iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-042321

Ensembl Protein ID

ENSGACP00000022560.1

UniProt Accession

G3PY71; G3PY71_GASAC

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000017071.1	ENSGACT00000022603.1	ENSGACP00000022560.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.00e-15	55.6	101	156

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L++kkGd  ++i  ++++++W+++ +  +g +G +P+n+v+ ++
   Q: 101  FVALYDYEARTSDDLSFKKGDRFQII--NNTEGDWWEARSINTGEKGYIPSNYVAPAD 156
           679***********************..8999**********************9875 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MGCVRSKEDK GSAPGAVKYR PDNSTPNNSH LGHYGPDPTL MGHSPAMKTH NNSYNSHAAA 60
LTPFGGASSI MTPFGGASTS FTSVAVSSPF PGVITGGVTF FVALYDYEAR TSDDLSFKKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTTGCG TCCGGAGCAA AGAGGACAAG GGCTCGGCGC CCGGCGCTGT GAAGTACCGG 60
CCCGACAACT CCACGCCGAA CAACTCCCAC CTGGGCCACT ACGGGCCCGA CCCCACCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002374	Ailuropoda melanoleuca	83.64	0.00e+00	926.00
IUUC-Apl-004032	Anas platyrhynchos	86.16	0.00e+00	962.00
IUUC-Aca-004255	Anolis carolinensis	84.85	0.00e+00	970.00
IUUC-Ame-010954	Astyanax mexicanus	90.91	0.00e+00	1050.00
IUUC-Bta-013503	Bos taurus	83.97	0.00e+00	924.00
IUUC-Cja-019694	Callithrix jacchus	83.61	0.00e+00	922.00
IUUC-Cfa-020402	Canis familiaris	83.79	0.00e+00	932.00
IUUC-Cpo-022506	Cavia porcellus	83.42	0.00e+00	925.00
IUUC-Csa-023713	Chlorocebus sabaeus	83.97	0.00e+00	928.00
IUUC-Dre-027978	Danio rerio	91.07	0.00e+00	1011.00
IUUC-Dno-029897	Dasypus novemcinctus	82.61	0.00e+00	824.00
IUUC-Dor-030202	Dipodomys ordii	92.48	0.00e+00	887.00
IUUC-Eca-034157	Equus caballus	83.61	0.00e+00	927.00
IUUC-Eeu-034950	Erinaceus europaeus	70.68	4.00e-153	533.00
IUUC-Fca-036233	Felis catus	83.61	0.00e+00	956.00
IUUC-Fal-037461	Ficedula albicollis	85.43	0.00e+00	972.00
IUUC-Gmo-038929	Gadus morhua	91.49	0.00e+00	983.00
IUUC-Gga-041107	Gallus gallus	85.97	0.00e+00	960.00
IUUC-Hsa-047010	Homo sapiens	83.79	0.00e+00	938.00
IUUC-Lch-050239	Latimeria chalumnae	86.16	0.00e+00	983.00
IUUC-Lpe-051166	Leersia perrieri	36.95	2.00e-24	107.00
IUUC-Loc-052314	Lepisosteus oculatus	88.20	0.00e+00	957.00
IUUC-Laf-053517	Loxodonta africana	81.60	0.00e+00	911.00
IUUC-Mcc-055626	Macaca mulatta	83.97	0.00e+00	929.00
IUUC-Meu-056155	Macropus eugenii	75.39	0.00e+00	716.00
IUUC-Mga-059310	Meleagris gallopavo	85.97	0.00e+00	960.00
IUUC-Mmr-061652	Microcebus murinus	81.97	0.00e+00	929.00
IUUC-Mdo-062963	Monodelphis domestica	83.61	0.00e+00	934.00
IUUC-Mmu-064128	Mus musculus	83.61	0.00e+00	940.00
IUUC-Mpu-065906	Mustela putorius furo	83.97	0.00e+00	932.00
IUUC-Mlu-067035	Myotis lucifugus	82.97	0.00e+00	920.00
IUUC-Nle-069041	Nomascus leucogenys	79.96	0.00e+00	880.00
IUUC-Opr-070299	Ochotona princeps	75.96	0.00e+00	813.00
IUUC-Ont-072337	Oreochromis niloticus	92.91	0.00e+00	1042.00
IUUC-Oan-072997	Ornithorhynchus anatinus	91.63	0.00e+00	897.00
IUUC-Ocu-074171	Oryctolagus cuniculus	82.33	0.00e+00	931.00
IUUC-Oga-087957	Otolemur garnettii	81.24	0.00e+00	919.00
IUUC-Oar-089670	Ovis aries	83.06	0.00e+00	930.00
IUUC-Ptr-091352	Pan troglodytes	83.79	0.00e+00	938.00
IUUC-Pan-092202	Papio anubis	83.97	0.00e+00	929.00
IUUC-Psi-093310	Pelodiscus sinensis	85.79	0.00e+00	976.00
IUUC-Pma-094232	Petromyzon marinus	85.84	0.00e+00	857.00
IUUC-Pfo-097076	Poecilia formosa	89.11	0.00e+00	1022.00
IUUC-Pab-098301	Pongo abelii	90.16	0.00e+00	896.00
IUUC-Pva-102592	Pteropus vampyrus	78.51	0.00e+00	880.00
IUUC-Rno-105544	Rattus norvegicus	82.51	0.00e+00	929.00
IUUC-Sar-113364	Sorex araneus	78.51	0.00e+00	865.00
IUUC-Tgu-117380	Taeniopygia guttata	85.43	0.00e+00	972.00
IUUC-Tru-117784	Takifugu rubripes	92.34	0.00e+00	1035.00
IUUC-Ttr-128893	Tursiops truncatus	84.15	0.00e+00	931.00
IUUC-Vpa-130060	Vicugna pacos	82.51	0.00e+00	927.00
IUUC-Xtr-132322	Xenopus tropicalis	84.67	0.00e+00	961.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence