iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115586

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU463216

Gene Name

USP21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000006362.2	ENSSSCT00000006971.2	ENSSSCP00000006781.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.00e-91	306.0	212	556

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +Gl+NlgNtC++N+vLQcLs++++lr+++l+  ++++++     ++ +el++++++++ +lw  ++ +av+p+++ ++++k+ ++fsgy
   Q: 212  VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRrDFRQEVPG---GGRAQELTEAFADVIGALWhPDSCEAVNPTRFRAVFQKYVPSFSGY 297
           6******************************667777776...5789***************888899********************* PP
   S: 88   eqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikcle 158
           +qqDaqEfl+ l+++l+ e+++                  ++     ee e ++ ++ +  +++  ++++s i+dlF gqlks +kc++
   Q: 298  SQQDAQEFLKLLMERLHLEINRrgrrappilasspapsppRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQA 386
           ********************9988788888777776666655555556666666666666***************************** PP
   S: 159  cdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksr 246
           c+ +s+++e f+dlslp+p+k     k sl+dc++ ftkeeele+en+  c++c++k++++kkl+++++P++L+lhL+Rf  s +++s 
   Q: 387  CGYRSTTFEVFCDLSLPIPKKGFAgGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRF--SASRGSI 473
           *******************887541456****************************************************..5566899 PP
   S: 247  ekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlf 334
           +k +  v+fpl+ L+l  f +++      + +Y+L+a ++HsGs++ GHY+a+++  + +W  ++Ds+V++v+e++v +   s++Yvlf
   Q: 474  KKSSVGVDFPLQrLSLGDFASDKAG----SPIYQLYALCNHSGSVHYGHYTALCRC-QTGWHVYNDSRVSPVSENQVAS---SEGYVLF 554
           9**********99*******99543....78*************************.777*******************...******* PP
   S: 335  Yk 336
           Y+
   Q: 555  YQ 556
           *8 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MPQASEHRLG RTREPPLNVQ PRVGSKLPFA PRARSKERRN PAPGPNPMLR PLPPRPGPPE 60
ERLKKLELGR GRTSGPRPRG PLRADHGVPL PGSPPPTVAL PLPSRTNLAR SKSVSSGDLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCAGCCTG TGGTGTCCAC AATGCCCCAG GCTTCTGAGC ACCGCCTGGG ACGGACCCGA 60
GAGCCACCTC TTAATGTCCA GCCCCGAGTG GGATCCAAGC TACCATTTGC TCCCAGGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ssc:100152455

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	98.23	0.00e+00	1016.00
IUUC-Aca-004612	Anolis carolinensis	59.50	3.00e-175	608.00
IUUC-Ame-011548	Astyanax mexicanus	51.98	6.00e-104	370.00
IUUC-Bta-012626	Bos taurus	98.41	0.00e+00	988.00
IUUC-Cja-018853	Callithrix jacchus	97.52	0.00e+00	1023.00
IUUC-Cfa-021167	Canis familiaris	98.76	0.00e+00	1000.00
IUUC-Cpo-021305	Cavia porcellus	96.47	0.00e+00	950.00
IUUC-Csa-023454	Chlorocebus sabaeus	97.70	0.00e+00	1026.00
IUUC-Cho-024836	Choloepus hoffmanni	96.89	1.00e-108	386.00
IUUC-Dre-028454	Danio rerio	53.52	4.00e-108	384.00
IUUC-Dno-029955	Dasypus novemcinctus	92.97	0.00e+00	643.00
IUUC-Dor-031053	Dipodomys ordii	97.17	0.00e+00	1047.00
IUUC-Ete-032416	Echinops telfairi	95.88	6.00e-145	507.00
IUUC-Eca-033817	Equus caballus	97.88	0.00e+00	1016.00
IUUC-Fca-036400	Felis catus	97.53	0.00e+00	989.00
IUUC-Gmo-038926	Gadus morhua	54.24	2.00e-104	372.00
IUUC-Gac-041331	Gasterosteus aculeatus	53.31	8.00e-108	383.00
IUUC-Ggo-045174	Gorilla gorilla	97.70	0.00e+00	1026.00
IUUC-Hsa-046443	Homo sapiens	97.52	0.00e+00	1027.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	97.01	0.00e+00	1008.00
IUUC-Lch-050539	Latimeria chalumnae	61.67	1.00e-105	376.00
IUUC-Loc-051808	Lepisosteus oculatus	56.35	9.00e-117	413.00
IUUC-Laf-053730	Loxodonta africana	96.13	0.00e+00	1018.00
IUUC-Mcc-055541	Macaca mulatta	97.70	0.00e+00	1026.00
IUUC-Meu-056279	Macropus eugenii	91.17	0.00e+00	966.00
IUUC-Mmr-060913	Microcebus murinus	97.88	0.00e+00	952.00
IUUC-Mdo-061807	Monodelphis domestica	91.17	0.00e+00	893.00
IUUC-Mmu-063599	Mus musculus	96.13	0.00e+00	967.00
IUUC-Mpu-066329	Mustela putorius furo	99.12	0.00e+00	1002.00
IUUC-Mlu-067359	Myotis lucifugus	95.04	0.00e+00	890.00
IUUC-Nle-068975	Nomascus leucogenys	95.40	0.00e+00	995.00
IUUC-Opr-071096	Ochotona princeps	94.69	0.00e+00	957.00
IUUC-Ocu-074228	Oryctolagus cuniculus	97.18	0.00e+00	985.00
IUUC-Ola-086684	Oryzias latipes	50.42	1.00e-101	362.00
IUUC-Oga-088007	Otolemur garnettii	79.33	0.00e+00	772.00
IUUC-Oar-090226	Ovis aries	98.19	0.00e+00	774.00
IUUC-Ptr-091522	Pan troglodytes	97.70	0.00e+00	1026.00
IUUC-Pan-091954	Papio anubis	97.35	0.00e+00	1019.00
IUUC-Psi-093216	Pelodiscus sinensis	60.16	0.00e+00	676.00
IUUC-Pfo-096257	Poecilia formosa	50.14	7.00e-102	363.00
IUUC-Pab-098691	Pongo abelii	97.52	0.00e+00	1025.00
IUUC-Pca-101133	Procavia capensis	89.73	0.00e+00	957.00
IUUC-Pva-102681	Pteropus vampyrus	94.87	0.00e+00	945.00
IUUC-Rno-105132	Rattus norvegicus	96.81	0.00e+00	996.00
IUUC-Sha-107145	Sarcophilus harrisii	90.88	0.00e+00	879.00
IUUC-Tgu-117491	Taeniopygia guttata	81.48	4.00e-114	403.00
IUUC-Tni-120746	Tetraodon nigroviridis	51.64	1.00e-95	342.00
IUUC-Tbe-127465	Tupaia belangeri	99.07	7.00e-127	447.00
IUUC-Ttr-128274	Tursiops truncatus	96.28	0.00e+00	965.00
IUUC-Xtr-131989	Xenopus tropicalis	48.63	2.00e-125	442.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence