iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090006

Ensembl Protein ID

ENSOARP00000007525.1

UniProt Accession

W5PAR4; W5PAR4_SHEEP

Genbank Protein ID

ENSOARP00000007525

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AMGL01016474

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000007020.1	ENSOART00000007638.1	ENSOARP00000007525.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.20e-09	36.6	210	257

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++ls    +p+ + w+CpkCr 
   Q: 210  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLS---HKPKGK-WYCPKCRG 257
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MLSPANGEQI HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDEYYERFKR 60
EADGAQKRRA LHCIQRALIR SQELGDEKIQ LVSQMVELVE NRARQVDSHV ELLEAHQEAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACTCTCGC CTGGAAAATC CCCTGGGCAG AGGAGGCTGG GGGGGGGGGG GGCGCGGGGG 60
CGGGCGGGAG CCTTGCATTT TGCAGCGCCG GGCTCCGAGG GGGCGGGGGC CGGAGGAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

KEGG

oas:101116998

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	93.19	5.00e-127	446.00
IUUC-Apl-003910	Anas platyrhynchos	89.93	2.00e-122	431.00
IUUC-Aca-004874	Anolis carolinensis	88.21	2.00e-119	421.00
IUUC-Acl-008091	Aspergillus clavatus	54.93	9.00e-20	92.00
IUUC-Ate-010297	Aspergillus terreus	54.93	1.00e-19	92.00
IUUC-Ame-011262	Astyanax mexicanus	68.28	1.00e-94	339.00
IUUC-Bta-013507	Bos taurus	99.57	9.00e-102	362.00
IUUC-Cja-018925	Callithrix jacchus	89.25	7.00e-121	426.00
IUUC-Cfa-020947	Canis familiaris	92.83	2.00e-125	441.00
IUUC-Cpo-022286	Cavia porcellus	88.14	4.00e-96	344.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	29.63	1.00e-28	120.00
IUUC-Csa-023825	Chlorocebus sabaeus	88.89	2.00e-120	424.00
IUUC-Cho-024577	Choloepus hoffmanni	90.13	3.00e-97	347.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	2.00e-16	79.70
IUUC-Dno-029834	Dasypus novemcinctus	91.40	3.00e-125	441.00
IUUC-Dor-030315	Dipodomys ordii	87.98	5.00e-101	361.00
IUUC-Ete-032408	Echinops telfairi	87.23	3.00e-91	328.00
IUUC-Eca-034244	Equus caballus	91.45	1.00e-99	355.00
IUUC-Fca-035391	Felis catus	88.42	1.00e-106	379.00
IUUC-Fal-036838	Ficedula albicollis	88.89	1.00e-121	429.00
IUUC-Fox-037925	Fusarium oxysporum	64.71	9.00e-20	91.30
IUUC-Gga-040619	Gallus gallus	89.96	1.00e-122	432.00
IUUC-Gac-041996	Gasterosteus aculeatus	63.83	1.00e-89	322.00
IUUC-Ggo-045481	Gorilla gorilla	86.02	4.00e-93	335.00
IUUC-Hsa-046170	Homo sapiens	86.02	3.00e-93	335.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	91.45	1.00e-99	355.00
IUUC-Lch-050397	Latimeria chalumnae	86.02	2.00e-118	418.00
IUUC-Loc-052038	Lepisosteus oculatus	79.07	1.00e-96	345.00
IUUC-Laf-054126	Loxodonta africana	92.47	5.00e-127	446.00
IUUC-Mcc-055031	Macaca mulatta	86.38	9.00e-93	333.00
IUUC-Meu-056248	Macropus eugenii	87.39	1.00e-95	342.00
IUUC-Mga-059217	Meleagris gallopavo	87.55	7.00e-94	336.00
IUUC-Mmr-061581	Microcebus murinus	92.59	4.00e-106	377.00
IUUC-Mdo-062452	Monodelphis domestica	91.04	3.00e-124	437.00
IUUC-Mmu-063412	Mus musculus	92.11	2.00e-126	444.00
IUUC-Mpu-066479	Mustela putorius furo	91.88	3.00e-99	354.00
IUUC-Mlu-067586	Myotis lucifugus	79.00	1.00e-111	395.00
IUUC-Nle-069122	Nomascus leucogenys	89.25	7.00e-121	426.00
IUUC-Opr-070835	Ochotona princeps	83.69	3.00e-83	300.00
IUUC-Ont-071606	Oreochromis niloticus	90.00	2.00e-44	172.00
IUUC-Oan-073023	Ornithorhynchus anatinus	88.89	5.00e-120	423.00
IUUC-Ocu-073779	Oryctolagus cuniculus	85.83	1.00e-92	332.00
IUUC-Ogl-077118	Oryza glaberrima	32.96	2.00e-31	129.00
IUUC-Ola-086891	Oryzias latipes	65.00	6.00e-89	320.00
IUUC-Oga-087954	Otolemur garnettii	93.19	5.00e-128	450.00
IUUC-Ptr-090589	Pan troglodytes	88.89	2.00e-120	425.00
IUUC-Pan-091896	Papio anubis	86.38	9.00e-93	333.00
IUUC-Psi-093266	Pelodiscus sinensis	89.61	3.00e-122	430.00
IUUC-Pma-094265	Petromyzon marinus	73.97	4.00e-33	133.00
IUUC-Pab-098253	Pongo abelii	88.89	2.00e-120	424.00
IUUC-Pva-102753	Pteropus vampyrus	81.47	4.00e-87	315.00
IUUC-Rno-105964	Rattus norvegicus	86.32	4.00e-89	320.00
IUUC-Sha-107270	Sarcophilus harrisii	89.96	2.00e-122	431.00
IUUC-Tgu-116822	Taeniopygia guttata	89.96	9.00e-123	432.00
IUUC-Tni-119980	Tetraodon nigroviridis	57.52	9.00e-79	286.00
IUUC-Tre-121950	Trichoderma reesei	66.07	7.00e-20	92.80
IUUC-Tvi-122341	Trichoderma virens	64.29	1.00e-16	78.60
IUUC-Ttr-128672	Tursiops truncatus	91.88	7.00e-102	363.00
IUUC-Uma-129581	Ustilago maydis	57.14	2.00e-21	97.40
IUUC-Xtr-132200	Xenopus tropicalis	83.87	5.00e-112	396.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence