iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000011002.1	ENSSHAT00000012965.1	ENSSHAP00000012860.1
ENSSHAG00000011002.1	ENSSHAT00000012966.1	ENSSHAP00000012861.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.80e-07	31.1	359	399

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C +Cl +f   ++ +++l+C+H fh++C+  w     + + + +CP+
   Q: 359  CRLCLKPFclgQH-TRLLSCNHKFHRKCIDDW-----LLNISNSCPI 399
           9*******88544.9*****************.....7999999997 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MPRGLGGGRG NGGGGWSSER RRCVTDCLKR HQDQALSSHM YLLRETGPTG FLMSENEPDG 60
SNYRVFLGDP HTCSCSTFVK GNDLCKHICW ILLKKFKLPR NHEYAFQLGL VEREINELLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGGGAAGG CATAAAGACA AATGACTTTA ATCATGTAGA GACTGAATCA CCGTTAGGGA 60
GACACACCTC CTTACATCAT GTACCCCAAC CCCAGCAAAT GGTGAGTAGA GAAGGAGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR007527--Znf_SWIM
IPR000433--Znf_ZZ

PROSITE

PS50089--ZF_RING_2
PS50966--ZF_SWIM
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF04434--SWIM
PF13639--zf-RING_2
PF00569--ZZ

SMART

SM00184--RING
SM00291--ZnF_ZZ

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001754	Ailuropoda melanoleuca	58.02	0.00e+00	702.00
IUUC-Apl-003359	Anas platyrhynchos	63.08	2.00e-47	180.00
IUUC-Aca-004923	Anolis carolinensis	56.70	3.00e-121	428.00
IUUC-Afl-008716	Aspergillus flavus	30.05	6.00e-16	78.20
IUUC-Ani-009202	Aspergillus nidulans	32.02	1.00e-16	80.10
IUUC-Bta-012456	Bos taurus	57.23	0.00e+00	692.00
IUUC-Cja-019186	Callithrix jacchus	57.56	0.00e+00	672.00
IUUC-Cfa-020604	Canis familiaris	56.71	0.00e+00	635.00
IUUC-Cpo-021774	Cavia porcellus	53.98	0.00e+00	642.00
IUUC-Cre-022861	Chlamydomonas reinhardtii	30.37	5.00e-31	129.00
IUUC-Csa-024126	Chlorocebus sabaeus	59.00	0.00e+00	699.00
IUUC-Cho-024501	Choloepus hoffmanni	66.85	6.00e-142	496.00
IUUC-Cin-025662	Ciona intestinalis	45.32	6.00e-96	343.00
IUUC-Cgl-026506	Colletotrichum gloeosporioides	29.79	8.00e-14	70.90
IUUC-Cne-027076	Cryptococcus neoformans	26.67	5.00e-14	72.40
IUUC-Dre-028700	Danio rerio	46.17	7.00e-113	400.00
IUUC-Dno-030007	Dasypus novemcinctus	57.70	0.00e+00	697.00
IUUC-Dor-030562	Dipodomys ordii	48.47	7.00e-113	400.00
IUUC-Dse-031237	Dothistroma septosporum	29.78	2.00e-11	63.20
IUUC-Ete-032603	Echinops telfairi	62.36	9.00e-127	446.00
IUUC-Eca-033283	Equus caballus	61.01	0.00e+00	731.00
IUUC-Eeu-034619	Erinaceus europaeus	52.35	0.00e+00	627.00
IUUC-Fca-035573	Felis catus	58.65	0.00e+00	721.00
IUUC-Fso-038137	Fusarium solani	27.07	2.00e-11	63.20
IUUC-Ggr-039924	Gaeumannomyces graminis	27.04	4.00e-11	62.00
IUUC-Ggo-045207	Gorilla gorilla	59.16	0.00e+00	707.00
IUUC-Hsa-046776	Homo sapiens	59.16	0.00e+00	702.00
IUUC-Itr-048416	Ictidomys tridecemlineatus	57.41	0.00e+00	692.00
IUUC-Lch-050394	Latimeria chalumnae	53.48	1.00e-142	499.00
IUUC-Loc-052123	Lepisosteus oculatus	52.64	8.00e-134	470.00
IUUC-Lma-053033	Leptosphaeria maculans	33.97	1.00e-13	70.10
IUUC-Laf-053456	Loxodonta africana	57.73	0.00e+00	686.00
IUUC-Mcc-055227	Macaca mulatta	58.84	0.00e+00	696.00
IUUC-Meu-055957	Macropus eugenii	81.47	3.00e-121	428.00
IUUC-Mmr-061710	Microcebus murinus	57.95	0.00e+00	701.00
IUUC-Mdo-062378	Monodelphis domestica	76.86	0.00e+00	964.00
IUUC-Mmu-064269	Mus musculus	53.62	0.00e+00	633.00
IUUC-Mpu-066736	Mustela putorius furo	55.96	0.00e+00	634.00
IUUC-Mlu-067142	Myotis lucifugus	50.86	1.00e-156	546.00
IUUC-Nfi-068477	Neosartorya fischeri	28.95	2.00e-14	73.20
IUUC-Ncr-068657	Neurospora crassa	30.07	2.00e-11	62.80
IUUC-Nle-069268	Nomascus leucogenys	58.11	0.00e+00	707.00
IUUC-Opr-071154	Ochotona princeps	45.49	2.00e-97	350.00
IUUC-Oan-072878	Ornithorhynchus anatinus	37.46	1.00e-46	180.00
IUUC-Ocu-074017	Oryctolagus cuniculus	56.41	1.00e-180	625.00
IUUC-Oga-088906	Otolemur garnettii	54.25	3.00e-180	624.00
IUUC-Oar-089422	Ovis aries	57.46	0.00e+00	699.00
IUUC-Ptr-090772	Pan troglodytes	58.36	0.00e+00	691.00
IUUC-Pan-092838	Papio anubis	59.00	0.00e+00	686.00
IUUC-Psi-093288	Pelodiscus sinensis	58.58	2.00e-152	531.00
IUUC-Pma-094709	Petromyzon marinus	47.28	3.00e-108	384.00
IUUC-Pfo-096189	Poecilia formosa	41.44	2.00e-94	339.00
IUUC-Pab-098389	Pongo abelii	54.34	3.00e-179	621.00
IUUC-Pca-100376	Procavia capensis	52.13	3.00e-169	588.00
IUUC-Pva-102163	Pteropus vampyrus	57.14	0.00e+00	659.00
IUUC-Pte-104391	Pyrenophora teres	33.16	1.00e-14	73.90
IUUC-Pyt-104706	Pyrenophora triticirepentis	33.97	2.00e-13	70.10
IUUC-Rno-105988	Rattus norvegicus	54.25	0.00e+00	657.00
IUUC-Sar-113069	Sorex araneus	54.93	0.00e+00	646.00
IUUC-Ssc-116112	Sus scrofa	54.29	2.00e-177	615.00
IUUC-Tsy-118825	Tarsius syrichta	60.48	3.00e-175	607.00
IUUC-Tbe-127891	Tupaia belangeri	55.43	0.00e+00	662.00
IUUC-Ttr-129130	Tursiops truncatus	56.17	3.00e-173	601.00
IUUC-Vda-129853	Verticillium dahliae	26.82	1.00e-11	63.50
IUUC-Vpa-130753	Vicugna pacos	57.72	0.00e+00	692.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence