iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067088

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02037211

Gene Name

TOPORS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000003053.2	ENSMLUT00000003054.2	ENSMLUP00000002776.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.00e-09	37.3	102	141

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 102  CPICLDRFDNVSYLDRCLHKFCFRCVQEW------SKNKAECPLCK 141
           **********999999*************......**********7 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

GSQQPPGSPL SREEGEAPPH APTPEGPRRS RRVRLRGSCR HRPGFLGRRE LATSAPARHS 60
PTFSEVMASA AKEYKMDNFS PKAGTSKLQQ TVPADASPDS KCPICLDRFD NVSYLDRCLH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTCGCAAC AGCCGCCGGG GTCTCCGCTG TCTCGCGAGG AGGGTGAAGC GCCCCCGCAC 60
GCTCCGACGC CGGAGGGTCC GCGGAGAAGT CGCCGGGTAC GCCTTCGCGG ATCCTGCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	3.00e-09	55.80
IUUC-Aml-002240	Ailuropoda melanoleuca	89.30	0.00e+00	906.00
IUUC-Atr-002964	Amborella trichopoda	25.45	2.00e-11	62.40
IUUC-Apl-003666	Anas platyrhynchos	58.27	4.00e-142	499.00
IUUC-Aca-005305	Anolis carolinensis	63.45	5.00e-147	515.00
IUUC-Aly-005926	Arabidopsis lyrata	45.76	2.00e-10	59.30
IUUC-Ath-007299	Arabidopsis thaliana	35.79	5.00e-11	61.60
IUUC-Ame-011109	Astyanax mexicanus	52.48	5.00e-113	402.00
IUUC-Bta-012637	Bos taurus	89.87	0.00e+00	919.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	2.00e-11	62.80
IUUC-Bol-015147	Brassica oleracea	43.94	4.00e-09	57.00
IUUC-Bra-017073	Brassica rapa	44.90	2.00e-08	52.40
IUUC-Cja-019105	Callithrix jacchus	91.85	0.00e+00	969.00
IUUC-Cfa-021203	Canis familiaris	89.81	0.00e+00	894.00
IUUC-Cpo-022335	Cavia porcellus	83.51	0.00e+00	850.00
IUUC-Csa-023870	Chlorocebus sabaeus	91.69	0.00e+00	944.00
IUUC-Cho-024870	Choloepus hoffmanni	91.06	0.00e+00	863.00
IUUC-Cne-026788	Cryptococcus neoformans	33.85	5.00e-07	49.70
IUUC-Dre-027535	Danio rerio	50.65	3.00e-118	419.00
IUUC-Dno-028963	Dasypus novemcinctus	89.98	0.00e+00	872.00
IUUC-Dor-030239	Dipodomys ordii	88.78	0.00e+00	769.00
IUUC-Dme-031941	Drosophila melanogaster	31.93	3.00e-36	147.00
IUUC-Ete-032300	Echinops telfairi	81.46	0.00e+00	1084.00
IUUC-Eca-033690	Equus caballus	93.16	0.00e+00	890.00
IUUC-Eeu-035257	Erinaceus europaeus	85.35	0.00e+00	851.00
IUUC-Fca-036383	Felis catus	89.43	0.00e+00	895.00
IUUC-Fal-037209	Ficedula albicollis	68.40	8.00e-158	551.00
IUUC-Gmo-039416	Gadus morhua	52.80	9.00e-116	410.00
IUUC-Gga-041267	Gallus gallus	71.02	2.00e-171	596.00
IUUC-Gac-042227	Gasterosteus aculeatus	50.72	9.00e-116	410.00
IUUC-Gma-043386	Glycine max	36.08	2.00e-11	62.40
IUUC-Ggo-044445	Gorilla gorilla	91.53	0.00e+00	957.00
IUUC-Hsa-045844	Homo sapiens	91.69	0.00e+00	957.00
IUUC-Hvu-047531	Hordeum vulgare	46.00	2.00e-10	56.20
IUUC-Itr-048818	Ictidomys tridecemlineatus	90.15	0.00e+00	922.00
IUUC-Lch-050031	Latimeria chalumnae	67.19	4.00e-166	578.00
IUUC-Lpe-051274	Leersia perrieri	37.74	1.00e-08	53.50
IUUC-Loc-052944	Lepisosteus oculatus	58.55	1.00e-141	496.00
IUUC-Laf-053820	Loxodonta africana	91.14	0.00e+00	845.00
IUUC-Mcc-054800	Macaca mulatta	91.69	0.00e+00	944.00
IUUC-Meu-056806	Macropus eugenii	72.84	0.00e+00	633.00
IUUC-Mtr-058378	Medicago truncatula	34.26	2.00e-12	65.90
IUUC-Mla-059017	Melampsora laricipopulina	36.07	4.00e-09	55.50
IUUC-Mvi-060417	Microbotryum violaceum	25.53	1.00e-17	85.10
IUUC-Mmr-061481	Microcebus murinus	91.97	0.00e+00	897.00
IUUC-Mdo-062219	Monodelphis domestica	76.58	9.00e-108	384.00
IUUC-Mmu-064138	Mus musculus	86.57	0.00e+00	817.00
IUUC-Mac-064635	Musa acuminata	38.57	9.00e-11	59.30
IUUC-Nle-069862	Nomascus leucogenys	91.87	0.00e+00	980.00
IUUC-Opr-071076	Ochotona princeps	88.61	0.00e+00	789.00
IUUC-Ont-072225	Oreochromis niloticus	51.58	3.00e-112	399.00
IUUC-Oan-073069	Ornithorhynchus anatinus	65.60	2.00e-155	542.00
IUUC-Ocu-074826	Oryctolagus cuniculus	89.66	0.00e+00	912.00
IUUC-Oba-075429	Oryza barthii	37.68	2.00e-10	59.70
IUUC-Obr-076084	Oryza brachyantha	36.23	4.00e-10	58.20
IUUC-Ogl-077444	Oryza glaberrima	37.68	2.00e-10	59.70
IUUC-Ogu-078603	Oryza glumaepatula	37.68	2.00e-10	59.70
IUUC-Oin-079777	Oryza indica	37.68	2.00e-10	59.70
IUUC-Oni-082396	Oryza nivara	37.68	2.00e-10	59.70
IUUC-Opu-083698	Oryza punctata	36.62	9.00e-10	57.40
IUUC-Oru-084305	Oryza rufipogon	37.68	2.00e-10	59.70
IUUC-Ola-087377	Oryzias latipes	54.84	9.00e-112	396.00
IUUC-Oga-088059	Otolemur garnettii	88.62	0.00e+00	905.00
IUUC-Oar-089592	Ovis aries	91.60	0.00e+00	880.00
IUUC-Ptr-091233	Pan troglodytes	91.53	0.00e+00	955.00
IUUC-Pan-092743	Papio anubis	91.69	0.00e+00	944.00
IUUC-Psi-093669	Pelodiscus sinensis	57.61	0.00e+00	828.00
IUUC-Ppa-095668	Physcomitrella patens	25.71	1.00e-20	94.40
IUUC-Pfo-096706	Poecilia formosa	52.33	2.00e-106	380.00
IUUC-Pop-098813	Populus trichocarpa	23.83	2.00e-11	62.40
IUUC-Pca-100967	Procavia capensis	88.22	0.00e+00	793.00
IUUC-Ppe-101922	Prunus persica	25.18	6.00e-12	64.30
IUUC-Pva-102982	Pteropus vampyrus	93.38	0.00e+00	927.00
IUUC-Pgr-103551	Puccinia graminis	35.14	8.00e-09	54.30
IUUC-Ptt-103977	Puccinia triticina	32.79	6.00e-07	47.80
IUUC-Rno-105730	Rattus norvegicus	85.32	0.00e+00	773.00
IUUC-Sha-106588	Sarcophilus harrisii	68.58	3.00e-179	622.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	35.82	1.00e-07	50.10
IUUC-Smo-109039	Selaginella moellendorffii	24.70	3.00e-17	82.80
IUUC-Sly-110956	Solanum lycopersicum	23.93	6.00e-09	54.70
IUUC-Stu-111938	Solanum tuberosum	31.58	3.00e-06	45.40
IUUC-Sar-113622	Sorex araneus	89.23	3.00e-159	555.00
IUUC-Sre-115041	Sporisorium reilianum	37.84	1.00e-09	57.00
IUUC-Ssc-115244	Sus scrofa	93.39	0.00e+00	874.00
IUUC-Tgu-117180	Taeniopygia guttata	64.29	2.00e-167	583.00
IUUC-Tru-118393	Takifugu rubripes	54.17	5.00e-120	425.00
IUUC-Tsy-119408	Tarsius syrichta	90.65	0.00e+00	905.00
IUUC-Tni-120664	Tetraodon nigroviridis	56.60	2.00e-120	426.00
IUUC-Tca-121712	Theobroma cacao	27.07	1.00e-16	80.50
IUUC-Tae-122787	Triticum aestivum	38.57	1.00e-10	60.10
IUUC-Tbe-127301	Tupaia belangeri	82.20	0.00e+00	810.00
IUUC-Ttr-128204	Tursiops truncatus	92.01	0.00e+00	954.00
IUUC-Uma-129420	Ustilago maydis	43.24	5.00e-10	58.50
IUUC-Vpa-130297	Vicugna pacos	92.52	0.00e+00	881.00
IUUC-Vvi-131157	Vitis vinifera	25.33	7.00e-17	81.30
IUUC-Xtr-132845	Xenopus tropicalis	67.51	8.00e-169	587.00
IUUC-Xma-133439	Xiphophorus maculatus	52.48	1.00e-109	390.00
IUUC-Yli-134652	Yarrowia lipolytica	38.78	5.00e-06	45.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence