iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005360

UUCD1 version

UUC-AnC-01006

Ensembl Protein ID

ENSACAP00000016001.3

UniProt Accession

G1KSD9; G1KSD9_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000016248.3	ENSACAT00000016321.3	ENSACAP00000016001.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.10e-82	275.7	121	419

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC++NS+LQcL+ +p+l+++ll+ +++++++     +   ++++ +q+ + +   ++ +a++p ++++ lkk+a++f+  +q
   Q: 121  GLHNLGNTCFLNSTLQCLTYTPPLANYLLSkEHSRSCH-----QGGFCMMCIMQNHMIQAFANSGNAIKPVSFIRDLKKIARHFRFGSQ 204
           9*****************************33444443.....4578****************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++ +d++++++                  l+   + + +++ ++l++++F+g l+s++kc  c++vs +++pfld+ l++++
   Q: 205  EDAHEFLRYTIDAMQKAC------------------LNGYTKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPFLDVALEIRQ 275
           ******************..................2333455788999**************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
                  ++  +Le f+k++ l gen+y c kckkk+ a+k++++++ ++vL++ LkRf    ++ s  ki+k v +p+ L+++p++++
   Q: 276  AA-----NIVRALELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRASNVLTISLKRF----ANFSGGKITKDVGYPEFLNIRPYMSQ 355
           **.....9***************************************************....668899******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           ++ +   ++ Y L+av+vHsG s++ GHY++yvk ++g+W++++Ds V++++ + vl+   ++aYvlfY 
   Q: 356  SSGD---PVMYGLYAVLVHSGySCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKVVLN---QQAYVLFYL 419
           5544...9**************************************************...********6 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MPIVDKLKEA LKPGRKDSAD DVELGKLLAA SAKKILLQRI EFEPASKSFS YQLESLKSKY 60
ILLNPKTENP SRHKGSEEGS NRKQGIEHVL GGDGVPAPQK VLFPVERLSL KWERVYRVGA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTAAGGATC CTTTGCTGAC TGGGCAACTT GTCCTGCAAC AGAGTGATGC ACCATGCCTA 60
TAGTGGACAA ACTGAAGGAA GCCCTAAAGC CTGGGCGAAA GGACTCTGCT GATGATGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0016579--P:protein deubiquitination
GO:1903146--P:regulation of mitophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

acs:100563590

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002092	Ailuropoda melanoleuca	78.87	0.00e+00	845.00
IUUC-Bta-013047	Bos taurus	81.27	0.00e+00	820.00
IUUC-Bdi-014036	Brachypodium distachyon	46.84	1.00e-86	314.00
IUUC-Cja-019203	Callithrix jacchus	81.35	0.00e+00	831.00
IUUC-Cfa-020586	Canis familiaris	61.01	0.00e+00	844.00
IUUC-Cpo-021804	Cavia porcellus	72.91	0.00e+00	835.00
IUUC-Cre-022988	Chlamydomonas reinhardtii	48.43	1.00e-55	209.00
IUUC-Csa-023137	Chlorocebus sabaeus	65.16	0.00e+00	868.00
IUUC-Cin-025230	Ciona intestinalis	51.33	3.00e-98	351.00
IUUC-Cme-027339	Cyanidioschyzon merolae	36.62	2.00e-63	236.00
IUUC-Dre-028587	Danio rerio	74.59	0.00e+00	814.00
IUUC-Dno-029149	Dasypus novemcinctus	62.65	0.00e+00	837.00
IUUC-Dor-030836	Dipodomys ordii	65.88	0.00e+00	729.00
IUUC-Dme-032119	Drosophila melanogaster	35.16	2.00e-71	264.00
IUUC-Ete-032567	Echinops telfairi	67.04	0.00e+00	690.00
IUUC-Eca-033600	Equus caballus	60.51	0.00e+00	813.00
IUUC-Fal-036852	Ficedula albicollis	70.09	2.00e-165	576.00
IUUC-Gmo-039033	Gadus morhua	77.56	0.00e+00	811.00
IUUC-Gga-040664	Gallus gallus	79.00	0.00e+00	781.00
IUUC-Gac-042176	Gasterosteus aculeatus	71.74	0.00e+00	807.00
IUUC-Ggo-045437	Gorilla gorilla	82.61	0.00e+00	832.00
IUUC-Hsa-046863	Homo sapiens	82.61	0.00e+00	831.00
IUUC-Itr-048655	Ictidomys tridecemlineatus	64.07	0.00e+00	885.00
IUUC-Lch-050120	Latimeria chalumnae	67.67	0.00e+00	729.00
IUUC-Lpe-051574	Leersia perrieri	35.32	1.00e-83	304.00
IUUC-Loc-052796	Lepisosteus oculatus	80.32	0.00e+00	789.00
IUUC-Laf-054243	Loxodonta africana	64.44	0.00e+00	832.00
IUUC-Mcc-055762	Macaca mulatta	65.03	0.00e+00	858.00
IUUC-Meu-056697	Macropus eugenii	61.03	0.00e+00	876.00
IUUC-Mtr-058537	Medicago truncatula	47.67	3.00e-88	319.00
IUUC-Mga-059359	Meleagris gallopavo	82.22	5.00e-164	571.00
IUUC-Mmr-060966	Microcebus murinus	80.79	0.00e+00	812.00
IUUC-Mdo-062733	Monodelphis domestica	61.16	0.00e+00	873.00
IUUC-Mmu-064331	Mus musculus	78.21	0.00e+00	864.00
IUUC-Mac-065039	Musa acuminata	41.56	1.00e-88	321.00
IUUC-Mpu-065759	Mustela putorius furo	74.54	0.00e+00	808.00
IUUC-Mlu-067371	Myotis lucifugus	73.90	0.00e+00	846.00
IUUC-Nle-070087	Nomascus leucogenys	81.15	0.00e+00	806.00
IUUC-Opr-070729	Ochotona princeps	71.97	0.00e+00	755.00
IUUC-Ont-071346	Oreochromis niloticus	74.81	0.00e+00	832.00
IUUC-Oan-072931	Ornithorhynchus anatinus	83.04	0.00e+00	843.00
IUUC-Ocu-074823	Oryctolagus cuniculus	70.99	0.00e+00	770.00
IUUC-Oba-075866	Oryza barthii	42.86	1.00e-85	310.00
IUUC-Obr-076408	Oryza brachyantha	38.50	5.00e-86	312.00
IUUC-Ogl-077239	Oryza glaberrima	42.18	4.00e-86	312.00
IUUC-Ogu-078064	Oryza glumaepatula	42.86	4.00e-86	312.00
IUUC-Oin-079157	Oryza indica	42.18	4.00e-86	313.00
IUUC-Olo-080231	Oryza longistaminata	44.62	2.00e-77	284.00
IUUC-Ome-081746	Oryza meridionalis	47.06	5.00e-85	308.00
IUUC-Oni-082339	Oryza nivara	42.18	3.00e-86	313.00
IUUC-Opu-083194	Oryza punctata	42.18	4.00e-86	313.00
IUUC-Oru-085083	Oryza rufipogon	42.18	2.00e-86	313.00
IUUC-Osa-086180	Oryza sativa	42.18	3.00e-86	313.00
IUUC-Ola-087255	Oryzias latipes	69.78	0.00e+00	815.00
IUUC-Oga-088818	Otolemur garnettii	76.34	0.00e+00	818.00
IUUC-Oar-089410	Ovis aries	58.05	0.00e+00	816.00
IUUC-Ptr-090680	Pan troglodytes	82.61	0.00e+00	830.00
IUUC-Pan-092482	Papio anubis	64.90	0.00e+00	854.00
IUUC-Pfo-096807	Poecilia formosa	73.94	0.00e+00	823.00
IUUC-Pab-098724	Pongo abelii	83.37	0.00e+00	860.00
IUUC-Pop-099693	Populus trichocarpa	37.94	5.00e-87	315.00
IUUC-Pca-100117	Procavia capensis	73.90	3.00e-146	512.00
IUUC-Pva-102883	Pteropus vampyrus	64.95	0.00e+00	651.00
IUUC-Rno-105340	Rattus norvegicus	66.33	0.00e+00	831.00
IUUC-Sha-107019	Sarcophilus harrisii	61.08	0.00e+00	863.00
IUUC-Sja-107805	Schizosaccharomyces japonicus	43.20	5.00e-77	281.00
IUUC-Spo-108119	Schizosaccharomyces pombe	45.13	6.00e-87	314.00
IUUC-Sit-110536	Setaria italica	42.82	7.00e-81	295.00
IUUC-Sbi-114477	Sorghum bicolor	46.84	2.00e-87	317.00
IUUC-Sre-114924	Sporisorium reilianum	41.37	4.00e-67	249.00
IUUC-Ssc-116022	Sus scrofa	78.39	0.00e+00	805.00
IUUC-Tgu-116976	Taeniopygia guttata	72.32	4.00e-164	570.00
IUUC-Tru-118391	Takifugu rubripes	77.47	0.00e+00	818.00
IUUC-Tni-120064	Tetraodon nigroviridis	77.67	0.00e+00	810.00
IUUC-Tae-125259	Triticum aestivum	44.90	1.00e-90	327.00
IUUC-Tur-126014	Triticum urartu	44.03	3.00e-86	313.00
IUUC-Tbe-127377	Tupaia belangeri	68.31	8.00e-139	488.00
IUUC-Ttr-129259	Tursiops truncatus	76.91	0.00e+00	707.00
IUUC-Uma-129416	Ustilago maydis	43.50	2.00e-69	257.00
IUUC-Vpa-130568	Vicugna pacos	63.25	4.00e-43	169.00
IUUC-Xtr-132944	Xenopus tropicalis	77.25	0.00e+00	677.00
IUUC-Xma-133735	Xiphophorus maculatus	71.01	0.00e+00	827.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence