iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073390

UUCD1 version

UUC-OrA-00028

Ensembl Protein ID

ENSOANP00000003865.1

UniProt Accession

F6ZR69; F6ZR69_ORNAN

Protein Name

Uncharacterized protein

Gene Name

ITSN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000002436.3	ENSOANT00000003866.1	ENSOANP00000003865.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.10e-62	206.0	1159	1210

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+ +ydy aqnddeL + kG ++ v+  +++d +W+kg  e++g+ GlfP+n+v+
   Q: 1159 QVIGMYDYAAQNDDELAFGKGQIINVL--NKEDPDWWKG--EANGQVGLFPSNYVK 1210
           46779**********************..8889******..9*************8 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MAQFPAPFGG TLDIWAITVE ERAKHDQQFH SLKPTSGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDQMEFSI AMKLIKLKLQ GYQLPSALPP IMKQQPIAIS GAPAFGIGGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCAGT TTCCGGCTCC TTTCGGGGGT AAGTTGTTCA GAGTTCTCTG CTTGAATTTT 60
TTTCTTGTTC TTCAATCTTC AAGGTTTGCC ATTTTTATTT TTGAAATAAA AATACTACTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	41.67	2.00e-14	74.70
IUUC-Aml-001218	Ailuropoda melanoleuca	84.48	0.00e+00	2179.00
IUUC-Atr-002491	Amborella trichopoda	33.33	4.00e-12	67.00
IUUC-Apl-003335	Anas platyrhynchos	87.08	0.00e+00	2174.00
IUUC-Aca-005130	Anolis carolinensis	85.02	0.00e+00	2146.00
IUUC-Ath-007330	Arabidopsis thaliana	41.46	8.00e-12	65.90
IUUC-Ago-007935	Ashbya gossypii	33.33	2.00e-12	67.00
IUUC-Afu-008916	Aspergillus fumigatus	30.28	7.00e-26	112.00
IUUC-Ani-009469	Aspergillus nidulans	31.07	4.00e-26	113.00
IUUC-Ang-009722	Aspergillus niger	30.82	1.00e-15	78.20
IUUC-Aor-010021	Aspergillus oryzae	29.38	8.00e-18	85.10
IUUC-Ate-010587	Aspergillus terreus	30.97	1.00e-16	81.60
IUUC-Ame-011878	Astyanax mexicanus	83.28	0.00e+00	1506.00
IUUC-Bta-012863	Bos taurus	85.18	0.00e+00	2151.00
IUUC-Bdi-014016	Brachypodium distachyon	40.45	4.00e-14	73.60
IUUC-Bol-015187	Brassica oleracea	38.55	5.00e-11	62.40
IUUC-Bra-017706	Brassica rapa	34.33	4.00e-13	70.10
IUUC-Cel-018490	Caenorhabditis elegans	31.95	2.00e-39	157.00
IUUC-Cja-019012	Callithrix jacchus	88.10	0.00e+00	2150.00
IUUC-Cfa-020272	Canis familiaris	87.16	0.00e+00	2191.00
IUUC-Cpo-021352	Cavia porcellus	81.75	0.00e+00	2591.00
IUUC-Csa-024033	Chlorocebus sabaeus	72.82	0.00e+00	1686.00
IUUC-Cho-024969	Choloepus hoffmanni	76.65	0.00e+00	1701.00
IUUC-Cin-025435	Ciona intestinalis	43.21	0.00e+00	894.00
IUUC-Csv-026290	Ciona savignyi	54.49	0.00e+00	726.00
IUUC-Cgl-026405	Colletotrichum gloeosporioides	51.72	2.00e-13	69.30
IUUC-Cne-026918	Cryptococcus neoformans	33.87	5.00e-39	157.00
IUUC-Cme-027247	Cyanidioschyzon merolae	24.86	1.00e-10	61.20
IUUC-Dre-028623	Danio rerio	74.07	0.00e+00	1877.00
IUUC-Dno-030044	Dasypus novemcinctus	86.90	0.00e+00	2177.00
IUUC-Dor-030272	Dipodomys ordii	82.06	0.00e+00	1947.00
IUUC-Dse-031409	Dothistroma septosporum	29.80	7.00e-20	92.80
IUUC-Dme-032099	Drosophila melanogaster	31.52	7.00e-37	149.00
IUUC-Ete-032927	Echinops telfairi	92.08	0.00e+00	982.00
IUUC-Eca-033469	Equus caballus	87.79	0.00e+00	2178.00
IUUC-Eeu-034977	Erinaceus europaeus	85.00	0.00e+00	1028.00
IUUC-Fca-036419	Felis catus	85.03	0.00e+00	2178.00
IUUC-Fal-037236	Ficedula albicollis	85.43	0.00e+00	2156.00
IUUC-Gmo-039632	Gadus morhua	67.18	0.00e+00	1614.00
IUUC-Gga-040835	Gallus gallus	85.14	0.00e+00	2105.00
IUUC-Gac-041948	Gasterosteus aculeatus	69.14	0.00e+00	1724.00
IUUC-Gma-043381	Glycine max	35.64	2.00e-11	64.30
IUUC-Ggo-045405	Gorilla gorilla	55.15	0.00e+00	1576.00
IUUC-Hsa-045699	Homo sapiens	87.94	0.00e+00	2202.00
IUUC-Hvu-047530	Hordeum vulgare	33.92	2.00e-16	80.10
IUUC-Itr-048773	Ictidomys tridecemlineatus	84.75	0.00e+00	2121.00
IUUC-Kpa-049215	Komagataella pastoris	34.51	8.00e-14	71.20
IUUC-Lch-050502	Latimeria chalumnae	72.92	0.00e+00	1550.00
IUUC-Lpe-051250	Leersia perrieri	41.67	2.00e-14	74.70
IUUC-Loc-052613	Lepisosteus oculatus	78.30	0.00e+00	1894.00
IUUC-Laf-053608	Loxodonta africana	86.56	0.00e+00	2157.00
IUUC-Mcc-055720	Macaca mulatta	87.63	0.00e+00	2169.00
IUUC-Meu-056445	Macropus eugenii	76.44	0.00e+00	1556.00
IUUC-Mtr-057705	Medicago truncatula	36.27	3.00e-12	67.00
IUUC-Mla-059128	Melampsora laricipopulina	28.80	5.00e-40	160.00
IUUC-Mga-059997	Meleagris gallopavo	56.48	0.00e+00	1372.00
IUUC-Mvi-060268	Microbotryum violaceum	29.70	2.00e-41	164.00
IUUC-Mmr-061258	Microcebus murinus	88.10	0.00e+00	2156.00
IUUC-Mdo-062019	Monodelphis domestica	85.27	0.00e+00	2093.00
IUUC-Mmu-063885	Mus musculus	86.05	0.00e+00	2188.00
IUUC-Mac-065649	Musa acuminata	31.79	2.00e-14	74.30
IUUC-Mpu-066431	Mustela putorius furo	62.40	0.00e+00	1226.00
IUUC-Mlu-068190	Myotis lucifugus	63.04	0.00e+00	1241.00
IUUC-Nfi-068419	Neosartorya fischeri	30.04	2.00e-24	108.00
IUUC-Nle-069448	Nomascus leucogenys	79.04	0.00e+00	1102.00
IUUC-Opr-070441	Ochotona princeps	81.06	0.00e+00	1874.00
IUUC-Ont-071752	Oreochromis niloticus	69.77	0.00e+00	1720.00
IUUC-Ocu-073753	Oryctolagus cuniculus	86.17	0.00e+00	2746.00
IUUC-Ogu-078849	Oryza glumaepatula	41.67	2.00e-14	74.70
IUUC-Olo-080259	Oryza longistaminata	41.67	1.00e-14	75.10
IUUC-Ome-081199	Oryza meridionalis	41.67	1.00e-14	75.10
IUUC-Oni-082167	Oryza nivara	41.67	3.00e-14	73.90
IUUC-Oru-084541	Oryza rufipogon	41.67	3.00e-14	73.90
IUUC-Ola-086482	Oryzias latipes	52.40	0.00e+00	1048.00
IUUC-Olu-087698	Ostreococcus lucimarinus	27.85	2.00e-17	84.00
IUUC-Oga-088602	Otolemur garnettii	87.39	0.00e+00	2170.00
IUUC-Oar-090195	Ovis aries	85.36	0.00e+00	2159.00
IUUC-Ptr-091363	Pan troglodytes	88.02	0.00e+00	2204.00
IUUC-Pan-092385	Papio anubis	87.43	0.00e+00	2172.00
IUUC-Psi-093136	Pelodiscus sinensis	54.92	0.00e+00	1285.00
IUUC-Pno-094814	Phaeosphaeria nodorum	48.72	4.00e-16	80.50
IUUC-Pfo-097486	Poecilia formosa	70.33	0.00e+00	1774.00
IUUC-Pab-098281	Pongo abelii	64.74	0.00e+00	1488.00
IUUC-Pop-099501	Populus trichocarpa	34.11	2.00e-09	57.40
IUUC-Pca-100270	Procavia capensis	73.39	0.00e+00	1262.00
IUUC-Pva-102335	Pteropus vampyrus	84.41	0.00e+00	2102.00
IUUC-Pgr-103473	Puccinia graminis	30.43	2.00e-34	141.00
IUUC-Ptt-103973	Puccinia triticina	27.64	5.00e-24	107.00
IUUC-Pte-104059	Pyrenophora teres	47.50	1.00e-15	79.30
IUUC-Pyt-104816	Pyrenophora triticirepentis	47.50	1.00e-15	79.00
IUUC-Rno-106122	Rattus norvegicus	85.15	0.00e+00	2161.00
IUUC-Sce-106303	Saccharomyces cerevisiae	28.25	1.00e-22	102.00
IUUC-Sha-106851	Sarcophilus harrisii	85.65	0.00e+00	2125.00
IUUC-Sja-107675	Schizosaccharomyces japonicus	38.93	2.00e-17	84.70
IUUC-Spo-108370	Schizosaccharomyces pombe	42.86	1.00e-16	81.60
IUUC-Smo-108995	Selaginella moellendorffii	36.62	4.00e-08	52.40
IUUC-Sit-110414	Setaria italica	40.48	2.00e-14	74.30
IUUC-Sar-112978	Sorex araneus	54.90	0.00e+00	649.00
IUUC-Sbi-114170	Sorghum bicolor	40.00	6.00e-15	75.90
IUUC-Sre-115028	Sporisorium reilianum	35.58	2.00e-33	138.00
IUUC-Ssc-115562	Sus scrofa	58.73	0.00e+00	1123.00
IUUC-Tgu-117028	Taeniopygia guttata	85.83	0.00e+00	2184.00
IUUC-Tru-117789	Takifugu rubripes	71.34	0.00e+00	1773.00
IUUC-Tsy-119039	Tarsius syrichta	86.15	0.00e+00	1274.00
IUUC-Tni-119952	Tetraodon nigroviridis	70.06	0.00e+00	1654.00
IUUC-Tca-121631	Theobroma cacao	27.89	6.00e-10	59.30
IUUC-Tae-123242	Triticum aestivum	41.67	3.00e-14	73.90
IUUC-Tur-126623	Triticum urartu	41.67	3.00e-14	73.90
IUUC-Tbe-127754	Tupaia belangeri	77.19	0.00e+00	1524.00
IUUC-Ttr-129178	Tursiops truncatus	87.39	0.00e+00	2152.00
IUUC-Uma-129456	Ustilago maydis	31.78	1.00e-32	135.00
IUUC-Vda-129921	Verticillium dahliae	29.60	1.00e-19	91.70
IUUC-Vpa-130687	Vicugna pacos	81.67	0.00e+00	1046.00
IUUC-Xtr-132905	Xenopus tropicalis	82.65	0.00e+00	2061.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence