iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020162

Ensembl Protein ID

ENSCAFP00000038502.1

UniProt Accession

J9NYY2; J9NYY2_CANLF

Genbank Protein ID

ENSCAFP00000038502

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03014032

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000029331.1	ENSCAFT00000043303.1	ENSCAFP00000038502.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	90.44	0.00e+00	727.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

SGIMDKSKEN CIAGPVKTAI ALGDGPKRVL VTQQVPSQNP LSANSGQAQR VLCPSNSSQR 60
VPPQTQKLVS SHKPAQNLKQ KQLQATGVPR PASRSLNNTQ KSEQPSSSAP GNNSEKELAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGGCATTA TGGACAAATC TAAAGAAAAC TGCATTGCAG GGCCTGTTAA GGTAAGTTGA 60
ATAATCTTAA ATTTTTTTTT TTTTTTTTTT AAGATTTTAT TCATGAGAAA CACAGGCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0032133--C:chromosome passenger complex
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0051233--C:spindle midzone
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0032465--P:regulation of cytokinesis
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	62.46	2.00e-103	368.00
IUUC-Aml-001426	Ailuropoda melanoleuca	95.90	0.00e+00	785.00
IUUC-Atr-002453	Amborella trichopoda	66.92	1.00e-106	379.00
IUUC-Apl-003626	Anas platyrhynchos	71.83	4.00e-156	544.00
IUUC-Aca-004602	Anolis carolinensis	67.32	2.00e-149	522.00
IUUC-Aly-005878	Arabidopsis lyrata	64.55	1.00e-104	372.00
IUUC-Ath-007117	Arabidopsis thaliana	65.30	4.00e-105	374.00
IUUC-Acl-008199	Aspergillus clavatus	54.36	1.00e-88	320.00
IUUC-Afl-008419	Aspergillus flavus	49.24	2.00e-87	315.00
IUUC-Afu-008751	Aspergillus fumigatus	48.80	4.00e-88	318.00
IUUC-Ani-009181	Aspergillus nidulans	51.12	5.00e-92	331.00
IUUC-Ang-009787	Aspergillus niger	48.18	1.00e-87	316.00
IUUC-Aor-009980	Aspergillus oryzae	49.24	2.00e-87	315.00
IUUC-Ate-010286	Aspergillus terreus	53.12	1.00e-87	316.00
IUUC-Ame-010849	Astyanax mexicanus	59.45	5.00e-129	454.00
IUUC-Bgr-012110	Blumeria graminis	57.19	5.00e-88	317.00
IUUC-Bta-013474	Bos taurus	88.40	0.00e+00	733.00
IUUC-Bci-013756	Botrytis cinerea	57.80	2.00e-94	339.00
IUUC-Bdi-014257	Brachypodium distachyon	63.16	7.00e-105	373.00
IUUC-Bol-016310	Brassica oleracea	61.62	1.00e-102	365.00
IUUC-Bra-017438	Brassica rapa	63.00	2.00e-103	369.00
IUUC-Cel-018157	Caenorhabditis elegans	63.64	4.00e-102	364.00
IUUC-Cja-019282	Callithrix jacchus	88.89	0.00e+00	721.00
IUUC-Cpo-021764	Cavia porcellus	82.06	0.00e+00	661.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	64.60	1.00e-106	379.00
IUUC-Csa-023694	Chlorocebus sabaeus	88.89	0.00e+00	679.00
IUUC-Cho-024350	Choloepus hoffmanni	94.88	1.00e-113	401.00
IUUC-Cin-025542	Ciona intestinalis	71.69	9.00e-118	416.00
IUUC-Csv-025873	Ciona savignyi	67.94	1.00e-118	419.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	50.00	1.00e-80	293.00
IUUC-Cne-026928	Cryptococcus neoformans	60.07	1.00e-95	343.00
IUUC-Cme-027336	Cyanidioschyzon merolae	72.35	4.00e-119	421.00
IUUC-Dre-028198	Danio rerio	61.82	3.00e-132	464.00
IUUC-Dno-029928	Dasypus novemcinctus	86.67	0.00e+00	663.00
IUUC-Dor-030238	Dipodomys ordii	77.53	0.00e+00	635.00
IUUC-Dse-031266	Dothistroma septosporum	54.36	1.00e-92	333.00
IUUC-Dme-032007	Drosophila melanogaster	61.07	3.00e-100	358.00
IUUC-Ete-032911	Echinops telfairi	67.45	2.00e-136	478.00
IUUC-Eca-033749	Equus caballus	91.83	0.00e+00	744.00
IUUC-Eeu-035170	Erinaceus europaeus	87.68	0.00e+00	724.00
IUUC-Fca-035498	Felis catus	93.86	0.00e+00	758.00
IUUC-Fal-037397	Ficedula albicollis	67.87	1.00e-151	529.00
IUUC-Fox-037747	Fusarium oxysporum	53.38	3.00e-91	328.00
IUUC-Fso-038429	Fusarium solani	53.05	3.00e-90	325.00
IUUC-Gmo-039378	Gadus morhua	59.69	5.00e-127	447.00
IUUC-Ggr-039939	Gaeumannomyces graminis	56.90	4.00e-95	341.00
IUUC-Gga-040187	Gallus gallus	71.05	1.00e-154	539.00
IUUC-Gac-042223	Gasterosteus aculeatus	60.15	4.00e-132	464.00
IUUC-Gma-042870	Glycine max	65.54	2.00e-98	351.00
IUUC-Ggo-045617	Gorilla gorilla	89.88	0.00e+00	748.00
IUUC-Hsa-046968	Homo sapiens	89.63	0.00e+00	747.00
IUUC-Hvu-047072	Hordeum vulgare	54.85	4.00e-81	294.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	75.43	2.00e-177	614.00
IUUC-Kpa-049093	Komagataella pastoris	55.72	4.00e-78	285.00
IUUC-Lch-050346	Latimeria chalumnae	66.18	2.00e-149	521.00
IUUC-Lpe-051466	Leersia perrieri	66.67	3.00e-105	374.00
IUUC-Lma-053006	Leptosphaeria maculans	58.94	7.00e-90	323.00
IUUC-Laf-053422	Loxodonta africana	86.42	0.00e+00	713.00
IUUC-Mcc-055245	Macaca mulatta	89.11	0.00e+00	668.00
IUUC-Mor-056952	Magnaporthe oryzae	57.46	5.00e-91	327.00
IUUC-Mpo-057605	Magnaporthe poae	55.97	5.00e-96	344.00
IUUC-Mtr-057726	Medicago truncatula	65.66	1.00e-104	372.00
IUUC-Mla-059174	Melampsora laricipopulina	63.08	2.00e-99	355.00
IUUC-Mga-059562	Meleagris gallopavo	59.95	9.00e-121	426.00
IUUC-Mvi-060305	Microbotryum violaceum	60.58	4.00e-95	341.00
IUUC-Mmr-061588	Microcebus murinus	86.35	0.00e+00	730.00
IUUC-Mdo-061914	Monodelphis domestica	78.57	1.00e-178	619.00
IUUC-Mmu-063288	Mus musculus	81.57	0.00e+00	669.00
IUUC-Mac-064969	Musa acuminata	63.86	3.00e-105	374.00
IUUC-Mpu-066855	Mustela putorius furo	94.32	0.00e+00	765.00
IUUC-Mlu-068046	Myotis lucifugus	89.74	0.00e+00	724.00
IUUC-Nfi-068527	Neosartorya fischeri	56.00	1.00e-87	316.00
IUUC-Ncr-068678	Neurospora crassa	57.09	5.00e-93	334.00
IUUC-Nle-069848	Nomascus leucogenys	89.63	0.00e+00	745.00
IUUC-Opr-070589	Ochotona princeps	79.51	0.00e+00	636.00
IUUC-Ont-071733	Oreochromis niloticus	61.10	2.00e-126	445.00
IUUC-Oan-073399	Ornithorhynchus anatinus	80.91	5.00e-155	540.00
IUUC-Ocu-074063	Oryctolagus cuniculus	84.94	0.00e+00	710.00
IUUC-Oba-075264	Oryza barthii	63.60	9.00e-105	372.00
IUUC-Obr-076048	Oryza brachyantha	65.41	7.00e-104	370.00
IUUC-Ogl-077637	Oryza glaberrima	66.29	7.00e-104	370.00
IUUC-Ogu-078830	Oryza glumaepatula	63.60	6.00e-105	373.00
IUUC-Oin-079150	Oryza indica	63.60	4.00e-105	374.00
IUUC-Olo-080398	Oryza longistaminata	57.26	3.00e-82	298.00
IUUC-Ome-081544	Oryza meridionalis	55.15	1.00e-90	326.00
IUUC-Oni-082250	Oryza nivara	63.60	4.00e-105	374.00
IUUC-Opu-083638	Oryza punctata	63.60	7.00e-105	373.00
IUUC-Oru-084981	Oryza rufipogon	63.60	3.00e-105	374.00
IUUC-Osa-085961	Oryza sativa	63.60	3.00e-105	374.00
IUUC-Olu-087880	Ostreococcus lucimarinus	69.58	1.00e-111	395.00
IUUC-Oga-088891	Otolemur garnettii	86.12	0.00e+00	701.00
IUUC-Oar-090021	Ovis aries	88.21	0.00e+00	718.00
IUUC-Ptr-091458	Pan troglodytes	89.88	0.00e+00	748.00
IUUC-Pan-092546	Papio anubis	88.40	0.00e+00	676.00
IUUC-Psi-093280	Pelodiscus sinensis	73.97	6.00e-164	570.00
IUUC-Pma-094298	Petromyzon marinus	76.60	3.00e-121	427.00
IUUC-Pno-094847	Phaeosphaeria nodorum	57.24	4.00e-89	321.00
IUUC-Ppa-095855	Physcomitrella patens	62.15	1.00e-107	382.00
IUUC-Pfo-096428	Poecilia formosa	59.80	3.00e-131	461.00
IUUC-Pab-098696	Pongo abelii	88.92	0.00e+00	726.00
IUUC-Pop-099405	Populus trichocarpa	63.67	1.00e-104	372.00
IUUC-Pca-100740	Procavia capensis	80.00	0.00e+00	663.00
IUUC-Ppe-101854	Prunus persica	65.54	3.00e-105	374.00
IUUC-Pva-103212	Pteropus vampyrus	90.44	0.00e+00	726.00
IUUC-Pgr-103474	Puccinia graminis	63.26	3.00e-99	355.00
IUUC-Ptt-103933	Puccinia triticina	49.05	8.00e-63	233.00
IUUC-Pte-104089	Pyrenophora teres	49.00	9.00e-90	323.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	49.00	8.00e-90	323.00
IUUC-Rno-105057	Rattus norvegicus	82.47	0.00e+00	676.00
IUUC-Sha-107137	Sarcophilus harrisii	80.71	0.00e+00	637.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	54.87	6.00e-100	357.00
IUUC-Spo-108078	Schizosaccharomyces pombe	60.71	8.00e-103	366.00
IUUC-Smo-109288	Selaginella moellendorffii	65.92	1.00e-106	379.00
IUUC-Sit-110246	Setaria italica	64.73	2.00e-104	372.00
IUUC-Sly-111379	Solanum lycopersicum	63.60	1.00e-105	375.00
IUUC-Stu-112777	Solanum tuberosum	61.49	4.00e-105	374.00
IUUC-Sbi-114325	Sorghum bicolor	64.36	2.00e-104	371.00
IUUC-Sre-115203	Sporisorium reilianum	59.18	4.00e-81	295.00
IUUC-Ssc-115361	Sus scrofa	89.11	0.00e+00	734.00
IUUC-Tgu-116967	Taeniopygia guttata	73.07	2.00e-151	528.00
IUUC-Tru-117570	Takifugu rubripes	62.53	4.00e-135	474.00
IUUC-Tsy-119280	Tarsius syrichta	92.09	5.00e-118	417.00
IUUC-Tni-120721	Tetraodon nigroviridis	62.05	6.00e-135	473.00
IUUC-Tca-121494	Theobroma cacao	65.17	4.00e-104	370.00
IUUC-Tre-121869	Trichoderma reesei	55.56	3.00e-92	332.00
IUUC-Tvi-122510	Trichoderma virens	57.04	8.00e-92	330.00
IUUC-Tae-123071	Triticum aestivum	62.46	2.00e-103	368.00
IUUC-Tur-126240	Triticum urartu	62.46	6.00e-103	367.00
IUUC-Tme-126921	Tuber melanosporum	59.43	3.00e-96	345.00
IUUC-Tbe-127872	Tupaia belangeri	81.63	0.00e+00	635.00
IUUC-Ttr-129134	Tursiops truncatus	89.92	0.00e+00	698.00
IUUC-Uma-129412	Ustilago maydis	58.43	1.00e-80	293.00
IUUC-Vda-130003	Verticillium dahliae	55.41	4.00e-92	331.00
IUUC-Vvi-131272	Vitis vinifera	61.36	4.00e-105	374.00
IUUC-Xtr-132019	Xenopus tropicalis	64.60	2.00e-149	521.00
IUUC-Xma-134203	Xiphophorus maculatus	60.77	6.00e-134	470.00
IUUC-Yli-134503	Yarrowia lipolytica	54.23	8.00e-87	313.00
IUUC-Zma-135232	Zea mays	65.56	3.00e-104	371.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence