iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060019

UUCD1 version

UUC-MeG-00838

Ensembl Protein ID

ENSMGAP00000009884.2

UniProt Accession

G1NBA2; G1NBA2_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP33

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000009520.2	ENSMGAT00000010725.2	ENSMGAP00000009884.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.40e-112	374.3	3	533

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tGlkN+gNtCYmN++LQ+Lsn+p+l++++l+     +   +++++k +++ks+ kl++elw k++ ++v p+ l++ +k++++ f+gy+
   Q: 3    TGLKNIGNTCYMNAALQALSNCPPLTHFFLD-----CGGLARTDKKPAICKSYLKLMTELWhKNRPGSVVPTGLFQGIKSVNPTFRGYS 86
           7******************************.....999999*******************9999************************ PP
   S: 89   qqDaqEflaflldqleeelkk.......eknkpkeeeeeedkselsde......................................... 129
           qqDaqEfl++l+d l+eelk+        + +++ee++e dk     +                                         
   Q: 87   QQDAQEFLRCLMDLLHEELKEpivevedAQATSVEESMEVDK-----Sqsdaglqpcescgtcdkiendavfkpaledpaettmliqdd 170
           *******************88776655444444444444444.....144456************************************ PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 171  ennsiiskdwqkekissnklnransmedlekntnstseaneflnnqgtvkvqihsrfseyindvhmndvsgaqtlssnegmntrlsssp 259
           ***************************************************************************************** PP
   S: 130  ......................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke........... 185
                                  ++kk kk++s+isd+F+g++ s+++cl+cd+ s++ e+f+dlslp+pgke+ +k+           
   Q: 260  pksctscsastpihkkvstvssPKRKKCKKYRSVISDIFDGTIVSSVQCLTCDRLSVTLETFQDLSLPIPGKEDLAKLhsashqtslvk 348
           ********************99889999*********************************************99888*********** PP
   S: 186  ......................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkR 236
                                                 +lqdcL++f++++el+g+n+y+c +ckk+++ +k +k++k+Pe+L++hLkR
   Q: 349  tgscgeayapqgwiaffmeyfkrfvvscvpswfwgpvvTLQDCLAAFFARDELKGDNMYSCGRCKKLRNGVKFCKVQKFPEILCIHLKR 437
           ***************************************************************************************** PP
   S: 237  fsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevl 323
           f  ++e ++++ki ++v+fple Ldl+pf+++++ +q   ++Y+L++v++H+G++ssGHY+ay++n+ ++ W++fdD++Vtev+e++v+
   Q: 438  F--RHELMFSTKIGTHVSFPLEgLDLQPFLAKDSPAQ--IVTYDLLSVICHHGTASSGHYIAYCRNNLNNlWYEFDDQSVTEVSESTVQ 522
           *..9999*************************88777..9**************************88889****************** PP
   S: 324  eetgstaYvlfYkr 337
           +   ++aYvlfY +
   Q: 523  N---AEAYVLFYSN 533
           *...********86 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

GLTGLKNIGN TCYMNAALQA LSNCPPLTHF FLDCGGLART DKKPAICKSY LKLMTELWHK 60
NRPGSVVPTG LFQGIKSVNP TFRGYSQQDA QEFLRCLMDL LHEELKEPIV EVEDAQATSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCTAACAG GATTAAAAAA TATTGGTAAC ACTTGTTACA TGAATGCAGC TTTACAGGCT 60
CTTTCCAACT GGTAAGCAGA ATGGTTGTAA ATGAGATTTT CTATTTGCTT GTGCACATAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005776--C:autophagosome
GO:0044297--C:cell body
GO:0005813--C:centrosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0007411--P:axon guidance
GO:0016477--P:cell migration
GO:0009267--P:cellular response to starvation
GO:0051298--P:centrosome duplication
GO:0032091--P:negative regulation of protein binding
GO:0032092--P:positive regulation of protein binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050821--P:protein stabilization
GO:0010506--P:regulation of autophagy
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001742	Ailuropoda melanoleuca	82.44	0.00e+00	1290.00
IUUC-Apl-003987	Anas platyrhynchos	93.05	0.00e+00	1412.00
IUUC-Aca-004713	Anolis carolinensis	78.24	0.00e+00	1196.00
IUUC-Bta-013132	Bos taurus	82.75	0.00e+00	1292.00
IUUC-Cel-018627	Caenorhabditis elegans	33.60	5.00e-37	149.00
IUUC-Cja-018811	Callithrix jacchus	82.72	0.00e+00	1296.00
IUUC-Cfa-021158	Canis familiaris	82.70	0.00e+00	1291.00
IUUC-Cpo-021910	Cavia porcellus	74.67	0.00e+00	1117.00
IUUC-Csa-023130	Chlorocebus sabaeus	82.85	0.00e+00	1294.00
IUUC-Cho-024383	Choloepus hoffmanni	63.49	6.00e-94	338.00
IUUC-Csv-025889	Ciona savignyi	45.81	1.00e-36	145.00
IUUC-Dre-028639	Danio rerio	70.85	0.00e+00	1065.00
IUUC-Dno-029416	Dasypus novemcinctus	82.48	0.00e+00	1261.00
IUUC-Ete-032994	Echinops telfairi	74.42	4.00e-157	548.00
IUUC-Eca-034248	Equus caballus	82.88	0.00e+00	1295.00
IUUC-Eeu-035357	Erinaceus europaeus	67.80	0.00e+00	976.00
IUUC-Fca-036013	Felis catus	82.38	0.00e+00	1289.00
IUUC-Fal-037509	Ficedula albicollis	91.09	0.00e+00	1411.00
IUUC-Gga-040647	Gallus gallus	96.46	0.00e+00	1467.00
IUUC-Hsa-045694	Homo sapiens	82.20	0.00e+00	1286.00
IUUC-Itr-049041	Ictidomys tridecemlineatus	82.22	0.00e+00	1276.00
IUUC-Lch-050400	Latimeria chalumnae	70.64	0.00e+00	1083.00
IUUC-Loc-052616	Lepisosteus oculatus	71.50	0.00e+00	1116.00
IUUC-Laf-053493	Loxodonta africana	83.05	0.00e+00	1294.00
IUUC-Mcc-055542	Macaca mulatta	82.85	0.00e+00	1295.00
IUUC-Meu-056645	Macropus eugenii	72.60	0.00e+00	1053.00
IUUC-Mmr-061241	Microcebus murinus	79.45	0.00e+00	1224.00
IUUC-Mmu-063786	Mus musculus	79.71	0.00e+00	1236.00
IUUC-Mpu-065772	Mustela putorius furo	81.65	0.00e+00	1258.00
IUUC-Mlu-067732	Myotis lucifugus	81.92	0.00e+00	1287.00
IUUC-Nle-069528	Nomascus leucogenys	81.65	0.00e+00	1294.00
IUUC-Opr-070606	Ochotona princeps	79.32	0.00e+00	1131.00
IUUC-Ont-071495	Oreochromis niloticus	70.61	0.00e+00	1077.00
IUUC-Ocu-074457	Oryctolagus cuniculus	82.62	0.00e+00	1288.00
IUUC-Ola-086739	Oryzias latipes	69.68	0.00e+00	1098.00
IUUC-Oga-088720	Otolemur garnettii	81.72	0.00e+00	1291.00
IUUC-Oar-089921	Ovis aries	82.75	0.00e+00	1294.00
IUUC-Ptr-090526	Pan troglodytes	82.20	0.00e+00	1286.00
IUUC-Pan-092396	Papio anubis	83.18	0.00e+00	1290.00
IUUC-Psi-092971	Pelodiscus sinensis	84.69	0.00e+00	1318.00
IUUC-Pab-098740	Pongo abelii	82.44	0.00e+00	1310.00
IUUC-Pva-102820	Pteropus vampyrus	82.75	0.00e+00	1113.00
IUUC-Rno-104894	Rattus norvegicus	80.81	0.00e+00	1251.00
IUUC-Sha-107244	Sarcophilus harrisii	74.22	0.00e+00	1123.00
IUUC-Sar-113665	Sorex araneus	82.35	0.00e+00	1304.00
IUUC-Ssc-115793	Sus scrofa	80.03	0.00e+00	1219.00
IUUC-Tgu-117487	Taeniopygia guttata	92.78	0.00e+00	1366.00
IUUC-Tsy-119598	Tarsius syrichta	75.70	0.00e+00	1109.00
IUUC-Tbe-128125	Tupaia belangeri	82.56	2.00e-87	317.00
IUUC-Ttr-128269	Tursiops truncatus	82.59	0.00e+00	1249.00
IUUC-Vpa-130598	Vicugna pacos	80.68	0.00e+00	1251.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence