iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097957

Ensembl Protein ID

ENSPPYP00000023607.1

UniProt Accession

K7ESU0; K7ESU0_PONAB

Genbank Protein ID

ENSPPYP00000023607

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01023186

Gene Name

KLHL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000029418.1	ENSPPYT00000032876.1	ENSPPYP00000023607.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.40e-19	70.3	6	69
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.40e-11	42.2	105	135

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dvil+v+ +ef++h++vLaa+S +F+a+f ++l+e+  ++++ ik+v++e + +ll++ Yt+k+
   Q: 6    TDVILCVDIQEFSCHRVVLAAASNYFRAMFCNDLKEKY-EKRIIIKGVDAETMHTLLDYTYTSKA 69
           7***********************************97.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           +eNc+gilr+Ad+++++ Lk++++++i+++F
   Q: 105  PENCVGILRLADTHSLDSLKKQVQSYIIQNF 135
           89***************************** PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MENALTDVIL CVDIQEFSCH RVVLAAASNY FRAMFCNDLK EKYEKRIIIK GVDAETMHTL 60
LDYTYTSKAL ITKQNVQRVL EAANLFQFLR MVDACASFLT EALNPENCVG ILRLADTHSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCGAATGGA AAATGCTCTG ACAGATGTCA TCTTGTGTGT GGACATTCAG GAATTCTCCT 60
GCCACCGCGT GGTGCTTGCC GCAGCCAGCA ACTATTTCAG GTCAGCATGC CTAGGACCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR029851--KLHL6
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0050853--P:B cell receptor signaling pathway
GO:0002467--P:germinal center formation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001509	Ailuropoda melanoleuca	98.25	0.00e+00	939.00
IUUC-Apl-003490	Anas platyrhynchos	87.06	0.00e+00	846.00
IUUC-Aca-005136	Anolis carolinensis	84.65	0.00e+00	827.00
IUUC-Ame-010886	Astyanax mexicanus	69.47	0.00e+00	662.00
IUUC-Bta-013473	Bos taurus	97.37	0.00e+00	906.00
IUUC-Bra-016823	Brassica rapa	32.88	4.00e-13	68.60
IUUC-Cja-018888	Callithrix jacchus	98.90	0.00e+00	946.00
IUUC-Cpo-021761	Cavia porcellus	86.68	0.00e+00	822.00
IUUC-Csa-023206	Chlorocebus sabaeus	100.00	0.00e+00	952.00
IUUC-Csv-026076	Ciona savignyi	42.16	1.00e-106	380.00
IUUC-Dre-027948	Danio rerio	73.46	0.00e+00	718.00
IUUC-Dno-030045	Dasypus novemcinctus	97.37	0.00e+00	932.00
IUUC-Dor-030839	Dipodomys ordii	88.16	0.00e+00	813.00
IUUC-Ete-033161	Echinops telfairi	95.78	3.00e-133	469.00
IUUC-Eca-033608	Equus caballus	97.15	0.00e+00	902.00
IUUC-Eeu-034640	Erinaceus europaeus	95.83	0.00e+00	923.00
IUUC-Fca-036065	Felis catus	97.15	0.00e+00	932.00
IUUC-Fal-036949	Ficedula albicollis	87.06	0.00e+00	849.00
IUUC-Gmo-039661	Gadus morhua	61.50	1.00e-168	586.00
IUUC-Gga-040740	Gallus gallus	86.18	0.00e+00	840.00
IUUC-Gac-042413	Gasterosteus aculeatus	63.13	7.00e-175	607.00
IUUC-Ggo-045167	Gorilla gorilla	100.00	0.00e+00	952.00
IUUC-Hsa-046120	Homo sapiens	100.00	0.00e+00	952.00
IUUC-Itr-047926	Ictidomys tridecemlineatus	98.03	0.00e+00	935.00
IUUC-Lch-049709	Latimeria chalumnae	81.36	0.00e+00	805.00
IUUC-Loc-052239	Lepisosteus oculatus	79.82	0.00e+00	783.00
IUUC-Laf-054511	Loxodonta africana	96.93	0.00e+00	932.00
IUUC-Mcc-055109	Macaca mulatta	100.00	0.00e+00	952.00
IUUC-Mga-060012	Meleagris gallopavo	84.65	0.00e+00	815.00
IUUC-Mmr-061364	Microcebus murinus	98.02	0.00e+00	935.00
IUUC-Mdo-063033	Monodelphis domestica	82.68	0.00e+00	749.00
IUUC-Mmu-063880	Mus musculus	95.82	0.00e+00	884.00
IUUC-Mlu-068233	Myotis lucifugus	97.59	0.00e+00	934.00
IUUC-Opr-070638	Ochotona princeps	97.92	0.00e+00	786.00
IUUC-Ont-071960	Oreochromis niloticus	63.72	1.00e-177	615.00
IUUC-Oan-073406	Ornithorhynchus anatinus	83.11	0.00e+00	801.00
IUUC-Ocu-074612	Oryctolagus cuniculus	98.03	0.00e+00	936.00
IUUC-Ola-087181	Oryzias latipes	61.76	1.00e-175	609.00
IUUC-Oga-088955	Otolemur garnettii	97.36	0.00e+00	929.00
IUUC-Oar-089682	Ovis aries	97.37	0.00e+00	906.00
IUUC-Ptr-090969	Pan troglodytes	100.00	0.00e+00	952.00
IUUC-Pan-092289	Papio anubis	100.00	0.00e+00	952.00
IUUC-Psi-093279	Pelodiscus sinensis	87.50	0.00e+00	848.00
IUUC-Pca-100619	Procavia capensis	94.52	0.00e+00	915.00
IUUC-Pva-102533	Pteropus vampyrus	97.47	0.00e+00	632.00
IUUC-Rno-106111	Rattus norvegicus	96.26	0.00e+00	917.00
IUUC-Sha-106716	Sarcophilus harrisii	83.33	0.00e+00	798.00
IUUC-Tgu-116839	Taeniopygia guttata	87.28	0.00e+00	847.00
IUUC-Tru-117792	Takifugu rubripes	63.05	5.00e-173	600.00
IUUC-Tsy-119609	Tarsius syrichta	92.41	5.00e-129	454.00
IUUC-Tni-119682	Tetraodon nigroviridis	63.27	2.00e-174	605.00
IUUC-Tbe-127961	Tupaia belangeri	89.91	0.00e+00	816.00
IUUC-Ttr-128917	Tursiops truncatus	96.48	0.00e+00	926.00
IUUC-Vpa-130721	Vicugna pacos	97.64	0.00e+00	864.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence