iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000012314.9	ENSDART00000150159.2	ENSDARP00000123830.1
ENSDARG00000012314.9	ENSDART00000167778.1	ENSDARP00000132741.1
ENSDARG00000012314.9	ENSDART00000115250.3	ENSDARP00000097997.2
ENSDARG00000012314.9	ENSDART00000166108.1	ENSDARP00000138813.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.20e-62	212.1	168	657

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+++l+l+       ++l+++++++++ +++++l++lf+ l+ sk+k+v+p+  +++lk++ ++ s
   Q: 168  VGLKNVGNTCWFSAVIQSLFNLLEFQRLVLHysppARMQDLPRNQKEHRNLPFMQELRHLFSLLVGSKRKYVDPSGAVEILKDAFKS-S 255
           6******************************99998889999999999999*******************************99998.9 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           +++qqD++Ef++ lld le++++                   + +e+++ +k k+++++lF g++    + +  +++ + +e f +++l
   Q: 256  ESQQQDVSEFTHKLLDWLEDAFQ------------------IKAEEDREGEKPKNPMVELFYGRFLAVGVLE--GKKFENTEMFGQYPL 324
           9*********************2..................22345788999**************777664..444556899****** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++ +     ++ +++++++lP+vL+++L+Rf+f+++ +++eki++k+efp +L +++
   Q: 325  QVNGFK-----DLHECLEAAMIEGEIES---LHSAENS--AKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPSMLYMDR 403
           ******.....9**************96...5555544..445899******************************************* PP
   S: 264  fcts..................................................................................... 267
           ++ +                                                                                     
   Q: 404  YMDRnreitrikreeirrlkehltvlqqrlerylsygsgpkrfpladvlqyamefasskpvctspvedidttappggtiaqlpppasag 492
           ****8888888888888888888888888888888888888888888888888888888888888888888888888888888777777 PP
   S: 268  .....................peekqke............................................................. 274
                                +     +                                                             
   Q: 493  eqpdacvsaegsgsglqasqqQ-----Qqrvsihkpftqsrvppdlpmhpaprhiteeelrvlesclhrwrsevendtrdlqasisrih 576
           7777777777777777665440.....14556666666666666666666666666667777777777777777777777778888888 PP
   S: 275  .............kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                        ++ Y+L+av+vH+G+++ GHY+ay+++++++ W++++D  Vt++++ee ++++      ++aY+l+Y 
   Q: 577  rtielmysdksmmQVPYRLHAVLVHEGQANAGHYWAYIYDRHHQrWMKYNDIAVTKSSWEELVRDSFggyrnASAYCLMYI 657
           8888888888888***************************98889***************99997779************6 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MTVEQNVLQQ HSQKHQQTLL NQLREVTGTT DVQLLQQALQ VSNGDLVEAV AFLTEKNAKV 60
PQQDEATYYQ TAQITNDRYI SVGSQADTNV IDLTGDDKDD LQRAIALSLE ESNRAFRETG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTATGACGTA AGGGCGCGCG CACGCGTGTG TGATTCAGAC CCAGCTAATG GATGTCAGAG 60
ATGTCAGATG TGACTGTACT GCTCGTGTTC GTCATGGCGC CGTTGCAGCG CGGATGAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0009953--P:dorsal/ventral pattern formation
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001340	Ailuropoda melanoleuca	73.06	0.00e+00	1654.00
IUUC-Apl-004030	Anas platyrhynchos	74.31	0.00e+00	1718.00
IUUC-Aca-004741	Anolis carolinensis	45.26	0.00e+00	936.00
IUUC-Ame-010624	Astyanax mexicanus	81.01	0.00e+00	1301.00
IUUC-Bgr-011993	Blumeria graminis	36.49	6.00e-11	63.90
IUUC-Bta-013166	Bos taurus	76.11	0.00e+00	1176.00
IUUC-Cel-018346	Caenorhabditis elegans	27.88	3.00e-27	118.00
IUUC-Cja-019150	Callithrix jacchus	75.49	0.00e+00	1728.00
IUUC-Cfa-020649	Canis familiaris	75.49	0.00e+00	1733.00
IUUC-Cpo-021807	Cavia porcellus	72.66	0.00e+00	1694.00
IUUC-Csa-023388	Chlorocebus sabaeus	75.61	0.00e+00	1737.00
IUUC-Cho-024343	Choloepus hoffmanni	80.07	2.00e-121	431.00
IUUC-Cin-025302	Ciona intestinalis	37.12	1.00e-99	357.00
IUUC-Cgl-026575	Colletotrichum gloeosporioides	53.19	8.00e-10	60.10
IUUC-Dno-029495	Dasypus novemcinctus	73.55	0.00e+00	1726.00
IUUC-Dor-030948	Dipodomys ordii	62.07	0.00e+00	1135.00
IUUC-Ete-032323	Echinops telfairi	75.83	6.00e-141	495.00
IUUC-Fca-035876	Felis catus	77.08	0.00e+00	1192.00
IUUC-Fal-036762	Ficedula albicollis	76.76	0.00e+00	1036.00
IUUC-Fox-037752	Fusarium oxysporum	24.94	6.00e-15	77.00
IUUC-Gmo-039490	Gadus morhua	77.39	0.00e+00	1748.00
IUUC-Gga-040817	Gallus gallus	76.74	0.00e+00	1783.00
IUUC-Gac-042473	Gasterosteus aculeatus	78.35	0.00e+00	1768.00
IUUC-Ggo-044939	Gorilla gorilla	71.63	0.00e+00	1610.00
IUUC-Hsa-046204	Homo sapiens	77.01	0.00e+00	1205.00
IUUC-Kpa-049349	Komagataella pastoris	26.70	2.00e-09	58.50
IUUC-Lch-049572	Latimeria chalumnae	74.07	0.00e+00	1707.00
IUUC-Loc-052070	Lepisosteus oculatus	83.87	0.00e+00	1881.00
IUUC-Lma-053078	Leptosphaeria maculans	30.56	2.00e-11	65.10
IUUC-Laf-054426	Loxodonta africana	76.55	0.00e+00	1099.00
IUUC-Mcc-055858	Macaca mulatta	75.75	0.00e+00	1758.00
IUUC-Meu-056719	Macropus eugenii	62.53	2.00e-157	550.00
IUUC-Mga-059808	Meleagris gallopavo	77.64	0.00e+00	1242.00
IUUC-Mmr-060987	Microcebus murinus	75.58	0.00e+00	1723.00
IUUC-Mmu-064245	Mus musculus	75.63	0.00e+00	1207.00
IUUC-Mpu-066304	Mustela putorius furo	75.37	0.00e+00	1715.00
IUUC-Mlu-067139	Myotis lucifugus	77.34	0.00e+00	1229.00
IUUC-Nle-069075	Nomascus leucogenys	77.14	0.00e+00	1206.00
IUUC-Ont-072150	Oreochromis niloticus	82.69	0.00e+00	1897.00
IUUC-Oan-073054	Ornithorhynchus anatinus	69.07	0.00e+00	1535.00
IUUC-Ocu-074102	Oryctolagus cuniculus	73.64	0.00e+00	1721.00
IUUC-Ola-086529	Oryzias latipes	75.19	0.00e+00	1700.00
IUUC-Oga-088939	Otolemur garnettii	76.66	0.00e+00	1186.00
IUUC-Oar-090266	Ovis aries	74.93	0.00e+00	1705.00
IUUC-Ptr-090546	Pan troglodytes	77.14	0.00e+00	1206.00
IUUC-Pan-092311	Papio anubis	75.67	0.00e+00	1758.00
IUUC-Psi-093459	Pelodiscus sinensis	83.89	0.00e+00	1097.00
IUUC-Pfo-096726	Poecilia formosa	81.73	0.00e+00	1873.00
IUUC-Pab-097608	Pongo abelii	72.74	0.00e+00	1630.00
IUUC-Pca-100718	Procavia capensis	63.75	0.00e+00	1144.00
IUUC-Pva-103150	Pteropus vampyrus	73.64	0.00e+00	795.00
IUUC-Pte-104300	Pyrenophora teres	36.14	3.00e-11	65.10
IUUC-Pyt-104434	Pyrenophora triticirepentis	43.08	3.00e-11	64.70
IUUC-Rno-105727	Rattus norvegicus	75.03	0.00e+00	1185.00
IUUC-Sha-107051	Sarcophilus harrisii	77.89	0.00e+00	1216.00
IUUC-Ssl-108532	Sclerotinia sclerotiorum	30.21	7.00e-09	57.00
IUUC-Sar-113097	Sorex araneus	70.80	0.00e+00	1066.00
IUUC-Ssc-115877	Sus scrofa	76.82	0.00e+00	1206.00
IUUC-Tgu-117473	Taeniopygia guttata	68.82	0.00e+00	1564.00
IUUC-Tru-118135	Takifugu rubripes	78.87	0.00e+00	1216.00
IUUC-Tsy-119471	Tarsius syrichta	73.02	0.00e+00	1020.00
IUUC-Tni-120139	Tetraodon nigroviridis	75.16	0.00e+00	1097.00
IUUC-Tbe-127549	Tupaia belangeri	72.18	0.00e+00	1100.00
IUUC-Ttr-128896	Tursiops truncatus	69.22	0.00e+00	1535.00
IUUC-Vda-129742	Verticillium dahliae	24.33	1.00e-10	63.20
IUUC-Vpa-130500	Vicugna pacos	77.52	0.00e+00	1106.00
IUUC-Xtr-132896	Xenopus tropicalis	75.13	0.00e+00	1201.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence