iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033433

Ensembl Protein ID

ENSECAP00000008793.1

UniProt Accession

F7DB95; F7DB95_HORSE

Protein Name

Uncharacterized protein

Gene Name

DNMBP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000010813.1	ENSECAT00000011272.1	ENSECAP00000008793.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.60e-48	160.2	248	298

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +++y ++a + +eL +  Gd+++++  ++ + gWl+g   l+g+ G+fP  Fv+
   Q: 248  GIAIYRFQALEPNELDFDVGDKIRIL--ATLEDGWLEG--SLKGRTGVFPYRFVK 298
           689***********************..999*******..9*************8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MEAGSVVRAV FDFCPSVSEE LPLFVGDIIE VLAVVDEFWL LGKKEDVTGQ FPSSFVEIVT 60
IPSLKEGERL FVCICEFTSQ ELNSLPLHRG DLVILDGALT GGWLQGRSCW GARGFFPSSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCTGTAGA GCATGGAGGC TGGCTCGGTG GTCCGAGCCG TCTTTGACTT CTGCCCGAGC 60
GTATCAGAAG AGCTGCCGCT CTTTGTGGGA GACATTATTG AAGTGTTGGC GGTGGTGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS00741--DH_1
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043547--P:positive regulation of GTPase activity
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

KEGG

ecb:100060622

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002128	Ailuropoda melanoleuca	84.38	0.00e+00	2373.00
IUUC-Apl-003934	Anas platyrhynchos	70.76	0.00e+00	1161.00
IUUC-Aca-005005	Anolis carolinensis	58.05	0.00e+00	1604.00
IUUC-Ame-011361	Astyanax mexicanus	58.23	0.00e+00	959.00
IUUC-Bta-013210	Bos taurus	85.28	0.00e+00	2426.00
IUUC-Bol-015745	Brassica oleracea	23.58	6.60e-01	28.50
IUUC-Cel-018396	Caenorhabditis elegans	26.09	3.00e-29	124.00
IUUC-Cja-019104	Callithrix jacchus	82.29	0.00e+00	2324.00
IUUC-Cfa-020960	Canis familiaris	84.03	0.00e+00	2386.00
IUUC-Cpo-022440	Cavia porcellus	79.47	0.00e+00	2283.00
IUUC-Csa-023391	Chlorocebus sabaeus	84.83	0.00e+00	2423.00
IUUC-Cho-024795	Choloepus hoffmanni	74.00	0.00e+00	1942.00
IUUC-Cin-025137	Ciona intestinalis	32.99	3.00e-30	124.00
IUUC-Dre-027932	Danio rerio	65.84	0.00e+00	860.00
IUUC-Dno-029750	Dasypus novemcinctus	83.11	0.00e+00	2423.00
IUUC-Dor-031109	Dipodomys ordii	75.37	0.00e+00	2046.00
IUUC-Ete-032660	Echinops telfairi	75.35	0.00e+00	1775.00
IUUC-Eeu-034929	Erinaceus europaeus	77.89	0.00e+00	1393.00
IUUC-Fca-035859	Felis catus	86.01	0.00e+00	2454.00
IUUC-Fal-036653	Ficedula albicollis	62.67	0.00e+00	1208.00
IUUC-Gmo-038948	Gadus morhua	59.81	0.00e+00	769.00
IUUC-Gga-040279	Gallus gallus	59.80	0.00e+00	1593.00
IUUC-Gac-041641	Gasterosteus aculeatus	56.42	0.00e+00	933.00
IUUC-Ggo-044900	Gorilla gorilla	30.38	3.00e-69	256.00
IUUC-Hsa-046063	Homo sapiens	84.70	0.00e+00	2407.00
IUUC-Itr-049071	Ictidomys tridecemlineatus	81.36	0.00e+00	2384.00
IUUC-Lch-049865	Latimeria chalumnae	49.16	0.00e+00	1148.00
IUUC-Lpe-050758	Leersia perrieri	52.17	2.40e-01	30.40
IUUC-Loc-051754	Lepisosteus oculatus	61.20	0.00e+00	1073.00
IUUC-Laf-054037	Loxodonta africana	81.46	0.00e+00	2417.00
IUUC-Mcc-055002	Macaca mulatta	84.83	0.00e+00	2426.00
IUUC-Meu-056420	Macropus eugenii	63.06	0.00e+00	1357.00
IUUC-Mga-059868	Meleagris gallopavo	71.49	0.00e+00	1138.00
IUUC-Mmr-060767	Microcebus murinus	83.88	0.00e+00	2428.00
IUUC-Mdo-061939	Monodelphis domestica	69.09	0.00e+00	1917.00
IUUC-Mmu-063980	Mus musculus	74.28	0.00e+00	2103.00
IUUC-Mpu-065913	Mustela putorius furo	83.55	0.00e+00	2451.00
IUUC-Mlu-067340	Myotis lucifugus	85.86	0.00e+00	2382.00
IUUC-Nle-069343	Nomascus leucogenys	84.51	0.00e+00	2367.00
IUUC-Opr-070694	Ochotona princeps	76.09	0.00e+00	2163.00
IUUC-Ont-071844	Oreochromis niloticus	59.19	0.00e+00	915.00
IUUC-Oan-073605	Ornithorhynchus anatinus	39.47	7.00e-61	228.00
IUUC-Ocu-074406	Oryctolagus cuniculus	80.61	0.00e+00	2279.00
IUUC-Opu-083196	Oryza punctata	47.83	1.00e+00	28.10
IUUC-Osa-085464	Oryza sativa	47.83	9.40e-01	28.10
IUUC-Ola-087343	Oryzias latipes	59.46	0.00e+00	686.00
IUUC-Oga-088847	Otolemur garnettii	82.54	0.00e+00	2362.00
IUUC-Oar-089817	Ovis aries	83.99	0.00e+00	2395.00
IUUC-Ptr-090508	Pan troglodytes	30.38	1.00e-69	257.00
IUUC-Pan-092104	Papio anubis	84.70	0.00e+00	2421.00
IUUC-Psi-094045	Pelodiscus sinensis	62.42	4.00e-92	332.00
IUUC-Pma-094663	Petromyzon marinus	38.88	9.00e-153	535.00
IUUC-Pfo-096714	Poecilia formosa	54.36	0.00e+00	929.00
IUUC-Pab-097918	Pongo abelii	84.70	0.00e+00	2400.00
IUUC-Pca-101096	Procavia capensis	77.34	0.00e+00	1274.00
IUUC-Pva-102490	Pteropus vampyrus	84.12	0.00e+00	2403.00
IUUC-Rno-105908	Rattus norvegicus	74.35	0.00e+00	2072.00
IUUC-Sha-107509	Sarcophilus harrisii	67.66	0.00e+00	1772.00
IUUC-Sbi-114441	Sorghum bicolor	41.67	9.10e-01	28.10
IUUC-Ssc-115250	Sus scrofa	83.96	0.00e+00	2300.00
IUUC-Tru-118279	Takifugu rubripes	56.82	0.00e+00	974.00
IUUC-Tni-120459	Tetraodon nigroviridis	63.41	0.00e+00	748.00
IUUC-Tbe-127753	Tupaia belangeri	68.40	0.00e+00	1009.00
IUUC-Ttr-129096	Tursiops truncatus	84.30	0.00e+00	1790.00
IUUC-Vpa-130643	Vicugna pacos	82.38	0.00e+00	1999.00
IUUC-Xtr-131979	Xenopus tropicalis	54.58	0.00e+00	1545.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence