iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Stu-112908

Ensembl Protein ID

PGSC0003DMT400075387

UniProt Accession

M1CV29; M1CV29_SOLTU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PGSC0003DMG400029319	PGSC0003DMT400075387	PGSC0003DMT400075387

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.20e-87	295.7	474	800
ULD/UDP/UBQ/UBQ_Other	3.40e-10	40.9	22	97

Active Site

Position(s)	Description	Evidence
775	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpls 93
           l+  l ++f+ Ee+++  Gv re+++l+++el+np   lf+  +nd++ ++pn++s++ +p hl++F+f Gr++++al+++  + + + 
   Q: 474  LRGDLLMQFKHEEAIGS-GVLREWFFLVCRELFNPHKALFVACPNDRRRFFPNSASKV-DPLHLEYFTFCGRMIALALMHKIQIGVVFD 560
           6677889**********.***************************************9.68**************************** PP
   S: 94   ksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrl 182
           + f+ +l g+++sled+ + dp+ly s k+i+e++   +++  l ltf  + e+lg++++ eL+p+G+++ V+ +N+++Yv+l++++r+
   Q: 561  RLFFLQLAGEDISLEDIRDADPTLYSSCKQILEMDPGTVDQDILSLTFAYDVEELGSRTTIELCPDGKDVVVNSKNRKQYVNLLIQHRF 649
           **********************************999999999********************************************** PP
   S: 183  kegikeqveafreGfnev....iplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLq 266
              i++q+++f++Gf+++    i+ +l++++  e+l+ ++ G+ + i+ved+k++t y+ gy+e++++i wFw+++e++s+e++ka+L 
   Q: 650  VIAIASQIAHFSQGFSDIttssIKTSLFRSLYLEDLDKMLDGSgTAISVEDWKAHTDYN-GYEENDRQISWFWKIVEGMSAEKKKALLF 737
           ******************87777888999999**************************5.5**************************** PP
   S: 267  FvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAiee 329
           F+T+   lPl+Gf+ l  rl + r ++s ++lPss+TCf++L++P Y +   +++++ + ++e
   Q: 738  FWTSIRYLPLEGFRGLDSRLCISRTSESSENLPSSQTCFYLLRIPSYCNSVMMQDRIDIITQE 800
           *****************888888889999**************************99877666 PP

ULD/UDP/UBQ/UBQ_Other

   S: 1    vqvtvksldgs.eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           +q++v+sl  + +l ++  + d+V + K ki++ +gip++ qrLiy G+ L     tL+ y++++++ti+l+ k++
   Q: 22   IQFFVRSLSKTeTLVIRGYSNDSVEVTKNKIRMITGIPEDHQRLIYNGRQLsCKSETLSFYNVQNDTTIYLVGKMP 97
           5788888888888888856677******************************6666****************9986 PP

Organism

Solanum tuberosum

Protein Sequence
(Fasta)

MINSDNNCGI TGKRKRTDQT PIQFFVRSLS KTETLVIRGY SNDSVEVTKN KIRMITGIPE 60
DHQRLIYNGR QLSCKSETLS FYNVQNDTTI YLVGKMPSTY DLQTWKITNE IILKISTIME 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTAACA GTGATAACAA CTGCGGTATC ACTGGAAAAC GAAAGAGAAC TGATCAAACT 60
CCGATTCAGT TCTTCGTTCG TTCTTTATCC AAAACAGAAA CCTTAGTTAT TCGAGGTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50237--HECT
PS50053--UBIQUITIN_2

Pfam

PF00632--HECT
PF00240--ubiquitin

SMART

SM00119--HECTc
SM00213--UBQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bci-013995	Botrytis cinerea	31.66	2.00e-53	205.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	27.32	4.00e-56	214.00
IUUC-Cne-026849	Cryptococcus neoformans	33.43	1.00e-55	210.00
IUUC-Dse-031197	Dothistroma septosporum	34.22	2.00e-55	212.00
IUUC-Mpo-057597	Magnaporthe poae	31.54	4.00e-55	211.00
IUUC-Mla-058888	Melampsora laricipopulina	31.82	1.00e-57	215.00
IUUC-Pgr-103465	Puccinia graminis	31.56	8.00e-56	213.00
IUUC-Ptt-103813	Puccinia triticina	29.52	2.00e-46	182.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence