iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061848

UUCD1 version

UUC-MoD-01112

Ensembl Protein ID

ENSMODP00000016259.2

UniProt Accession

F7C8N3; F7C8N3_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000013001.3	ENSMODT00000016559.2	ENSMODP00000016259.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.40e-114	381.3	299	924
ULD/UDP/UBQ/UBQ_Other	1.00e-15	57.5	143	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl NlgNtC+mNS+LQcLsn+ +l+e++l+ k++ ++n++np ++kge+++++++l++++w++++++v+pr+++++++++a++fsgy+
   Q: 299  CGLGNLGNTCFMNSALQCLSNTAPLTEYFLKdKYEAEINRDNPLGMKGEIAEAYAELIKQMWSGRNTQVAPRMFKTQVGRFAPQFSGYQ 387
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ k+kp+ e+++++   ++d      a+e++  +n+s+i+d+F+g +ks+++c+ec ++s++++pf++l
   Q: 388  QQDSQELLAFLLDGLHEDLNRVKKKPYLELKDAN--GRPDLvvakeAWENHRLRNDSVIVDTFHGLFKSTLVCPECSKISVTFDPFCYL 474
           ******************************8888..6666666777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p k+++ +e                                                                            
   Q: 475  TLPLPLKKDRTMEvflvsadpqcrptqyrvtvpmmgavsdlcealsklsgiaaenmvvtdvynhrfhkifqmdeglnhimtrddifvye 563
           ********99888**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 564  vcntaedgsecvtfpvyfrerkirqtssssgtvlygqpllisvpkhkltldylyqvicerisryikhplpddsprphldsatyngsngi 652
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 653  cegeeeemehqddskgqatetescstedcsehelgnescqnvpkrvrsqhckkrlftfslvnsygttdinslaadgkllklnsrstvav 741
           ***************************************************************************************** PP
   S: 186  ....................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfs 238
                                                l+dc+e ft+ e+l +++ +yc++ckk+q+a+kk++l++lP+vL++hLkRfs
   Q: 742  dwdtetrclhydeqeseaydkhssmlqpqkkkkttvALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKVLVVHLKRFS 830
           ****************************************************************************************9 PP
   S: 239  fseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkne.kgkWllfdDskVtevkeeevlee 325
           ++++   r k+++ vefp++ L +s+f+++p  +   ++ Y+Liav +H+G ++ GHY+ay+kn+ +gkW++fdDs+V+  +e+++++ 
   Q: 831  YNRY--WRDKLDTVVEFPIRdLHMSEFVCDPAAG---PYVYDLIAVSNHYGAMGVGHYTAYAKNKlNGKWYYFDDSNVSLASEDQIVT- 913
           9885..567*********************9987...8**************************52666*******************. PP
   S: 326  tgstaYvlfYkrr 338
             + aYvlfY+rr
   Q: 914  --KAAYVLFYQRR 924
           ..*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 5    vksldgs.eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk......GkiL.eddktLadyglkdgstihllekksg 75
           ++++d +  l+++++++dt+a++ ++++k+++ip +++ rL++k       + L ++d+t++d gl++g+++++++++++
   Q: 143  CENSDPTnMLSCHFSKADTIATIEKEMRKLFNIPdERETRLWNKymsntyEQ-LsKPDNTVQDAGLYQGQVLVIEPQNED 221
           67888888899***********************999*****9999977444.46********************99986 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAEGGGCGQR PDAETQKSEL GALMRTALQR GAQWYLIDSR WFKQWKKYVG FDSWDMYNVG 60
ENNLFPGPID NSGLFSDPES QTLKEHLIDE LDYVLVPTEA WNKLVNWYGC VEGQQPIVRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAAG GCGGAGGCTG CGGGCAGCGG CCGGACGCGG AGACCCAGAA ATCTGAGCTC 60
GGGGCCCTGA TGAGGACGGC GCTTCAGCGA GGGGCACAGT GGTGAGAGCG CGAACCCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mdo:100021067

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	41.68	9.00e-121	427.00
IUUC-Aml-001597	Ailuropoda melanoleuca	83.78	0.00e+00	1550.00
IUUC-Atr-002675	Amborella trichopoda	39.21	2.00e-108	387.00
IUUC-Apl-004068	Anas platyrhynchos	71.95	0.00e+00	1244.00
IUUC-Aca-004459	Anolis carolinensis	70.49	0.00e+00	1286.00
IUUC-Ang-009562	Aspergillus niger	44.44	8.00e-55	209.00
IUUC-Ate-010323	Aspergillus terreus	43.32	1.00e-53	205.00
IUUC-Bta-012929	Bos taurus	83.99	0.00e+00	1587.00
IUUC-Bdi-014013	Brachypodium distachyon	37.09	2.00e-153	536.00
IUUC-Bol-015244	Brassica oleracea	37.29	5.00e-155	541.00
IUUC-Bra-016885	Brassica rapa	36.72	8.00e-153	534.00
IUUC-Cja-018798	Callithrix jacchus	85.03	0.00e+00	1548.00
IUUC-Cfa-020599	Canis familiaris	84.50	0.00e+00	1586.00
IUUC-Cpo-022144	Cavia porcellus	81.82	0.00e+00	1494.00
IUUC-Csa-023770	Chlorocebus sabaeus	84.45	0.00e+00	1461.00
IUUC-Cho-024595	Choloepus hoffmanni	73.78	0.00e+00	982.00
IUUC-Cin-025292	Ciona intestinalis	43.46	0.00e+00	756.00
IUUC-Csv-026109	Ciona savignyi	47.73	1.00e-150	527.00
IUUC-Cne-026852	Cryptococcus neoformans	40.06	6.00e-72	266.00
IUUC-Dre-027869	Danio rerio	70.26	0.00e+00	905.00
IUUC-Dno-029316	Dasypus novemcinctus	83.47	0.00e+00	1585.00
IUUC-Dor-031038	Dipodomys ordii	81.95	0.00e+00	806.00
IUUC-Ete-032970	Echinops telfairi	79.12	0.00e+00	961.00
IUUC-Eca-034012	Equus caballus	84.71	0.00e+00	1565.00
IUUC-Eeu-035158	Erinaceus europaeus	71.86	0.00e+00	735.00
IUUC-Fca-035373	Felis catus	81.37	0.00e+00	1560.00
IUUC-Fal-037634	Ficedula albicollis	75.00	0.00e+00	1345.00
IUUC-Fox-037986	Fusarium oxysporum	44.69	1.00e-62	235.00
IUUC-Gmo-038866	Gadus morhua	66.32	0.00e+00	1172.00
IUUC-Gga-040729	Gallus gallus	69.96	0.00e+00	1284.00
IUUC-Gac-042631	Gasterosteus aculeatus	70.05	0.00e+00	1250.00
IUUC-Gma-043077	Glycine max	35.82	2.00e-148	520.00
IUUC-Ggo-045337	Gorilla gorilla	84.84	0.00e+00	1400.00
IUUC-Hsa-045669	Homo sapiens	84.71	0.00e+00	1568.00
IUUC-Hvu-047108	Hordeum vulgare	40.96	1.00e-122	434.00
IUUC-Itr-048610	Ictidomys tridecemlineatus	84.40	0.00e+00	1588.00
IUUC-Lch-050533	Latimeria chalumnae	69.21	0.00e+00	1223.00
IUUC-Lpe-051424	Leersia perrieri	36.96	3.00e-151	529.00
IUUC-Laf-053803	Loxodonta africana	84.40	0.00e+00	1597.00
IUUC-Mcc-055556	Macaca mulatta	81.30	0.00e+00	1476.00
IUUC-Meu-056742	Macropus eugenii	81.70	0.00e+00	1550.00
IUUC-Mor-056985	Magnaporthe oryzae	40.58	3.00e-61	231.00
IUUC-Mpo-057486	Magnaporthe poae	43.59	3.00e-61	231.00
IUUC-Mtr-058563	Medicago truncatula	33.99	1.00e-132	468.00
IUUC-Mga-059300	Meleagris gallopavo	72.38	0.00e+00	1244.00
IUUC-Mmu-063960	Mus musculus	81.40	0.00e+00	1518.00
IUUC-Mpu-066920	Mustela putorius furo	84.30	0.00e+00	1581.00
IUUC-Mlu-068088	Myotis lucifugus	83.68	0.00e+00	1568.00
IUUC-Ncr-068879	Neurospora crassa	30.28	5.00e-66	246.00
IUUC-Nle-070010	Nomascus leucogenys	84.71	0.00e+00	1568.00
IUUC-Opr-070740	Ochotona princeps	81.11	0.00e+00	1107.00
IUUC-Oan-073363	Ornithorhynchus anatinus	79.21	0.00e+00	1488.00
IUUC-Ocu-074242	Oryctolagus cuniculus	79.77	0.00e+00	1482.00
IUUC-Oba-075553	Oryza barthii	42.50	3.00e-130	459.00
IUUC-Obr-076902	Oryza brachyantha	37.41	3.00e-151	529.00
IUUC-Ogl-077583	Oryza glaberrima	42.50	3.00e-130	459.00
IUUC-Ogu-077990	Oryza glumaepatula	42.02	2.00e-125	443.00
IUUC-Oin-079300	Oryza indica	42.66	3.00e-131	462.00
IUUC-Olo-080315	Oryza longistaminata	36.92	3.00e-147	516.00
IUUC-Oni-082303	Oryza nivara	41.86	3.00e-125	442.00
IUUC-Opu-083691	Oryza punctata	35.74	2.00e-144	506.00
IUUC-Oru-085141	Oryza rufipogon	42.28	1.00e-127	451.00
IUUC-Osa-086139	Oryza sativa	36.81	1.00e-148	520.00
IUUC-Ola-086553	Oryzias latipes	68.62	0.00e+00	1292.00
IUUC-Olu-087717	Ostreococcus lucimarinus	40.00	8.00e-126	444.00
IUUC-Oga-088562	Otolemur garnettii	77.95	0.00e+00	1388.00
IUUC-Oar-090439	Ovis aries	83.47	0.00e+00	1565.00
IUUC-Ptr-090801	Pan troglodytes	84.81	0.00e+00	1566.00
IUUC-Pan-092717	Papio anubis	80.33	0.00e+00	1443.00
IUUC-Psi-093942	Pelodiscus sinensis	75.48	0.00e+00	1336.00
IUUC-Pab-098522	Pongo abelii	80.73	0.00e+00	1101.00
IUUC-Pop-099801	Populus trichocarpa	37.69	2.00e-154	540.00
IUUC-Pca-100161	Procavia capensis	76.55	0.00e+00	1372.00
IUUC-Ppe-101587	Prunus persica	37.97	3.00e-150	526.00
IUUC-Rno-106081	Rattus norvegicus	82.02	0.00e+00	1542.00
IUUC-Sha-106937	Sarcophilus harrisii	95.06	0.00e+00	1761.00
IUUC-Smo-108736	Selaginella moellendorffii	50.75	1.00e-73	270.00
IUUC-Sly-111746	Solanum lycopersicum	38.27	3.00e-154	539.00
IUUC-Stu-112671	Solanum tuberosum	38.03	6.00e-153	535.00
IUUC-Sar-113542	Sorex araneus	80.17	0.00e+00	1503.00
IUUC-Sbi-114874	Sorghum bicolor	35.68	3.00e-144	506.00
IUUC-Ssc-115637	Sus scrofa	84.30	0.00e+00	1583.00
IUUC-Tgu-117267	Taeniopygia guttata	72.70	0.00e+00	1335.00
IUUC-Tca-121001	Theobroma cacao	35.91	7.00e-155	541.00
IUUC-Tae-123874	Triticum aestivum	41.92	5.00e-127	448.00
IUUC-Tur-126478	Triticum urartu	41.37	8.00e-123	434.00
IUUC-Tbe-127669	Tupaia belangeri	64.36	0.00e+00	810.00
IUUC-Ttr-128778	Tursiops truncatus	82.85	0.00e+00	1551.00
IUUC-Vpa-130571	Vicugna pacos	89.19	0.00e+00	1062.00
IUUC-Vvi-131010	Vitis vinifera	38.88	3.00e-151	529.00
IUUC-Xtr-132305	Xenopus tropicalis	70.00	0.00e+00	1305.00
IUUC-Yli-134392	Yarrowia lipolytica	41.58	1.00e-61	232.00
IUUC-Zma-135699	Zea mays	35.90	1.00e-144	507.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence