iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000026559.1	ENSSSCT00000032131.1	ENSSSCP00000027088.1
ENSSSCG00000026559.1	ENSSSCT00000028655.1	ENSSSCP00000023098.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-58	192.9	42	81
UBD/Beta-Prp	3.80e-133	443.5	662	880

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvllk 37
           Ht +v claf sd  +l+s + D  +t+ +WD+r+g+ll 
   Q: 42   HTHGVACLAFdSDgQRLASVGLDakNTVCIWDWRKGKLLA 81
           99*********999*******9999***********9875 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ ++ ++++p k+++atg  +rd+ i vwd++t k+l+ l  +h+ +v a++fs dgk lv+++ D  + i  wd ++g+ + t 
   Q: 662  GHDDDILS-LTIHPVKDYVATGqvGRDAAIHVWDTQTLKCLSLLkGQHQRGVCALDFSADGKCLVSVGLDdfHSIVFWDWKKGEKIATT 749
           45555555.999*********95569****************99778999******************9977778889*********** PP
   S: 91   kghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh++++  ++ +p   dklv+ +  + i+ w+   g   ++     + g+ ++ +cv++   ++l++sG++ + + +W  k   ll+t
   Q: 750  RGHKEKIFVVKCNPHHvDKLVTVG-IKHIKFWQQAGGGFTSKrgifGNVGKLETMMCVSYGRMEDLVFSGAATGDIFIW--KDILLLKT 835
           **************7769999887.999****9888888877999888899999********99***************..88999*** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
            +  h+++v  +   +  k +v+g++dg v+lwd   ++c++t+   +
   Q: 836  VKA-HDGPVFAMYALD--KGFVTGGKDGIVELWDDMFERCLKTYAIKR 880
           *98.*****9999888..57****************999*99997555 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

FFSLALHPDK TLVATGQVGK EPYICIWDSY NVQTVSILKD VHTHGVACLA FDSDGQRLAS 60
VGLDAKNTVC IWDWRKGKLL ASATGHSDRI FDISWDPYQP NRVVSCGVKH IKFWTLCGNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTTCAGCC TTGCCTTACA CCCAGATAAA ACTCTTGTTG CAACTGGCCA AGTTGGGAAG 60
GAACCATATA TATGTATATG GGATTCCTAT AATGTCCAAA CTGTGTCTAT TCTTAAAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	98.79	0.00e+00	3774.00
IUUC-Apl-003604	Anas platyrhynchos	94.06	0.00e+00	3594.00
IUUC-Aca-004572	Anolis carolinensis	89.73	0.00e+00	3490.00
IUUC-Ame-010713	Astyanax mexicanus	80.21	0.00e+00	3099.00
IUUC-Bta-012812	Bos taurus	98.68	0.00e+00	3770.00
IUUC-Cja-019191	Callithrix jacchus	97.94	0.00e+00	3755.00
IUUC-Cfa-020041	Canis familiaris	98.76	0.00e+00	3495.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	33.61	2.00e-84	309.00
IUUC-Csa-023689	Chlorocebus sabaeus	97.38	0.00e+00	3736.00
IUUC-Cho-025038	Choloepus hoffmanni	97.39	0.00e+00	1496.00
IUUC-Cin-025205	Ciona intestinalis	61.88	0.00e+00	2479.00
IUUC-Csv-026014	Ciona savignyi	63.12	0.00e+00	2493.00
IUUC-Dno-029982	Dasypus novemcinctus	96.43	0.00e+00	3685.00
IUUC-Eca-034161	Equus caballus	97.05	0.00e+00	3702.00
IUUC-Fca-036307	Felis catus	98.73	0.00e+00	3769.00
IUUC-Fal-037332	Ficedula albicollis	92.86	0.00e+00	3543.00
IUUC-Gmo-039057	Gadus morhua	74.42	0.00e+00	2863.00
IUUC-Gac-042555	Gasterosteus aculeatus	80.06	0.00e+00	3133.00
IUUC-Ggo-045107	Gorilla gorilla	98.05	0.00e+00	3753.00
IUUC-Hsa-046482	Homo sapiens	98.10	0.00e+00	3751.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	96.69	0.00e+00	3742.00
IUUC-Loc-052642	Lepisosteus oculatus	88.06	0.00e+00	3378.00
IUUC-Laf-053649	Loxodonta africana	97.26	0.00e+00	3678.00
IUUC-Mcc-055361	Macaca mulatta	98.14	0.00e+00	3387.00
IUUC-Meu-056618	Macropus eugenii	77.88	0.00e+00	1701.00
IUUC-Mga-059202	Meleagris gallopavo	93.35	0.00e+00	3593.00
IUUC-Mmr-060729	Microcebus murinus	97.95	0.00e+00	3740.00
IUUC-Mdo-062462	Monodelphis domestica	95.88	0.00e+00	3693.00
IUUC-Mmu-063865	Mus musculus	96.83	0.00e+00	3729.00
IUUC-Mpu-066724	Mustela putorius furo	98.94	0.00e+00	3775.00
IUUC-Mlu-067816	Myotis lucifugus	98.32	0.00e+00	3767.00
IUUC-Opr-070213	Ochotona princeps	94.83	0.00e+00	2006.00
IUUC-Ont-071928	Oreochromis niloticus	79.33	0.00e+00	3145.00
IUUC-Oan-073563	Ornithorhynchus anatinus	95.27	0.00e+00	3657.00
IUUC-Ocu-074531	Oryctolagus cuniculus	98.05	0.00e+00	3751.00
IUUC-Ola-086943	Oryzias latipes	79.33	0.00e+00	3152.00
IUUC-Olu-087860	Ostreococcus lucimarinus	39.01	5.00e-118	417.00
IUUC-Oga-088665	Otolemur garnettii	97.06	0.00e+00	3712.00
IUUC-Oar-090429	Ovis aries	98.84	0.00e+00	3774.00
IUUC-Ptr-091168	Pan troglodytes	88.53	0.00e+00	3327.00
IUUC-Pan-092788	Papio anubis	98.01	0.00e+00	3071.00
IUUC-Psi-093281	Pelodiscus sinensis	92.49	0.00e+00	3531.00
IUUC-Pma-094424	Petromyzon marinus	72.46	2.00e-124	437.00
IUUC-Pab-098561	Pongo abelii	97.10	0.00e+00	3242.00
IUUC-Pca-100177	Procavia capensis	86.75	0.00e+00	1545.00
IUUC-Rno-105002	Rattus norvegicus	95.94	0.00e+00	3720.00
IUUC-Sha-107105	Sarcophilus harrisii	93.21	0.00e+00	3568.00
IUUC-Sar-113150	Sorex araneus	98.67	0.00e+00	772.00
IUUC-Tgu-116807	Taeniopygia guttata	93.98	0.00e+00	3587.00
IUUC-Tru-118040	Takifugu rubripes	78.91	0.00e+00	3084.00
IUUC-Tni-120118	Tetraodon nigroviridis	76.14	0.00e+00	3050.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence