iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
HINT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.40e-06	28.3	196	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +Cl  + + p ++pCgH+f+++Cl  +    +s  +  +CPlCr
   Q: 196  CTVCLKLLYE-PATTPCGHTFCRSCL--F----QSMDRGNKCPLCR 234
           99****9988.**************9..3....55678888****8 PP

Organism

Arabidopsis thaliana

Protein Sequence
(Fasta)

MSNEDSLPPF TLFGLDDVEN YGLVTEADNS LPLDIHNQVF QLVEKGNQSF KESRFEEAIS 60
SYSKANSIKP LDPIVLGNRS AAYIRFGQYL KQRSASISEY KPLNGFDMSM LGELALKDAD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAACAAGTT AAGTTAAGTT AAGTTAAGTT GTTAAGTTGT TATTATTAAA AGTAGAATTA 60
TTTTTTTTTA ATTTAGCCAA AAACTAAACT GAAAAGTACA TATGAATATT TGCTTACTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR011990--TPR-like_helical_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg

SMART

SM00464--LON
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001989	Ailuropoda melanoleuca	33.55	3.00e-43	169.00
IUUC-Atr-002972	Amborella trichopoda	57.47	1.00e-144	505.00
IUUC-Apl-003355	Anas platyrhynchos	35.79	1.00e-39	156.00
IUUC-Aca-004822	Anolis carolinensis	33.55	2.00e-39	157.00
IUUC-Aly-005476	Arabidopsis lyrata	94.70	0.00e+00	928.00
IUUC-Acl-008224	Aspergillus clavatus	32.00	9.00e-31	127.00
IUUC-Afu-008802	Aspergillus fumigatus	28.67	1.00e-28	120.00
IUUC-Ani-009473	Aspergillus nidulans	32.09	1.00e-32	134.00
IUUC-Ang-009643	Aspergillus niger	33.66	7.00e-27	114.00
IUUC-Ate-010489	Aspergillus terreus	30.38	3.00e-28	119.00
IUUC-Ame-010916	Astyanax mexicanus	38.12	1.00e-39	157.00
IUUC-Bgr-011969	Blumeria graminis	35.21	7.00e-09	54.30
IUUC-Bta-012903	Bos taurus	33.87	2.00e-42	166.00
IUUC-Bdi-014333	Brachypodium distachyon	56.46	7.00e-127	446.00
IUUC-Bol-016150	Brassica oleracea	92.65	0.00e+00	866.00
IUUC-Bra-016716	Brassica rapa	90.00	0.00e+00	879.00
IUUC-Cel-018356	Caenorhabditis elegans	38.37	9.00e-12	62.00
IUUC-Cja-019312	Callithrix jacchus	34.19	3.00e-43	169.00
IUUC-Cfa-020159	Canis familiaris	33.87	1.00e-42	167.00
IUUC-Cpo-022528	Cavia porcellus	33.87	5.00e-40	158.00
IUUC-Cre-022730	Chlamydomonas reinhardtii	29.26	1.00e-12	66.20
IUUC-Csa-023361	Chlorocebus sabaeus	34.19	5.00e-41	162.00
IUUC-Cho-024549	Choloepus hoffmanni	36.47	5.00e-38	151.00
IUUC-Cin-025668	Ciona intestinalis	28.62	1.00e-29	124.00
IUUC-Csv-026364	Ciona savignyi	28.12	9.00e-32	130.00
IUUC-Cgl-026514	Colletotrichum gloeosporioides	27.95	1.00e-28	120.00
IUUC-Cne-026875	Cryptococcus neoformans	37.04	3.00e-12	66.20
IUUC-Cme-027153	Cyanidioschyzon merolae	46.75	4.00e-20	92.00
IUUC-Dre-028195	Danio rerio	32.67	2.00e-40	159.00
IUUC-Dno-029284	Dasypus novemcinctus	33.23	1.00e-41	163.00
IUUC-Dor-031132	Dipodomys ordii	33.91	2.00e-35	144.00
IUUC-Dse-031331	Dothistroma septosporum	28.25	4.00e-25	108.00
IUUC-Dme-031919	Drosophila melanogaster	27.09	2.00e-26	114.00
IUUC-Ete-032455	Echinops telfairi	34.19	7.00e-43	167.00
IUUC-Eca-033248	Equus caballus	33.55	5.00e-40	157.00
IUUC-Eeu-034441	Erinaceus europaeus	33.55	1.00e-42	166.00
IUUC-Fca-035551	Felis catus	33.55	1.00e-42	167.00
IUUC-Fal-036731	Ficedula albicollis	31.79	1.00e-41	164.00
IUUC-Fox-037926	Fusarium oxysporum	30.67	7.00e-08	50.10
IUUC-Fso-038334	Fusarium solani	36.50	7.00e-29	121.00
IUUC-Gmo-038475	Gadus morhua	32.33	7.00e-40	156.00
IUUC-Gga-040888	Gallus gallus	32.12	4.00e-42	164.00
IUUC-Gac-041944	Gasterosteus aculeatus	32.18	4.00e-38	150.00
IUUC-Gma-042919	Glycine max	62.99	7.00e-164	569.00
IUUC-Ggo-044985	Gorilla gorilla	33.87	9.00e-43	167.00
IUUC-Hsa-046592	Homo sapiens	33.87	1.00e-42	167.00
IUUC-Hvu-047145	Hordeum vulgare	55.09	5.00e-93	333.00
IUUC-Itr-048573	Ictidomys tridecemlineatus	34.19	4.00e-43	169.00
IUUC-Kpa-049137	Komagataella pastoris	24.10	4.00e-10	58.90
IUUC-Lch-049788	Latimeria chalumnae	31.67	5.00e-36	145.00
IUUC-Loc-052858	Lepisosteus oculatus	33.55	2.00e-39	156.00
IUUC-Lma-053145	Leptosphaeria maculans	27.83	2.00e-29	123.00
IUUC-Laf-053431	Loxodonta africana	34.52	2.00e-43	169.00
IUUC-Mcc-055751	Macaca mulatta	34.19	5.00e-41	162.00
IUUC-Meu-055901	Macropus eugenii	25.08	6.00e-22	98.60
IUUC-Mor-056963	Magnaporthe oryzae	31.51	2.00e-25	110.00
IUUC-Mtr-058075	Medicago truncatula	65.10	3.00e-171	593.00
IUUC-Mla-058946	Melampsora laricipopulina	30.82	7.00e-34	137.00
IUUC-Mga-059472	Meleagris gallopavo	37.12	2.00e-40	158.00
IUUC-Mvi-060228	Microbotryum violaceum	32.75	4.00e-35	142.00
IUUC-Mmr-061283	Microcebus murinus	34.52	1.00e-43	170.00
IUUC-Mdo-062261	Monodelphis domestica	32.76	2.00e-39	156.00
IUUC-Mmu-063169	Mus musculus	34.19	1.00e-42	167.00
IUUC-Mac-065566	Musa acuminata	64.92	1.00e-123	436.00
IUUC-Mpu-066537	Mustela putorius furo	33.87	2.00e-40	160.00
IUUC-Mlu-067497	Myotis lucifugus	33.55	4.00e-43	168.00
IUUC-Nfi-068337	Neosartorya fischeri	29.13	6.00e-30	124.00
IUUC-Nle-068971	Nomascus leucogenys	33.87	6.00e-43	167.00
IUUC-Opr-070791	Ochotona princeps	33.55	2.00e-42	166.00
IUUC-Ont-072148	Oreochromis niloticus	33.11	3.00e-42	166.00
IUUC-Oan-072747	Ornithorhynchus anatinus	33.12	5.00e-44	171.00
IUUC-Ocu-074928	Oryctolagus cuniculus	34.19	3.00e-43	168.00
IUUC-Oba-075239	Oryza barthii	55.40	7.00e-141	493.00
IUUC-Obr-076158	Oryza brachyantha	54.94	6.00e-139	486.00
IUUC-Ogu-078154	Oryza glumaepatula	59.87	3.00e-108	385.00
IUUC-Oin-079067	Oryza indica	57.73	7.00e-115	407.00
IUUC-Olo-080663	Oryza longistaminata	56.94	1.00e-140	492.00
IUUC-Oni-082119	Oryza nivara	55.40	4.00e-144	503.00
IUUC-Opu-083266	Oryza punctata	52.15	5.00e-122	430.00
IUUC-Oru-085190	Oryza rufipogon	56.94	2.00e-140	491.00
IUUC-Ola-087198	Oryzias latipes	33.22	9.00e-43	166.00
IUUC-Olu-087810	Ostreococcus lucimarinus	20.58	2.00e-09	57.80
IUUC-Oga-088719	Otolemur garnettii	34.52	2.00e-43	170.00
IUUC-Oar-089577	Ovis aries	33.87	7.00e-43	167.00
IUUC-Ptr-090711	Pan troglodytes	33.87	1.00e-42	167.00
IUUC-Pan-092587	Papio anubis	34.19	7.00e-41	161.00
IUUC-Psi-093423	Pelodiscus sinensis	31.97	1.00e-39	157.00
IUUC-Pma-094231	Petromyzon marinus	38.43	1.00e-39	155.00
IUUC-Pno-094889	Phaeosphaeria nodorum	29.87	2.00e-32	132.00
IUUC-Pfo-096795	Poecilia formosa	34.26	8.00e-44	171.00
IUUC-Pab-097800	Pongo abelii	33.87	1.00e-42	167.00
IUUC-Pop-100044	Populus trichocarpa	67.24	0.00e+00	654.00
IUUC-Pca-100905	Procavia capensis	36.73	1.00e-31	130.00
IUUC-Ppe-101621	Prunus persica	62.56	4.00e-157	547.00
IUUC-Pva-102242	Pteropus vampyrus	34.50	1.00e-28	120.00
IUUC-Pgr-103289	Puccinia graminis	26.00	4.00e-22	99.00
IUUC-Ptt-103898	Puccinia triticina	26.61	2.00e-21	96.70
IUUC-Pte-104214	Pyrenophora teres	27.44	2.00e-26	113.00
IUUC-Pyt-104565	Pyrenophora triticirepentis	27.52	5.00e-27	115.00
IUUC-Rno-105718	Rattus norvegicus	33.87	2.00e-42	167.00
IUUC-Sha-107565	Sarcophilus harrisii	36.76	2.00e-38	154.00
IUUC-Sja-107742	Schizosaccharomyces japonicus	31.23	2.00e-25	109.00
IUUC-Spo-108344	Schizosaccharomyces pombe	27.98	5.00e-18	85.10
IUUC-Sit-110495	Setaria italica	57.63	3.00e-140	491.00
IUUC-Sly-111396	Solanum lycopersicum	62.06	2.00e-161	561.00
IUUC-Sar-113220	Sorex araneus	32.89	1.00e-38	152.00
IUUC-Sbi-114779	Sorghum bicolor	53.66	1.00e-104	372.00
IUUC-Sre-114977	Sporisorium reilianum	39.68	2.00e-16	80.90
IUUC-Ssc-115733	Sus scrofa	33.65	2.00e-42	166.00
IUUC-Tgu-117431	Taeniopygia guttata	32.12	8.00e-41	160.00
IUUC-Tru-118274	Takifugu rubripes	33.23	2.00e-41	163.00
IUUC-Tsy-119043	Tarsius syrichta	33.65	1.00e-42	167.00
IUUC-Tni-120476	Tetraodon nigroviridis	31.83	2.00e-40	158.00
IUUC-Tca-121632	Theobroma cacao	64.47	0.00e+00	641.00
IUUC-Tre-121992	Trichoderma reesei	31.58	5.00e-09	55.10
IUUC-Tvi-122557	Trichoderma virens	28.75	1.00e-04	40.40
IUUC-Tae-125900	Triticum aestivum	54.94	1.00e-144	505.00
IUUC-Tur-126297	Triticum urartu	56.87	4.00e-107	381.00
IUUC-Tme-127112	Tuber melanosporum	29.57	5.00e-27	115.00
IUUC-Tbe-127284	Tupaia belangeri	33.55	6.00e-39	154.00
IUUC-Ttr-128875	Tursiops truncatus	33.33	5.00e-31	129.00
IUUC-Uma-129541	Ustilago maydis	44.23	7.00e-16	79.30
IUUC-Vda-129721	Verticillium dahliae	25.00	2.00e-19	89.70
IUUC-Vpa-130408	Vicugna pacos	32.90	3.00e-37	149.00
IUUC-Vvi-130910	Vitis vinifera	60.04	1.00e-169	588.00
IUUC-Xtr-132417	Xenopus tropicalis	32.47	6.00e-39	154.00
IUUC-Xma-133579	Xiphophorus maculatus	34.26	2.00e-42	166.00
IUUC-Yli-134610	Yarrowia lipolytica	30.10	2.00e-09	56.20
IUUC-Zma-135914	Zea mays	50.47	1.00e-94	339.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence