iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090144

Ensembl Protein ID

ENSOARP00000019645.1

UniProt Accession

W5QAA2; W5QAA2_SHEEP

Genbank Protein ID

ENSOARP00000019645

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01023134

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000018301.1	ENSOART00000019918.1	ENSOARP00000019645.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.60e-19	69.5	114	177
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.20e-14	50.3	213	244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l v+++ f+ah+ivLaa+S++F a+f++el+e+  k+ v+i+++ ++ ++ ll+F+Yt ++
   Q: 114  CDVTLRVEQQDFPAHRIVLAACSDYFCAMFTSELSEKG-KPYVDIQGLTASTMEILLDFVYTETV 177
           9***********************************98.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fA++++c dL++aa+ f +khF+
   Q: 213  PSNCLGIRDFAETHNCVDLMQAAEVFSQKHFP 244
           89*****************************6 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MARGVQREEG SDLLRGISGW VVLVMPGRGV CSTCGCLSLM APPLFVKLTE YMQCPQAFTR 60
APWLCFLENS RTPFTRSPRC LMRGIMAPKD MMTNTHAKSI LNSMNSLRKS NTLCDVTLRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAAGGG GAGTTCAGAG GGAGGAGGGA TCCGATTTAC TCAGGGGAAT TAGTGGCTGG 60
GTTGTGTTGG TAATGCCAGG AAGAGGCGTG TGCTCTACCT GTGGATGTTT GAGTCTGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0030134--C:ER to Golgi transport vesicle
GO:0000139--C:Golgi membrane
GO:0005815--C:microtubule organizing center
GO:0048208--P:COPII vesicle coating
GO:0006513--P:protein monoubiquitination
GO:0016055--P:Wnt signaling pathway

KEGG

oas:101104167

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002301	Ailuropoda melanoleuca	98.39	0.00e+00	1114.00
IUUC-Apl-003339	Anas platyrhynchos	96.53	0.00e+00	1024.00
IUUC-Aca-004418	Anolis carolinensis	95.57	0.00e+00	1107.00
IUUC-Ath-007066	Arabidopsis thaliana	32.63	2.00e-39	157.00
IUUC-Ame-011906	Astyanax mexicanus	75.18	0.00e+00	872.00
IUUC-Bta-012979	Bos taurus	97.54	0.00e+00	1127.00
IUUC-Cja-019582	Callithrix jacchus	96.23	0.00e+00	1135.00
IUUC-Cfa-020716	Canis familiaris	97.77	0.00e+00	1159.00
IUUC-Cpo-022013	Cavia porcellus	98.77	0.00e+00	1141.00
IUUC-Cre-022752	Chlamydomonas reinhardtii	29.28	1.00e-15	80.10
IUUC-Csa-023424	Chlorocebus sabaeus	98.29	0.00e+00	1053.00
IUUC-Cho-024586	Choloepus hoffmanni	80.46	0.00e+00	887.00
IUUC-Dre-028344	Danio rerio	87.70	3.00e-165	573.00
IUUC-Dno-028854	Dasypus novemcinctus	98.59	0.00e+00	1139.00
IUUC-Dor-030403	Dipodomys ordii	98.42	0.00e+00	1134.00
IUUC-Ete-032963	Echinops telfairi	97.02	0.00e+00	982.00
IUUC-Eca-033282	Equus caballus	98.42	0.00e+00	1138.00
IUUC-Eeu-034933	Erinaceus europaeus	98.82	3.00e-142	498.00
IUUC-Fca-035487	Felis catus	98.59	0.00e+00	1139.00
IUUC-Fal-037059	Ficedula albicollis	95.06	0.00e+00	1103.00
IUUC-Gmo-039564	Gadus morhua	89.38	0.00e+00	1079.00
IUUC-Gga-040629	Gallus gallus	95.73	0.00e+00	1107.00
IUUC-Gac-042526	Gasterosteus aculeatus	89.75	0.00e+00	1078.00
IUUC-Ggo-044839	Gorilla gorilla	98.42	0.00e+00	1138.00
IUUC-Hsa-046742	Homo sapiens	98.42	0.00e+00	1138.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	98.42	0.00e+00	1135.00
IUUC-Lch-049540	Latimeria chalumnae	92.38	0.00e+00	1105.00
IUUC-Loc-051923	Lepisosteus oculatus	92.73	0.00e+00	1080.00
IUUC-Laf-054370	Loxodonta africana	98.06	0.00e+00	1136.00
IUUC-Mcc-054852	Macaca mulatta	98.42	0.00e+00	1138.00
IUUC-Mor-057181	Magnaporthe oryzae	25.75	7.00e-10	58.20
IUUC-Mga-059486	Meleagris gallopavo	94.91	0.00e+00	1013.00
IUUC-Mmr-061777	Microcebus murinus	95.80	0.00e+00	1155.00
IUUC-Mdo-061990	Monodelphis domestica	96.82	0.00e+00	1121.00
IUUC-Mmu-064053	Mus musculus	98.06	0.00e+00	1136.00
IUUC-Mac-064654	Musa acuminata	34.02	4.00e-41	162.00
IUUC-Mpu-066623	Mustela putorius furo	80.42	0.00e+00	825.00
IUUC-Mlu-067648	Myotis lucifugus	96.91	0.00e+00	1176.00
IUUC-Nle-069714	Nomascus leucogenys	98.24	0.00e+00	1137.00
IUUC-Opr-071143	Ochotona princeps	91.73	0.00e+00	1039.00
IUUC-Ont-071848	Oreochromis niloticus	90.78	0.00e+00	1087.00
IUUC-Oan-073041	Ornithorhynchus anatinus	95.36	7.00e-161	559.00
IUUC-Ocu-074379	Oryctolagus cuniculus	97.06	0.00e+00	1143.00
IUUC-Ola-087469	Oryzias latipes	90.43	0.00e+00	1085.00
IUUC-Oga-088004	Otolemur garnettii	97.49	6.00e-139	486.00
IUUC-Ptr-091406	Pan troglodytes	98.42	0.00e+00	1138.00
IUUC-Pan-092762	Papio anubis	97.36	0.00e+00	1118.00
IUUC-Psi-093391	Pelodiscus sinensis	95.21	0.00e+00	1107.00
IUUC-Pma-094134	Petromyzon marinus	73.87	0.00e+00	826.00
IUUC-Pfo-096404	Poecilia formosa	90.28	0.00e+00	1084.00
IUUC-Pab-098425	Pongo abelii	97.70	0.00e+00	1123.00
IUUC-Pop-099216	Populus trichocarpa	33.33	5.00e-31	129.00
IUUC-Pca-101093	Procavia capensis	97.93	2.00e-170	592.00
IUUC-Pva-102239	Pteropus vampyrus	88.03	0.00e+00	1019.00
IUUC-Rno-104921	Rattus norvegicus	98.24	0.00e+00	1140.00
IUUC-Sha-106625	Sarcophilus harrisii	96.57	0.00e+00	1149.00
IUUC-Sly-111482	Solanum lycopersicum	34.58	9.00e-40	158.00
IUUC-Sar-113468	Sorex araneus	86.07	0.00e+00	704.00
IUUC-Ssc-116106	Sus scrofa	97.09	0.00e+00	1155.00
IUUC-Tgu-117402	Taeniopygia guttata	74.20	0.00e+00	748.00
IUUC-Tru-117546	Takifugu rubripes	89.72	0.00e+00	1080.00
IUUC-Tsy-118802	Tarsius syrichta	88.87	0.00e+00	990.00
IUUC-Tni-119999	Tetraodon nigroviridis	89.38	0.00e+00	1072.00
IUUC-Tca-121074	Theobroma cacao	30.96	3.00e-37	150.00
IUUC-Tbe-127987	Tupaia belangeri	98.06	0.00e+00	951.00
IUUC-Ttr-128613	Tursiops truncatus	91.36	0.00e+00	1033.00
IUUC-Xtr-132401	Xenopus tropicalis	90.61	2.00e-171	594.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence