iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098422

Ensembl Protein ID

ENSPPYP00000022747.2

UniProt Accession

H2PVJ8; H2PVJ8_PONAB

Genbank Protein ID

ENSPPYP00000022747

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01232358

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000020320.2	ENSPPYT00000023709.2	ENSPPYP00000022747.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	97.64	0.00e+00	2247.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MTSTGQDSTT TRQRRSRQNP QSPPQDSSVT SKRNIKKGAV PRSIPNLAEV KKKGKMKKLG 60
QAMEEDLIVG LQGMDLNIEA EALAGTGLVL DEQLNEFHCL WDDSFPEGPE RLHAIKEQLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGTGTGGC TCGCGCGAGG GGCGCGGCCT TGAGGAACGG TCCCCTCTGG AGGCGGGATC 60
TGGGCGGGCA GTCGAGAGAC CAGGCCCAAT GGAAAAGAAA GGCCCGGGCG CTCGCGTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	41.80	8.00e-72	264.00
IUUC-Aml-002087	Ailuropoda melanoleuca	80.07	0.00e+00	1831.00
IUUC-Atr-002745	Amborella trichopoda	38.48	5.00e-74	271.00
IUUC-Aca-004303	Anolis carolinensis	50.79	0.00e+00	1126.00
IUUC-Aly-006432	Arabidopsis lyrata	41.49	2.00e-71	263.00
IUUC-Ath-007355	Arabidopsis thaliana	42.31	3.00e-75	276.00
IUUC-Ago-007972	Ashbya gossypii	37.72	9.00e-70	258.00
IUUC-Acl-008187	Aspergillus clavatus	39.42	4.00e-77	282.00
IUUC-Afl-008399	Aspergillus flavus	41.41	1.00e-39	157.00
IUUC-Afu-008954	Aspergillus fumigatus	35.69	2.00e-64	239.00
IUUC-Ani-009142	Aspergillus nidulans	39.39	1.00e-71	264.00
IUUC-Ang-009522	Aspergillus niger	37.09	3.00e-44	173.00
IUUC-Aor-010069	Aspergillus oryzae	37.67	5.00e-68	252.00
IUUC-Ate-010291	Aspergillus terreus	39.30	6.00e-77	282.00
IUUC-Ame-010780	Astyanax mexicanus	50.00	0.00e+00	744.00
IUUC-Bta-013052	Bos taurus	71.96	0.00e+00	1599.00
IUUC-Bci-013789	Botrytis cinerea	40.05	2.00e-69	256.00
IUUC-Bdi-014007	Brachypodium distachyon	41.90	2.00e-78	286.00
IUUC-Bol-015468	Brassica oleracea	43.72	3.00e-74	273.00
IUUC-Bra-016680	Brassica rapa	43.72	2.00e-74	273.00
IUUC-Cel-018220	Caenorhabditis elegans	37.83	4.00e-135	475.00
IUUC-Cja-019473	Callithrix jacchus	90.66	0.00e+00	2068.00
IUUC-Cfa-020263	Canis familiaris	84.01	0.00e+00	1523.00
IUUC-Cpo-021691	Cavia porcellus	78.12	0.00e+00	1779.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	56.28	7.00e-51	193.00
IUUC-Csa-024223	Chlorocebus sabaeus	96.63	0.00e+00	2240.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	41.55	8.00e-68	251.00
IUUC-Cne-026978	Cryptococcus neoformans	45.67	1.00e-77	284.00
IUUC-Dre-028820	Danio rerio	56.61	0.00e+00	863.00
IUUC-Dno-029160	Dasypus novemcinctus	69.22	0.00e+00	1532.00
IUUC-Dor-030859	Dipodomys ordii	71.00	0.00e+00	1615.00
IUUC-Dse-031186	Dothistroma septosporum	37.14	4.00e-70	259.00
IUUC-Dme-031963	Drosophila melanogaster	44.21	0.00e+00	644.00
IUUC-Ete-032279	Echinops telfairi	65.00	6.00e-142	498.00
IUUC-Eca-033842	Equus caballus	82.07	0.00e+00	1897.00
IUUC-Eeu-034487	Erinaceus europaeus	76.53	8.00e-153	534.00
IUUC-Fca-036430	Felis catus	74.40	0.00e+00	1624.00
IUUC-Fox-038067	Fusarium oxysporum	36.20	4.00e-66	246.00
IUUC-Fso-038263	Fusarium solani	37.63	3.00e-68	253.00
IUUC-Ggr-040062	Gaeumannomyces graminis	42.45	2.00e-67	250.00
IUUC-Gma-043738	Glycine max	48.91	1.00e-74	273.00
IUUC-Ggo-045022	Gorilla gorilla	97.56	0.00e+00	2243.00
IUUC-Hsa-046904	Homo sapiens	97.64	0.00e+00	2247.00
IUUC-Hvu-047285	Hordeum vulgare	42.11	6.00e-75	274.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	79.00	0.00e+00	1805.00
IUUC-Kpa-049281	Komagataella pastoris	39.07	1.00e-72	268.00
IUUC-Lch-050330	Latimeria chalumnae	45.85	0.00e+00	914.00
IUUC-Lpe-051214	Leersia perrieri	42.98	6.00e-82	298.00
IUUC-Lma-053263	Leptosphaeria maculans	40.91	4.00e-81	296.00
IUUC-Laf-053386	Loxodonta africana	78.21	0.00e+00	1421.00
IUUC-Mcc-055530	Macaca mulatta	96.63	0.00e+00	2224.00
IUUC-Meu-056442	Macropus eugenii	67.01	0.00e+00	919.00
IUUC-Mor-057095	Magnaporthe oryzae	39.26	3.00e-70	259.00
IUUC-Mpo-057389	Magnaporthe poae	42.17	2.00e-67	250.00
IUUC-Mtr-058463	Medicago truncatula	41.01	2.00e-78	286.00
IUUC-Mla-059143	Melampsora laricipopulina	42.57	5.00e-79	288.00
IUUC-Mmr-060637	Microcebus murinus	86.52	0.00e+00	2031.00
IUUC-Mdo-062198	Monodelphis domestica	66.34	0.00e+00	1017.00
IUUC-Mmu-063346	Mus musculus	73.42	0.00e+00	1682.00
IUUC-Mac-064630	Musa acuminata	44.04	2.00e-73	270.00
IUUC-Mpu-065884	Mustela putorius furo	78.11	0.00e+00	1791.00
IUUC-Mlu-068117	Myotis lucifugus	77.28	0.00e+00	1736.00
IUUC-Nfi-068404	Neosartorya fischeri	38.48	3.00e-75	276.00
IUUC-Ncr-068672	Neurospora crassa	42.69	6.00e-68	252.00
IUUC-Nle-069868	Nomascus leucogenys	98.43	0.00e+00	785.00
IUUC-Opr-071074	Ochotona princeps	70.49	0.00e+00	1095.00
IUUC-Ont-072246	Oreochromis niloticus	44.74	0.00e+00	911.00
IUUC-Oan-072911	Ornithorhynchus anatinus	66.53	4.00e-96	346.00
IUUC-Ocu-074627	Oryctolagus cuniculus	77.16	0.00e+00	1793.00
IUUC-Oba-075489	Oryza barthii	44.75	2.00e-78	286.00
IUUC-Obr-076150	Oryza brachyantha	42.46	5.00e-81	295.00
IUUC-Ogl-077437	Oryza glaberrima	42.58	9.00e-81	294.00
IUUC-Ogu-078370	Oryza glumaepatula	42.58	2.00e-81	296.00
IUUC-Oin-079210	Oryza indica	42.30	3.00e-81	296.00
IUUC-Olo-080971	Oryza longistaminata	46.40	4.00e-71	262.00
IUUC-Oni-082031	Oryza nivara	42.30	5.00e-81	295.00
IUUC-Opu-083471	Oryza punctata	44.44	1.00e-78	287.00
IUUC-Oru-084755	Oryza rufipogon	42.58	2.00e-81	296.00
IUUC-Osa-085447	Oryza sativa	42.58	3.00e-81	296.00
IUUC-Oga-089155	Otolemur garnettii	84.27	0.00e+00	1939.00
IUUC-Oar-089620	Ovis aries	72.29	0.00e+00	1600.00
IUUC-Ptr-090812	Pan troglodytes	96.58	0.00e+00	1333.00
IUUC-Pan-092340	Papio anubis	96.80	0.00e+00	2229.00
IUUC-Pma-094386	Petromyzon marinus	53.12	0.00e+00	775.00
IUUC-Pno-095131	Phaeosphaeria nodorum	47.35	6.00e-67	248.00
IUUC-Ppa-095550	Physcomitrella patens	47.88	2.00e-77	283.00
IUUC-Pfo-096110	Poecilia formosa	51.85	0.00e+00	676.00
IUUC-Pop-099174	Populus trichocarpa	38.94	2.00e-74	273.00
IUUC-Pca-100833	Procavia capensis	75.76	0.00e+00	1338.00
IUUC-Ppe-101644	Prunus persica	43.23	7.00e-76	278.00
IUUC-Pva-102410	Pteropus vampyrus	72.88	0.00e+00	1633.00
IUUC-Ptt-103841	Puccinia triticina	37.06	2.00e-69	256.00
IUUC-Pte-104383	Pyrenophora teres	40.53	7.00e-78	285.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	43.58	4.00e-75	275.00
IUUC-Rno-105131	Rattus norvegicus	71.31	0.00e+00	1618.00
IUUC-Sce-106274	Saccharomyces cerevisiae	34.70	8.00e-71	261.00
IUUC-Sha-106661	Sarcophilus harrisii	55.10	0.00e+00	764.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	42.77	5.00e-78	285.00
IUUC-Spo-108300	Schizosaccharomyces pombe	41.35	5.00e-77	282.00
IUUC-Smo-109615	Selaginella moellendorffii	43.17	2.00e-78	286.00
IUUC-Sit-110160	Setaria italica	42.70	2.00e-75	276.00
IUUC-Sly-111164	Solanum lycopersicum	38.48	6.00e-77	281.00
IUUC-Stu-112685	Solanum tuberosum	41.32	1.00e-63	237.00
IUUC-Sar-113692	Sorex araneus	66.89	0.00e+00	772.00
IUUC-Sbi-114301	Sorghum bicolor	41.74	2.00e-74	273.00
IUUC-Sre-115013	Sporisorium reilianum	41.91	6.00e-74	271.00
IUUC-Ssc-115724	Sus scrofa	83.12	0.00e+00	1394.00
IUUC-Tgu-116605	Taeniopygia guttata	46.82	0.00e+00	647.00
IUUC-Tru-117614	Takifugu rubripes	53.77	0.00e+00	815.00
IUUC-Tsy-118807	Tarsius syrichta	77.51	0.00e+00	1035.00
IUUC-Tni-119809	Tetraodon nigroviridis	54.00	0.00e+00	741.00
IUUC-Tca-121312	Theobroma cacao	37.90	5.00e-74	271.00
IUUC-Tre-121930	Trichoderma reesei	38.46	6.00e-69	255.00
IUUC-Tvi-122373	Trichoderma virens	39.95	7.00e-69	255.00
IUUC-Tae-123064	Triticum aestivum	42.39	4.00e-77	281.00
IUUC-Tme-127027	Tuber melanosporum	41.26	2.00e-63	236.00
IUUC-Tbe-127675	Tupaia belangeri	69.03	8.00e-131	461.00
IUUC-Ttr-128411	Tursiops truncatus	75.19	0.00e+00	1730.00
IUUC-Uma-129408	Ustilago maydis	45.78	6.00e-69	255.00
IUUC-Vda-129994	Verticillium dahliae	36.27	3.00e-63	236.00
IUUC-Vpa-130525	Vicugna pacos	82.45	2.00e-65	243.00
IUUC-Vvi-131038	Vitis vinifera	40.00	3.00e-76	279.00
IUUC-Xtr-132618	Xenopus tropicalis	53.76	0.00e+00	891.00
IUUC-Xma-133730	Xiphophorus maculatus	48.35	0.00e+00	658.00
IUUC-Yli-134680	Yarrowia lipolytica	41.49	1.00e-74	274.00
IUUC-Zma-135110	Zea mays	41.74	3.00e-74	272.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence