iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073583

UUCD1 version

UUC-OrA-00845

Ensembl Protein ID

ENSOANP00000014137.2

UniProt Accession

F7EVK8; F7EVK8_ORNAN

Protein Name

Uncharacterized protein

Gene Name

USP46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000008879.2	ENSOANT00000014140.2	ENSOANP00000014137.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.10e-85	286.6	28	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 17   QcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldql 103
            +L++++++re++l  +k +      +++k++ll +l++lf+++   k+k +++ p+++++ l+ke+  f++y+qqDa+Efl++ll+++
   Q: 28   NALYFCRPFRENVLA-YKAQ------QKKKENLLACLADLFHSIAtqKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTI 109
           68*************.3333......567899************976777779************************************ PP
   S: 104  eeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLe 192
            + l+   +++k+e+ + + ++ + ++  +++k+++++++++Fqg+l+++++cl+c++vss++e+fldls++v++++     s+++cL+
   Q: 110  ADILQ---EEKKQEKPNGKLRNGHLSEAGENDKSEPTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNT-----SITHCLR 190
           ****3...3444444444445555556788999999*****************************************.....9****** PP
   S: 193  sftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLi 281
           +f+++e+l++e+kyyce+c++kqea+k++++kklP +L lhLkRf++ e+ ++ +k++ +v fpleL l  f+ts++  ++ ++ Y+L+
   Q: 191  DFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRL--FNTSSDA-VNLDRMYDLV 276
           ****************************************************************66555..7777554.4459****** PP
   S: 282  avvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 277  AVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 341
           *********************.888*******************999*****************97 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MGTNASALEK DIGPEQFPIN EHYFGLVNAL YFCRPFRENV LAYKAQQKKK ENLLACLADL 60
FHSIATQKKK VGVIPPKKFI SRLRKENDLF DNYMQQDAHE FLNYLLNTIA DILQEEKKQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCTCTTTC CACCGAACCA TGCTGCTTCT CAATTTATTT TGATGGTAAG TATAGTACAC 60
AGTAAGTGCT TAACAAATAC CATTATTATT ATTATTTTTA TTATCCACCC CAATGTTTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008343--P:adult feeding behavior
GO:0001662--P:behavioral fear response
GO:0048149--P:behavioral response to ethanol
GO:0016579--P:protein deubiquitination
GO:0032228--P:regulation of synaptic transmission, GABAergic
GO:0060013--P:righting reflex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002353	Ailuropoda melanoleuca	93.52	0.00e+00	648.00
IUUC-Apl-003380	Anas platyrhynchos	92.96	0.00e+00	645.00
IUUC-Aca-005031	Anolis carolinensis	92.11	0.00e+00	681.00
IUUC-Ago-007871	Ashbya gossypii	38.91	4.00e-50	192.00
IUUC-Ame-010862	Astyanax mexicanus	89.94	0.00e+00	661.00
IUUC-Bta-013023	Bos taurus	93.50	0.00e+00	647.00
IUUC-Cja-018956	Callithrix jacchus	93.50	0.00e+00	645.00
IUUC-Cfa-021064	Canis familiaris	92.94	0.00e+00	637.00
IUUC-Cpo-022443	Cavia porcellus	93.22	0.00e+00	644.00
IUUC-Csa-023841	Chlorocebus sabaeus	93.52	0.00e+00	649.00
IUUC-Cne-026900	Cryptococcus neoformans	42.65	2.00e-60	226.00
IUUC-Dno-029209	Dasypus novemcinctus	93.50	0.00e+00	644.00
IUUC-Dme-032038	Drosophila melanogaster	81.86	5.00e-102	363.00
IUUC-Eca-033721	Equus caballus	93.50	0.00e+00	646.00
IUUC-Eeu-034916	Erinaceus europaeus	91.16	8.00e-147	512.00
IUUC-Fca-036299	Felis catus	93.50	0.00e+00	645.00
IUUC-Gmo-038611	Gadus morhua	90.40	0.00e+00	656.00
IUUC-Gga-041157	Gallus gallus	93.24	0.00e+00	647.00
IUUC-Ggo-044659	Gorilla gorilla	93.50	0.00e+00	645.00
IUUC-Hsa-046156	Homo sapiens	93.52	0.00e+00	649.00
IUUC-Itr-048157	Ictidomys tridecemlineatus	93.52	0.00e+00	649.00
IUUC-Kpa-049250	Komagataella pastoris	43.79	4.00e-69	254.00
IUUC-Lch-049969	Latimeria chalumnae	91.55	0.00e+00	626.00
IUUC-Loc-052479	Lepisosteus oculatus	87.39	0.00e+00	640.00
IUUC-Lma-053300	Leptosphaeria maculans	45.68	6.00e-78	284.00
IUUC-Laf-054085	Loxodonta africana	93.52	0.00e+00	649.00
IUUC-Mcc-055566	Macaca mulatta	93.50	0.00e+00	646.00
IUUC-Mpo-057424	Magnaporthe poae	42.72	7.00e-75	274.00
IUUC-Mla-059142	Melampsora laricipopulina	54.27	5.00e-95	342.00
IUUC-Mga-059575	Meleagris gallopavo	93.22	0.00e+00	643.00
IUUC-Mvi-060357	Microbotryum violaceum	53.96	4.00e-78	285.00
IUUC-Mdo-062579	Monodelphis domestica	93.52	0.00e+00	647.00
IUUC-Mmu-063611	Mus musculus	93.52	0.00e+00	649.00
IUUC-Mpu-066038	Mustela putorius furo	93.50	0.00e+00	645.00
IUUC-Mlu-068183	Myotis lucifugus	93.22	0.00e+00	645.00
IUUC-Nle-069330	Nomascus leucogenys	93.52	0.00e+00	649.00
IUUC-Opr-070980	Ochotona princeps	93.50	0.00e+00	645.00
IUUC-Ont-072134	Oreochromis niloticus	91.06	0.00e+00	671.00
IUUC-Ocu-074923	Oryctolagus cuniculus	93.50	0.00e+00	646.00
IUUC-Ola-086546	Oryzias latipes	91.04	0.00e+00	663.00
IUUC-Oga-088073	Otolemur garnettii	93.50	0.00e+00	646.00
IUUC-Oar-089248	Ovis aries	93.50	0.00e+00	645.00
IUUC-Ptr-090814	Pan troglodytes	93.52	0.00e+00	649.00
IUUC-Pan-091753	Papio anubis	93.52	0.00e+00	649.00
IUUC-Psi-094012	Pelodiscus sinensis	93.79	0.00e+00	646.00
IUUC-Pfo-097369	Poecilia formosa	91.34	0.00e+00	671.00
IUUC-Pab-098594	Pongo abelii	93.52	0.00e+00	647.00
IUUC-Pca-100913	Procavia capensis	77.46	1.00e-144	504.00
IUUC-Pva-102892	Pteropus vampyrus	93.50	0.00e+00	645.00
IUUC-Pte-104356	Pyrenophora teres	45.93	7.00e-77	281.00
IUUC-Rno-104909	Rattus norvegicus	93.52	0.00e+00	648.00
IUUC-Sha-107400	Sarcophilus harrisii	93.50	0.00e+00	644.00
IUUC-Sre-115197	Sporisorium reilianum	49.47	2.00e-81	297.00
IUUC-Ssc-115550	Sus scrofa	93.50	0.00e+00	645.00
IUUC-Tgu-116800	Taeniopygia guttata	93.24	0.00e+00	647.00
IUUC-Tru-118212	Takifugu rubripes	90.78	0.00e+00	669.00
IUUC-Tni-120071	Tetraodon nigroviridis	90.78	0.00e+00	668.00
IUUC-Uma-129409	Ustilago maydis	49.48	2.00e-81	297.00
IUUC-Vpa-130590	Vicugna pacos	88.73	6.00e-173	599.00
IUUC-Xma-133111	Xiphophorus maculatus	90.78	0.00e+00	668.00
IUUC-Yli-134632	Yarrowia lipolytica	45.55	5.00e-79	288.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence