iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093035

Ensembl Protein ID

ENSPSIP00000015662.1

UniProt Accession

K7G5V1; K7G5V1_PELSI

Genbank Protein ID

ENSPSIP00000015662

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01066768

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000013802.1	ENSPSIT00000015736.1	ENSPSIP00000015662.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	55.92	0.00e+00	1158.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	28.07	8.00e-39	157.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

KPFKQKRLTA SDCEAFRQSR EGSCSLTQPF SQRRVSRDLN RGLYPTYRTK RSQEGQGHQR 60
SITDYFKVTQ TQSTGNNTAI SNEVKEESLD SFFMDDFLED HCAPLECEGD TNPAPWDPAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAGAGGGGT ATTACGCATT GGGGACAGGG ATCAGGTTCT GCTTTGGGGC CAGGGGTAGG 60
ATCTGGGGTG GGTTTGCATT GGGGGCCAGG AATAGGCATG GGCAGGTAAA GGCAGTTAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

SMART

SM00256--FBOX

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	43.48	2.00e-03	38.50
IUUC-Aml-001396	Ailuropoda melanoleuca	55.27	0.00e+00	1107.00
IUUC-Atr-002826	Amborella trichopoda	31.71	4.00e-04	40.80
IUUC-Apl-003317	Anas platyrhynchos	57.02	0.00e+00	1118.00
IUUC-Aca-004498	Anolis carolinensis	55.48	0.00e+00	1044.00
IUUC-Aly-006174	Arabidopsis lyrata	32.10	1.00e-05	41.60
IUUC-Ath-007293	Arabidopsis thaliana	37.68	2.00e-03	38.50
IUUC-Acl-008341	Aspergillus clavatus	42.86	4.60e-02	33.50
IUUC-Ani-009226	Aspergillus nidulans	34.25	8.00e-03	36.20
IUUC-Ate-010526	Aspergillus terreus	45.45	2.00e-03	38.10
IUUC-Ame-011808	Astyanax mexicanus	56.15	4.00e-117	414.00
IUUC-Bta-013250	Bos taurus	54.72	0.00e+00	1096.00
IUUC-Bol-015348	Brassica oleracea	37.68	2.00e-03	38.10
IUUC-Cja-019638	Callithrix jacchus	55.58	0.00e+00	1154.00
IUUC-Cfa-020195	Canis familiaris	56.57	0.00e+00	1090.00
IUUC-Cpo-022269	Cavia porcellus	52.82	0.00e+00	1056.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	29.33	3.00e-10	60.80
IUUC-Csa-024060	Chlorocebus sabaeus	57.97	0.00e+00	1054.00
IUUC-Cho-025003	Choloepus hoffmanni	56.97	4.00e-131	462.00
IUUC-Cin-025694	Ciona intestinalis	29.08	5.00e-32	131.00
IUUC-Dre-028083	Danio rerio	48.03	0.00e+00	806.00
IUUC-Dno-029203	Dasypus novemcinctus	53.59	0.00e+00	1023.00
IUUC-Dor-030477	Dipodomys ordii	67.44	2.00e-155	543.00
IUUC-Ete-032861	Echinops telfairi	55.71	0.00e+00	1104.00
IUUC-Eca-033205	Equus caballus	55.30	0.00e+00	1141.00
IUUC-Eeu-034784	Erinaceus europaeus	58.16	0.00e+00	813.00
IUUC-Fca-035797	Felis catus	55.08	0.00e+00	1118.00
IUUC-Fso-038397	Fusarium solani	42.86	9.70e-02	32.30
IUUC-Gmo-038855	Gadus morhua	43.42	1.00e-117	417.00
IUUC-Gga-040326	Gallus gallus	59.69	0.00e+00	1186.00
IUUC-Gac-042240	Gasterosteus aculeatus	45.27	0.00e+00	682.00
IUUC-Ggo-045050	Gorilla gorilla	52.61	0.00e+00	1041.00
IUUC-Hsa-046650	Homo sapiens	55.49	0.00e+00	1127.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	62.89	8.00e-147	513.00
IUUC-Lch-050231	Latimeria chalumnae	41.75	8.00e-150	524.00
IUUC-Loc-051884	Lepisosteus oculatus	48.45	0.00e+00	961.00
IUUC-Lma-052982	Leptosphaeria maculans	28.36	3.00e-03	37.40
IUUC-Laf-053843	Loxodonta africana	54.92	0.00e+00	1111.00
IUUC-Mcc-055570	Macaca mulatta	55.46	0.00e+00	1140.00
IUUC-Meu-056798	Macropus eugenii	47.42	2.00e-102	367.00
IUUC-Mtr-057915	Medicago truncatula	35.71	5.00e-04	40.40
IUUC-Mga-059648	Meleagris gallopavo	61.08	0.00e+00	1136.00
IUUC-Mmr-060757	Microcebus murinus	54.78	0.00e+00	1085.00
IUUC-Mdo-061913	Monodelphis domestica	53.77	0.00e+00	1013.00
IUUC-Mmu-064337	Mus musculus	54.95	0.00e+00	1131.00
IUUC-Mac-064479	Musa acuminata	34.94	6.00e-04	39.70
IUUC-Mpu-066483	Mustela putorius furo	54.61	0.00e+00	1132.00
IUUC-Mlu-068204	Myotis lucifugus	52.81	0.00e+00	1060.00
IUUC-Ncr-068735	Neurospora crassa	23.08	8.00e-03	36.20
IUUC-Nle-070053	Nomascus leucogenys	54.75	0.00e+00	1103.00
IUUC-Opr-070588	Ochotona princeps	51.78	0.00e+00	1027.00
IUUC-Ont-072655	Oreochromis niloticus	44.52	0.00e+00	702.00
IUUC-Oan-073351	Ornithorhynchus anatinus	53.54	0.00e+00	1084.00
IUUC-Ocu-074465	Oryctolagus cuniculus	54.55	0.00e+00	1066.00
IUUC-Oba-075931	Oryza barthii	48.78	3.00e-04	38.50
IUUC-Obr-076710	Oryza brachyantha	23.78	9.00e-03	36.20
IUUC-Ogl-077337	Oryza glaberrima	48.78	2.00e-04	39.30
IUUC-Ogu-078861	Oryza glumaepatula	47.50	7.00e-04	38.10
IUUC-Oin-079568	Oryza indica	37.14	1.00e-04	39.30
IUUC-Ome-081984	Oryza meridionalis	40.00	9.00e-03	35.40
IUUC-Oni-082468	Oryza nivara	40.00	9.00e-03	35.40
IUUC-Opu-083652	Oryza punctata	30.59	6.00e-04	38.90
IUUC-Oru-084992	Oryza rufipogon	47.50	6.00e-04	38.50
IUUC-Olu-087831	Ostreococcus lucimarinus	32.63	4.00e-67	250.00
IUUC-Oga-089088	Otolemur garnettii	55.01	0.00e+00	1090.00
IUUC-Oar-089870	Ovis aries	54.43	0.00e+00	1082.00
IUUC-Ptr-090957	Pan troglodytes	55.73	0.00e+00	1112.00
IUUC-Pan-092632	Papio anubis	54.60	0.00e+00	1098.00
IUUC-Pno-094870	Phaeosphaeria nodorum	33.33	1.00e-03	39.30
IUUC-Ppa-095563	Physcomitrella patens	43.59	2.00e-04	40.00
IUUC-Pfo-096902	Poecilia formosa	43.48	0.00e+00	652.00
IUUC-Pab-098206	Pongo abelii	54.62	0.00e+00	1044.00
IUUC-Pca-100238	Procavia capensis	52.58	0.00e+00	1053.00
IUUC-Pva-103182	Pteropus vampyrus	55.15	0.00e+00	1111.00
IUUC-Pte-104033	Pyrenophora teres	23.02	1.00e-03	38.90
IUUC-Pyt-104599	Pyrenophora triticirepentis	23.40	1.00e-03	38.90
IUUC-Rno-105141	Rattus norvegicus	55.38	0.00e+00	1140.00
IUUC-Sce-106341	Saccharomyces cerevisiae	27.59	2.00e-04	40.80
IUUC-Sha-106827	Sarcophilus harrisii	51.90	0.00e+00	1056.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	25.82	1.00e-40	161.00
IUUC-Spo-108147	Schizosaccharomyces pombe	28.07	2.00e-39	157.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	26.15	3.00e-04	40.80
IUUC-Sly-111170	Solanum lycopersicum	32.67	4.50e-02	32.70
IUUC-Sre-115025	Sporisorium reilianum	31.68	2.00e-37	150.00
IUUC-Ssc-116188	Sus scrofa	61.33	0.00e+00	833.00
IUUC-Tgu-116612	Taeniopygia guttata	64.23	0.00e+00	651.00
IUUC-Tsy-119560	Tarsius syrichta	53.23	1.00e-69	258.00
IUUC-Tni-120734	Tetraodon nigroviridis	43.95	0.00e+00	651.00
IUUC-Tre-122089	Trichoderma reesei	30.00	6.00e-04	39.70
IUUC-Tae-125683	Triticum aestivum	35.71	7.00e-05	42.40
IUUC-Tme-127009	Tuber melanosporum	28.57	1.00e-03	38.90
IUUC-Tbe-127431	Tupaia belangeri	54.49	0.00e+00	929.00
IUUC-Ttr-128744	Tursiops truncatus	52.67	0.00e+00	1056.00
IUUC-Uma-129536	Ustilago maydis	33.44	1.00e-39	158.00
IUUC-Vpa-130123	Vicugna pacos	85.14	1.00e-34	141.00
IUUC-Xtr-132902	Xenopus tropicalis	54.65	0.00e+00	955.00
IUUC-Xma-133978	Xiphophorus maculatus	43.64	7.00e-142	497.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence