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Tag Content
UUCD2 ID IUUC-Itr-048892
UUCD1 version UUC-SpT-00714
Ensembl Protein ID ENSSTOP00000001658.2
UniProt Accession I3LZC4; I3LZC4_ICTTR
Genbank Protein ID ENSSTOP00000001658
Protein Name Uncharacterized protein
Genbank Nucleotide ID AGTP01046158
Gene Name USP19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSTOG00000001848.2 ENSSTOT00000001858.2 ENSSTOP00000001658.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.10e-115 384.6 585 1302
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl NlgNtC+mNSv+Q+Lsn++elr+++++ +++ ++n +np ++ g+l+  ++ l+++lwk++++a++p++l+++++++a++f+g
   Q: 585  TGLVNLGNTCFMNSVIQSLSNTRELRDFFHDrSFEAEINYNNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTG 671
           7*****************************999****************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d   ++de     a++++k++n+s+i+dlFqgq+ks+++c+ c++vs +++p
   Q: 672  YAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSD--GRPDEvvaeeAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDP 756
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           fl+l++p+p+k++  +                                                                       
   Q: 757  FLYLPVPLPQKQKVLPVfyfarephskpikflvsvskenssvsevldslsqsvhvkpenlrlaeviknrfhriflpshsldtvspsd 843
           ************87666********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 844  mllcfellspelakervvvlevqqrpqvpsipiskcaacqrkqqsedeklkrctrcyrvgycnqlcqkthwpdhkglcrpenigypf 930
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 931  lvsvpasrltyarlaqllegyarysvsvfqppfqpgrmalesqspgcttllsnssleagdsekdstqppelqlvtsvaegdmgvpqm 1017
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1018 waspdrcpvpstsgissemltsgpiegtslppvervsrpeaavpgyqhpseainahtpqffiykidasnreqrledkgetplelgdd 1104
           *************************************************************************************** PP
   S: 186  ..........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevL 230
                                                     +l++cL+ ft++e l  e+++yc++ck+++ea+k+l l++lP+vL
   Q: 1105 cslalvwrnnerlqefvlvdskdlecaedpgsageaaraghfTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVL 1191
           *************************************************************************************** PP
   S: 231  ilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk........Wll 308
           i++LkRfsf++  +++ kin+ vefp + Ldls+fc+ ++e+q    +Y+L+av++H+G++ +GHY+a+++  +++        W l
   Q: 1192 IVQLKRFSFRSFIWRD-KINDLVEFPVRnLDLSKFCIGQKEEQ--LPSYDLYAVINHYGGMIGGHYTACARLPNDRssqrsdvgWRL 1275
           ************8886.**********9**********99888..9**************************544445566777*** PP
   S: 309  fdDskVtevkeeevleetgstaYvlfYkrr 338
           fdDs+Vt+v+e++v++   + aYvlfY+rr
   Q: 1276 FDDSTVTTVDESQVVT---RYAYVLFYRRR 1302
           ****************...********996 PP
   
Organism Ictidomys tridecemlineatus
Protein Sequence
(Fasta)
MSGGASATGP RRGPPGLEEA TSKKKQKDRA NQESKDGDPR RGGNGIPRVF MASFLPSYWA 60
HRWGIGRLLI ISSLFFILLS GSVPTPQEEH TKEGNIPLTE LLLDWGQNEN EVIVKLRVGV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Itr-048892|DUB,USP|Ictidomys tridecemlineatus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCTGGCG GGGCCAGTGC CACAGGCCCA AGGAGAGGGC CCCCAGGACT GGAGGAGGCC 60
ACTAGTAAGA AGAAGCAGAA GGATAGAGCA AACCAGGAGA GCAAGGATGG AGATCCTAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Itr-048892|DUB,USP|Ictidomys tridecemlineatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR007052--CS_dom
IPR008978--HSP20-like_chaperone
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND
PROSITE

PS51203--CS
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2
Pfam

PF04969--CS
PF00443--UCH
PF01753--zf-MYND
Gene Ontology

GO:0005829--C:cytosol
GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0046872--F:metal ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1901799--P:negative regulation of proteasomal protein catabolic process
GO:0048642--P:negative regulation of skeletal muscle tissue development
GO:0050821--P:protein stabilization
GO:1900037--P:regulation of cellular response to hypoxia
GO:1904292--P:regulation of ERAD pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001999 Ailuropoda melanoleuca 89.26 0.00e+00 2245.00
IUUC-Apl-003368 Anas platyrhynchos 67.20 0.00e+00 1690.00
IUUC-Aca-004267 Anolis carolinensis 65.26 0.00e+00 1639.00
IUUC-Ame-010970 Astyanax mexicanus 71.69 0.00e+00 1339.00
IUUC-Bta-012905 Bos taurus 89.58 0.00e+00 2258.00
IUUC-Cel-018257 Caenorhabditis elegans 43.24 1.00e-91 331.00
IUUC-Cja-018789 Callithrix jacchus 88.94 0.00e+00 2386.00
IUUC-Cfa-021004 Canis familiaris 89.39 0.00e+00 2241.00
IUUC-Cpo-021529 Cavia porcellus 87.57 0.00e+00 2338.00
IUUC-Csa-024035 Chlorocebus sabaeus 91.98 0.00e+00 2245.00
IUUC-Cho-025036 Choloepus hoffmanni 80.68 0.00e+00 1213.00
IUUC-Cin-025451 Ciona intestinalis 43.67 3.00e-86 313.00
IUUC-Csv-025931 Ciona savignyi 36.30 8.00e-109 387.00
IUUC-Dre-028556 Danio rerio 69.85 0.00e+00 1307.00
IUUC-Dno-029240 Dasypus novemcinctus 89.61 0.00e+00 2092.00
IUUC-Dor-030495 Dipodomys ordii 94.40 0.00e+00 1261.00
IUUC-Ete-032741 Echinops telfairi 90.76 0.00e+00 1820.00
IUUC-Eca-033661 Equus caballus 89.62 0.00e+00 2363.00
IUUC-Eeu-034648 Erinaceus europaeus 89.36 0.00e+00 803.00
IUUC-Fca-035646 Felis catus 89.36 0.00e+00 2212.00
IUUC-Fal-037094 Ficedula albicollis 65.42 0.00e+00 1743.00
IUUC-Gmo-038869 Gadus morhua 71.78 0.00e+00 845.00
IUUC-Gga-041170 Gallus gallus 63.62 0.00e+00 1693.00
IUUC-Gac-041901 Gasterosteus aculeatus 66.64 0.00e+00 1323.00
IUUC-Ggo-044708 Gorilla gorilla 89.44 0.00e+00 2407.00
IUUC-Hsa-046791 Homo sapiens 93.61 0.00e+00 2055.00
IUUC-Lch-050456 Latimeria chalumnae 50.89 0.00e+00 1197.00
IUUC-Loc-052861 Lepisosteus oculatus 62.31 0.00e+00 1139.00
IUUC-Laf-053788 Loxodonta africana 88.70 0.00e+00 2278.00
IUUC-Mcc-055693 Macaca mulatta 88.19 0.00e+00 2306.00
IUUC-Meu-055921 Macropus eugenii 78.05 0.00e+00 1502.00
IUUC-Mga-059879 Meleagris gallopavo 65.78 0.00e+00 1739.00
IUUC-Mmr-060802 Microcebus murinus 90.32 0.00e+00 2435.00
IUUC-Mdo-061856 Monodelphis domestica 78.85 0.00e+00 1592.00
IUUC-Mmu-063874 Mus musculus 87.43 0.00e+00 2335.00
IUUC-Mpu-066166 Mustela putorius furo 89.68 0.00e+00 2230.00
IUUC-Nle-070161 Nomascus leucogenys 89.44 0.00e+00 2446.00
IUUC-Opr-071015 Ochotona princeps 91.92 0.00e+00 1897.00
IUUC-Ont-072308 Oreochromis niloticus 69.12 0.00e+00 1362.00
IUUC-Oan-072723 Ornithorhynchus anatinus 64.66 0.00e+00 1619.00
IUUC-Ocu-073938 Oryctolagus cuniculus 89.29 0.00e+00 2251.00
IUUC-Ola-086375 Oryzias latipes 69.96 0.00e+00 1328.00
IUUC-Oga-088297 Otolemur garnettii 89.52 0.00e+00 2335.00
IUUC-Oar-089675 Ovis aries 82.60 0.00e+00 1986.00
IUUC-Ptr-091621 Pan troglodytes 93.43 0.00e+00 2052.00
IUUC-Pan-092118 Papio anubis 89.04 0.00e+00 2322.00
IUUC-Pma-094154 Petromyzon marinus 52.02 4.00e-115 408.00
IUUC-Pfo-097246 Poecilia formosa 60.68 0.00e+00 1406.00
IUUC-Pab-098551 Pongo abelii 92.81 0.00e+00 2034.00
IUUC-Pca-100158 Procavia capensis 84.57 0.00e+00 2236.00
IUUC-Pva-103160 Pteropus vampyrus 89.20 0.00e+00 2305.00
IUUC-Rno-105355 Rattus norvegicus 87.70 0.00e+00 2346.00
IUUC-Sha-107057 Sarcophilus harrisii 71.72 0.00e+00 1792.00
IUUC-Sar-113011 Sorex araneus 88.33 0.00e+00 1473.00
IUUC-Ssc-115761 Sus scrofa 89.66 0.00e+00 2292.00
IUUC-Tgu-116956 Taeniopygia guttata 61.04 0.00e+00 823.00
IUUC-Tru-118739 Takifugu rubripes 69.62 0.00e+00 1353.00
IUUC-Tsy-118827 Tarsius syrichta 82.68 0.00e+00 1236.00
IUUC-Tni-119921 Tetraodon nigroviridis 60.89 0.00e+00 1388.00
IUUC-Tbe-128017 Tupaia belangeri 90.61 0.00e+00 1962.00
IUUC-Ttr-128869 Tursiops truncatus 88.69 0.00e+00 2294.00
IUUC-Uma-129498 Ustilago maydis 30.75 4.00e-89 323.00
IUUC-Vpa-130427 Vicugna pacos 93.16 0.00e+00 901.00
IUUC-Xtr-132734 Xenopus tropicalis 61.57 0.00e+00 1554.00
Created Date 25-Jun-2017

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