iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-057849

Ensembl Protein ID

AES89393

UniProt Accession

G7JNF2; G7JNF2_MEDTR

Genbank Protein ID

AES89393.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

CM001220

Gene Name

MTR_4g073370

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_4g073370	AES89393	AES89393

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.00e-98	330.3	1484	1880

Active Site

Position(s)	Description	Evidence
1848	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.................................... 65
           s++k++leve+ gE g++l G+t+ef++lls++lq+  l++++  ++  e    +++++                                        
   Q: 1484 SSQKAVLEVEYFGEVGTGL-GPTLEFYTLLSHDLQKVGLQMWRSGSDHMEI-DGDEKKKK--Ssegniardgelvqaplglfprpwpanadasegsqlf 1578
           67899**************.**********************554443222.22222222..1235666778888889********************* PP
   S: 66   ehlklFeflGrllgkalqdgrlldlplsksfyklllgkklsledleevdpelykslkeikena......es.................dieelgldltf 141
           +++++F++lGr+++kalqdgrlldlpls +fykl+lg++l+l+d+  vd+el k+l+e+++++      es                  i +  l+l f
   Q: 1579 KVIEYFRLLGRVVAKALQDGRLLDLPLSVAFYKLVLGQDLDLHDILYVDAELGKTLQELNALVcrkhniESigggntgtvsnlhyrgaPIAD--LCLDF 1675
           ************************************************************99987665511455555555555555334444..44444 PP
   S: 142  svseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggy 239
           +     l+ + e+ Lkpg+e ++ +  N+e+Y++ vv++++k+gi++q+eafr+Gfn+v+++++l++Ft++el++l+cG+ e ++ e+l++++k+++gy
   Q: 1676 T-----LPGYPEYTLKPGDEIVDLN--NLEDYISMVVDATVKTGITRQLEAFRAGFNQVFDISSLQIFTPHELDYLLCGRrELWKTETLADHIKFDHGY 1767
           4.....89**********9876666..*****************************************************999**************** PP
   S: 240  tedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk................dasddrlPssnTCfnyLkLPeYsskeilkek 322
           t++spai +++e++ ef+ e+++af+qFvTg ++lP+gG+a l+p+l+++rk                +++dd+lPs++TC+nyLkLP+Ys+kei+++k
   Q: 1768 TAKSPAIVNLLEIMGEFTPEQQRAFCQFVTGAPKLPPGGLAVLNPKLTIVRKlsstaanttsngngpsETADDDLPSVMTCANYLKLPPYSTKEIMHKK 1866
           *******************************************************************99999*************************** PP
   S: 323  LlyAieet.kgFel 335
           L+yAi+e+  +F+l
   Q: 1867 LMYAINEGqGSFDL 1880
           ********889987 PP

Organism

Medicago truncatula

Protein Sequence
(Fasta)

METRSRKRAE ASSAAPSSSS SSPKSRSTKR PRLSSSSSST AAAATTTVTA TATPTPTTNT 60
RTRASRTKNT LPPPMDSNNE SSSGSRRRGK NPERDNSDKG KEKEHDVRAR NERDAEKGLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACCAATCCA TCCCACAAAA TAAAAAATAT AAAAATAAAA AGCTCTTCAA GAAACTTACA 60
TATAAAAAAA GCCTCTCACA TTCATTCACC CTTTTATTCA TTCTTCCCCT TTCCCCAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000225--Armadillo
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00185--ARM
SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

mtr:MTR_4g073370

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	63.84	0.00e+00	2018.00
IUUC-Aml-001502	Ailuropoda melanoleuca	37.36	5.00e-117	416.00
IUUC-Atr-002821	Amborella trichopoda	70.67	0.00e+00	2098.00
IUUC-Apl-003531	Anas platyrhynchos	36.33	8.00e-106	379.00
IUUC-Aly-005962	Arabidopsis lyrata	71.73	0.00e+00	2160.00
IUUC-Ath-006636	Arabidopsis thaliana	71.28	0.00e+00	2160.00
IUUC-Ago-007875	Ashbya gossypii	35.07	4.00e-79	289.00
IUUC-Acl-008242	Aspergillus clavatus	42.00	4.00e-112	399.00
IUUC-Afl-008736	Aspergillus flavus	41.37	2.00e-110	394.00
IUUC-Afu-008812	Aspergillus fumigatus	41.92	2.00e-113	404.00
IUUC-Ani-009407	Aspergillus nidulans	41.18	6.00e-109	389.00
IUUC-Ang-009763	Aspergillus niger	41.03	4.00e-105	376.00
IUUC-Aor-009941	Aspergillus oryzae	41.37	5.00e-110	392.00
IUUC-Ate-010459	Aspergillus terreus	36.69	4.00e-93	336.00
IUUC-Ame-011761	Astyanax mexicanus	36.71	3.00e-114	407.00
IUUC-Bgr-012265	Blumeria graminis	39.49	1.00e-102	368.00
IUUC-Bta-013070	Bos taurus	37.36	1.00e-116	414.00
IUUC-Bci-013890	Botrytis cinerea	40.42	1.00e-101	364.00
IUUC-Bdi-014961	Brachypodium distachyon	60.72	0.00e+00	1777.00
IUUC-Bol-015942	Brassica oleracea	70.91	0.00e+00	2169.00
IUUC-Bra-016849	Brassica rapa	70.14	0.00e+00	2171.00
IUUC-Cel-018153	Caenorhabditis elegans	37.28	4.00e-89	323.00
IUUC-Cja-019046	Callithrix jacchus	37.36	3.00e-116	413.00
IUUC-Cfa-020521	Canis familiaris	37.22	2.00e-116	414.00
IUUC-Cpo-021639	Cavia porcellus	37.50	1.00e-115	411.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	52.69	5.00e-139	487.00
IUUC-Csa-023231	Chlorocebus sabaeus	37.36	3.00e-116	414.00
IUUC-Cin-025482	Ciona intestinalis	37.04	9.00e-97	347.00
IUUC-Csv-026121	Ciona savignyi	33.66	5.00e-99	356.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	36.80	4.00e-113	403.00
IUUC-Cne-026857	Cryptococcus neoformans	39.38	2.00e-93	337.00
IUUC-Cme-027226	Cyanidioschyzon merolae	31.20	4.00e-78	286.00
IUUC-Dre-028174	Danio rerio	37.14	1.00e-115	411.00
IUUC-Dor-030939	Dipodomys ordii	34.13	2.00e-93	337.00
IUUC-Dse-031444	Dothistroma septosporum	34.45	2.00e-106	380.00
IUUC-Dme-031739	Drosophila melanogaster	34.03	1.00e-87	318.00
IUUC-Ete-032345	Echinops telfairi	32.30	1.00e-83	305.00
IUUC-Eca-033229	Equus caballus	37.36	7.00e-115	409.00
IUUC-Eeu-035205	Erinaceus europaeus	37.38	6.00e-114	405.00
IUUC-Fca-036444	Felis catus	37.32	2.00e-114	407.00
IUUC-Fal-037131	Ficedula albicollis	37.50	8.00e-117	415.00
IUUC-Fox-038035	Fusarium oxysporum	40.03	1.00e-111	396.00
IUUC-Fso-038320	Fusarium solani	39.22	1.00e-111	398.00
IUUC-Gmo-039497	Gadus morhua	36.64	3.00e-115	410.00
IUUC-Ggr-040057	Gaeumannomyces graminis	40.28	4.00e-109	389.00
IUUC-Gga-041021	Gallus gallus	37.50	2.00e-116	414.00
IUUC-Gac-042474	Gasterosteus aculeatus	37.14	5.00e-115	409.00
IUUC-Gma-043060	Glycine max	85.76	0.00e+00	2704.00
IUUC-Ggo-044855	Gorilla gorilla	37.36	3.00e-116	413.00
IUUC-Hsa-046147	Homo sapiens	37.36	2.00e-116	414.00
IUUC-Hvu-047775	Hordeum vulgare	65.56	0.00e+00	2036.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	37.50	9.00e-116	412.00
IUUC-Kpa-049098	Komagataella pastoris	39.00	2.00e-87	317.00
IUUC-Lch-049818	Latimeria chalumnae	36.17	6.00e-108	385.00
IUUC-Lpe-051017	Leersia perrieri	63.46	0.00e+00	1813.00
IUUC-Loc-051777	Lepisosteus oculatus	37.45	7.00e-118	419.00
IUUC-Lma-052990	Leptosphaeria maculans	39.59	3.00e-107	383.00
IUUC-Laf-053727	Loxodonta africana	37.78	6.00e-117	416.00
IUUC-Mcc-055799	Macaca mulatta	37.36	2.00e-116	414.00
IUUC-Meu-056065	Macropus eugenii	34.91	4.00e-93	337.00
IUUC-Mor-057054	Magnaporthe oryzae	39.08	3.00e-108	387.00
IUUC-Mpo-057417	Magnaporthe poae	41.00	2.00e-110	394.00
IUUC-Mla-058870	Melampsora laricipopulina	40.66	2.00e-93	337.00
IUUC-Mga-059580	Meleagris gallopavo	33.14	4.00e-70	259.00
IUUC-Mvi-060507	Microbotryum violaceum	35.81	2.00e-108	387.00
IUUC-Mmr-060816	Microcebus murinus	37.29	2.00e-115	410.00
IUUC-Mdo-062866	Monodelphis domestica	35.16	4.00e-94	340.00
IUUC-Mmu-063906	Mus musculus	37.36	7.00e-115	409.00
IUUC-Mac-065153	Musa acuminata	67.14	0.00e+00	1037.00
IUUC-Mpu-066199	Mustela putorius furo	37.36	8.00e-117	415.00
IUUC-Mlu-067110	Myotis lucifugus	37.64	5.00e-115	409.00
IUUC-Nfi-068482	Neosartorya fischeri	42.27	2.00e-114	407.00
IUUC-Ncr-068906	Neurospora crassa	39.55	3.00e-109	390.00
IUUC-Nle-069410	Nomascus leucogenys	37.36	2.00e-116	414.00
IUUC-Opr-070401	Ochotona princeps	39.25	1.00e-47	186.00
IUUC-Ont-072100	Oreochromis niloticus	36.93	1.00e-116	414.00
IUUC-Oan-073121	Ornithorhynchus anatinus	37.09	4.00e-115	409.00
IUUC-Ocu-074623	Oryctolagus cuniculus	37.36	3.00e-116	413.00
IUUC-Oba-074990	Oryza barthii	61.79	0.00e+00	1738.00
IUUC-Obr-076915	Oryza brachyantha	61.34	0.00e+00	951.00
IUUC-Ogl-077055	Oryza glaberrima	60.62	0.00e+00	1762.00
IUUC-Ogu-078685	Oryza glumaepatula	61.69	0.00e+00	1740.00
IUUC-Oin-079256	Oryza indica	62.87	0.00e+00	1828.00
IUUC-Olo-080343	Oryza longistaminata	62.87	0.00e+00	1825.00
IUUC-Ome-081422	Oryza meridionalis	62.78	0.00e+00	1855.00
IUUC-Oni-082469	Oryza nivara	62.03	0.00e+00	1803.00
IUUC-Opu-083792	Oryza punctata	61.39	0.00e+00	1791.00
IUUC-Oru-084607	Oryza rufipogon	61.57	0.00e+00	1740.00
IUUC-Osa-085972	Oryza sativa	69.90	0.00e+00	953.00
IUUC-Ola-087173	Oryzias latipes	37.07	3.00e-116	413.00
IUUC-Olu-087871	Ostreococcus lucimarinus	46.74	1.00e-132	465.00
IUUC-Oga-087908	Otolemur garnettii	37.36	9.00e-116	412.00
IUUC-Oar-090277	Ovis aries	37.36	1.00e-116	414.00
IUUC-Ptr-091543	Pan troglodytes	37.36	2.00e-116	414.00
IUUC-Pan-092243	Papio anubis	37.36	2.00e-116	414.00
IUUC-Psi-093150	Pelodiscus sinensis	37.16	1.00e-115	411.00
IUUC-Pno-094891	Phaeosphaeria nodorum	39.38	3.00e-109	390.00
IUUC-Ppa-095181	Physcomitrella patens	59.53	0.00e+00	736.00
IUUC-Pfo-096267	Poecilia formosa	36.35	5.00e-114	406.00
IUUC-Pab-098072	Pongo abelii	37.36	3.00e-116	413.00
IUUC-Pop-099190	Populus trichocarpa	75.61	0.00e+00	2362.00
IUUC-Pca-100311	Procavia capensis	37.93	3.00e-116	413.00
IUUC-Ppe-101284	Prunus persica	81.02	0.00e+00	2507.00
IUUC-Pva-102215	Pteropus vampyrus	37.61	1.00e-95	345.00
IUUC-Pgr-103694	Puccinia graminis	41.17	1.00e-95	345.00
IUUC-Ptt-103916	Puccinia triticina	39.42	1.00e-88	321.00
IUUC-Pte-104346	Pyrenophora teres	39.49	4.00e-110	392.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	40.00	2.00e-110	394.00
IUUC-Rno-105315	Rattus norvegicus	37.64	5.00e-116	412.00
IUUC-Sha-106835	Sarcophilus harrisii	37.24	1.00e-114	408.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	39.84	1.00e-97	351.00
IUUC-Spo-108081	Schizosaccharomyces pombe	39.18	2.00e-90	327.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	40.76	3.00e-105	377.00
IUUC-Smo-108776	Selaginella moellendorffii	62.31	0.00e+00	795.00
IUUC-Sit-110717	Setaria italica	62.62	0.00e+00	1854.00
IUUC-Sly-111469	Solanum lycopersicum	72.71	0.00e+00	2329.00
IUUC-Stu-112009	Solanum tuberosum	67.46	0.00e+00	1165.00
IUUC-Sbi-114313	Sorghum bicolor	65.15	0.00e+00	2080.00
IUUC-Sre-114993	Sporisorium reilianum	35.72	8.00e-100	359.00
IUUC-Ssc-115535	Sus scrofa	35.08	5.00e-99	356.00
IUUC-Tgu-117493	Taeniopygia guttata	33.14	6.00e-70	259.00
IUUC-Tru-118669	Takifugu rubripes	37.01	1.00e-114	408.00
IUUC-Tsy-119373	Tarsius syrichta	32.65	9.00e-79	288.00
IUUC-Tni-120049	Tetraodon nigroviridis	36.69	3.00e-86	311.00
IUUC-Tca-121779	Theobroma cacao	78.79	0.00e+00	2504.00
IUUC-Tre-122195	Trichoderma reesei	36.19	2.00e-108	387.00
IUUC-Tvi-122650	Trichoderma virens	36.30	1.00e-107	384.00
IUUC-Tae-123120	Triticum aestivum	62.65	0.00e+00	1869.00
IUUC-Tur-126295	Triticum urartu	64.10	0.00e+00	1982.00
IUUC-Tme-126964	Tuber melanosporum	41.60	2.00e-111	397.00
IUUC-Ttr-128165	Tursiops truncatus	37.55	3.00e-116	413.00
IUUC-Uma-129365	Ustilago maydis	37.91	5.00e-87	316.00
IUUC-Vda-129725	Verticillium dahliae	42.29	4.00e-113	402.00
IUUC-Vpa-130678	Vicugna pacos	37.36	4.00e-116	413.00
IUUC-Vvi-131147	Vitis vinifera	76.59	0.00e+00	2413.00
IUUC-Xtr-132636	Xenopus tropicalis	36.71	2.00e-109	390.00
IUUC-Xma-133458	Xiphophorus maculatus	36.93	2.00e-116	414.00
IUUC-Yli-134481	Yarrowia lipolytica	40.38	1.00e-102	367.00
IUUC-Zma-135782	Zea mays	63.97	0.00e+00	2050.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence