iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090957

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03075657

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000002261.5	ENSPTRT00000004144.3	ENSPTRP00000003825.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	98.16	0.00e+00	2164.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	29.14	5.00e-42	167.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MSYKVTSGCH WTCQVPESCD NGLHCAGPLG HLHRRCQRTS AHLLVFTEHA EMRRFKRKHL 60
TAIDCQHLAR SHLAVTQPFG QRWTNRDANH GLYPKPRTKR GSRGQGSQRC IPEFFLAGKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTACA AGGTGACTTC AGGCGAGTCC TCTCTGATCC CCAGCTTAAT CATGGCACAA 60
TTGTAGGATT GCTTTGAGGG TCAGACGAGA ATATAGGAAA GAACTGCAAA AGCTGTAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	28.06	2.00e-04	42.00
IUUC-Aml-001396	Ailuropoda melanoleuca	91.39	0.00e+00	1932.00
IUUC-Atr-002826	Amborella trichopoda	41.27	1.00e-03	39.70
IUUC-Apl-003317	Anas platyrhynchos	48.75	0.00e+00	951.00
IUUC-Aca-004498	Anolis carolinensis	54.57	0.00e+00	949.00
IUUC-Ath-007293	Arabidopsis thaliana	35.29	5.00e-03	37.40
IUUC-Ago-007983	Ashbya gossypii	35.71	1.80e+00	28.90
IUUC-Ani-009226	Aspergillus nidulans	32.50	1.00e-06	48.50
IUUC-Ate-010526	Aspergillus terreus	38.24	1.00e-03	39.30
IUUC-Ame-011808	Astyanax mexicanus	59.08	3.00e-133	468.00
IUUC-Bta-013250	Bos taurus	88.99	0.00e+00	1880.00
IUUC-Bol-015348	Brassica oleracea	37.68	4.00e-03	37.70
IUUC-Cja-019638	Callithrix jacchus	97.29	0.00e+00	2100.00
IUUC-Cfa-020195	Canis familiaris	92.92	0.00e+00	1856.00
IUUC-Cpo-022269	Cavia porcellus	86.75	0.00e+00	1805.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	40.28	3.00e-08	54.70
IUUC-Csa-024060	Chlorocebus sabaeus	98.44	0.00e+00	1866.00
IUUC-Cho-025003	Choloepus hoffmanni	89.39	0.00e+00	727.00
IUUC-Cin-025694	Ciona intestinalis	28.57	7.00e-32	131.00
IUUC-Cgl-026626	Colletotrichum gloeosporioides	45.71	1.40e-02	35.40
IUUC-Dre-028083	Danio rerio	44.66	0.00e+00	859.00
IUUC-Dno-029203	Dasypus novemcinctus	87.93	0.00e+00	1779.00
IUUC-Dor-030477	Dipodomys ordii	79.07	0.00e+00	797.00
IUUC-Ete-032861	Echinops telfairi	88.79	0.00e+00	1859.00
IUUC-Eca-033205	Equus caballus	92.27	0.00e+00	1989.00
IUUC-Eeu-034784	Erinaceus europaeus	85.84	0.00e+00	1194.00
IUUC-Fca-035797	Felis catus	90.94	0.00e+00	1948.00
IUUC-Gmo-038855	Gadus morhua	46.27	3.00e-126	446.00
IUUC-Gga-040326	Gallus gallus	50.87	0.00e+00	996.00
IUUC-Gac-042240	Gasterosteus aculeatus	42.57	0.00e+00	749.00
IUUC-Ggo-045050	Gorilla gorilla	95.67	0.00e+00	2064.00
IUUC-Hsa-046650	Homo sapiens	98.25	0.00e+00	2167.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	97.34	0.00e+00	758.00
IUUC-Lch-050231	Latimeria chalumnae	42.91	3.00e-171	595.00
IUUC-Loc-051884	Lepisosteus oculatus	49.76	0.00e+00	982.00
IUUC-Lma-053267	Leptosphaeria maculans	22.53	1.00e-04	42.40
IUUC-Laf-053843	Loxodonta africana	91.21	0.00e+00	1934.00
IUUC-Mcc-055570	Macaca mulatta	96.22	0.00e+00	2123.00
IUUC-Meu-056798	Macropus eugenii	67.68	6.00e-154	538.00
IUUC-Mtr-057915	Medicago truncatula	38.24	3.00e-05	44.70
IUUC-Mla-058841	Melampsora laricipopulina	28.26	1.90e-02	32.00
IUUC-Mga-059648	Meleagris gallopavo	51.71	0.00e+00	956.00
IUUC-Mmr-060757	Microcebus murinus	90.46	0.00e+00	1916.00
IUUC-Mdo-061913	Monodelphis domestica	69.72	0.00e+00	1379.00
IUUC-Mmu-064337	Mus musculus	90.05	0.00e+00	1930.00
IUUC-Mpu-066483	Mustela putorius furo	90.04	0.00e+00	1935.00
IUUC-Mlu-068204	Myotis lucifugus	85.54	0.00e+00	1817.00
IUUC-Ncr-068735	Neurospora crassa	35.94	6.00e-03	37.00
IUUC-Nle-070053	Nomascus leucogenys	97.70	0.00e+00	2115.00
IUUC-Opr-070588	Ochotona princeps	83.80	0.00e+00	1800.00
IUUC-Ont-072655	Oreochromis niloticus	48.00	0.00e+00	758.00
IUUC-Oan-073351	Ornithorhynchus anatinus	63.11	0.00e+00	1326.00
IUUC-Ocu-074465	Oryctolagus cuniculus	90.74	0.00e+00	1851.00
IUUC-Obr-076710	Oryza brachyantha	35.29	4.00e-03	37.70
IUUC-Oin-079176	Oryza indica	23.62	2.00e-05	43.90
IUUC-Opu-083155	Oryza punctata	47.50	3.00e-03	37.40
IUUC-Olu-087831	Ostreococcus lucimarinus	32.14	3.00e-66	248.00
IUUC-Oga-089088	Otolemur garnettii	91.30	0.00e+00	1883.00
IUUC-Oar-089870	Ovis aries	87.83	0.00e+00	1827.00
IUUC-Pan-092632	Papio anubis	98.45	0.00e+00	2019.00
IUUC-Psi-093035	Pelodiscus sinensis	56.11	0.00e+00	1144.00
IUUC-Pno-094870	Phaeosphaeria nodorum	25.27	4.00e-05	43.90
IUUC-Ppa-095660	Physcomitrella patens	38.36	9.00e-04	39.70
IUUC-Pfo-096902	Poecilia formosa	45.63	0.00e+00	687.00
IUUC-Pab-098206	Pongo abelii	98.28	0.00e+00	1925.00
IUUC-Pop-098801	Populus trichocarpa	37.68	8.00e-05	43.10
IUUC-Pca-100238	Procavia capensis	83.64	0.00e+00	1824.00
IUUC-Ppe-101748	Prunus persica	33.82	4.00e-03	37.40
IUUC-Pva-103182	Pteropus vampyrus	86.23	0.00e+00	1849.00
IUUC-Pte-104033	Pyrenophora teres	24.29	2.00e-04	41.60
IUUC-Pyt-104599	Pyrenophora triticirepentis	24.29	1.00e-04	42.00
IUUC-Rno-105141	Rattus norvegicus	89.57	0.00e+00	1922.00
IUUC-Sce-106341	Saccharomyces cerevisiae	25.76	2.00e-03	37.70
IUUC-Sha-106827	Sarcophilus harrisii	67.92	0.00e+00	1441.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	29.14	3.00e-43	170.00
IUUC-Spo-108147	Schizosaccharomyces pombe	29.14	2.00e-42	167.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	24.24	7.00e-04	39.70
IUUC-Sly-111170	Solanum lycopersicum	37.88	5.00e-03	36.20
IUUC-Sre-115025	Sporisorium reilianum	34.39	4.00e-39	156.00
IUUC-Ssc-116188	Sus scrofa	94.30	0.00e+00	1279.00
IUUC-Tgu-116612	Taeniopygia guttata	57.80	5.00e-163	567.00
IUUC-Tsy-119560	Tarsius syrichta	83.47	2.00e-117	417.00
IUUC-Tni-120734	Tetraodon nigroviridis	45.66	0.00e+00	711.00
IUUC-Tca-121338	Theobroma cacao	31.78	2.00e-03	38.10
IUUC-Tre-122089	Trichoderma reesei	40.74	2.00e-04	41.20
IUUC-Tae-125126	Triticum aestivum	36.23	8.00e-04	38.10
IUUC-Tme-127009	Tuber melanosporum	23.10	2.00e-04	41.60
IUUC-Tbe-127431	Tupaia belangeri	88.84	0.00e+00	1703.00
IUUC-Ttr-128744	Tursiops truncatus	85.24	0.00e+00	1828.00
IUUC-Uma-129536	Ustilago maydis	34.78	3.00e-40	160.00
IUUC-Vpa-130123	Vicugna pacos	69.31	3.00e-110	392.00
IUUC-Vvi-131025	Vitis vinifera	36.76	6.00e-04	40.00
IUUC-Xtr-132902	Xenopus tropicalis	58.66	0.00e+00	1012.00
IUUC-Xma-133978	Xiphophorus maculatus	45.94	5.00e-154	538.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence