iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000007849.2	ENSPPYT00000033736.1	ENSPPYP00000024474.1
ENSPPYG00000007849.2	ENSPPYT00000009200.1	ENSPPYP00000008838.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.40e-09	38.4	254	296

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCl++++dg  ++vlpC H++h  C+  w     +++++ +CP+C+
   Q: 254  CAICLDEYEDGdkLRVLPCAHAYHSRCVDPW-----LTQTRKTCPICK 296
           ********66666******************.....8**********7 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MHPTAFPLPV VVAAVLWGAA PTRGLIRATS DHNASMDFAD LPALFGATLS QEGLQGFLVE 60
AHPDNACSPI APPPPAPVNG SVFIALLRRF DCNFDLKVLN AQKAGYGAAV VHNVNSNELL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGGAGGGG CAGGGAGGGC GCAGAACTCC GCTTCTGCTC CTTGCTACCA GGACGCGCGG 60
CCTCCTCAGC CTCTTTCCTC CCGCTGCCAT GCACCCTACA GCCTTCCCGC TTCCTGTGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045786--P:negative regulation of cell cycle
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001413	Ailuropoda melanoleuca	83.71	1.00e-133	469.00
IUUC-Acl-008256	Aspergillus clavatus	60.42	7.00e-14	71.20
IUUC-Afl-008548	Aspergillus flavus	62.22	1.00e-13	70.50
IUUC-Afu-008977	Aspergillus fumigatus	62.22	3.00e-13	69.70
IUUC-Ang-009734	Aspergillus niger	56.86	2.00e-14	73.60
IUUC-Aor-010134	Aspergillus oryzae	62.22	1.00e-13	70.90
IUUC-Ate-010329	Aspergillus terreus	62.22	2.00e-13	70.10
IUUC-Bgr-012220	Blumeria graminis	55.56	2.00e-12	67.00
IUUC-Bta-012651	Bos taurus	86.42	1.00e-123	436.00
IUUC-Cja-018953	Callithrix jacchus	91.02	4.00e-147	513.00
IUUC-Cfa-020540	Canis familiaris	66.55	3.00e-91	328.00
IUUC-Cpo-022372	Cavia porcellus	85.67	1.00e-164	572.00
IUUC-Cre-022631	Chlamydomonas reinhardtii	29.79	4.00e-23	102.00
IUUC-Csa-023070	Chlorocebus sabaeus	92.51	2.00e-159	555.00
IUUC-Cne-026954	Cryptococcus neoformans	57.45	5.00e-13	68.90
IUUC-Dre-028786	Danio rerio	53.14	2.00e-77	283.00
IUUC-Dno-028877	Dasypus novemcinctus	87.92	7.00e-166	576.00
IUUC-Dor-030128	Dipodomys ordii	77.81	2.00e-147	514.00
IUUC-Ete-033067	Echinops telfairi	97.51	6.00e-105	373.00
IUUC-Eca-033699	Equus caballus	87.36	1.00e-155	541.00
IUUC-Eeu-034819	Erinaceus europaeus	86.83	2.00e-147	514.00
IUUC-Fca-036168	Felis catus	88.00	3.00e-145	507.00
IUUC-Fox-037990	Fusarium oxysporum	60.00	3.00e-13	69.70
IUUC-Fso-038278	Fusarium solani	60.00	6.00e-13	68.60
IUUC-Gac-041339	Gasterosteus aculeatus	48.44	2.00e-75	275.00
IUUC-Gma-043776	Glycine max	31.99	1.00e-29	124.00
IUUC-Ggo-045113	Gorilla gorilla	92.66	4.00e-162	563.00
IUUC-Hsa-046476	Homo sapiens	88.98	7.00e-161	559.00
IUUC-Itr-047953	Ictidomys tridecemlineatus	86.52	3.00e-165	574.00
IUUC-Lma-053199	Leptosphaeria maculans	48.33	2.00e-14	73.20
IUUC-Laf-053687	Loxodonta africana	90.39	4.00e-152	530.00
IUUC-Mcc-055879	Macaca mulatta	89.22	2.00e-160	558.00
IUUC-Meu-056408	Macropus eugenii	72.33	1.00e-111	395.00
IUUC-Mor-057236	Magnaporthe oryzae	39.77	1.00e-13	70.90
IUUC-Mmr-060656	Microcebus murinus	89.89	5.00e-169	586.00
IUUC-Mdo-062795	Monodelphis domestica	82.39	7.00e-134	470.00
IUUC-Mmu-063722	Mus musculus	85.11	1.00e-160	559.00
IUUC-Mpu-066094	Mustela putorius furo	85.41	3.00e-142	497.00
IUUC-Mlu-067350	Myotis lucifugus	86.52	3.00e-151	527.00
IUUC-Nfi-068514	Neosartorya fischeri	62.22	2.00e-13	70.10
IUUC-Nle-069971	Nomascus leucogenys	93.22	3.00e-160	557.00
IUUC-Opr-070716	Ochotona princeps	95.07	1.00e-109	389.00
IUUC-Oan-072710	Ornithorhynchus anatinus	72.32	2.00e-68	251.00
IUUC-Ocu-074157	Oryctolagus cuniculus	91.32	8.00e-158	549.00
IUUC-Oga-089169	Otolemur garnettii	90.73	2.00e-171	594.00
IUUC-Oar-089216	Ovis aries	89.70	4.00e-153	533.00
IUUC-Ptr-091493	Pan troglodytes	92.37	4.00e-162	563.00
IUUC-Pan-092215	Papio anubis	92.63	3.00e-159	553.00
IUUC-Psi-093038	Pelodiscus sinensis	57.49	1.00e-101	362.00
IUUC-Pno-094907	Phaeosphaeria nodorum	62.22	5.00e-14	72.00
IUUC-Pca-100609	Procavia capensis	87.92	7.00e-153	533.00
IUUC-Pva-102834	Pteropus vampyrus	86.24	2.00e-163	568.00
IUUC-Pte-104147	Pyrenophora teres	60.00	2.00e-13	70.50
IUUC-Pyt-104748	Pyrenophora triticirepentis	62.22	1.00e-13	70.90
IUUC-Rno-106080	Rattus norvegicus	88.20	4.00e-162	563.00
IUUC-Sha-106787	Sarcophilus harrisii	80.40	1.00e-129	455.00
IUUC-Stu-112408	Solanum tuberosum	32.09	3.00e-28	119.00
IUUC-Sar-113580	Sorex araneus	74.72	4.00e-121	427.00
IUUC-Ssc-115900	Sus scrofa	87.64	2.00e-169	587.00
IUUC-Tru-118584	Takifugu rubripes	49.18	7.00e-82	296.00
IUUC-Tsy-119134	Tarsius syrichta	83.84	3.00e-92	330.00
IUUC-Tni-120357	Tetraodon nigroviridis	54.44	6.00e-83	300.00
IUUC-Tre-121885	Trichoderma reesei	57.78	1.00e-12	67.40
IUUC-Tvi-122633	Trichoderma virens	57.78	1.00e-12	67.40
IUUC-Tae-123096	Triticum aestivum	33.93	4.00e-30	125.00
IUUC-Tbe-127812	Tupaia belangeri	85.71	4.00e-126	443.00
IUUC-Ttr-128409	Tursiops truncatus	86.38	5.00e-128	449.00
IUUC-Vvi-131036	Vitis vinifera	31.80	7.00e-31	127.00
IUUC-Xma-133568	Xiphophorus maculatus	50.51	3.00e-71	261.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence