iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052218

Ensembl Protein ID

ENSLOCP00000015313.1

UniProt Accession

W5N3V4; W5N3V4_LEPOC

Genbank Protein ID

ENSLOCP00000015313

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01002531

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000012433.1	ENSLOCT00000015342.1	ENSLOCP00000015313.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.50e-105	352.7	746	1083

Active Site

Position(s)	Description	Evidence
1051	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p  ++ + +   +++++flGr+lgkal++
   Q: 746  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKTGFNPNQGFFKTTNEGLLYPSPTAQMLVGD-SFTRHYYFLGRILGKALYE 831
           689**********99**9*********************************************9965.9****************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++++f+++llg+  ++++++l+++dpe+y++l ++k++ e d+eelgl++t+   ++ lge++++eLk gG++ipVt +N
   Q: 832  NMLVELPFASFFLSKLLGTsaDVDIHHLASLDPEMYRNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKLGGKDIPVTTAN 915
           ******************9666889******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i+ ++ afr+G+ +v++le+l++F+++el++li+G    i++edlkk+t+y ggy++++p+i+ Fwev+e+
   Q: 916  RIAYIHLVADYRLNKQIRPHCLAFRQGLANVVNLEWLRMFDQQELQVLISGAhIPISLEDLKKFTNYSGGYSATHPVIKIFWEVVES 1002
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd +rlP+++TC+n+LkLPe+  +  +++kLlyAie+++gFels
   Q: 1003 FTDEEKRKLLRFVTSCSRPPLLGFKELYPA-FCIHNGGSDlERLPTASTCMNLLKLPEFCDEHLMRNKLLYAIESSAGFELS 1083
           ****************************88.*****99999**************************************985 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MFSFEGDFKT RPKVSLGGAS RKEEKASLLH RTQEERRKRE DERRRLKNAI IIQSYVRGYK 60
DRKQQHAIQR SEFDRCACLA QSGGGISLSD GANLTLLVRQ LLFFYRQSED SNRLIWMCQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCCAGTGC CTCCCGTTCA TGAAAAGACC TTGTGCTAAA TGAATAACTG TTGCCATGTT 60
CAGCTTTGAA GGCGATTTCA AAACAAGACC CAAGGTGTCT CTGGGGGGAG CAAGCAGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	80.28	0.00e+00	1664.00
IUUC-Apl-003731	Anas platyrhynchos	84.08	0.00e+00	1769.00
IUUC-Aca-005248	Anolis carolinensis	82.69	0.00e+00	1774.00
IUUC-Aly-005768	Arabidopsis lyrata	35.29	3.00e-106	379.00
IUUC-Ath-006576	Arabidopsis thaliana	33.29	5.00e-107	382.00
IUUC-Ago-007748	Ashbya gossypii	41.90	1.00e-78	288.00
IUUC-Acl-008158	Aspergillus clavatus	39.45	4.00e-78	286.00
IUUC-Afl-008398	Aspergillus flavus	38.51	9.00e-78	285.00
IUUC-Afu-008937	Aspergillus fumigatus	39.28	6.00e-80	292.00
IUUC-Ani-009252	Aspergillus nidulans	39.45	1.00e-82	301.00
IUUC-Ang-009773	Aspergillus niger	38.81	4.00e-78	286.00
IUUC-Aor-009940	Aspergillus oryzae	38.51	9.00e-78	285.00
IUUC-Ate-010395	Aspergillus terreus	37.95	6.00e-79	289.00
IUUC-Ame-010769	Astyanax mexicanus	65.96	0.00e+00	1088.00
IUUC-Bgr-012269	Blumeria graminis	38.48	6.00e-75	274.00
IUUC-Bta-012841	Bos taurus	80.40	0.00e+00	1697.00
IUUC-Bci-013743	Botrytis cinerea	38.54	6.00e-82	299.00
IUUC-Bol-015390	Brassica oleracea	35.38	6.00e-101	362.00
IUUC-Bra-016853	Brassica rapa	34.67	4.00e-108	385.00
IUUC-Cel-018638	Caenorhabditis elegans	31.52	2.00e-89	324.00
IUUC-Cja-019743	Callithrix jacchus	79.04	0.00e+00	1668.00
IUUC-Cfa-021031	Canis familiaris	81.56	0.00e+00	1725.00
IUUC-Cpo-022401	Cavia porcellus	81.47	0.00e+00	1719.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	43.99	5.00e-84	304.00
IUUC-Csa-024107	Chlorocebus sabaeus	80.92	0.00e+00	1730.00
IUUC-Cho-024750	Choloepus hoffmanni	75.52	0.00e+00	734.00
IUUC-Cin-025432	Ciona intestinalis	45.89	1.00e-98	352.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.38	1.00e-83	305.00
IUUC-Cne-026841	Cryptococcus neoformans	36.39	3.00e-94	340.00
IUUC-Cme-027265	Cyanidioschyzon merolae	47.34	3.00e-103	369.00
IUUC-Dre-028196	Danio rerio	83.93	0.00e+00	1736.00
IUUC-Dno-029024	Dasypus novemcinctus	80.94	0.00e+00	1732.00
IUUC-Dor-030483	Dipodomys ordii	82.08	4.00e-176	612.00
IUUC-Dse-031416	Dothistroma septosporum	32.22	1.00e-79	291.00
IUUC-Dme-031946	Drosophila melanogaster	38.09	0.00e+00	689.00
IUUC-Ete-032240	Echinops telfairi	71.88	3.00e-153	536.00
IUUC-Eca-033828	Equus caballus	80.92	0.00e+00	1686.00
IUUC-Eeu-034604	Erinaceus europaeus	80.53	2.00e-120	427.00
IUUC-Fca-035907	Felis catus	81.31	0.00e+00	1723.00
IUUC-Fal-037389	Ficedula albicollis	84.16	0.00e+00	1790.00
IUUC-Fox-037788	Fusarium oxysporum	38.04	2.00e-92	333.00
IUUC-Fso-038088	Fusarium solani	35.95	8.00e-87	315.00
IUUC-Gmo-039254	Gadus morhua	73.85	0.00e+00	1366.00
IUUC-Ggr-039941	Gaeumannomyces graminis	34.32	6.00e-83	302.00
IUUC-Gga-040310	Gallus gallus	83.79	0.00e+00	1780.00
IUUC-Gac-042054	Gasterosteus aculeatus	77.81	0.00e+00	1426.00
IUUC-Gma-042836	Glycine max	35.28	2.00e-98	353.00
IUUC-Ggo-045031	Gorilla gorilla	81.20	0.00e+00	1735.00
IUUC-Hsa-045880	Homo sapiens	81.11	0.00e+00	1734.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	68.25	6.00e-158	550.00
IUUC-Kpa-049307	Komagataella pastoris	33.27	4.00e-65	243.00
IUUC-Lch-050403	Latimeria chalumnae	82.64	0.00e+00	1672.00
IUUC-Lma-053096	Leptosphaeria maculans	38.58	2.00e-80	295.00
IUUC-Laf-054162	Loxodonta africana	77.81	0.00e+00	1465.00
IUUC-Mcc-055127	Macaca mulatta	80.92	0.00e+00	1729.00
IUUC-Meu-056187	Macropus eugenii	80.00	6.00e-103	369.00
IUUC-Mor-057021	Magnaporthe oryzae	34.84	7.00e-79	289.00
IUUC-Mpo-057570	Magnaporthe poae	36.68	2.00e-76	281.00
IUUC-Mtr-058154	Medicago truncatula	34.79	5.00e-101	362.00
IUUC-Mla-059124	Melampsora laricipopulina	47.29	9.00e-101	360.00
IUUC-Mga-059581	Meleagris gallopavo	83.43	0.00e+00	1764.00
IUUC-Mvi-060445	Microbotryum violaceum	38.79	4.00e-102	366.00
IUUC-Mmr-061360	Microcebus murinus	77.45	0.00e+00	1572.00
IUUC-Mdo-062194	Monodelphis domestica	80.09	0.00e+00	1771.00
IUUC-Mmu-064189	Mus musculus	80.37	0.00e+00	1718.00
IUUC-Mac-065275	Musa acuminata	48.56	9.00e-107	381.00
IUUC-Mpu-066439	Mustela putorius furo	78.97	0.00e+00	1658.00
IUUC-Mlu-068228	Myotis lucifugus	78.71	0.00e+00	1662.00
IUUC-Nfi-068280	Neosartorya fischeri	39.49	1.00e-80	295.00
IUUC-Ncr-068869	Neurospora crassa	36.01	6.00e-85	309.00
IUUC-Nle-069687	Nomascus leucogenys	80.43	0.00e+00	1680.00
IUUC-Opr-070592	Ochotona princeps	92.50	8.00e-110	391.00
IUUC-Ont-071836	Oreochromis niloticus	86.64	0.00e+00	1808.00
IUUC-Oan-072800	Ornithorhynchus anatinus	83.33	0.00e+00	1788.00
IUUC-Ocu-074587	Oryctolagus cuniculus	81.29	0.00e+00	1742.00
IUUC-Ola-087209	Oryzias latipes	84.79	0.00e+00	1732.00
IUUC-Olu-087699	Ostreococcus lucimarinus	42.86	1.00e-86	313.00
IUUC-Oga-088776	Otolemur garnettii	77.79	0.00e+00	1588.00
IUUC-Oar-089441	Ovis aries	79.87	0.00e+00	1680.00
IUUC-Ptr-091273	Pan troglodytes	81.11	0.00e+00	1734.00
IUUC-Pan-091981	Papio anubis	80.92	0.00e+00	1732.00
IUUC-Psi-093203	Pelodiscus sinensis	82.94	0.00e+00	1538.00
IUUC-Pma-094738	Petromyzon marinus	65.67	0.00e+00	1339.00
IUUC-Pno-095132	Phaeosphaeria nodorum	29.57	8.00e-61	228.00
IUUC-Ppa-095682	Physcomitrella patens	34.66	4.00e-110	392.00
IUUC-Pfo-097511	Poecilia formosa	85.41	0.00e+00	1792.00
IUUC-Pab-098634	Pongo abelii	78.18	0.00e+00	1652.00
IUUC-Pop-098928	Populus trichocarpa	46.04	6.00e-96	345.00
IUUC-Pca-100987	Procavia capensis	92.43	0.00e+00	750.00
IUUC-Pva-103034	Pteropus vampyrus	76.69	0.00e+00	1582.00
IUUC-Pgr-103513	Puccinia graminis	40.00	4.00e-107	382.00
IUUC-Ptt-103967	Puccinia triticina	41.43	6.00e-95	342.00
IUUC-Pte-104105	Pyrenophora teres	35.66	2.00e-81	297.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	38.15	1.00e-77	285.00
IUUC-Rno-105380	Rattus norvegicus	79.05	0.00e+00	1490.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.49	7.00e-68	252.00
IUUC-Sha-107108	Sarcophilus harrisii	77.39	0.00e+00	1614.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	43.22	2.00e-97	350.00
IUUC-Spo-108097	Schizosaccharomyces pombe	43.87	1.00e-94	341.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	29.96	4.00e-82	300.00
IUUC-Sly-111362	Solanum lycopersicum	35.29	4.00e-99	356.00
IUUC-Sar-113687	Sorex araneus	75.17	0.00e+00	837.00
IUUC-Sre-115038	Sporisorium reilianum	44.23	1.00e-97	351.00
IUUC-Ssc-115378	Sus scrofa	88.13	0.00e+00	700.00
IUUC-Tgu-116729	Taeniopygia guttata	83.44	0.00e+00	1779.00
IUUC-Tru-118068	Takifugu rubripes	83.56	0.00e+00	1748.00
IUUC-Tsy-118942	Tarsius syrichta	79.28	5.00e-179	621.00
IUUC-Tni-120732	Tetraodon nigroviridis	83.35	0.00e+00	1702.00
IUUC-Tca-121737	Theobroma cacao	35.44	2.00e-104	374.00
IUUC-Tre-121892	Trichoderma reesei	36.99	9.00e-88	318.00
IUUC-Tvi-122354	Trichoderma virens	36.51	6.00e-88	319.00
IUUC-Tme-127102	Tuber melanosporum	36.81	2.00e-95	344.00
IUUC-Tbe-127351	Tupaia belangeri	70.69	0.00e+00	1311.00
IUUC-Ttr-129061	Tursiops truncatus	77.90	0.00e+00	1624.00
IUUC-Uma-129343	Ustilago maydis	44.23	4.00e-99	356.00
IUUC-Vda-129748	Verticillium dahliae	37.72	2.00e-76	281.00
IUUC-Vvi-131234	Vitis vinifera	35.29	2.00e-100	360.00
IUUC-Xtr-132094	Xenopus tropicalis	81.53	0.00e+00	1726.00
IUUC-Xma-133923	Xiphophorus maculatus	85.50	0.00e+00	1793.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence