iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118168

Ensembl Protein ID

ENSTRUP00000035350.1

UniProt Accession

H2UEI1; H2UEI1_TAKRU

Protein Name

Inhibitor of growth protein

Gene Name

ing2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000013831.1	ENSTRUT00000035478.1	ENSTRUP00000035350.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.00e-08	36.4	214	260

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C++ + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 214  TYC-LCEQVSYGE--MIGCDNdqCPiEWFHFSCVGLT---YKPKGK-WYCPKCR 260
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MLGHQYPNAD KSQQLVSYVE DYLECVESLP LDIQRNVSLL REIDAKYQDV LKEVDEVFEK 60
YKGEQDVSQK KRLQTQLQRA LIISQELGDE KIHVVTQMTE LIENCSRQMD SHSLYLQGPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTAGGTC ACCAATATCC AAATGCCGAC AAGTCACAAC AACTGGTCAG CTATGTGGAG 60
GATTATCTGG AATGTGTGGA GTCCCTGCCT TTGGACATAC AAAGAAACGT TTCTCTGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

KEGG

tru:101075966

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	60.95	3.00e-71	261.00
IUUC-Aca-004990	Anolis carolinensis	59.33	1.00e-75	276.00
IUUC-Ame-011426	Astyanax mexicanus	66.90	3.00e-82	298.00
IUUC-Bta-012721	Bos taurus	60.22	1.00e-70	259.00
IUUC-Cja-018960	Callithrix jacchus	60.95	3.00e-64	238.00
IUUC-Cfa-020869	Canis familiaris	60.95	5.00e-71	260.00
IUUC-Cpo-021414	Cavia porcellus	60.58	3.00e-70	258.00
IUUC-Csa-023304	Chlorocebus sabaeus	61.31	7.00e-65	240.00
IUUC-Cho-024577	Choloepus hoffmanni	53.39	5.00e-54	203.00
IUUC-Cne-027005	Cryptococcus neoformans	47.76	6.00e-16	78.20
IUUC-Dre-028562	Danio rerio	71.48	2.00e-90	325.00
IUUC-Dno-029945	Dasypus novemcinctus	60.07	4.00e-70	257.00
IUUC-Dor-030141	Dipodomys ordii	58.51	6.00e-69	253.00
IUUC-Ete-032709	Echinops telfairi	60.58	2.00e-79	288.00
IUUC-Eca-033432	Equus caballus	60.95	7.00e-71	260.00
IUUC-Eeu-035285	Erinaceus europaeus	60.28	7.00e-56	209.00
IUUC-Fca-036467	Felis catus	60.95	4.00e-71	261.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.90
IUUC-Gmo-038748	Gadus morhua	71.83	7.00e-99	353.00
IUUC-Gac-041403	Gasterosteus aculeatus	82.21	8.00e-118	416.00
IUUC-Ggo-045481	Gorilla gorilla	52.44	2.00e-53	202.00
IUUC-Hsa-045837	Homo sapiens	61.31	7.00e-65	240.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	60.95	4.00e-71	261.00
IUUC-Lch-049965	Latimeria chalumnae	61.70	2.00e-83	301.00
IUUC-Mcc-055031	Macaca mulatta	52.68	2.00e-53	202.00
IUUC-Meu-056470	Macropus eugenii	63.64	2.00e-78	285.00
IUUC-Mga-059570	Meleagris gallopavo	58.97	3.00e-62	231.00
IUUC-Mmr-061385	Microcebus murinus	60.95	2.00e-64	238.00
IUUC-Mdo-062144	Monodelphis domestica	63.64	3.00e-78	285.00
IUUC-Mmu-063215	Mus musculus	59.12	7.00e-69	253.00
IUUC-Mpu-065749	Mustela putorius furo	60.64	7.00e-62	229.00
IUUC-Nle-069122	Nomascus leucogenys	55.47	1.00e-71	262.00
IUUC-Opr-070835	Ochotona princeps	49.32	3.00e-49	188.00
IUUC-Ont-071524	Oreochromis niloticus	86.48	5.00e-117	413.00
IUUC-Oan-073023	Ornithorhynchus anatinus	53.43	5.00e-71	261.00
IUUC-Ocu-074870	Oryctolagus cuniculus	60.95	3.00e-71	261.00
IUUC-Ola-087400	Oryzias latipes	80.69	2.00e-80	291.00
IUUC-Oga-088336	Otolemur garnettii	60.95	1.00e-64	239.00
IUUC-Oar-090136	Ovis aries	56.94	6.00e-69	253.00
IUUC-Ptr-090589	Pan troglodytes	55.09	3.00e-71	261.00
IUUC-Pan-092819	Papio anubis	61.31	7.00e-65	240.00
IUUC-Psi-093266	Pelodiscus sinensis	55.68	2.00e-72	265.00
IUUC-Pfo-096633	Poecilia formosa	84.70	1.00e-107	382.00
IUUC-Pab-098346	Pongo abelii	61.31	9.00e-65	239.00
IUUC-Pca-100278	Procavia capensis	61.36	1.00e-77	282.00
IUUC-Pva-103190	Pteropus vampyrus	60.95	2.00e-71	261.00
IUUC-Rno-104940	Rattus norvegicus	59.49	6.00e-69	253.00
IUUC-Sha-107533	Sarcophilus harrisii	63.26	3.00e-78	284.00
IUUC-Sar-113630	Sorex araneus	59.35	2.00e-54	204.00
IUUC-Ssc-115734	Sus scrofa	60.95	3.00e-71	261.00
IUUC-Tsy-119494	Tarsius syrichta	59.00	9.00e-50	189.00
IUUC-Tni-119663	Tetraodon nigroviridis	93.86	2.00e-125	441.00
IUUC-Ttr-128442	Tursiops truncatus	59.81	3.00e-55	207.00
IUUC-Vpa-130063	Vicugna pacos	61.31	2.00e-71	261.00
IUUC-Xtr-132200	Xenopus tropicalis	53.58	2.00e-68	252.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence