iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000008176.2	ENSSSCT00000023061.1	ENSSSCP00000023488.1
ENSSSCG00000008176.2	ENSSSCT00000008954.2	ENSSSCP00000008728.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-07	32.3	474	512
E3 activity/RING/U-box	3.50e-09	36.9	470	517

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C+  +++ p+++pCgH+f+++Cl++          + +CPlC+
   Q: 474  CALCMRLLFE-PVTTPCGHTFCLKCLERC------LDHAPHCPLCK 512
           **********.9**************999......9*********7 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           ++f C++ + l  +Pv++p+G+t+  +++e++l++  + cP+++++l+e
   Q: 470  ADFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPH-CPLCKEKLSE 517
           58************************************.********76 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

RRRPAVMSPE PVPPPPPPPQ CRGCDGGEPL AQRVEKGDEA FRAGEYETAA ELFRSALAGL 60
AQPDRGLCLR LGDALARAGR LPEALGAFRG AGRLGVLRPD ELGELAGGLA RALGPRERQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGTGGTCT AGCGGCCCGG AGCGCACCGC CCCCAGACGC GCGTGGCCCT CGGCGGAGGC 60
GGCGGTTCCC AGGTGCAGAG TGTTCTGCGT CCTCCGCTCT TCCCTCCTGG CCTAGTCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00028--TPR

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001867	Ailuropoda melanoleuca	77.31	7.00e-165	573.00
IUUC-Cja-019041	Callithrix jacchus	67.03	6.00e-174	603.00
IUUC-Cfa-020025	Canis familiaris	76.56	9.00e-175	607.00
IUUC-Cre-022730	Chlamydomonas reinhardtii	76.00	5.00e-08	51.20
IUUC-Eeu-034779	Erinaceus europaeus	58.65	2.00e-93	335.00
IUUC-Fca-036276	Felis catus	76.92	2.00e-168	585.00
IUUC-Ggo-045501	Gorilla gorilla	72.73	0.00e+00	674.00
IUUC-Hsa-046630	Homo sapiens	72.27	0.00e+00	673.00
IUUC-Laf-054421	Loxodonta africana	51.31	3.00e-132	465.00
IUUC-Mpu-065764	Mustela putorius furo	75.14	0.00e+00	662.00
IUUC-Nle-069616	Nomascus leucogenys	73.20	0.00e+00	683.00
IUUC-Oga-088972	Otolemur garnettii	72.85	0.00e+00	650.00
IUUC-Pan-092180	Papio anubis	72.83	0.00e+00	686.00
IUUC-Pab-097974	Pongo abelii	72.64	0.00e+00	674.00
IUUC-Pva-102269	Pteropus vampyrus	72.61	0.00e+00	699.00
IUUC-Tvi-122557	Trichoderma virens	25.56	2.00e-04	40.00
IUUC-Ttr-128666	Tursiops truncatus	80.34	0.00e+00	780.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence