• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Spo-108074
Ensembl Protein ID SPCC548.04.1:pep
UniProt Accession Q9P3U9; URM1_SCHPO
Genbank Protein ID CAB94946.2
Protein Name Ubiquitin-related modifier 1
Genbank Nucleotide ID CU329672
Gene Name urm1; SPCC548.04
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPCC548.04 SPCC548.04.1 SPCC548.04.1:pep
Annotation
mRNA Expression
GEO
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UBQ/UBQ_Other 44.79 6.00e-15 73.60 IUUC-Sce-106366
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
 Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Protein Sequence
(Fasta)
MAIKVELLGG LDLLFNKQKA LSLSLSNLGS TKLGSLIDYM AQIIEKPSQK DLFILNGTVR 60
PGIIVLVNDQ DWELLEKEEY NLEEGDEVVF VSTLHGG 97
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108074|ULD,UBQ_Other|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAACTGCGTA GCTGACATGA CACTGAATTT CTATCACTCT TTAACAACTA CAGTGGAATA 60
TACAGTTAGA ACGTACATTT TGCGTTGCTT TCACGAATCC CCAAAGTTTT AAAAAACAAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108074|ULD,UBQ_Other|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-1185--Reference proteome
KW-0819--tRNA processing
KW-0833--Ubl conjugation pathway
Interpro

IPR012675--Beta-grasp_dom
IPR016155--Mopterin_synth/thiamin_S_b
IPR015221--Urm1
Pfam

PF09138--Urm1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0031386--F:protein tag
GO:0032447--P:protein urmylation
GO:0002143--P:tRNA wobble position uridine thiolation
KEGG spo:SPCC548.04
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002254 Ailuropoda melanoleuca 39.80 4.00e-14 67.40
IUUC-Atr-003089 Amborella trichopoda 40.59 3.00e-14 67.80
IUUC-Apl-003382 Anas platyrhynchos 38.89 3.00e-12 61.20
IUUC-Aca-004981 Anolis carolinensis 37.76 2.00e-13 65.10
IUUC-Aly-005517 Arabidopsis lyrata 38.30 3.00e-12 60.80
IUUC-Ath-006718 Arabidopsis thaliana 52.73 8.00e-12 59.70
IUUC-Ago-007917 Ashbya gossypii 47.47 1.00e-19 85.90
IUUC-Acl-008054 Aspergillus clavatus 61.54 2.00e-15 70.90
IUUC-Afl-008704 Aspergillus flavus 53.23 3.00e-16 73.90
IUUC-Aor-009890 Aspergillus oryzae 42.57 1.00e-18 82.80
IUUC-Bta-012448 Bos taurus 40.82 1.00e-14 68.90
IUUC-Bci-013865 Botrytis cinerea 44.55 1.00e-19 85.90
IUUC-Bdi-014980 Brachypodium distachyon 52.73 1.00e-11 59.30
IUUC-Bol-016055 Brassica oleracea 54.55 5.00e-12 60.50
IUUC-Bra-016845 Brassica rapa 54.55 5.00e-12 60.50
IUUC-Cel-018485 Caenorhabditis elegans 51.28 1.00e-06 42.70
IUUC-Cja-019587 Callithrix jacchus 38.78 5.00e-14 67.00
IUUC-Cfa-020653 Canis familiaris 39.80 2.00e-14 68.60
IUUC-Cpo-021622 Cavia porcellus 38.78 5.00e-14 67.00
IUUC-Cre-023015 Chlamydomonas reinhardtii 42.57 1.00e-15 72.40
IUUC-Csa-023756 Chlorocebus sabaeus 35.53 5.00e-07 44.70
IUUC-Cgl-026518 Colletotrichum gloeosporioides 39.60 6.00e-19 83.60
IUUC-Cne-026953 Cryptococcus neoformans 35.58 2.00e-12 62.80
IUUC-Cme-027314 Cyanidioschyzon merolae 40.00 4.00e-13 63.90
IUUC-Dre-027884 Danio rerio 38.78 3.00e-13 64.30
IUUC-Dno-029262 Dasypus novemcinctus 35.53 9.00e-07 44.30
IUUC-Dor-030601 Dipodomys ordii 48.98 1.00e-07 45.80
IUUC-Dme-031893 Drosophila melanogaster 41.41 2.00e-14 68.60
IUUC-Ete-032773 Echinops telfairi 58.49 1.00e-13 65.90
IUUC-Eca-034187 Equus caballus 37.76 7.00e-14 66.60
IUUC-Eeu-034808 Erinaceus europaeus 39.80 2.00e-14 68.20
IUUC-Fca-036107 Felis catus 38.78 6.00e-14 67.00
IUUC-Fal-036607 Ficedula albicollis 37.78 2.00e-12 61.60
IUUC-Fox-037698 Fusarium oxysporum 44.55 8.00e-20 86.70
IUUC-Gmo-039492 Gadus morhua 41.11 5.00e-13 63.50
IUUC-Ggr-039965 Gaeumannomyces graminis 43.56 6.00e-19 84.30
IUUC-Gga-041268 Gallus gallus 38.78 4.00e-14 67.40
IUUC-Gac-042111 Gasterosteus aculeatus 41.00 2.00e-14 68.60
IUUC-Gma-043240 Glycine max 54.55 9.00e-12 59.70
IUUC-Ggo-045176 Gorilla gorilla 34.62 3.00e-07 45.40
IUUC-Hsa-046077 Homo sapiens 38.00 3.00e-14 67.80
IUUC-Itr-048111 Ictidomys tridecemlineatus 54.72 1.00e-12 62.00
IUUC-Kpa-049157 Komagataella pastoris 37.76 1.00e-15 72.40
IUUC-Lch-049889 Latimeria chalumnae 40.82 2.00e-14 68.90
IUUC-Lpe-050783 Leersia perrieri 51.85 6.00e-11 57.00
IUUC-Loc-052400 Lepisosteus oculatus 58.49 1.00e-13 65.90
IUUC-Lma-053259 Leptosphaeria maculans 42.57 9.00e-20 86.30
IUUC-Laf-053596 Loxodonta africana 40.00 4.00e-14 67.40
IUUC-Mcc-054845 Macaca mulatta 56.60 6.00e-13 63.50
IUUC-Meu-055968 Macropus eugenii 37.76 3.00e-13 64.30
IUUC-Mor-057126 Magnaporthe oryzae 45.45 7.00e-19 84.00
IUUC-Mpo-057311 Magnaporthe poae 46.53 2.00e-21 92.40
IUUC-Mtr-058266 Medicago truncatula 56.36 3.00e-12 61.20
IUUC-Mla-058847 Melampsora laricipopulina 43.00 2.00e-14 68.90
IUUC-Mga-059468 Meleagris gallopavo 40.00 5.00e-13 63.50
IUUC-Mvi-060235 Microbotryum violaceum 48.53 1.00e-14 70.10
IUUC-Mdo-061948 Monodelphis domestica 37.76 3.00e-13 64.30
IUUC-Mmu-063946 Mus musculus 38.78 3.00e-14 68.20
IUUC-Mac-064812 Musa acuminata 52.73 5.00e-12 60.50
IUUC-Mpu-066763 Mustela putorius furo 37.76 2.00e-13 65.50
IUUC-Mlu-066970 Myotis lucifugus 35.53 3.00e-07 43.90
IUUC-Ncr-068824 Neurospora crassa 42.42 6.00e-20 87.00
IUUC-Nle-069849 Nomascus leucogenys 35.53 5.00e-07 44.70
IUUC-Opr-070227 Ochotona princeps 38.78 5.00e-14 67.00
IUUC-Ont-072530 Oreochromis niloticus 40.82 8.00e-15 69.70
IUUC-Oan-073191 Ornithorhynchus anatinus 37.76 3.00e-13 64.70
IUUC-Ocu-074460 Oryctolagus cuniculus 38.78 6.00e-14 66.60
IUUC-Oba-075499 Oryza barthii 52.73 2.00e-11 59.30
IUUC-Obr-076896 Oryza brachyantha 52.73 9.00e-12 61.60
IUUC-Ogl-077834 Oryza glaberrima 52.73 1.00e-11 58.90
IUUC-Ogu-078622 Oryza glumaepatula 52.73 1.00e-11 58.90
IUUC-Oin-079358 Oryza indica 52.73 3.00e-11 59.30
IUUC-Olo-081035 Oryza longistaminata 52.73 1.00e-11 60.10
IUUC-Oni-082425 Oryza nivara 52.73 1.00e-11 58.90
IUUC-Opu-083461 Oryza punctata 51.85 1.00e-10 57.00
IUUC-Oru-084875 Oryza rufipogon 49.15 3.00e-11 57.40
IUUC-Oga-089128 Otolemur garnettii 37.76 9.00e-14 66.20
IUUC-Oar-089896 Ovis aries 40.82 1.00e-14 68.90
IUUC-Ptr-091618 Pan troglodytes 34.62 3.00e-07 45.40
IUUC-Pan-092238 Papio anubis 35.53 6.00e-07 44.70
IUUC-Psi-093879 Pelodiscus sinensis 41.84 3.00e-15 71.20
IUUC-Pma-094484 Petromyzon marinus 58.49 1.00e-12 62.40
IUUC-Ppa-095801 Physcomitrella patens 47.76 1.00e-13 65.90
IUUC-Pfo-097192 Poecilia formosa 38.78 2.00e-13 65.10
IUUC-Pab-098203 Pongo abelii 38.00 5.00e-14 67.00
IUUC-Pop-099614 Populus trichocarpa 54.55 7.00e-12 60.10
IUUC-Pca-100507 Procavia capensis 36.84 2.00e-07 44.70
IUUC-Ppe-101174 Prunus persica 40.20 1.00e-13 65.90
IUUC-Pva-102735 Pteropus vampyrus 39.18 7.00e-14 66.60
IUUC-Pgr-103510 Puccinia graminis 40.00 8.00e-13 63.50
IUUC-Ptt-103918 Puccinia triticina 40.00 7.00e-13 63.50
IUUC-Pte-104173 Pyrenophora teres 40.59 3.00e-18 81.30
IUUC-Pyt-104806 Pyrenophora triticirepentis 40.59 5.00e-18 80.50
IUUC-Rno-105820 Rattus norvegicus 37.76 1.00e-13 65.90
IUUC-Sce-106366 Saccharomyces cerevisiae 44.79 3.00e-20 87.80
IUUC-Sja-107727 Schizosaccharomyces japonicus 61.46 2.00e-27 111.00
IUUC-Smo-108944 Selaginella moellendorffii 40.45 2.00e-12 61.60
IUUC-Sit-110277 Setaria italica 52.73 1.00e-11 59.30
IUUC-Sly-111505 Solanum lycopersicum 56.36 3.00e-12 61.20
IUUC-Stu-112076 Solanum tuberosum 56.36 3.00e-12 61.20
IUUC-Sbi-114274 Sorghum bicolor 47.76 7.00e-12 60.50
IUUC-Sre-114953 Sporisorium reilianum 38.24 1.00e-13 66.20
IUUC-Ssc-115418 Sus scrofa 37.76 1.00e-13 66.20
IUUC-Tgu-117311 Taeniopygia guttata 37.78 2.00e-12 61.60
IUUC-Tru-118598 Takifugu rubripes 42.22 4.00e-13 63.50
IUUC-Tni-120109 Tetraodon nigroviridis 40.40 2.00e-12 61.60
IUUC-Tca-120942 Theobroma cacao 54.55 6.00e-12 60.10
IUUC-Tre-122099 Trichoderma reesei 46.24 1.00e-14 69.30
IUUC-Tvi-122285 Trichoderma virens 43.56 2.00e-15 72.00
IUUC-Tae-125193 Triticum aestivum 50.91 1.00e-11 58.90
IUUC-Tur-126677 Triticum urartu 60.53 2.00e-09 52.00
IUUC-Tme-127120 Tuber melanosporum 41.58 6.00e-20 87.00
IUUC-Tbe-128050 Tupaia belangeri 63.16 7.00e-11 56.60
IUUC-Ttr-129019 Tursiops truncatus 38.14 1.00e-14 68.90
IUUC-Uma-129483 Ustilago maydis 38.24 3.00e-13 64.70
IUUC-Vda-129690 Verticillium dahliae 38.64 2.00e-13 65.50
IUUC-Vvi-131174 Vitis vinifera 52.73 9.00e-12 59.30
IUUC-Xma-133862 Xiphophorus maculatus 38.78 2.00e-13 65.10
IUUC-Yli-134398 Yarrowia lipolytica 36.36 1.00e-13 65.90
IUUC-Zma-134964 Zea mays 52.73 2.00e-11 58.50
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved