iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093681

Ensembl Protein ID

ENSPSIP00000015926.1

UniProt Accession

K7G6L5; K7G6L5_PELSI

Genbank Protein ID

ENSPSIP00000015926

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01164260

Gene Name

TRAF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000014213.1	ENSPSIT00000016001.1	ENSPSIP00000015926.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	73.53	0.00e+00	786.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MAAANLTPPG SLDLNLPGFS REILGTKLEG KYLCSECKNI LRRPFQAQCG HRYCSYCLKK 60
LISSGPQKCA ACIQEGIYEE GVSILETNSA FPDNAARREV ESLPSVCIND GCTWKGTIKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCTTGAGG TGCATCCGGG GTATTTGGTT CACATGGCAG CAGCAAACTT GACTCCACCT 60
GGTTCTTTGG ATTTAAATCT GCCTGGATTT TCGAGAGAGA TACTTGGGAC TAAATTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	73.88	0.00e+00	780.00
IUUC-Atr-002634	Amborella trichopoda	30.20	1.00e-07	52.80
IUUC-Apl-004202	Anas platyrhynchos	85.66	0.00e+00	902.00
IUUC-Aca-005029	Anolis carolinensis	55.91	3.00e-149	521.00
IUUC-Ame-011841	Astyanax mexicanus	52.97	6.00e-172	597.00
IUUC-Bta-013180	Bos taurus	72.78	0.00e+00	756.00
IUUC-Cja-019813	Callithrix jacchus	72.94	0.00e+00	782.00
IUUC-Cfa-021205	Canis familiaris	73.33	0.00e+00	770.00
IUUC-Cpo-021346	Cavia porcellus	71.96	0.00e+00	770.00
IUUC-Csa-023809	Chlorocebus sabaeus	73.88	0.00e+00	682.00
IUUC-Dre-027669	Danio rerio	58.27	4.00e-175	607.00
IUUC-Dno-029458	Dasypus novemcinctus	72.94	0.00e+00	769.00
IUUC-Dor-030338	Dipodomys ordii	68.82	0.00e+00	694.00
IUUC-Eca-034401	Equus caballus	74.51	0.00e+00	798.00
IUUC-Eeu-034668	Erinaceus europaeus	86.84	3.00e-78	285.00
IUUC-Fca-036057	Felis catus	73.93	0.00e+00	795.00
IUUC-Fal-037560	Ficedula albicollis	75.39	0.00e+00	741.00
IUUC-Gmo-038964	Gadus morhua	60.74	0.00e+00	647.00
IUUC-Gga-040425	Gallus gallus	85.88	0.00e+00	884.00
IUUC-Gac-041908	Gasterosteus aculeatus	61.99	0.00e+00	667.00
IUUC-Ggo-044606	Gorilla gorilla	66.47	0.00e+00	698.00
IUUC-Hsa-046952	Homo sapiens	73.53	0.00e+00	786.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	63.00	0.00e+00	642.00
IUUC-Lch-049571	Latimeria chalumnae	63.77	0.00e+00	728.00
IUUC-Loc-051973	Lepisosteus oculatus	62.15	1.00e-179	622.00
IUUC-Laf-053815	Loxodonta africana	71.76	0.00e+00	749.00
IUUC-Mcc-054888	Macaca mulatta	73.53	0.00e+00	781.00
IUUC-Meu-056547	Macropus eugenii	68.23	5.00e-177	613.00
IUUC-Mga-059819	Meleagris gallopavo	79.53	0.00e+00	827.00
IUUC-Mdo-062570	Monodelphis domestica	77.45	0.00e+00	823.00
IUUC-Mmu-063133	Mus musculus	69.02	0.00e+00	741.00
IUUC-Mpu-065802	Mustela putorius furo	73.18	0.00e+00	786.00
IUUC-Nle-070155	Nomascus leucogenys	73.73	0.00e+00	791.00
IUUC-Opr-070856	Ochotona princeps	63.53	2.00e-89	322.00
IUUC-Ont-071930	Oreochromis niloticus	63.92	0.00e+00	694.00
IUUC-Ola-087397	Oryzias latipes	62.69	0.00e+00	687.00
IUUC-Oga-088109	Otolemur garnettii	73.92	0.00e+00	791.00
IUUC-Oar-090310	Ovis aries	71.13	2.00e-106	379.00
IUUC-Ptr-090643	Pan troglodytes	73.73	0.00e+00	791.00
IUUC-Pan-091933	Papio anubis	73.53	0.00e+00	781.00
IUUC-Pfo-096148	Poecilia formosa	62.31	0.00e+00	685.00
IUUC-Pab-098631	Pongo abelii	73.73	0.00e+00	791.00
IUUC-Pca-100582	Procavia capensis	61.86	1.00e-68	253.00
IUUC-Pva-102396	Pteropus vampyrus	61.06	1.00e-177	615.00
IUUC-Rno-106120	Rattus norvegicus	68.43	0.00e+00	731.00
IUUC-Sha-106493	Sarcophilus harrisii	78.04	0.00e+00	835.00
IUUC-Sar-113570	Sorex araneus	85.37	1.00e-86	312.00
IUUC-Ssc-115843	Sus scrofa	71.96	0.00e+00	774.00
IUUC-Tgu-117144	Taeniopygia guttata	70.58	0.00e+00	710.00
IUUC-Tru-117853	Takifugu rubripes	62.21	0.00e+00	681.00
IUUC-Tni-120256	Tetraodon nigroviridis	63.92	0.00e+00	696.00
IUUC-Tbe-127943	Tupaia belangeri	53.07	1.00e-79	289.00
IUUC-Ttr-129246	Tursiops truncatus	72.16	0.00e+00	759.00
IUUC-Vvi-131592	Vitis vinifera	27.81	2.00e-06	48.90
IUUC-Xtr-132279	Xenopus tropicalis	60.12	8.00e-174	603.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence