iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055267

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03010535

Gene Name

BIRC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000009367.3	ENSMMUT00000013092.3	ENSMMUP00000012271.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.70e-34	117.7	4599	4755

Active Site

Position(s)	Description	Evidence
4688	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp....egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.....ifhPnvyen 78
           Rl++e+ +l+++ p    +++++++++e  l+ ++vli+Gp+dtpY++g+F+++++fp+dYP++PP v+++t+     +f+Pn+y++
   Q: 4599 RLAQEAVTLSTSLPlsssSSVFVRCDEE-RLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTgghsvRFNPNLYND 4684
           8999999999998877768899999999.6********************************************************* PP
   S: 79   GkvClsilk.....eeekWsp.alsvesvllsiqsll..aepnpesplneeaa...ellkknreeykkkvre 139
           GkvClsil+     +eekW+p ++s+ +vl+s+qsl+  aep++++p +e+++   + ++++re y+ ++r+
   Q: 4685 GKVCLSILNtwhgrPEEKWNPqTSSFLQVLVSVQSLIlvAEPYFNEPGYERSRgtpSGTQSSRE-YDGNIRQ 4755
           ********7788889******8899***********999***********99866555666655.9998875 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MVTGGGAAPP GTVTEPLPSV IVLSAGRKMA AAAAAASGPG CSSAAGSGAA GVSEWLVLRD 60
GCMHCDADGL HSLSYHPALN AILAVTSRGT IKVIDGTSGA TLQASALSGE YPGKEAAQPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGACTG GCGGTGGTGC TGCACCTCCC GGGACTGTCA CTGAGCCGCT TCCCAGTGTG 60
ATTGTGCTGA GCGCAGGCCG GAAGATGGCG GCTGCGGCTG CGGCGGCCTC GGGCCCCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001370--BIR_rpt
IPR022103--BIRC6
IPR008979--Galactose-bd-like
IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50143--BIR_REPEAT_2
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00653--BIR
PF12356--BIRC6
PF00179--UQ_con

SMART

SM00238--BIR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005768--C:endosome
GO:0016020--C:membrane
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0000922--C:spindle pole
GO:0005802--C:trans-Golgi network
GO:0004869--F:cysteine-type endopeptidase inhibitor activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006915--P:apoptotic process
GO:0060711--P:labyrinthine layer development
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0008284--P:positive regulation of cell proliferation
GO:0032465--P:regulation of cytokinesis
GO:0009966--P:regulation of signal transduction
GO:0060712--P:spongiotrophoblast layer development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001583	Ailuropoda melanoleuca	97.43	0.00e+00	8771.00
IUUC-Atr-003108	Amborella trichopoda	42.86	4.00e-45	175.00
IUUC-Apl-004144	Anas platyrhynchos	92.50	0.00e+00	5653.00
IUUC-Aca-005257	Anolis carolinensis	89.88	0.00e+00	8101.00
IUUC-Ath-007217	Arabidopsis thaliana	37.08	7.00e-44	172.00
IUUC-Ani-009463	Aspergillus nidulans	41.78	9.00e-28	117.00
IUUC-Ame-011337	Astyanax mexicanus	78.11	0.00e+00	6719.00
IUUC-Bta-012501	Bos taurus	96.43	0.00e+00	8569.00
IUUC-Bci-013596	Botrytis cinerea	36.99	8.00e-23	101.00
IUUC-Bdi-014931	Brachypodium distachyon	38.06	3.00e-46	179.00
IUUC-Bol-015976	Brassica oleracea	46.33	1.00e-45	177.00
IUUC-Bra-017967	Brassica rapa	46.33	5.00e-46	178.00
IUUC-Cel-018661	Caenorhabditis elegans	36.14	4.00e-79	289.00
IUUC-Cja-018746	Callithrix jacchus	98.34	0.00e+00	8787.00
IUUC-Cfa-020170	Canis familiaris	97.67	0.00e+00	8595.00
IUUC-Cpo-022138	Cavia porcellus	97.12	0.00e+00	5825.00
IUUC-Cre-022768	Chlamydomonas reinhardtii	44.69	1.00e-44	172.00
IUUC-Csa-023927	Chlorocebus sabaeus	99.22	0.00e+00	8826.00
IUUC-Cho-024890	Choloepus hoffmanni	94.61	0.00e+00	1946.00
IUUC-Cgl-026412	Colletotrichum gloeosporioides	39.04	4.00e-24	105.00
IUUC-Cne-026995	Cryptococcus neoformans	42.62	2.00e-37	150.00
IUUC-Dre-027941	Danio rerio	78.58	0.00e+00	5353.00
IUUC-Dno-028913	Dasypus novemcinctus	95.43	0.00e+00	8553.00
IUUC-Dor-030715	Dipodomys ordii	95.02	0.00e+00	1954.00
IUUC-Dse-031232	Dothistroma septosporum	44.51	4.00e-38	153.00
IUUC-Dme-031592	Drosophila melanogaster	52.78	0.00e+00	672.00
IUUC-Ete-032587	Echinops telfairi	77.96	0.00e+00	2079.00
IUUC-Eca-033819	Equus caballus	97.43	0.00e+00	8665.00
IUUC-Eeu-034863	Erinaceus europaeus	85.83	0.00e+00	2538.00
IUUC-Fca-035505	Felis catus	94.61	0.00e+00	8385.00
IUUC-Fal-037318	Ficedula albicollis	92.51	0.00e+00	8291.00
IUUC-Fox-037961	Fusarium oxysporum	37.67	4.00e-22	99.40
IUUC-Fso-038352	Fusarium solani	36.99	6.00e-21	95.50
IUUC-Gmo-039521	Gadus morhua	81.35	0.00e+00	1690.00
IUUC-Ggr-040040	Gaeumannomyces graminis	47.06	2.00e-33	138.00
IUUC-Gga-040728	Gallus gallus	92.36	0.00e+00	8204.00
IUUC-Gac-042251	Gasterosteus aculeatus	84.57	0.00e+00	1793.00
IUUC-Ggo-045562	Gorilla gorilla	97.43	0.00e+00	1625.00
IUUC-Hsa-046339	Homo sapiens	99.08	0.00e+00	8742.00
IUUC-Hvu-047441	Hordeum vulgare	46.70	4.00e-47	182.00
IUUC-Itr-048099	Ictidomys tridecemlineatus	97.85	0.00e+00	2717.00
IUUC-Lch-050164	Latimeria chalumnae	85.37	0.00e+00	7516.00
IUUC-Lpe-051294	Leersia perrieri	40.23	3.00e-47	182.00
IUUC-Loc-052800	Lepisosteus oculatus	85.11	0.00e+00	7558.00
IUUC-Lma-053044	Leptosphaeria maculans	39.73	8.00e-26	111.00
IUUC-Laf-054034	Loxodonta africana	96.18	0.00e+00	8603.00
IUUC-Meu-056461	Macropus eugenii	93.15	0.00e+00	1239.00
IUUC-Mor-057074	Magnaporthe oryzae	37.67	6.00e-18	85.10
IUUC-Mpo-057396	Magnaporthe poae	49.03	2.00e-34	141.00
IUUC-Mtr-057797	Medicago truncatula	39.52	3.00e-47	182.00
IUUC-Mla-059114	Melampsora laricipopulina	28.31	5.00e-40	159.00
IUUC-Mga-059594	Meleagris gallopavo	92.06	0.00e+00	7767.00
IUUC-Mmr-061179	Microcebus murinus	98.01	0.00e+00	8702.00
IUUC-Mdo-062990	Monodelphis domestica	93.88	0.00e+00	8267.00
IUUC-Mmu-063825	Mus musculus	95.09	0.00e+00	8490.00
IUUC-Mpu-065908	Mustela putorius furo	97.55	0.00e+00	5580.00
IUUC-Mlu-067106	Myotis lucifugus	96.03	0.00e+00	8586.00
IUUC-Ncr-068852	Neurospora crassa	34.81	1.00e-17	84.30
IUUC-Nle-069347	Nomascus leucogenys	99.08	0.00e+00	8793.00
IUUC-Opr-070799	Ochotona princeps	87.38	0.00e+00	2547.00
IUUC-Ont-072046	Oreochromis niloticus	79.10	0.00e+00	6783.00
IUUC-Oan-073415	Ornithorhynchus anatinus	93.50	0.00e+00	3416.00
IUUC-Ocu-074556	Oryctolagus cuniculus	97.21	0.00e+00	8616.00
IUUC-Oba-075870	Oryza barthii	39.31	2.00e-47	183.00
IUUC-Obr-076463	Oryza brachyantha	38.81	7.00e-47	181.00
IUUC-Ogl-077040	Oryza glaberrima	39.55	5.00e-40	159.00
IUUC-Ogu-077966	Oryza glumaepatula	39.31	1.00e-47	183.00
IUUC-Oin-079561	Oryza indica	39.55	4.00e-40	159.00
IUUC-Olo-080416	Oryza longistaminata	41.04	1.00e-40	162.00
IUUC-Ome-081384	Oryza meridionalis	39.55	6.00e-40	158.00
IUUC-Oni-082241	Oryza nivara	39.55	5.00e-40	159.00
IUUC-Opu-083659	Oryza punctata	38.81	2.00e-46	180.00
IUUC-Oru-085077	Oryza rufipogon	39.31	2.00e-47	183.00
IUUC-Osa-085920	Oryza sativa	39.55	4.00e-40	159.00
IUUC-Ola-087459	Oryzias latipes	82.73	0.00e+00	2879.00
IUUC-Oga-088251	Otolemur garnettii	95.20	0.00e+00	8236.00
IUUC-Oar-090367	Ovis aries	96.80	0.00e+00	8634.00
IUUC-Ptr-091512	Pan troglodytes	99.08	0.00e+00	8794.00
IUUC-Pan-092222	Papio anubis	98.09	0.00e+00	8752.00
IUUC-Pma-094574	Petromyzon marinus	60.87	0.00e+00	2994.00
IUUC-Ppa-095592	Physcomitrella patens	29.45	4.00e-55	209.00
IUUC-Pfo-097086	Poecilia formosa	78.01	0.00e+00	6836.00
IUUC-Pab-098390	Pongo abelii	97.31	0.00e+00	8549.00
IUUC-Pop-099284	Populus trichocarpa	37.75	3.00e-42	166.00
IUUC-Pca-101036	Procavia capensis	88.65	0.00e+00	4124.00
IUUC-Ppe-101722	Prunus persica	44.51	4.00e-43	169.00
IUUC-Pva-103053	Pteropus vampyrus	92.36	0.00e+00	3596.00
IUUC-Pte-104333	Pyrenophora teres	41.29	1.00e-43	172.00
IUUC-Pyt-104498	Pyrenophora triticirepentis	39.39	4.00e-44	173.00
IUUC-Rno-106049	Rattus norvegicus	95.38	0.00e+00	6956.00
IUUC-Sha-107483	Sarcophilus harrisii	90.78	0.00e+00	7774.00
IUUC-Smo-108915	Selaginella moellendorffii	42.96	2.00e-44	172.00
IUUC-Sly-110929	Solanum lycopersicum	38.55	2.00e-46	180.00
IUUC-Stu-112554	Solanum tuberosum	38.96	1.00e-46	181.00
IUUC-Sar-112965	Sorex araneus	86.29	0.00e+00	1808.00
IUUC-Sbi-113880	Sorghum bicolor	35.99	2.00e-44	174.00
IUUC-Ssc-115927	Sus scrofa	97.67	0.00e+00	6002.00
IUUC-Tgu-117132	Taeniopygia guttata	92.20	0.00e+00	8191.00
IUUC-Tru-118115	Takifugu rubripes	75.71	0.00e+00	6658.00
IUUC-Tsy-118899	Tarsius syrichta	95.06	0.00e+00	5087.00
IUUC-Tni-120891	Tetraodon nigroviridis	74.62	0.00e+00	6620.00
IUUC-Tre-121946	Trichoderma reesei	37.84	6.00e-22	98.60
IUUC-Tvi-122513	Trichoderma virens	39.19	4.00e-23	102.00
IUUC-Tae-125407	Triticum aestivum	47.25	3.00e-47	182.00
IUUC-Tur-126479	Triticum urartu	46.41	2.00e-43	170.00
IUUC-Tme-126930	Tuber melanosporum	42.60	7.00e-48	186.00
IUUC-Tbe-127630	Tupaia belangeri	94.41	0.00e+00	1560.00
IUUC-Ttr-128629	Tursiops truncatus	95.30	0.00e+00	8469.00
IUUC-Vda-129728	Verticillium dahliae	37.67	1.00e-18	87.80
IUUC-Vpa-130310	Vicugna pacos	96.58	0.00e+00	8346.00
IUUC-Xtr-131861	Xenopus tropicalis	83.51	0.00e+00	7266.00
IUUC-Xma-133613	Xiphophorus maculatus	77.94	0.00e+00	6792.00
IUUC-Zma-135768	Zea mays	35.90	3.00e-45	177.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence