iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045628

UUCD1 version

UUC-GoG-00056

Ensembl Protein ID

ENSGGOP00000001245.2

UniProt Accession

G3QFZ9; G3QFZ9_GORGO

Protein Name

Uncharacterized protein

Gene Name

HLTF

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000001261.2	ENSGGOT00000001269.2	ENSGGOP00000001245.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-06	29.5	765	806

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           CaiCl+++   p+++ C Hvf++ C+ q      ++++++++CPlCr
   Q: 765  CAICLDSLTV-PVITHCAHVFCKPCIcQV----IQNEQPHAKCPLCR 806
           ********88.999************444....599**********8 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSWMFKRKNR DPVWKYLQTV QYGVQGNFPR LSYPTFFPRF EFQDVIPPDD FLTSDEELDS 60
VLFGSLRGHV VGLRYYTGVV NNNEMVALQR DPNNPYDKNA IKVNNVNGNQ VGHLKKELAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCTGGA TGTTCAAGAG GTGAAGGGGG CGGAGGGGGT GGGGCGCTTG GGCTAACGGC 60
CTGGAGGCGT CCCCAAATGA ACCTGACCTT CCCTGCGTTC CTCTGCGTTC CCTGGGCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR014905--HIRAN
IPR030065--HLTF
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00271--Helicase_C
PF08797--HIRAN
PF00176--SNF2_N

SMART

SM00487--DEXDc
SM00490--HELICc
SM00910--HIRAN
SM00184--RING

Gene Ontology

GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003723--F:RNA binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0006301--P:postreplication repair
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000167	Aegilops tauschii	38.41	6.00e-110	392.00
IUUC-Aml-001237	Ailuropoda melanoleuca	93.59	0.00e+00	1850.00
IUUC-Atr-003058	Amborella trichopoda	37.87	1.00e-108	387.00
IUUC-Aca-004994	Anolis carolinensis	65.76	0.00e+00	1246.00
IUUC-Aly-005898	Arabidopsis lyrata	41.85	2.00e-118	419.00
IUUC-Ath-007559	Arabidopsis thaliana	41.05	2.00e-119	423.00
IUUC-Ago-007997	Ashbya gossypii	33.95	1.00e-78	288.00
IUUC-Acl-008022	Aspergillus clavatus	30.33	5.00e-77	283.00
IUUC-Afl-008697	Aspergillus flavus	36.02	2.00e-85	310.00
IUUC-Afu-008767	Aspergillus fumigatus	35.83	6.00e-86	312.00
IUUC-Ani-009435	Aspergillus nidulans	34.92	1.00e-83	304.00
IUUC-Ang-009874	Aspergillus niger	34.36	6.00e-83	301.00
IUUC-Aor-010130	Aspergillus oryzae	37.24	8.00e-87	315.00
IUUC-Ate-010582	Aspergillus terreus	34.39	1.00e-78	288.00
IUUC-Ame-011743	Astyanax mexicanus	60.45	0.00e+00	658.00
IUUC-Bgr-012253	Blumeria graminis	32.33	3.00e-84	306.00
IUUC-Bta-013391	Bos taurus	90.93	0.00e+00	1833.00
IUUC-Bci-013956	Botrytis cinerea	34.97	4.00e-81	296.00
IUUC-Bdi-014267	Brachypodium distachyon	40.40	7.00e-117	414.00
IUUC-Bol-016075	Brassica oleracea	41.86	1.00e-121	430.00
IUUC-Bra-017057	Brassica rapa	42.30	2.00e-121	429.00
IUUC-Cja-019685	Callithrix jacchus	96.84	0.00e+00	2012.00
IUUC-Cfa-020485	Canis familiaris	93.20	0.00e+00	1836.00
IUUC-Cpo-021361	Cavia porcellus	87.48	0.00e+00	1061.00
IUUC-Cre-022824	Chlamydomonas reinhardtii	29.40	1.00e-62	235.00
IUUC-Csa-023894	Chlorocebus sabaeus	97.83	0.00e+00	1969.00
IUUC-Cho-024891	Choloepus hoffmanni	77.43	0.00e+00	734.00
IUUC-Csv-026168	Ciona savignyi	28.89	2.00e-51	197.00
IUUC-Cgl-026606	Colletotrichum gloeosporioides	33.28	3.00e-89	323.00
IUUC-Cne-026829	Cryptococcus neoformans	36.68	3.00e-93	336.00
IUUC-Cme-027110	Cyanidioschyzon merolae	34.27	5.00e-91	329.00
IUUC-Dre-027867	Danio rerio	63.06	0.00e+00	725.00
IUUC-Dno-029517	Dasypus novemcinctus	91.42	0.00e+00	1818.00
IUUC-Dor-030590	Dipodomys ordii	88.18	0.00e+00	734.00
IUUC-Dse-031471	Dothistroma septosporum	30.45	4.00e-78	286.00
IUUC-Dme-031815	Drosophila melanogaster	30.52	4.00e-54	206.00
IUUC-Ete-032421	Echinops telfairi	75.32	0.00e+00	985.00
IUUC-Eca-034058	Equus caballus	92.74	0.00e+00	1807.00
IUUC-Eeu-034597	Erinaceus europaeus	74.85	0.00e+00	1412.00
IUUC-Fca-035390	Felis catus	92.90	0.00e+00	1816.00
IUUC-Fox-038039	Fusarium oxysporum	33.83	6.00e-90	325.00
IUUC-Fso-038179	Fusarium solani	34.06	6.00e-88	319.00
IUUC-Gmo-038544	Gadus morhua	55.76	0.00e+00	664.00
IUUC-Ggr-039735	Gaeumannomyces graminis	31.84	1.00e-73	271.00
IUUC-Gga-040472	Gallus gallus	32.24	7.00e-38	152.00
IUUC-Gac-042401	Gasterosteus aculeatus	57.05	0.00e+00	701.00
IUUC-Gma-044315	Glycine max	37.55	1.00e-101	364.00
IUUC-Hsa-045930	Homo sapiens	98.92	0.00e+00	1986.00
IUUC-Hvu-047747	Hordeum vulgare	38.87	7.00e-110	391.00
IUUC-Itr-048493	Ictidomys tridecemlineatus	92.14	0.00e+00	1861.00
IUUC-Kpa-049087	Komagataella pastoris	34.09	6.00e-84	305.00
IUUC-Lch-050617	Latimeria chalumnae	61.06	0.00e+00	1120.00
IUUC-Lpe-051724	Leersia perrieri	42.30	2.00e-121	429.00
IUUC-Loc-052785	Lepisosteus oculatus	65.05	0.00e+00	774.00
IUUC-Lma-052956	Leptosphaeria maculans	30.63	5.00e-78	286.00
IUUC-Laf-054309	Loxodonta africana	89.66	0.00e+00	1733.00
IUUC-Mcc-055493	Macaca mulatta	97.44	0.00e+00	1955.00
IUUC-Meu-056270	Macropus eugenii	77.65	0.00e+00	920.00
IUUC-Mor-056943	Magnaporthe oryzae	36.16	2.00e-92	333.00
IUUC-Mpo-057407	Magnaporthe poae	32.67	4.00e-81	296.00
IUUC-Mtr-058172	Medicago truncatula	42.47	7.00e-116	411.00
IUUC-Mla-059170	Melampsora laricipopulina	32.64	9.00e-74	271.00
IUUC-Mga-059553	Meleagris gallopavo	31.58	2.00e-37	151.00
IUUC-Mvi-060365	Microbotryum violaceum	34.34	4.00e-84	306.00
IUUC-Mmr-061043	Microcebus murinus	90.63	0.00e+00	1746.00
IUUC-Mdo-062919	Monodelphis domestica	80.71	0.00e+00	1498.00
IUUC-Mmu-064338	Mus musculus	82.94	0.00e+00	1669.00
IUUC-Mac-065666	Musa acuminata	35.66	6.00e-90	325.00
IUUC-Mpu-066781	Mustela putorius furo	93.10	0.00e+00	1834.00
IUUC-Mlu-068076	Myotis lucifugus	90.84	0.00e+00	1812.00
IUUC-Nfi-068386	Neosartorya fischeri	35.47	3.00e-83	303.00
IUUC-Ncr-068858	Neurospora crassa	37.22	5.00e-90	325.00
IUUC-Nle-069947	Nomascus leucogenys	98.42	0.00e+00	1980.00
IUUC-Opr-070388	Ochotona princeps	84.70	0.00e+00	1143.00
IUUC-Ont-071782	Oreochromis niloticus	61.08	0.00e+00	667.00
IUUC-Oan-073331	Ornithorhynchus anatinus	80.67	0.00e+00	1381.00
IUUC-Ocu-074705	Oryctolagus cuniculus	91.72	0.00e+00	1769.00
IUUC-Oba-075881	Oryza barthii	41.71	6.00e-120	425.00
IUUC-Obr-076344	Oryza brachyantha	41.67	1.00e-115	410.00
IUUC-Ogl-076957	Oryza glaberrima	41.71	6.00e-120	425.00
IUUC-Ogu-078648	Oryza glumaepatula	41.60	4.00e-115	409.00
IUUC-Oin-079449	Oryza indica	41.71	1.00e-115	410.00
IUUC-Olo-080721	Oryza longistaminata	41.53	1.00e-115	410.00
IUUC-Ome-081579	Oryza meridionalis	41.33	1.00e-115	410.00
IUUC-Oni-083054	Oryza nivara	41.71	1.00e-115	410.00
IUUC-Opu-083706	Oryza punctata	41.80	3.00e-116	412.00
IUUC-Oru-085259	Oryza rufipogon	41.71	9.00e-116	411.00
IUUC-Osa-085568	Oryza sativa	42.03	3.00e-102	366.00
IUUC-Ola-086830	Oryzias latipes	54.68	2.00e-178	619.00
IUUC-Olu-087669	Ostreococcus lucimarinus	30.16	9.00e-60	225.00
IUUC-Oga-088120	Otolemur garnettii	86.85	0.00e+00	1640.00
IUUC-Oar-089293	Ovis aries	90.94	0.00e+00	1845.00
IUUC-Ptr-091418	Pan troglodytes	98.92	0.00e+00	1989.00
IUUC-Pan-092579	Papio anubis	97.83	0.00e+00	1502.00
IUUC-Psi-093626	Pelodiscus sinensis	71.00	0.00e+00	1228.00
IUUC-Pno-094841	Phaeosphaeria nodorum	38.27	1.00e-86	315.00
IUUC-Ppa-095291	Physcomitrella patens	46.70	1.00e-143	504.00
IUUC-Pfo-096540	Poecilia formosa	56.45	0.00e+00	686.00
IUUC-Pab-098010	Pongo abelii	98.72	0.00e+00	1980.00
IUUC-Pop-099320	Populus trichocarpa	37.86	5.00e-108	385.00
IUUC-Pca-100648	Procavia capensis	78.01	0.00e+00	1509.00
IUUC-Ppe-102077	Prunus persica	42.31	5.00e-102	365.00
IUUC-Pva-102896	Pteropus vampyrus	89.42	0.00e+00	885.00
IUUC-Pgr-103403	Puccinia graminis	31.46	5.00e-74	273.00
IUUC-Ptt-103966	Puccinia triticina	32.04	3.00e-73	270.00
IUUC-Pte-104242	Pyrenophora teres	33.00	5.00e-82	299.00
IUUC-Pyt-104728	Pyrenophora triticirepentis	33.11	6.00e-81	295.00
IUUC-Rno-106130	Rattus norvegicus	82.54	0.00e+00	1670.00
IUUC-Sce-106396	Saccharomyces cerevisiae	32.29	5.00e-74	273.00
IUUC-Sha-107221	Sarcophilus harrisii	81.68	0.00e+00	1522.00
IUUC-Sja-107985	Schizosaccharomyces japonicus	34.19	4.00e-88	319.00
IUUC-Spo-108026	Schizosaccharomyces pombe	31.37	4.00e-83	303.00
IUUC-Ssl-108388	Sclerotinia sclerotiorum	35.51	2.00e-88	321.00
IUUC-Smo-109629	Selaginella moellendorffii	44.22	1.00e-131	464.00
IUUC-Sit-109770	Setaria italica	42.04	3.00e-119	422.00
IUUC-Sly-111031	Solanum lycopersicum	37.28	1.00e-108	387.00
IUUC-Stu-112600	Solanum tuberosum	37.57	9.00e-109	388.00
IUUC-Sar-113719	Sorex araneus	91.34	0.00e+00	1704.00
IUUC-Sbi-113927	Sorghum bicolor	37.36	4.00e-104	372.00
IUUC-Sre-114938	Sporisorium reilianum	30.22	2.00e-75	277.00
IUUC-Ssc-116186	Sus scrofa	93.29	0.00e+00	1897.00
IUUC-Tru-117768	Takifugu rubripes	51.35	0.00e+00	932.00
IUUC-Tsy-118957	Tarsius syrichta	85.12	0.00e+00	1656.00
IUUC-Tni-120618	Tetraodon nigroviridis	52.13	0.00e+00	978.00
IUUC-Tca-121146	Theobroma cacao	36.42	4.00e-110	392.00
IUUC-Tre-121896	Trichoderma reesei	34.10	1.00e-94	341.00
IUUC-Tvi-122597	Trichoderma virens	34.23	7.00e-91	328.00
IUUC-Tae-123773	Triticum aestivum	41.83	5.00e-109	389.00
IUUC-Tur-125999	Triticum urartu	39.05	2.00e-109	390.00
IUUC-Tme-126953	Tuber melanosporum	33.75	2.00e-89	324.00
IUUC-Tbe-127612	Tupaia belangeri	84.34	0.00e+00	816.00
IUUC-Ttr-128243	Tursiops truncatus	88.33	0.00e+00	1361.00
IUUC-Uma-129441	Ustilago maydis	30.23	7.00e-76	279.00
IUUC-Vda-129933	Verticillium dahliae	37.02	1.00e-83	304.00
IUUC-Vpa-130672	Vicugna pacos	92.67	0.00e+00	1722.00
IUUC-Vvi-131204	Vitis vinifera	42.83	4.00e-126	445.00
IUUC-Xtr-132730	Xenopus tropicalis	61.85	0.00e+00	1249.00
IUUC-Xma-133384	Xiphophorus maculatus	52.45	0.00e+00	967.00
IUUC-Yli-134350	Yarrowia lipolytica	31.93	1.00e-74	274.00
IUUC-Zma-134966	Zea mays	42.28	1.00e-125	444.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence