iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007570

UUCD1 version

UUC-ArT-00852

Ensembl Protein ID

AT5G51270.2

UniProt Accession

Q9LU47; PUB53_ARATH

Genbank Protein ID

BAA97390.1; AED96060.1

Protein Name

Putative U-box domain-containing protein 53; Plant U-box protein 53; E3 ubiquitin ligase; RING-type E3 ubiquitin transferase; Serine/threonine-protein kinase

Genbank Nucleotide ID

AB023044; CP002688

Gene Name

PUB53; At5g51270; MWD22.22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G51270	AT5G51270.2	AT5G51270.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
miRTarBase
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.20e-22	79.3	735	805

Active Site

Position(s)	Description	Evidence
582	Proton acceptor	ECO:0000255\|PROSITE-ProRule:PRU00159, ECO:0000255\|PROSITE-ProRule:PRU10027}

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p++f Cp+ +++M++P+++++G+tydr++Ie+w+++ + t+Pvt++pl++ +l Pn+tl + i +w+++n+
   Q: 735  PPSHFFCPLLKDVMKEPCIAADGYTYDRRAIEEWMENHR-TSPVTNSPLQNVNLLPNHTLYAAIVEWRNRNQ 805
           79********************************76666.5***************************9985 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Functions as an E3 ubiquitin ligase.

Protein Sequence
(Fasta)

MDSFFKNSYL DPKAVRAQLP KRADLAAPSE PMTVALAISG SIKSKNVIKW ALNKFGSDKN 60
VTFKLIHIHP KITTLPTASG NIVSISEELE EVAAAYRQKV MQETKETLLK PFKKMCERKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGACAGATTG CTACTGTCTC ATTTGGTTGG AGGAAAGAAT AGGCGATGAG CAGAACCGTT 60
GCTGACCATC TTGCGTAGAG CTGGCTGTGA CATTGTAGAG GCTCTACAAG CCGGTGCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR014729--Rossmann-like_a/b/a_fold
IPR008271--Ser/Thr_kinase_AS
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS51698--U_BOX

Pfam

PF00069--Pkinase
PF04564--U-box

SMART

SM00220--S_TKc
SM00504--Ubox

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006140	Arabidopsis lyrata	87.85	0.00e+00	1369.00
IUUC-Bol-016531	Brassica oleracea	72.83	0.00e+00	1097.00
IUUC-Bra-016886	Brassica rapa	72.45	0.00e+00	1093.00
IUUC-Cre-022669	Chlamydomonas reinhardtii	43.85	2.00e-86	312.00
IUUC-Hvu-047757	Hordeum vulgare	40.07	2.00e-155	542.00
IUUC-Lpe-050717	Leersia perrieri	43.23	2.00e-175	608.00
IUUC-Mtr-058580	Medicago truncatula	50.19	0.00e+00	684.00
IUUC-Oba-075616	Oryza barthii	42.77	3.00e-172	598.00
IUUC-Obr-076215	Oryza brachyantha	43.80	2.00e-175	608.00
IUUC-Ogl-077159	Oryza glaberrima	42.89	1.00e-172	599.00
IUUC-Ogu-078228	Oryza glumaepatula	43.02	5.00e-173	600.00
IUUC-Oin-079079	Oryza indica	42.77	7.00e-172	597.00
IUUC-Ome-081104	Oryza meridionalis	42.89	2.00e-172	598.00
IUUC-Oni-082428	Oryza nivara	43.02	4.00e-173	601.00
IUUC-Opu-083527	Oryza punctata	43.43	5.00e-173	600.00
IUUC-Oru-084678	Oryza rufipogon	42.77	7.00e-172	597.00
IUUC-Osa-086117	Oryza sativa	42.77	7.00e-172	597.00
IUUC-Pca-100370	Procavia capensis	33.53	3.00e-16	80.90
IUUC-Pva-103086	Pteropus vampyrus	33.63	1.00e-25	111.00
IUUC-Tae-125570	Triticum aestivum	39.56	1.00e-138	486.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence