iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035803

Ensembl Protein ID

ENSFCAP00000023963.1

UniProt Accession

M3XBF9; M3XBF9_FELCA

Genbank Protein ID

ENSFCAP00000023963

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02189940

Gene Name

UBQLN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000014297.2	ENSFCAT00000014301.2	ENSFCAP00000023963.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.70e-10	40.7	581	618
ULD/UDP/UBQ/UBQ_PIM	2.00e-23	82.2	33	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 581  FQQQLEQLNAMGFlNREANLQALIATGGDINAAIERLL 618
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +k+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tL ++gi+dg +vhlv+k ++
   Q: 33   IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQN 106
           69**********.***********************************************************986 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MAENGESSGP PRPSRGPAAA QGPASAPAEP KIIKVTVKTP KEKEEFAVPE NSSVQQFKEA 60
ISKRFKSQTD QLVLIFAGKI LKDQDTLIQH GIHDGLTVHL VIKSQNRPQG QSTQPSNAAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA ACGGCGAGAG TAGCGGCCCC CCGCGCCCCT CCCGCGGCCC TGCTGCAGCC 60
CAAGGCCCTG CCTCTGCCCC GGCCGAGCCA AAAATCATCA AAGTCACTGT GAAGACCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:1900186--P:negative regulation of clathrin-dependent endocytosis
GO:1904021--P:negative regulation of G-protein coupled receptor internalization
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

fca:101097874

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Afu-009029	Aspergillus fumigatus	33.75	4.00e-07	49.30
IUUC-Bta-013571	Bos taurus	98.36	0.00e+00	633.00
IUUC-Cfa-020799	Canis familiaris	99.10	0.00e+00	634.00
IUUC-Cpo-022093	Cavia porcellus	91.20	6.00e-172	597.00
IUUC-Cre-022634	Chlamydomonas reinhardtii	48.15	3.00e-11	62.80
IUUC-Csa-023627	Chlorocebus sabaeus	92.76	0.00e+00	747.00
IUUC-Cho-024552	Choloepus hoffmanni	92.58	5.00e-173	600.00
IUUC-Dno-029647	Dasypus novemcinctus	91.60	1.00e-179	623.00
IUUC-Ete-033071	Echinops telfairi	87.99	0.00e+00	732.00
IUUC-Eeu-034727	Erinaceus europaeus	94.47	1.00e-175	609.00
IUUC-Hsa-046768	Homo sapiens	97.97	1.00e-177	616.00
IUUC-Hvu-047094	Hordeum vulgare	50.98	5.00e-09	53.10
IUUC-Itr-048556	Ictidomys tridecemlineatus	91.70	2.00e-173	602.00
IUUC-Mmr-061605	Microcebus murinus	96.84	2.00e-170	592.00
IUUC-Mpu-066474	Mustela putorius furo	99.10	0.00e+00	627.00
IUUC-Mlu-067252	Myotis lucifugus	88.31	7.00e-165	573.00
IUUC-Nfi-068487	Neosartorya fischeri	33.75	2.00e-07	50.10
IUUC-Ncr-068732	Neurospora crassa	48.98	2.00e-07	50.10
IUUC-Nle-069038	Nomascus leucogenys	97.97	3.00e-178	618.00
IUUC-Oga-088005	Otolemur garnettii	97.52	2.00e-177	615.00
IUUC-Oar-089878	Ovis aries	95.99	0.00e+00	762.00
IUUC-Ptr-090781	Pan troglodytes	97.97	4.00e-178	617.00
IUUC-Pan-091716	Papio anubis	90.21	0.00e+00	689.00
IUUC-Pab-097891	Pongo abelii	98.19	8.00e-178	616.00
IUUC-Pca-100227	Procavia capensis	96.20	2.00e-93	336.00
IUUC-Pgr-103261	Puccinia graminis	54.76	2.00e-07	50.10
IUUC-Tsy-119008	Tarsius syrichta	94.91	5.00e-166	577.00
IUUC-Vda-129991	Verticillium dahliae	46.15	8.00e-07	48.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence