iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092273

Ensembl Protein ID

ENSPANP00000010459.1

UniProt Accession

A0A096NCB7; A0A096NCB7_PAPAN

Genbank Protein ID

ENSPANP00000010459

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01042621

Gene Name

KLHL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000007135.1	ENSPANT00000025289.1	ENSPANP00000010459.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.80e-21	76.3	56	123
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-11	43.1	156	186

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv++v ++ e++ah++vLaa+S++F+a+f++e++es+  ++v ik+v+   +r l++++Yt +++ +e
   Q: 56   CDVTIVAEDMEISAHRVVLAACSPYFHAMFTGEMSESR-AKRVRIKEVDGWTLRMLIDYVYTAEIQVTE 123
           8*************************************.*************************99765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
            Nclgi++fAd++ c+dL  +a++++++hF+
   Q: 156  VNCLGIRAFADMHACTDLLNKANTYAEQHFT 186
           6*****************************7 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

METPPLPPAC TKQGHQKPLD SKDDNTEKHC PVTVNPWHMK KAFKVMNELR SQNLLCDVTI 60
VAEDMEISAH RVVLAACSPY FHAMFTGEMS ESRAKRVRIK EVDGWTLRML IDYVYTAEIQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGCCGCCG CCCGCGTCCC GGCCTGCGGG CCAGCGTCTG GGCACGCCCG CCCGGCTCCC 60
GGCTGGCGCC CGCCCGCCTC CAGAAGCAGC AGAAACAGCA GCAGCAGCGG TAGCAGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002378	Ailuropoda melanoleuca	98.56	0.00e+00	955.00
IUUC-Cja-018942	Callithrix jacchus	98.36	0.00e+00	954.00
IUUC-Cfa-020886	Canis familiaris	99.58	0.00e+00	955.00
IUUC-Cpo-022543	Cavia porcellus	99.39	0.00e+00	973.00
IUUC-Csa-023088	Chlorocebus sabaeus	100.00	0.00e+00	978.00
IUUC-Dno-029873	Dasypus novemcinctus	96.91	0.00e+00	931.00
IUUC-Dse-031229	Dothistroma septosporum	37.14	3.00e-08	52.00
IUUC-Eca-033798	Equus caballus	98.54	0.00e+00	947.00
IUUC-Fca-036455	Felis catus	99.58	0.00e+00	955.00
IUUC-Ggo-044620	Gorilla gorilla	92.98	0.00e+00	893.00
IUUC-Hsa-046265	Homo sapiens	99.59	0.00e+00	975.00
IUUC-Laf-053800	Loxodonta africana	99.17	0.00e+00	952.00
IUUC-Mcc-055732	Macaca mulatta	100.00	0.00e+00	958.00
IUUC-Mmr-061067	Microcebus murinus	97.95	0.00e+00	951.00
IUUC-Mdo-062977	Monodelphis domestica	94.29	0.00e+00	928.00
IUUC-Mmu-064035	Mus musculus	98.16	0.00e+00	964.00
IUUC-Mpu-066726	Mustela putorius furo	99.79	0.00e+00	956.00
IUUC-Mlu-067020	Myotis lucifugus	98.55	0.00e+00	951.00
IUUC-Nle-069456	Nomascus leucogenys	98.56	0.00e+00	955.00
IUUC-Opr-071130	Ochotona princeps	86.90	0.00e+00	807.00
IUUC-Ocu-074045	Oryctolagus cuniculus	98.78	0.00e+00	966.00
IUUC-Oga-088494	Otolemur garnettii	97.96	0.00e+00	954.00
IUUC-Oar-089645	Ovis aries	97.75	0.00e+00	951.00
IUUC-Ptr-091063	Pan troglodytes	99.59	0.00e+00	969.00
IUUC-Psi-093946	Pelodiscus sinensis	93.79	0.00e+00	935.00
IUUC-Pab-097768	Pongo abelii	99.39	0.00e+00	974.00
IUUC-Pca-100607	Procavia capensis	81.22	0.00e+00	754.00
IUUC-Pva-102218	Pteropus vampyrus	91.84	0.00e+00	881.00
IUUC-Rno-105250	Rattus norvegicus	97.96	0.00e+00	960.00
IUUC-Sar-113249	Sorex araneus	98.75	0.00e+00	947.00
IUUC-Ssc-115423	Sus scrofa	98.56	0.00e+00	955.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence