Bgr-012090 Blumeria graminis 26.52 1.00e-08 52.80
IUUC-Bta-012956 Bos taurus 44.20 6.00e-69 252.00
IUUC-Bci-013897 Botrytis cinerea 46.05 2.00e-11 62.40
IUUC-Bdi-014968 Brachypodium distachyon 29.00 3.00e-29 120.00
IUUC-Bol-015578 Brassica oleracea 27.21 2.00e-27 115.00
IUUC-Bra-017234 Brassica rapa 27.21 2.00e-27 115.00
IUUC-Cja-019632 Callithrix jacchus 42.68 4.00e-68 249.00
IUUC-Cfa-020192 Canis familiaris 43.57 2.00e-68 251.00
IUUC-Cpo-021939 Cavia porcellus 42.77 3.00e-67 246.00
IUUC-Cre-023005 Chlamydomonas reinhardtii 33.55 5.00e-42 163.00
IUUC-Csa-023802 Chlorocebus sabaeus 43.60 2.00e-68 251.00
IUUC-Cho-024637 Choloepus hoffmanni 50.56 8.00e-22 95.50
IUUC-Cin-025180 Ciona intestinalis 40.13 5.00e-60 223.00
IUUC-Csv-026206 Ciona savignyi 46.31 1.00e-31 128.00
IUUC-Cgl-026696 Colletotrichum gloeosporioides 26.72 3.00e-16 77.80
IUUC-Cne-026827 Cryptococcus neoformans 27.02 9.00e-13 66.20
IUUC-Dre-028092 Danio rerio 42.64 6.00e-66 243.00
IUUC-Dno-029501 Dasypus novemcinctus 43.35 4.00e-62 230.00
IUUC-Dor-030542 Dipodomys ordii 43.96 6.00e-71 259.00
IUUC-Dse-031188 Dothistroma septosporum 25.26 4.00e-12 64.30
IUUC-Dme-031734 Drosophila melanogaster 42.54 1.00e-64 238.00
IUUC-Eca-033577 Equus caballus 44.27 3.00e-71 260.00
IUUC-Fca-035761 Felis catus 45.31 3.00e-71 260.00
IUUC-Fox-037703 Fusarium oxysporum 25.93 1.00e-13 68.90
IUUC-Fso-038208 Fusarium solani 28.08 1.00e-13 68.90
IUUC-Gmo-038523 Gadus morhua 42.93 2.00e-38 150.00
IUUC-Ggr-040087 Gaeumannomyces graminis 47.37 4.00e-11 60.80
IUUC-Gac-042621 Gasterosteus aculeatus 43.89 1.00e-68 251.00
IUUC-Gma-042698 Glycine max 27.76 3.00e-25 107.00
IUUC-Ggo-045357 Gorilla gorilla 44.03 6.00e-68 249.00
IUUC-Hsa-046195 Homo sapiens 44.03 6.00e-68 249.00
IUUC-Hvu-047174 Hordeum vulgare 29.10 1.00e-31 128.00
IUUC-Itr-048487 Ictidomys tridecemlineatus 44.03 3.00e-69 253.00
IUUC-Lch-050569 Latimeria chalumnae 45.31 1.00e-59 221.00
IUUC-Lpe-050992 Leersia perrieri 33.18 2.00e-21 95.10
IUUC-Loc-052522 Lepisosteus oculatus 42.54 4.00e-62 229.00
IUUC-Lma-053254 Leptosphaeria maculans 25.32 4.00e-12 64.30
IUUC-Laf-053397 Loxodonta africana 44.34 2.00e-69 254.00
IUUC-Mcc-054681 Macaca mulatta 43.29 3.00e-68 250.00
IUUC-Meu-056723 Macropus eugenii 44.62 4.00e-69 253.00
IUUC-Mor-056961 Magnaporthe oryzae 25.39 2.00e-13 68.60
IUUC-Mtr-058063 Medicago truncatula 28.09 3.00e-28 117.00
IUUC-Mla-059004 Melampsora laricipopulina 29.56 6.00e-22 96.70
IUUC-Mvi-060460 Microbotryum violaceum 27.36 5.00e-23 100.00
IUUC-Mmr-060847 Microcebus murinus 43.60 2.00e-68 251.00
IUUC-Mdo-062480 Monodelphis domestica 44.55 1.00e-70 258.00
IUUC-Mmu-063809 Mus musculus 44.03 9.00e-70 255.00
IUUC-Mac-064870 Musa acuminata 29.73 5.00e-27 113.00
IUUC-Mpu-066322 Mustela putorius furo 44.97 2.00e-70 257.00
IUUC-Mlu-067556 Myotis lucifugus 44.03 1.00e-68 251.00
IUUC-Ncr-068898 Neurospora crassa 46.05 3.00e-09 54.70
IUUC-Nle-070049 Nomascus leucogenys 43.29 4.00e-68 249.00
IUUC-Opr-070972 Ochotona princeps 44.38 2.00e-68 250.00
IUUC-Ont-071682 Oreochromis niloticus 43.99 4.00e-67 246.00
IUUC-Oan-073296 Ornithorhynchus anatinus 61.02 2.00e-20 90.10
IUUC-Ocu-074218 Oryctolagus cuniculus 44.41 9.00e-63 232.00
IUUC-Oba-075284 Oryza barthii 30.33 2.00e-32 130.00
IUUC-Obr-076651 Oryza brachyantha 30.10 2.00e-32 131.00
IUUC-Ogl-077899 Oryza glaberrima 30.33 2.00e-32 130.00
IUUC-Ogu-078477 Oryza glumaepatula 30.67 2.00e-32 131.00
IUUC-Oin-080011 Oryza indica 30.33 3.00e-32 130.00
IUUC-Olo-080545 Oryza longistaminata 31.14 5.00e-27 114.00
IUUC-Ome-081543 Oryza meridionalis 30.33 3.00e-32 130.00
IUUC-Oni-082955 Oryza nivara 30.33 3.00e-32 130.00
IUUC-Opu-083565 Oryza punctata 30.00 1.00e-31 129.00
IUUC-Oru-084474 Oryza rufipogon 30.33 3.00e-32 130.00
IUUC-Osa-085913 Oryza sativa 30.33 3.00e-32 130.00
IUUC-Ola-086851 Oryzias latipes 43.63 2.00e-71 260.00
IUUC-Olu-087724 Ostreococcus lucimarinus 41.27 4.00e-10 57.40
IUUC-Oga-087970 Otolemur garnettii 42.86 3.00e-67 247.00
IUUC-Oar-089756 Ovis aries 43.04 6.00e-66 242.00
IUUC-Ptr-091485 Pan troglodytes 42.07 3.00e-64 237.00
IUUC-Pan-091832 Papio anubis 43.29 3.00e-68 250.00
IUUC-Pma-094551 Petromyzon marinus 41.33 2.00e-60 224.00
IUUC-Pno-094830 Phaeosphaeria nodorum 24.45 3.00e-05 41.20
IUUC-Ppa-095255 Physcomitrella patens 28.33 5.00e-25 107.00
IUUC-Pfo-096373 Poecilia formosa 43.95 1.00e-68 251.00
IUUC-Pab-098247 Pongo abelii 44.03 8.00e-68 249.00
IUUC-Pop-099186 Populus trichocarpa 29.19 3.00e-27 114.00
IUUC-Pca-100677 Procavia capensis 41.10 2.00e-47 180.00
IUUC-Ppe-101403 Prunus persica 26.42 1.00e-24 105.00
IUUC-Pva-103000 Pteropus vampyrus 45.00 3.00e-71 260.00
IUUC-Pgr-103663 Puccinia graminis 29.63 4.00e-24 104.00
IUUC-Ptt-103712 Puccinia triticina 40.74 5.00e-07 46.60
IUUC-Pte-104287 Pyrenophora teres 25.70 2.00e-14 72.00
IUUC-Pyt-104579 Pyrenophora triticirepentis 24.38 1.00e-12 66.20
IUUC-Rno-106069 Rattus norvegicus 44.34 2.00e-70 257.00
IUUC-Sha-106553 Sarcophilus harrisii 44.38 4.00e-70 256.00
IUUC-Smo-108874 Selaginella moellendorffii 26.85 9.00e-29 119.00
IUUC-Sit-110307 Setaria italica 30.00 5.00e-30 123.00
IUUC-Sly-111094 Solanum lycopersicum 30.00 1.00e-26 112.00
IUUC-Stu-112363 Solanum tuberosum 30.00 2.00e-26 111.00
IUUC-Sar-113480 Sorex araneus 43.17 3.00e-64 237.00
IUUC-Sbi-113939 Sorghum bicolor 29.67 4.00e-29 120.00
IUUC-Ssc-115644 Sus scrofa 45.28 7.00e-71 259.00
IUUC-Tru-118781 Takifugu rubripes 43.35 2.00e-69 254.00
IUUC-Tni-119985 Tetraodon nigroviridis 64.41 5.00e-22 94.00
IUUC-Tca-121795 Theobroma cacao 27.18 5.00e-28 116.00
IUUC-Tre-122037 Trichoderma reesei 27.95 2.00e-11 62.00
IUUC-Tvi-122524 Trichoderma virens 30.28 1.00e-17 82.40
IUUC-Tae-122828 Triticum aestivum 29.10 1.00e-31 129.00
IUUC-Tur-126387 Triticum urartu 29.00 4.00e-25 107.00
IUUC-Tme-127111 Tuber melanosporum 39.47 1.00e-09 55.80
IUUC-Ttr-128227 Tursiops truncatus 44.65 9.00e-70 255.00
IUUC-Vda-129924 Verticillium dahliae 29.14 6.00e-20 90.10
IUUC-Vpa-130802 Vicugna pacos 56.45 4.00e-19 87.00
IUUC-Vvi-131105 Vitis vinifera 28.81 1.00e-24 105.00
IUUC-Xtr-132830 Xenopus tropicalis 40.25 4.00e-61 226.00
IUUC-Xma-133618 Xiphophorus maculatus 40.13 7.00e-60 222.00
IUUC-Zma-135389 Zea mays 30.00 1.00e-29 122.00
Created Date 25-Jun-2017

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