iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066483

Ensembl Protein ID

ENSMPUP00000016240.1

UniProt Accession

M3YY30; M3YY30_MUSPF

Genbank Protein ID

ENSMPUP00000016240

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01044785

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000016343.1	ENSMPUT00000016484.1	ENSMPUP00000016240.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	90.14	0.00e+00	1954.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	28.90	1.00e-42	170.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MRRFKRKHLT AIDCQHLARS HLAVTQPFCQ RWTNRDPNHG LYPRPRTKRG TRGQGCQGYN 60
TEFFPAARQR CINDMAKSSS VGQDTSKDSE GDMIFAAENH CALPQEEDGE ARLGVAGSAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTAAGTAAT TAAGATATAT TACTTTTTTT TTTTTTTTAA AGACGTTCCC GGGAATACAG 60
ACGTGGCTGT GAGATTGGAT TGCTGACGCA TTTCATGTCT TCCCATTAGG TGGCATCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

SMART

SM00256--FBOX

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	45.65	8.00e-04	40.00
IUUC-Aml-001396	Ailuropoda melanoleuca	93.78	0.00e+00	1993.00
IUUC-Atr-002826	Amborella trichopoda	40.00	6.00e-04	40.40
IUUC-Apl-003317	Anas platyrhynchos	48.13	0.00e+00	926.00
IUUC-Aca-004498	Anolis carolinensis	54.57	0.00e+00	941.00
IUUC-Ath-007293	Arabidopsis thaliana	37.68	4.00e-03	37.40
IUUC-Ago-007983	Ashbya gossypii	35.71	2.00e+00	28.50
IUUC-Ani-009226	Aspergillus nidulans	33.03	3.00e-05	44.70
IUUC-Ate-010526	Aspergillus terreus	39.71	9.00e-04	39.70
IUUC-Ame-011808	Astyanax mexicanus	57.89	2.00e-133	468.00
IUUC-Bta-013250	Bos taurus	88.91	0.00e+00	1884.00
IUUC-Bol-015348	Brassica oleracea	37.68	3.00e-03	37.70
IUUC-Cja-019638	Callithrix jacchus	90.43	0.00e+00	1955.00
IUUC-Cfa-020195	Canis familiaris	94.24	0.00e+00	1881.00
IUUC-Cpo-022269	Cavia porcellus	84.88	0.00e+00	1778.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	40.28	4.00e-08	53.90
IUUC-Csa-024060	Chlorocebus sabaeus	91.14	0.00e+00	1741.00
IUUC-Cho-025003	Choloepus hoffmanni	89.65	0.00e+00	709.00
IUUC-Cin-025694	Ciona intestinalis	26.24	1.00e-28	120.00
IUUC-Cne-026882	Cryptococcus neoformans	29.55	2.10e-01	32.00
IUUC-Dre-028083	Danio rerio	50.29	0.00e+00	851.00
IUUC-Dno-029203	Dasypus novemcinctus	86.91	0.00e+00	1764.00
IUUC-Dor-030477	Dipodomys ordii	97.19	0.00e+00	791.00
IUUC-Ete-032861	Echinops telfairi	87.19	0.00e+00	1833.00
IUUC-Eca-033205	Equus caballus	92.83	0.00e+00	2005.00
IUUC-Eeu-034784	Erinaceus europaeus	85.92	0.00e+00	1198.00
IUUC-Fca-035797	Felis catus	92.08	0.00e+00	1974.00
IUUC-Gmo-038855	Gadus morhua	46.27	3.00e-121	429.00
IUUC-Gga-040326	Gallus gallus	50.39	0.00e+00	964.00
IUUC-Gac-042240	Gasterosteus aculeatus	42.18	0.00e+00	729.00
IUUC-Ggo-045050	Gorilla gorilla	86.50	0.00e+00	1791.00
IUUC-Hsa-046650	Homo sapiens	89.47	0.00e+00	1886.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	96.90	0.00e+00	778.00
IUUC-Lch-050231	Latimeria chalumnae	42.21	2.00e-158	553.00
IUUC-Loc-051884	Lepisosteus oculatus	49.20	0.00e+00	969.00
IUUC-Lma-053267	Leptosphaeria maculans	25.45	3.00e-03	37.70
IUUC-Laf-053843	Loxodonta africana	89.20	0.00e+00	1890.00
IUUC-Mcc-055570	Macaca mulatta	90.43	0.00e+00	1913.00
IUUC-Meu-056798	Macropus eugenii	66.41	2.00e-147	516.00
IUUC-Mtr-057915	Medicago truncatula	36.76	6.00e-04	40.40
IUUC-Mga-059648	Meleagris gallopavo	50.97	0.00e+00	927.00
IUUC-Mmr-060757	Microcebus murinus	87.97	0.00e+00	1833.00
IUUC-Mdo-061913	Monodelphis domestica	68.52	0.00e+00	1357.00
IUUC-Mmu-064337	Mus musculus	88.05	0.00e+00	1898.00
IUUC-Mlu-068204	Myotis lucifugus	85.40	0.00e+00	1826.00
IUUC-Ncr-068735	Neurospora crassa	37.50	4.00e-03	37.40
IUUC-Nle-070053	Nomascus leucogenys	90.14	0.00e+00	1858.00
IUUC-Opr-070588	Ochotona princeps	84.42	0.00e+00	1765.00
IUUC-Ont-072655	Oreochromis niloticus	47.01	0.00e+00	748.00
IUUC-Oan-073351	Ornithorhynchus anatinus	62.29	0.00e+00	1289.00
IUUC-Ocu-074465	Oryctolagus cuniculus	88.84	0.00e+00	1819.00
IUUC-Oin-079176	Oryza indica	24.24	2.00e-05	44.30
IUUC-Olo-080505	Oryza longistaminata	30.77	2.00e-03	39.70
IUUC-Olu-087831	Ostreococcus lucimarinus	32.33	4.00e-65	243.00
IUUC-Oga-089088	Otolemur garnettii	87.27	0.00e+00	1815.00
IUUC-Oar-089870	Ovis aries	88.43	0.00e+00	1840.00
IUUC-Ptr-090957	Pan troglodytes	90.04	0.00e+00	1859.00
IUUC-Pan-092632	Papio anubis	90.24	0.00e+00	1860.00
IUUC-Psi-093035	Pelodiscus sinensis	54.61	0.00e+00	1119.00
IUUC-Pno-094870	Phaeosphaeria nodorum	24.20	4.00e-04	40.40
IUUC-Ppa-095660	Physcomitrella patens	38.36	5.00e-04	40.40
IUUC-Pfo-096902	Poecilia formosa	44.23	0.00e+00	674.00
IUUC-Pab-098206	Pongo abelii	90.09	0.00e+00	1755.00
IUUC-Pop-098801	Populus trichocarpa	34.72	6.00e-04	40.00
IUUC-Pca-100238	Procavia capensis	83.75	0.00e+00	1758.00
IUUC-Ppe-101748	Prunus persica	35.94	8.00e-03	36.60
IUUC-Pva-103182	Pteropus vampyrus	90.25	0.00e+00	1861.00
IUUC-Pte-104033	Pyrenophora teres	23.92	1.00e-03	39.30
IUUC-Pyt-104599	Pyrenophora triticirepentis	23.57	6.00e-04	39.70
IUUC-Rno-105141	Rattus norvegicus	88.15	0.00e+00	1900.00
IUUC-Sce-106341	Saccharomyces cerevisiae	25.76	2.00e-03	37.40
IUUC-Sha-106827	Sarcophilus harrisii	66.73	0.00e+00	1418.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	28.21	2.00e-40	160.00
IUUC-Spo-108147	Schizosaccharomyces pombe	28.90	1.00e-42	168.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	23.86	2.00e-03	38.10
IUUC-Sly-111170	Solanum lycopersicum	33.33	5.50e-02	32.70
IUUC-Sre-115025	Sporisorium reilianum	33.55	4.00e-38	154.00
IUUC-Ssc-116188	Sus scrofa	95.07	0.00e+00	1267.00
IUUC-Tgu-116612	Taeniopygia guttata	56.76	2.00e-156	545.00
IUUC-Tsy-119560	Tarsius syrichta	84.21	1.00e-117	417.00
IUUC-Tni-120734	Tetraodon nigroviridis	45.59	0.00e+00	703.00
IUUC-Tca-121338	Theobroma cacao	31.51	1.50e-02	35.80
IUUC-Tre-122089	Trichoderma reesei	40.74	3.00e-04	40.80
IUUC-Tme-127009	Tuber melanosporum	30.77	3.00e-03	38.10
IUUC-Tbe-127431	Tupaia belangeri	88.89	0.00e+00	1623.00
IUUC-Ttr-128744	Tursiops truncatus	89.02	0.00e+00	1852.00
IUUC-Uma-129536	Ustilago maydis	34.06	9.00e-40	159.00
IUUC-Vpa-130123	Vicugna pacos	77.08	1.00e-106	380.00
IUUC-Vvi-131025	Vitis vinifera	37.50	3.00e-03	37.70
IUUC-Xtr-132902	Xenopus tropicalis	52.22	0.00e+00	1028.00
IUUC-Xma-133978	Xiphophorus maculatus	46.00	3.00e-150	525.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence