iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033600

UUCD1 version

UUC-EqC-01057

Ensembl Protein ID

ENSECAP00000013938.1

UniProt Accession

F6W2H6; F6W2H6_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000016116.1	ENSECAT00000017188.1	ENSECAP00000013938.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.20e-80	268.5	123	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC++NS++QcL+ +p+l+++ll+ ++ ++++     +   ++l+ +q+ + +   ++ +a++p ++++ lkk+a++f+  +q
   Q: 123  GLHNLGNTCFLNSTVQCLTYTPPLANYLLSrEHARSCH-----QGGFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQ 206
           9*****************************44444444.....346799999999999999**************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++ +d++++++                  ls  a+ + +++ ++l++++F+g l+s++kc  c++vs +++p ld+ l++++
   Q: 207  EDAHEFLRYTIDAMQKAC------------------LSGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQ 277
           ******************..................55566778999****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
                  ++  +Le f+k++ l gen+y c kckkk+ a+k++++++ + vL+l LkRf    ++ s  ki+k v +p+ L+++p++++
   Q: 278  AA-----NIVRALELFVKPDVLSGENAYMCAKCKKKVPASKRFTIHRTSSVLTLSLKRF----ANFSGGKITKDVGYPEFLNIRPYMSQ 357
           **.....9***************************************************....668899******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           ++ +   ++ Y L+av+vHsG s++ GHY++yvk ++g+W++++Ds V++++ + vl+   ++aYvlfY 
   Q: 358  SSGE---PVVYGLYAVLVHSGySCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKVVLN---QQAYVLFYL 421
           5544...9**************************************************...********6 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MPIVDKLKEA LKPGRKDSAD DGELGKLLAS SAKKVLLQKI EFEPASKSFS YQLESLKSKY 60
VLLNPKTEGA SRHRSGDEPQ ARRQGGEHGS EGCGDGVPAP QKVLFPMERL SLKWERVYRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTGTCCCC ACAGTGATGC ACCATGCCAA TAGTTGATAA GTTGAAGGAA GCCCTGAAAC 60
CTGGCCGCAA GGACTCGGCT GACGATGGAG AGCTGGGGAA GCTTCTGGCT TCTTCTGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0016579--P:protein deubiquitination
GO:1903146--P:regulation of mitophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002092	Ailuropoda melanoleuca	79.27	0.00e+00	1450.00
IUUC-Atr-003102	Amborella trichopoda	47.08	7.00e-86	312.00
IUUC-Aca-005360	Anolis carolinensis	63.15	0.00e+00	889.00
IUUC-Aly-006389	Arabidopsis lyrata	32.97	1.00e-77	284.00
IUUC-Ath-006710	Arabidopsis thaliana	38.75	1.00e-77	284.00
IUUC-Bta-013047	Bos taurus	76.33	0.00e+00	1402.00
IUUC-Bdi-014036	Brachypodium distachyon	41.58	2.00e-85	310.00
IUUC-Bol-015086	Brassica oleracea	44.48	1.00e-82	301.00
IUUC-Bra-018046	Brassica rapa	44.48	6.00e-83	302.00
IUUC-Cja-019203	Callithrix jacchus	74.27	0.00e+00	1340.00
IUUC-Cfa-020586	Canis familiaris	80.34	0.00e+00	1537.00
IUUC-Cpo-021804	Cavia porcellus	67.99	0.00e+00	1254.00
IUUC-Cre-022988	Chlamydomonas reinhardtii	46.64	9.00e-52	196.00
IUUC-Csa-023137	Chlorocebus sabaeus	76.19	0.00e+00	1437.00
IUUC-Cin-025230	Ciona intestinalis	52.87	1.00e-97	349.00
IUUC-Cne-027049	Cryptococcus neoformans	33.33	6.00e-39	155.00
IUUC-Cme-027339	Cyanidioschyzon merolae	35.48	2.00e-60	226.00
IUUC-Dre-028587	Danio rerio	74.33	0.00e+00	825.00
IUUC-Dno-029149	Dasypus novemcinctus	70.26	0.00e+00	1298.00
IUUC-Dor-030836	Dipodomys ordii	68.24	0.00e+00	972.00
IUUC-Dme-032119	Drosophila melanogaster	33.19	1.00e-71	264.00
IUUC-Ete-032567	Echinops telfairi	70.50	0.00e+00	860.00
IUUC-Eeu-035206	Erinaceus europaeus	62.65	2.00e-157	550.00
IUUC-Fca-036392	Felis catus	67.53	0.00e+00	746.00
IUUC-Fal-036852	Ficedula albicollis	55.57	4.00e-158	552.00
IUUC-Gmo-039033	Gadus morhua	74.26	0.00e+00	805.00
IUUC-Gga-040664	Gallus gallus	77.29	0.00e+00	760.00
IUUC-Gac-042176	Gasterosteus aculeatus	62.36	0.00e+00	804.00
IUUC-Gma-044075	Glycine max	45.35	2.00e-85	310.00
IUUC-Ggo-045437	Gorilla gorilla	76.92	0.00e+00	1423.00
IUUC-Hsa-046863	Homo sapiens	76.66	0.00e+00	1412.00
IUUC-Hvu-047714	Hordeum vulgare	37.30	8.00e-67	248.00
IUUC-Itr-048655	Ictidomys tridecemlineatus	70.47	0.00e+00	1244.00
IUUC-Lch-050120	Latimeria chalumnae	60.55	0.00e+00	746.00
IUUC-Lpe-051574	Leersia perrieri	41.16	3.00e-80	293.00
IUUC-Loc-052796	Lepisosteus oculatus	74.91	0.00e+00	776.00
IUUC-Laf-054243	Loxodonta africana	71.16	0.00e+00	1325.00
IUUC-Mcc-055762	Macaca mulatta	76.25	0.00e+00	1412.00
IUUC-Meu-056697	Macropus eugenii	67.84	0.00e+00	1291.00
IUUC-Mtr-058537	Medicago truncatula	40.73	2.00e-86	314.00
IUUC-Mla-059049	Melampsora laricipopulina	42.81	2.00e-59	224.00
IUUC-Mga-059359	Meleagris gallopavo	74.94	2.00e-158	553.00
IUUC-Mmr-060966	Microcebus murinus	73.81	0.00e+00	1349.00
IUUC-Mdo-062733	Monodelphis domestica	73.44	0.00e+00	1106.00
IUUC-Mmu-064331	Mus musculus	69.73	0.00e+00	1282.00
IUUC-Mac-064815	Musa acuminata	46.88	3.00e-86	312.00
IUUC-Mpu-065759	Mustela putorius furo	76.96	0.00e+00	1384.00
IUUC-Mlu-067371	Myotis lucifugus	72.31	0.00e+00	1287.00
IUUC-Nle-070087	Nomascus leucogenys	76.22	0.00e+00	1403.00
IUUC-Opr-070729	Ochotona princeps	67.03	0.00e+00	993.00
IUUC-Ont-071346	Oreochromis niloticus	78.16	0.00e+00	811.00
IUUC-Oan-072931	Ornithorhynchus anatinus	75.87	0.00e+00	859.00
IUUC-Ocu-074823	Oryctolagus cuniculus	64.29	0.00e+00	1086.00
IUUC-Oba-075866	Oryza barthii	45.71	1.00e-84	308.00
IUUC-Obr-076408	Oryza brachyantha	45.25	7.00e-85	308.00
IUUC-Ogl-077239	Oryza glaberrima	45.89	2.00e-85	310.00
IUUC-Ogu-078064	Oryza glumaepatula	45.89	2.00e-85	310.00
IUUC-Oin-079157	Oryza indica	42.05	2.00e-85	310.00
IUUC-Olo-080231	Oryza longistaminata	44.30	2.00e-77	284.00
IUUC-Ome-081746	Oryza meridionalis	46.41	3.00e-84	306.00
IUUC-Oni-082339	Oryza nivara	42.05	2.00e-85	310.00
IUUC-Opu-083194	Oryza punctata	41.53	4.00e-85	310.00
IUUC-Oru-085083	Oryza rufipogon	42.05	2.00e-85	310.00
IUUC-Osa-086180	Oryza sativa	42.05	2.00e-85	310.00
IUUC-Ola-087255	Oryzias latipes	73.26	0.00e+00	808.00
IUUC-Olu-087773	Ostreococcus lucimarinus	44.76	6.00e-71	260.00
IUUC-Oga-088818	Otolemur garnettii	73.86	0.00e+00	1162.00
IUUC-Oar-089410	Ovis aries	74.11	0.00e+00	1374.00
IUUC-Ptr-090680	Pan troglodytes	76.23	0.00e+00	1228.00
IUUC-Pan-092482	Papio anubis	76.01	0.00e+00	1428.00
IUUC-Ppa-095853	Physcomitrella patens	47.77	2.00e-92	333.00
IUUC-Pfo-096807	Poecilia formosa	75.23	0.00e+00	825.00
IUUC-Pab-098724	Pongo abelii	76.59	0.00e+00	1445.00
IUUC-Pop-099693	Populus trichocarpa	47.23	1.00e-83	304.00
IUUC-Pca-100117	Procavia capensis	78.89	3.00e-157	549.00
IUUC-Pva-102883	Pteropus vampyrus	68.55	0.00e+00	1127.00
IUUC-Pgr-103270	Puccinia graminis	45.94	9.00e-69	254.00
IUUC-Ptt-103887	Puccinia triticina	44.62	2.00e-68	253.00
IUUC-Rno-105340	Rattus norvegicus	70.32	0.00e+00	1100.00
IUUC-Sha-107019	Sarcophilus harrisii	66.29	0.00e+00	1269.00
IUUC-Sja-107805	Schizosaccharomyces japonicus	42.08	1.00e-75	276.00
IUUC-Spo-108119	Schizosaccharomyces pombe	44.90	7.00e-83	300.00
IUUC-Sit-110536	Setaria italica	46.52	1.00e-80	295.00
IUUC-Sly-111722	Solanum lycopersicum	39.95	2.00e-80	293.00
IUUC-Stu-112912	Solanum tuberosum	40.39	2.00e-81	297.00
IUUC-Sbi-114477	Sorghum bicolor	45.89	2.00e-86	313.00
IUUC-Sre-114924	Sporisorium reilianum	41.07	5.00e-66	245.00
IUUC-Ssc-116022	Sus scrofa	74.29	0.00e+00	1224.00
IUUC-Tgu-116976	Taeniopygia guttata	71.36	1.00e-159	556.00
IUUC-Tru-118391	Takifugu rubripes	64.04	0.00e+00	833.00
IUUC-Tsy-119253	Tarsius syrichta	60.37	0.00e+00	824.00
IUUC-Tni-120064	Tetraodon nigroviridis	79.32	0.00e+00	815.00
IUUC-Tae-125259	Triticum aestivum	48.58	1.00e-88	321.00
IUUC-Tur-126014	Triticum urartu	47.71	2.00e-84	307.00
IUUC-Tbe-127377	Tupaia belangeri	63.41	0.00e+00	819.00
IUUC-Ttr-129259	Tursiops truncatus	70.13	0.00e+00	1186.00
IUUC-Uma-129416	Ustilago maydis	43.50	6.00e-68	252.00
IUUC-Vpa-130568	Vicugna pacos	65.81	9.00e-44	172.00
IUUC-Xtr-132944	Xenopus tropicalis	77.01	0.00e+00	671.00
IUUC-Xma-133735	Xiphophorus maculatus	62.29	0.00e+00	827.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence