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Tag Content
iUUCD ID IUUC-Ago-007981
Ensembl Protein ID AAS53381
UniProt Accession Q754R2; DDI1_ASHGO
Genbank Protein ID AAS53381.1
Protein Name DNA damage-inducible protein 1
Genbank Nucleotide ID AE016819
Gene Name DDI1; AFR010C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AGOS_AFR010C AAS53381 AAS53381
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/UBA 2.40e-06 25.5 437 471
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBA
   S: 5    dkleqlveMGFdreealqaLraannnleaAveyLl 39
           + ++ l++ GF+r e+l+aL  + +n+e A+++L+
   Q: 437  EDVRRLMDLGFSRAEVLKALDHSQGNAEYAAAFLF 471
           6799******************************8 PP
   
Organism Ashbya gossypii
Functional Description
(View)

Functional Description


     Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control and may be involved in the regulation of exocytosis (By similarity).
 Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control and may be involved in the regulation of exocytosis (By similarity).
Protein Sequence
(Fasta)
MNVTVSNEVT DELLGPFELS DDITLMDFMA LIDFDENEQA LWHNMRQLKS VDREKTLMQL 60
GIVGESLVVV KAIKKKATEG STTRASKASA KAAKAAAKAA AVARDTPAEQ ATTVSPVAQV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ago-007981|UBD,UBA|Ashbya gossypii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAACGTTA CCGTCAGTAA TGAAGTCACG GACGAGCTCT TAGGTCCATT CGAGTTGAGC 60
GATGATATAA CCTTGATGGA CTTCATGGCA CTTATAGACT TCGATGAGAA TGAACAGGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ago-007981|UBD,UBA|Ashbya gossypii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
Interpro

IPR033322--DDI1
IPR001995--Peptidase_A2_cat
IPR019103--Peptidase_aspartic_DDI1-type
IPR021109--Peptidase_aspartic_dom
IPR015940--UBA
IPR009060--UBA-like
PROSITE

PS50030--UBA
Pfam

PF09668--Asp_protease
PF00627--UBA
SMART

SM00165--UBA
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0009306--P:protein secretion
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0016192--P:vesicle-mediated transport
KEGG ago:AGOS_AFR010C
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000989 Aegilops tauschii 40.74 2.00e-56 211.00
IUUC-Aml-001440 Ailuropoda melanoleuca 57.89 1.00e-50 191.00
IUUC-Atr-002722 Amborella trichopoda 44.66 4.00e-57 213.00
IUUC-Apl-003902 Anas platyrhynchos 59.85 5.00e-43 165.00
IUUC-Aca-004811 Anolis carolinensis 58.48 2.00e-51 193.00
IUUC-Aly-006104 Arabidopsis lyrata 49.35 5.00e-19 85.50
IUUC-Ath-007673 Arabidopsis thaliana 42.27 2.00e-60 223.00
IUUC-Acl-008073 Aspergillus clavatus 38.51 4.00e-49 186.00
IUUC-Afl-008728 Aspergillus flavus 42.96 3.00e-55 206.00
IUUC-Afu-008934 Aspergillus fumigatus 43.54 8.00e-50 188.00
IUUC-Ani-009436 Aspergillus nidulans 44.40 5.00e-52 196.00
IUUC-Ang-009596 Aspergillus niger 46.55 7.00e-48 181.00
IUUC-Aor-009968 Aspergillus oryzae 42.96 3.00e-55 206.00
IUUC-Ate-010376 Aspergillus terreus 46.12 5.00e-49 186.00
IUUC-Ame-011570 Astyanax mexicanus 57.47 3.00e-51 193.00
IUUC-Bgr-012020 Blumeria graminis 48.06 1.00e-62 231.00
IUUC-Bta-012334 Bos taurus 57.89 1.00e-50 191.00
IUUC-Bci-013907 Botrytis cinerea 46.62 1.00e-61 228.00
IUUC-Bdi-014595 Brachypodium distachyon 43.84 2.00e-58 217.00
IUUC-Bol-015258 Brassica oleracea 45.98 9.00e-60 221.00
IUUC-Bra-016740 Brassica rapa 45.98 1.00e-59 221.00
IUUC-Cel-018415 Caenorhabditis elegans 48.68 1.00e-36 145.00
IUUC-Cja-018968 Callithrix jacchus 57.89 1.00e-50 191.00
IUUC-Cfa-020256 Canis familiaris 62.41 5.00e-38 149.00
IUUC-Cpo-022103 Cavia porcellus 60.90 3.00e-43 167.00
IUUC-Cre-022841 Chlamydomonas reinhardtii 46.07 1.00e-45 174.00
IUUC-Csa-023591 Chlorocebus sabaeus 58.48 5.00e-52 197.00
IUUC-Cho-024777 Choloepus hoffmanni 39.02 1.00e-24 105.00
IUUC-Cin-025396 Ciona intestinalis 37.06 6.00e-24 101.00
IUUC-Csv-026270 Ciona savignyi 39.64 3.00e-48 183.00
IUUC-Cgl-026570 Colletotrichum gloeosporioides 58.12 4.00e-51 192.00
IUUC-Cne-026974 Cryptococcus neoformans 35.81 8.00e-57 212.00
IUUC-Cme-027324 Cyanidioschyzon merolae 45.41 1.00e-39 154.00
IUUC-Dre-028030 Danio rerio 59.52 5.00e-52 196.00
IUUC-Dno-029264 Dasypus novemcinctus 57.89 1.00e-50 191.00
IUUC-Dor-030621 Dipodomys ordii 53.97 1.00e-13 68.20
IUUC-Dse-031264 Dothistroma septosporum 58.33 3.00e-07 47.00
IUUC-Dme-032067 Drosophila melanogaster 37.12 2.00e-48 184.00
IUUC-Ete-032664 Echinops telfairi 60.17 1.00e-32 131.00
IUUC-Eca-033648 Equus caballus 57.89 1.00e-50 191.00
IUUC-Eeu-035148 Erinaceus europaeus 57.58 2.00e-36 144.00
IUUC-Fca-035939 Felis catus 61.65 2.00e-37 147.00
IUUC-Fal-037210 Ficedula albicollis 25.00 7.00e-07 45.40
IUUC-Fox-037786 Fusarium oxysporum 57.96 3.00e-50 190.00
IUUC-Fso-038336 Fusarium solani 39.39 3.50e-02 30.80
IUUC-Gmo-039324 Gadus morhua 53.85 1.00e-50 191.00
IUUC-Ggr-039750 Gaeumannomyces graminis 44.78 8.00e-50 188.00
IUUC-Gga-040917 Gallus gallus 58.88 4.00e-31 125.00
IUUC-Gac-041785 Gasterosteus aculeatus 56.00 1.00e-50 191.00
IUUC-Gma-043134 Glycine max 44.83 2.00e-57 213.00
IUUC-Ggo-044472 Gorilla gorilla 61.54 2.00e-36 144.00
IUUC-Hsa-046783 Homo sapiens 58.48 1.00e-51 194.00
IUUC-Hvu-047222 Hordeum vulgare 43.27 4.00e-57 213.00
IUUC-Itr-048836 Ictidomys tridecemlineatus 57.89 1.00e-50 191.00
IUUC-Kpa-049208 Komagataella pastoris 44.65 4.00e-71 259.00
IUUC-Lch-049953 Latimeria chalumnae 58.33 6.00e-52 197.00
IUUC-Lpe-050925 Leersia perrieri 43.13 3.00e-49 186.00
IUUC-Loc-052009 Lepisosteus oculatus 47.43 2.00e-54 204.00
IUUC-Lma-053305 Leptosphaeria maculans 53.89 2.00e-48 184.00
IUUC-Laf-054229 Loxodonta africana 57.89 1.00e-50 191.00
IUUC-Mcc-054796 Macaca mulatta 58.48 4.00e-52 197.00
IUUC-Meu-055944 Macropus eugenii 46.99 7.00e-35 139.00
IUUC-Mpo-057402 Magnaporthe poae 56.29 2.00e-50 190.00
IUUC-Mtr-058061 Medicago truncatula 30.11 5.00e-03 32.30
IUUC-Mla-058983 Melampsora laricipopulina 32.48 9.00e-08 47.80
IUUC-Mga-059910 Meleagris gallopavo 58.43 2.00e-50 190.00
IUUC-Mvi-060225 Microbotryum violaceum 42.02 4.00e-50 189.00
IUUC-Mmr-061679 Microcebus murinus 57.58 2.00e-43 167.00
IUUC-Mdo-062992 Monodelphis domestica 59.04 9.00e-52 195.00
IUUC-Mmu-064298 Mus musculus 60.15 7.00e-43 165.00
IUUC-Mac-064640 Musa acuminata 44.64 2.00e-59 220.00
IUUC-Mpu-066770 Mustela putorius furo 56.90 2.00e-41 160.00
IUUC-Mlu-067804 Myotis lucifugus 58.48 4.00e-51 192.00
IUUC-Nfi-068555 Neosartorya fischeri 43.54 7.00e-50 189.00
IUUC-Ncr-068839 Neurospora crassa 48.02 8.00e-58 215.00
IUUC-Nle-069089 Nomascus leucogenys 58.48 6.00e-52 197.00
IUUC-Opr-070199 Ochotona princeps 61.59 9.00e-47 178.00
IUUC-Ont-072300 Oreochromis niloticus 55.37 6.00e-49 185.00
IUUC-Oan-073421 Ornithorhynchus anatinus 58.48 1.00e-51 194.00
IUUC-Ocu-074510 Oryctolagus cuniculus 60.15 2.00e-43 167.00
IUUC-Oba-075183 Oryza barthii 42.41 4.00e-59 219.00
IUUC-Obr-076044 Oryza brachyantha 46.09 5.00e-59 219.00
IUUC-Ogl-077284 Oryza glaberrima 45.17 3.00e-57 213.00
IUUC-Ogu-078171 Oryza glumaepatula 45.17 3.00e-57 213.00
IUUC-Oin-079871 Oryza indica 45.59 1.00e-58 218.00
IUUC-Olo-080579 Oryza longistaminata 45.59 4.00e-58 216.00
IUUC-Ome-081972 Oryza meridionalis 45.59 1.00e-58 218.00
IUUC-Oni-083027 Oryza nivara 45.17 3.00e-57 213.00
IUUC-Opu-083491 Oryza punctata 45.17 2.00e-57 214.00
IUUC-Oru-084589 Oryza rufipogon 45.17 3.00e-57 213.00
IUUC-Osa-085703 Oryza sativa 45.17 3.00e-57 213.00
IUUC-Ola-086911 Oryzias latipes 50.72 7.00e-15 72.00
IUUC-Olu-087654 Ostreococcus lucimarinus 42.59 1.00e-50 191.00
IUUC-Oga-089146 Otolemur garnettii 58.65 6.00e-35 139.00
IUUC-Oar-089924 Ovis aries 57.89 1.00e-50 191.00
IUUC-Ptr-090938 Pan troglodytes 58.48 1.00e-51 194.00
IUUC-Pan-091767 Papio anubis 58.48 1.00e-51 194.00
IUUC-Psi-093426 Pelodiscus sinensis 58.48 1.00e-51 194.00
IUUC-Pma-094691 Petromyzon marinus 38.46 6.50e-02 29.60
IUUC-Pno-094977 Phaeosphaeria nodorum 39.87 6.00e-50 189.00
IUUC-Ppa-095744 Physcomitrella patens 47.51 4.00e-60 223.00
IUUC-Pfo-097404 Poecilia formosa 53.37 4.00e-50 189.00
IUUC-Pab-098128 Pongo abelii 58.48 1.00e-51 194.00
IUUC-Pop-099053 Populus trichocarpa 46.79 3.00e-61 226.00
IUUC-Pca-100554 Procavia capensis 58.46 1.00e-41 161.00
IUUC-Ppe-101690 Prunus persica 46.36 9.00e-59 218.00
IUUC-Pva-102638 Pteropus vampyrus 42.69 2.00e-28 117.00
IUUC-Pgr-103310 Puccinia graminis 64.44 2.00e-14 69.30
IUUC-Ptt-103798 Puccinia triticina 43.43 1.00e-49 188.00
IUUC-Pte-104408 Pyrenophora teres 53.89 3.00e-48 183.00
IUUC-Pyt-104420 Pyrenophora triticirepentis 53.89 3.00e-48 184.00
IUUC-Rno-105333 Rattus norvegicus 57.89 6.00e-51 194.00
IUUC-Sce-106167 Saccharomyces cerevisiae 51.42 5.00e-94 335.00
IUUC-Sha-107599 Sarcophilus harrisii 59.04 1.00e-51 194.00
IUUC-Sja-107968 Schizosaccharomyces japonicus 57.69 9.00e-49 185.00
IUUC-Spo-108130 Schizosaccharomyces pombe 44.62 2.00e-54 203.00
IUUC-Ssl-108671 Sclerotinia sclerotiorum 46.44 1.00e-60 225.00
IUUC-Sit-109819 Setaria italica 44.63 5.00e-61 226.00
IUUC-Sly-110983 Solanum lycopersicum 45.98 6.00e-61 225.00
IUUC-Stu-112218 Solanum tuberosum 41.18 3.00e-60 223.00
IUUC-Sar-113702 Sorex araneus 26.36 5.00e-07 45.10
IUUC-Sbi-114118 Sorghum bicolor 45.04 2.00e-60 224.00
IUUC-Sre-115084 Sporisorium reilianum 54.93 2.00e-42 164.00
IUUC-Ssc-115545 Sus scrofa 57.89 9.00e-51 191.00
IUUC-Tgu-117353 Taeniopygia guttata 58.43 1.00e-50 191.00
IUUC-Tru-117838 Takifugu rubripes 54.59 1.00e-51 194.00
IUUC-Tsy-118783 Tarsius syrichta 60.38 3.00e-31 127.00
IUUC-Tni-120287 Tetraodon nigroviridis 56.57 4.00e-51 192.00
IUUC-Tca-121513 Theobroma cacao 44.66 2.00e-56 210.00
IUUC-Tae-125471 Triticum aestivum 41.08 1.00e-56 211.00
IUUC-Tur-126159 Triticum urartu 44.49 4.00e-55 206.00
IUUC-Tme-127088 Tuber melanosporum 46.59 9.00e-57 211.00
IUUC-Tbe-127948 Tupaia belangeri 59.40 7.00e-43 165.00
IUUC-Ttr-128560 Tursiops truncatus 57.89 8.00e-51 192.00
IUUC-Uma-129478 Ustilago maydis 50.81 1.00e-43 168.00
IUUC-Vda-129758 Verticillium dahliae 57.06 2.00e-50 190.00
IUUC-Vpa-130132 Vicugna pacos 60.40 1.00e-47 181.00
IUUC-Vvi-131006 Vitis vinifera 45.95 1.00e-52 198.00
IUUC-Xtr-132758 Xenopus tropicalis 57.31 2.00e-50 190.00
IUUC-Xma-133125 Xiphophorus maculatus 53.09 5.00e-49 186.00
IUUC-Yli-134530 Yarrowia lipolytica 35.65 1.00e-51 194.00
IUUC-Zma-135856 Zea mays 45.74 2.00e-59 220.00
Created Date 25-Jun-2017

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