iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mvi-060514

Ensembl Protein ID

MVLG_03979T0

UniProt Accession

U5H9U1; U5H9U1_USTV1

Genbank Protein ID

KDE05607.1

Protein Name

Ubiquitin-conjugating enzyme E2-18 kDa

Genbank Nucleotide ID

AEIJ01000388

Gene Name

MVLG_03979

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MVLG_03979	MVLG_03979T0	MVLG_03979T0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.50e-48	162.0	15	166

Active Site

Position(s)	Description	Evidence
98	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp..egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk........ 87
           Rl+ e+k+l++++   + ++a+p +e+d++ w++li Gp++tp+eggvF++e++fp+dYP++PPk+kf+ ++fhPn+y++G+vC+sil+        
   Q: 15   RLMTEYKQLTASENedSMFTAGPISENDFFIWSALIQGPSETPFEGGVFEAELTFPRDYPLSPPKMKFTPPLFHPNIYASGDVCISILHspgddpna 111
           89*******76555227899********************************************************************889999999 PP
   S: 88   ...eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
              ++e+Wsp++sve++lls++s+laepn+es++n +a++l+++nre+y+ ++r+
   Q: 112  yesSSERWSPVQSVEKILLSVISMLAEPNIESGANIDACKLYRDNREAYDDMIRQ 166
           9999***********************************************9986 PP

Organism

Microbotryum violaceum

Protein Sequence
(Fasta)

MNSNNRSAMN TALKRLMTEY KQLTASENED SMFTAGPISE NDFFIWSALI QGPSETPFEG 60
GVFEAELTFP RDYPLSPPKM KFTPPLFHPN IYASGDVCIS ILHSPGDDPN AYESSSERWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCACTTCGCT CCTCGCCTCT TCATCTCTCC AATCTCCGTG CGATCCTGAC CAGTTCGATC 60
CAGCCCGTCT CCAACTCAAA GTCCTCATCA TGAACTCGAA CAACCGATCA GCGATGAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0000837--C:Doa10p ubiquitin ligase complex
GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006333--P:chromatin assembly or disassembly
GO:0030466--P:chromatin silencing at silent mating-type cassette
GO:0031505--P:fungal-type cell wall organization
GO:0010620--P:negative regulation of transcription by transcription factor catabolism
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002172	Ailuropoda melanoleuca	62.26	8.00e-54	201.00
IUUC-Apl-003761	Anas platyrhynchos	60.98	3.00e-55	205.00
IUUC-Aca-005062	Anolis carolinensis	64.85	4.00e-58	214.00
IUUC-Ago-007853	Ashbya gossypii	61.82	2.00e-61	226.00
IUUC-Acl-008080	Aspergillus clavatus	62.05	4.00e-57	211.00
IUUC-Afl-008478	Aspergillus flavus	61.45	1.00e-56	209.00
IUUC-Afu-009051	Aspergillus fumigatus	62.05	4.00e-57	211.00
IUUC-Ani-009271	Aspergillus nidulans	66.43	1.00e-50	190.00
IUUC-Ang-009748	Aspergillus niger	62.05	4.00e-57	211.00
IUUC-Aor-010228	Aspergillus oryzae	62.05	1.00e-56	210.00
IUUC-Ate-010293	Aspergillus terreus	62.05	2.00e-57	212.00
IUUC-Ame-011698	Astyanax mexicanus	67.27	2.00e-62	229.00
IUUC-Bgr-012226	Blumeria graminis	57.49	5.00e-55	204.00
IUUC-Bta-013277	Bos taurus	69.11	3.00e-47	178.00
IUUC-Bci-013676	Botrytis cinerea	59.28	5.00e-56	208.00
IUUC-Cel-018676	Caenorhabditis elegans	62.58	2.00e-56	209.00
IUUC-Cja-019767	Callithrix jacchus	64.85	4.00e-59	218.00
IUUC-Cfa-020047	Canis familiaris	66.06	5.00e-60	221.00
IUUC-Cpo-021507	Cavia porcellus	65.45	2.00e-59	219.00
IUUC-Csa-023745	Chlorocebus sabaeus	61.21	5.00e-55	204.00
IUUC-Cin-025310	Ciona intestinalis	65.06	2.00e-61	226.00
IUUC-Csv-025961	Ciona savignyi	64.46	5.00e-61	224.00
IUUC-Cgl-026553	Colletotrichum gloeosporioides	62.28	1.00e-58	216.00
IUUC-Cne-026903	Cryptococcus neoformans	61.27	2.00e-56	209.00
IUUC-Dre-027900	Danio rerio	67.27	3.00e-62	228.00
IUUC-Dno-029688	Dasypus novemcinctus	61.21	2.00e-54	202.00
IUUC-Dse-031253	Dothistroma septosporum	60.61	4.00e-58	214.00
IUUC-Dme-031849	Drosophila melanogaster	65.45	4.00e-60	221.00
IUUC-Ete-033010	Echinops telfairi	66.67	3.00e-59	218.00
IUUC-Eca-033294	Equus caballus	62.26	2.00e-54	202.00
IUUC-Eeu-034947	Erinaceus europaeus	56.69	6.00e-33	130.00
IUUC-Fca-036442	Felis catus	67.15	1.00e-51	193.00
IUUC-Fal-037188	Ficedula albicollis	62.58	8.00e-54	201.00
IUUC-Fox-037762	Fusarium oxysporum	61.82	3.00e-58	215.00
IUUC-Fso-038181	Fusarium solani	61.82	7.00e-58	214.00
IUUC-Gmo-038663	Gadus morhua	65.45	5.00e-60	221.00
IUUC-Ggr-039808	Gaeumannomyces graminis	61.08	2.00e-58	216.00
IUUC-Gga-040355	Gallus gallus	65.45	4.00e-60	221.00
IUUC-Gac-041847	Gasterosteus aculeatus	66.67	3.00e-61	225.00
IUUC-Ggo-045202	Gorilla gorilla	66.06	5.00e-60	221.00
IUUC-Hsa-046369	Homo sapiens	66.06	5.00e-60	221.00
IUUC-Itr-048349	Ictidomys tridecemlineatus	66.67	3.00e-60	222.00
IUUC-Kpa-049317	Komagataella pastoris	64.24	3.00e-62	229.00
IUUC-Lch-049596	Latimeria chalumnae	60.49	4.00e-55	204.00
IUUC-Loc-052346	Lepisosteus oculatus	69.11	6.00e-48	180.00
IUUC-Lma-053126	Leptosphaeria maculans	65.15	3.00e-52	194.00
IUUC-Laf-054560	Loxodonta africana	67.38	9.00e-54	200.00
IUUC-Mcc-055172	Macaca mulatta	66.06	5.00e-60	221.00
IUUC-Meu-056891	Macropus eugenii	62.26	5.00e-54	201.00
IUUC-Mor-057260	Magnaporthe oryzae	60.48	9.00e-58	213.00
IUUC-Mpo-057468	Magnaporthe poae	60.48	5.00e-58	214.00
IUUC-Mla-059084	Melampsora laricipopulina	70.06	1.00e-74	270.00
IUUC-Mga-059939	Meleagris gallopavo	60.62	4.00e-54	201.00
IUUC-Mmr-061029	Microcebus murinus	65.45	8.00e-60	220.00
IUUC-Mdo-061820	Monodelphis domestica	66.06	4.00e-60	221.00
IUUC-Mmu-063123	Mus musculus	66.06	5.00e-60	221.00
IUUC-Mpu-065866	Mustela putorius furo	61.08	1.00e-54	203.00
IUUC-Mlu-067220	Myotis lucifugus	62.26	5.00e-54	201.00
IUUC-Nfi-068395	Neosartorya fischeri	62.05	4.00e-57	211.00
IUUC-Ncr-068623	Neurospora crassa	61.08	4.00e-57	211.00
IUUC-Nle-070007	Nomascus leucogenys	66.06	5.00e-60	221.00
IUUC-Ont-071736	Oreochromis niloticus	66.06	2.00e-61	226.00
IUUC-Oan-073475	Ornithorhynchus anatinus	67.38	1.00e-53	200.00
IUUC-Ocu-074820	Oryctolagus cuniculus	58.62	4.00e-55	205.00
IUUC-Ola-087571	Oryzias latipes	66.06	5.00e-61	224.00
IUUC-Oar-089706	Ovis aries	66.06	5.00e-60	221.00
IUUC-Ptr-090798	Pan troglodytes	66.06	5.00e-60	221.00
IUUC-Pan-091967	Papio anubis	66.06	5.00e-60	221.00
IUUC-Psi-093524	Pelodiscus sinensis	65.49	3.00e-53	198.00
IUUC-Pma-094602	Petromyzon marinus	69.06	3.00e-54	201.00
IUUC-Pno-094979	Phaeosphaeria nodorum	63.03	1.00e-61	226.00
IUUC-Pfo-097330	Poecilia formosa	66.06	1.00e-60	223.00
IUUC-Pab-098225	Pongo abelii	65.45	2.00e-59	219.00
IUUC-Pca-101040	Procavia capensis	67.38	1.00e-53	200.00
IUUC-Pva-102507	Pteropus vampyrus	53.46	9.00e-43	164.00
IUUC-Pgr-103674	Puccinia graminis	72.16	3.00e-76	275.00
IUUC-Ptt-103840	Puccinia triticina	71.59	6.00e-76	274.00
IUUC-Pte-104389	Pyrenophora teres	60.61	1.00e-59	220.00
IUUC-Pyt-104703	Pyrenophora triticirepentis	61.21	2.00e-59	219.00
IUUC-Rno-105228	Rattus norvegicus	66.06	5.00e-60	221.00
IUUC-Sce-106233	Saccharomyces cerevisiae	62.58	1.00e-58	216.00
IUUC-Sha-107274	Sarcophilus harrisii	60.37	6.00e-55	204.00
IUUC-Sja-107937	Schizosaccharomyces japonicus	68.10	2.00e-63	232.00
IUUC-Spo-108269	Schizosaccharomyces pombe	66.87	3.00e-62	229.00
IUUC-Ssl-108636	Sclerotinia sclerotiorum	61.08	6.00e-58	214.00
IUUC-Sre-114952	Sporisorium reilianum	66.28	3.00e-67	245.00
IUUC-Ssc-115365	Sus scrofa	67.38	7.00e-54	201.00
IUUC-Tgu-116816	Taeniopygia guttata	65.45	4.00e-60	221.00
IUUC-Tni-120278	Tetraodon nigroviridis	63.64	9.00e-59	217.00
IUUC-Tre-122131	Trichoderma reesei	61.08	8.00e-58	214.00
IUUC-Tvi-122669	Trichoderma virens	61.08	2.00e-58	216.00
IUUC-Tme-127052	Tuber melanosporum	64.63	2.00e-60	223.00
IUUC-Tbe-127792	Tupaia belangeri	66.06	5.00e-60	221.00
IUUC-Uma-129587	Ustilago maydis	67.44	3.00e-68	248.00
IUUC-Vda-129914	Verticillium dahliae	60.48	7.00e-58	214.00
IUUC-Xtr-132450	Xenopus tropicalis	66.67	4.00e-61	224.00
IUUC-Xma-133016	Xiphophorus maculatus	66.06	2.00e-60	222.00
IUUC-Yli-134379	Yarrowia lipolytica	61.82	4.00e-59	218.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence