iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108273

Ensembl Protein ID

SPAC1952.05.1:pep

UniProt Accession

Q9UUK2; GCN5_SCHPO

Genbank Protein ID

BAD11106.1; CAB52569.1

Protein Name

Histone acetyltransferase gcn5

Genbank Nucleotide ID

AB162439; CU329670

Gene Name

gcn5; SPAC1952.05

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC1952.05	SPAC1952.05.1	SPAC1952.05.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	48.17	4.00e-92	336.00	IUUC-Hsa-046970

Active Site

Position(s)	Description	Evidence
191	Proton donor/acceptor	{ECO:0000250\|UniProtKB:Q92830}

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H3 to form H3K14ac, and with a lower preference histone H4 to form H4K8ac and H4K16ac. Acetylation of histones gives a specific tag for epigenetic transcription activation (By similarity).

Protein Sequence
(Fasta)

MSNSLNDQTR PPDSSVVDST SSNFPNASND SVHDKPVKQD EQSNPNVREA IANSDGQESL 60
AVKENKDTES SSSHFVPNGV SNSKKRKLVA TDLDVDFDIS SVRVTEKPSV LEEKSGVIQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAAAATGA AAGCAGAAAA TTCGTAGAGA AGAAATTTTC TAATCTTGCA TCCCAAGTCA 60
AATCATGTAT TTGTGTCTTT AATTAGTAAA TATTAGGATA ATCGTTGATT TGAAGTATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0010--Activator
KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR000182--GNAT_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51186--GNAT

Pfam

PF00583--Acetyltransf_1
PF00439--Bromodomain

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO

Gene Ontology

GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0000124--C:SAGA complex
GO:0010484--F:H3 histone acetyltransferase activity
GO:0006338--P:chromatin remodeling
GO:0043966--P:histone H3 acetylation
GO:0060358--P:negative regulation of leucine import
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0007131--P:reciprocal meiotic recombination
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated

KEGG

spo:SPAC1952.05

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001599	Ailuropoda melanoleuca	49.11	6.00e-85	306.00
IUUC-Atr-003130	Amborella trichopoda	43.25	2.00e-92	330.00
IUUC-Apl-004026	Anas platyrhynchos	49.11	2.00e-90	325.00
IUUC-Aca-005148	Anolis carolinensis	47.87	3.00e-24	105.00
IUUC-Aly-006486	Arabidopsis lyrata	43.84	8.00e-81	292.00
IUUC-Ath-006763	Arabidopsis thaliana	43.84	6.00e-81	293.00
IUUC-Ago-007819	Ashbya gossypii	64.27	7.00e-146	508.00
IUUC-Acl-008194	Aspergillus clavatus	56.27	5.00e-132	461.00
IUUC-Afl-008546	Aspergillus flavus	60.47	4.00e-130	455.00
IUUC-Afu-009124	Aspergillus fumigatus	61.63	1.00e-132	464.00
IUUC-Ani-009432	Aspergillus nidulans	60.49	6.00e-123	431.00
IUUC-Ang-009824	Aspergillus niger	56.06	9.00e-134	468.00
IUUC-Aor-010076	Aspergillus oryzae	59.28	9.00e-130	454.00
IUUC-Ame-010924	Astyanax mexicanus	47.87	2.00e-24	107.00
IUUC-Bgr-012003	Blumeria graminis	54.19	1.00e-119	420.00
IUUC-Bta-012381	Bos taurus	49.11	6.00e-90	323.00
IUUC-Bci-013974	Botrytis cinerea	48.73	4.00e-122	429.00
IUUC-Bdi-015016	Brachypodium distachyon	44.82	2.00e-90	324.00
IUUC-Bol-015982	Brassica oleracea	40.68	7.00e-09	55.50
IUUC-Bra-016868	Brassica rapa	42.62	2.00e-09	57.40
IUUC-Cel-018633	Caenorhabditis elegans	39.29	1.00e-71	262.00
IUUC-Cja-019375	Callithrix jacchus	49.11	4.00e-85	306.00
IUUC-Cfa-020400	Canis familiaris	49.11	7.00e-85	306.00
IUUC-Cpo-021686	Cavia porcellus	49.11	2.00e-90	325.00
IUUC-Cre-023019	Chlamydomonas reinhardtii	37.72	7.00e-80	289.00
IUUC-Csa-024252	Chlorocebus sabaeus	49.41	6.00e-91	326.00
IUUC-Cho-024635	Choloepus hoffmanni	56.49	3.00e-39	154.00
IUUC-Cin-025450	Ciona intestinalis	40.78	2.00e-22	98.60
IUUC-Csv-026235	Ciona savignyi	40.00	7.00e-20	88.20
IUUC-Cgl-026660	Colletotrichum gloeosporioides	59.20	1.00e-124	437.00
IUUC-Cne-027050	Cryptococcus neoformans	50.94	9.00e-102	362.00
IUUC-Dre-027468	Danio rerio	48.07	1.00e-88	318.00
IUUC-Dno-029306	Dasypus novemcinctus	49.11	3.00e-90	324.00
IUUC-Dor-030465	Dipodomys ordii	39.72	1.00e-48	186.00
IUUC-Dse-031386	Dothistroma septosporum	54.27	4.00e-115	405.00
IUUC-Dme-032140	Drosophila melanogaster	48.94	2.00e-24	107.00
IUUC-Ete-032789	Echinops telfairi	46.81	4.00e-23	103.00
IUUC-Eca-034212	Equus caballus	49.11	5.00e-85	306.00
IUUC-Eeu-034605	Erinaceus europaeus	39.58	5.00e-62	230.00
IUUC-Fca-035972	Felis catus	49.11	3.00e-90	324.00
IUUC-Fal-037223	Ficedula albicollis	47.34	2.00e-89	321.00
IUUC-Fox-037874	Fusarium oxysporum	57.39	4.00e-120	422.00
IUUC-Fso-038286	Fusarium solani	57.46	1.00e-122	431.00
IUUC-Gmo-039102	Gadus morhua	46.63	6.00e-86	310.00
IUUC-Ggr-039925	Gaeumannomyces graminis	51.00	3.00e-120	423.00
IUUC-Gga-041181	Gallus gallus	49.11	7.00e-91	326.00
IUUC-Gac-041887	Gasterosteus aculeatus	46.63	1.00e-84	305.00
IUUC-Gma-043540	Glycine max	46.26	3.00e-91	327.00
IUUC-Ggo-044607	Gorilla gorilla	49.41	4.00e-91	327.00
IUUC-Hsa-046970	Homo sapiens	49.41	4.00e-91	327.00
IUUC-Hvu-047105	Hordeum vulgare	56.18	7.00e-59	218.00
IUUC-Itr-048740	Ictidomys tridecemlineatus	47.87	8.00e-24	105.00
IUUC-Kpa-049146	Komagataella pastoris	56.58	5.00e-140	488.00
IUUC-Lch-049478	Latimeria chalumnae	48.22	2.00e-88	318.00
IUUC-Lpe-051678	Leersia perrieri	47.65	1.00e-81	295.00
IUUC-Loc-052255	Lepisosteus oculatus	46.89	1.00e-89	322.00
IUUC-Laf-054575	Loxodonta africana	49.11	6.00e-85	306.00
IUUC-Mcc-055161	Macaca mulatta	49.41	6.00e-91	326.00
IUUC-Meu-055990	Macropus eugenii	43.66	6.00e-14	71.60
IUUC-Mor-057026	Magnaporthe oryzae	52.91	8.00e-116	408.00
IUUC-Mpo-057590	Magnaporthe poae	55.87	5.00e-120	422.00
IUUC-Mtr-057835	Medicago truncatula	47.51	4.00e-90	322.00
IUUC-Mla-058950	Melampsora laricipopulina	55.93	8.00e-107	378.00
IUUC-Mga-060204	Meleagris gallopavo	47.87	6.00e-23	102.00
IUUC-Mvi-060295	Microbotryum violaceum	60.73	6.00e-125	439.00
IUUC-Mmr-060643	Microcebus murinus	47.63	1.00e-85	309.00
IUUC-Mdo-062732	Monodelphis domestica	48.52	1.00e-89	322.00
IUUC-Mmu-064125	Mus musculus	49.70	1.00e-86	311.00
IUUC-Mac-064798	Musa acuminata	43.08	8.00e-11	62.00
IUUC-Mpu-066371	Mustela putorius furo	49.41	7.00e-91	326.00
IUUC-Mlu-067447	Myotis lucifugus	48.52	4.00e-89	320.00
IUUC-Nfi-068373	Neosartorya fischeri	61.30	7.00e-135	471.00
IUUC-Ncr-068652	Neurospora crassa	57.75	3.00e-122	429.00
IUUC-Nle-069659	Nomascus leucogenys	49.41	4.00e-91	327.00
IUUC-Opr-070678	Ochotona princeps	47.46	3.00e-13	69.30
IUUC-Ont-071244	Oreochromis niloticus	47.77	4.00e-87	313.00
IUUC-Oan-072794	Ornithorhynchus anatinus	48.82	1.00e-89	321.00
IUUC-Ocu-074701	Oryctolagus cuniculus	49.11	7.00e-85	306.00
IUUC-Oba-075479	Oryza barthii	50.64	1.00e-67	248.00
IUUC-Obr-076214	Oryza brachyantha	35.14	6.00e-10	58.90
IUUC-Ogl-076970	Oryza glaberrima	46.84	2.00e-83	301.00
IUUC-Ogu-079017	Oryza glumaepatula	35.62	3.00e-10	60.10
IUUC-Oin-079610	Oryza indica	50.64	2.00e-67	248.00
IUUC-Olo-080777	Oryza longistaminata	35.62	2.00e-10	60.10
IUUC-Ome-081474	Oryza meridionalis	35.62	3.00e-10	60.10
IUUC-Oni-083016	Oryza nivara	46.18	2.00e-82	298.00
IUUC-Opu-083976	Oryza punctata	47.84	3.00e-84	303.00
IUUC-Oru-085067	Oryza rufipogon	35.62	2.00e-10	60.10
IUUC-Osa-085814	Oryza sativa	46.84	2.00e-83	301.00
IUUC-Ola-087071	Oryzias latipes	47.63	4.00e-87	314.00
IUUC-Olu-087711	Ostreococcus lucimarinus	40.86	1.00e-78	285.00
IUUC-Oga-089043	Otolemur garnettii	49.11	2.00e-85	308.00
IUUC-Oar-089893	Ovis aries	48.82	7.00e-90	323.00
IUUC-Ptr-090629	Pan troglodytes	49.41	4.00e-91	327.00
IUUC-Pan-092305	Papio anubis	47.94	1.00e-89	322.00
IUUC-Psi-093574	Pelodiscus sinensis	47.20	3.00e-87	313.00
IUUC-Pma-094160	Petromyzon marinus	48.22	4.00e-90	324.00
IUUC-Ppa-095410	Physcomitrella patens	45.87	6.00e-83	299.00
IUUC-Pfo-097043	Poecilia formosa	40.92	2.00e-87	315.00
IUUC-Pab-098748	Pongo abelii	49.41	7.00e-91	326.00
IUUC-Pop-099371	Populus trichocarpa	41.67	3.00e-08	53.10
IUUC-Pca-100223	Procavia capensis	48.82	2.00e-88	318.00
IUUC-Ppe-101832	Prunus persica	47.26	6.00e-94	336.00
IUUC-Pva-102122	Pteropus vampyrus	48.82	6.00e-85	306.00
IUUC-Pte-104228	Pyrenophora teres	54.25	9.00e-116	407.00
IUUC-Pyt-104702	Pyrenophora triticirepentis	49.37	3.00e-116	409.00
IUUC-Rno-105749	Rattus norvegicus	46.53	4.00e-24	106.00
IUUC-Sce-106432	Saccharomyces cerevisiae	62.30	7.00e-144	501.00
IUUC-Sha-107338	Sarcophilus harrisii	48.82	1.00e-89	322.00
IUUC-Ssl-108545	Sclerotinia sclerotiorum	51.41	8.00e-116	408.00
IUUC-Smo-109385	Selaginella moellendorffii	41.36	3.00e-85	306.00
IUUC-Sit-110222	Setaria italica	47.41	4.00e-86	309.00
IUUC-Sly-111498	Solanum lycopersicum	55.45	1.00e-66	244.00
IUUC-Sar-113574	Sorex araneus	49.11	3.00e-84	304.00
IUUC-Sbi-114471	Sorghum bicolor	47.84	1.00e-86	311.00
IUUC-Sre-114915	Sporisorium reilianum	58.08	7.00e-132	462.00
IUUC-Ssc-116097	Sus scrofa	49.11	1.00e-84	305.00
IUUC-Tgu-116699	Taeniopygia guttata	48.82	1.00e-89	322.00
IUUC-Tru-118001	Takifugu rubripes	46.47	1.00e-84	306.00
IUUC-Tsy-118910	Tarsius syrichta	43.49	2.00e-71	261.00
IUUC-Tni-119684	Tetraodon nigroviridis	46.88	2.00e-85	308.00
IUUC-Tca-121066	Theobroma cacao	45.11	6.00e-90	322.00
IUUC-Tre-122112	Trichoderma reesei	56.74	1.00e-122	431.00
IUUC-Tvi-122355	Trichoderma virens	56.74	2.00e-122	430.00
IUUC-Tae-123931	Triticum aestivum	44.82	5.00e-82	296.00
IUUC-Tur-126587	Triticum urartu	44.88	3.00e-81	293.00
IUUC-Tme-126963	Tuber melanosporum	61.88	2.00e-134	469.00
IUUC-Tbe-127304	Tupaia belangeri	42.60	9.00e-75	272.00
IUUC-Ttr-128536	Tursiops truncatus	49.41	3.00e-85	307.00
IUUC-Uma-129538	Ustilago maydis	57.53	8.00e-132	462.00
IUUC-Vda-129860	Verticillium dahliae	58.45	3.00e-126	442.00
IUUC-Vpa-130239	Vicugna pacos	37.09	8.00e-53	199.00
IUUC-Vvi-130897	Vitis vinifera	45.56	6.00e-93	332.00
IUUC-Xtr-132300	Xenopus tropicalis	48.82	9.00e-91	326.00
IUUC-Xma-134105	Xiphophorus maculatus	46.88	3.00e-86	310.00
IUUC-Yli-134345	Yarrowia lipolytica	60.00	5.00e-141	492.00
IUUC-Zma-135384	Zea mays	46.69	6.00e-85	305.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence